Annals of Internal Medicine tip sheet for May 8, 2012, online issue
Embargoed news for Annals of Internal Medicine
2012-05-08
(Press-News.org) 1. Evidence Review: Screening Women for Intimate Partner Violence May Have Benefits, Few Harms
Intimate partner violence, or IPV, includes a range of abusive behaviors perpetrated by someone who is in an intimate relationship with the victim. Abusive behaviors may include physical violence, sexual violence, rape, and psychological aggression – all of which have immediate health effects on the victim. While victims and perpetrators can be male or female, women are disproportionately victimized (up to 5.3 million women are affected each year in the U.S.). In 2004, the United States Preventive Services Task Force (USPSTF) found insufficient evidence to support screening women for IPV. To inform an update of its previous recommendation, the Task Force reviewed articles published since 2003 to determine the effectiveness of IPV screening and interventions for women in health care settings in reducing IPV and related health outcomes, the diagnostic accuracy of screening tools, and adverse effects of screening and interventions. The evidence shows that women assigned to screening versus usual care did not have statistically significant improvements in IPV or health outcomes. However, more women in the screened group discussed IPV with their clinician (44 percent versus 8 percent). Clinicians may use questionnaire or interview-type tools to screen women for IPV. According to published research, five of the 13 tools assessed demonstrated high diagnostic accuracy. Few studies reported adverse effects of screening and interventions for IPV, but a large randomized controlled trial indicated no difference in adverse effects between women who were screened and women who were not. But some women who are screened may experience discomfort, loss of privacy, emotional distress, and concerns about further abuse. These data will be used to develop an updated recommendation on screening for IPV.
2. Physician Counseling Increases Sun-Protective Behaviors Among Patients at Greatest Risk for Skin Cancer
Skin cancer is one of the most common types of cancer, affecting more than two million American each year. Having light skin, hair, and eyes increases a patient's risk for skin cancer, as does over-exposure to ultraviolet rays at an early age. The United States Preventive Services Task Force (USPSTF) recommends that physicians counsel children, adolescents, and young adults aged 10 to 24 years who have fair skin about skin cancer prevention. Evidence published since its 2003 recommendation statement suggest that counseling interventions in the primary care setting moderately increase the use of sun-protective behaviors among younger patients. Low-intensity interventions based on appearance proved effective. For example, physicians showed patients photos taken with a UV camera to demonstrate the extent to which UV rays can damage the skin. The Task Force recommendation applies to asymptomatic patients between the ages of 10 and 24 years with no history of skin cancer. There is insufficient evidence to determine if counseling interventions are effective for changing behavior in older adults.
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2012-05-08
Philadelphia, PA, May 7, 2012 – While active monitoring of serum prostate specific antigen (PSA) levels in men over 50 has greatly improved early detection of prostate cancer, prediction of clinical outcomes after diagnosis remains a major challenge. Researchers from the University of Pittsburgh School of Medicine have found that a genetic abnormality known as copy number variation (CNV) in prostate cancer tumors, as well as in the benign prostate tissues adjacent to the tumor and in the blood of patients with prostate cancer, can predict whether a patient will experience ...
2012-05-08
The requirement for efficient mosquito mass-rearing technology has been one of the major obstacles preventing the large scale application of the Sterile Insect Technique (SIT) against mosquitoes.
However, according to a new article in the next issue of the Journal of Medical Entomology, scientists at the Untited Nations Food and Agriculture Organization (FAO) and the International Atomic Energy Agency (IAEA) have developed a larval rearing unit based on the use of a stainless steel rack that is expected to be able to successfully rear 140,000–175,000 adult mosquitoes ...
2012-05-08
HOUSTON -- (May 7, 2012) – The deletion of part of a gene that plays a role in the synthesis of carnitine – an amino acid derivative that helps the body use fat for energy – may play a role in milder forms of autism, said a group of researchers led by those at Baylor College of Medicine (http://www.bcm.edu) and Texas Children's Hospital (http://www.texaschildrens.org).
"This is a novel inborn error of metabolism," said Dr. Arthur Beaudet (http://www.bcm.edu/genetics/index.cfm?pmid=10579), chair of molecular and human genetics at BCM and a physician at Texas Children's ...
2012-05-08
SEATTLE—The collaborative TEAMcare program for people with depression and either diabetes, heart disease, or both appears at least to pay for itself, according to a UW Medicine and Group Health Research Institute report in the May 7 Archives of General Psychiatry. Over two years, after accounting for the $1,224 per patient that the program cost, it may save as much as $594 per patient in outpatient costs.
"Also, over the course of two years, people who received the TEAMcare intervention had a mean of 114 more days free from depression than did the people who received ...
2012-05-08
Antipsychotic medications are increasingly prescribed in the US, but they can cause serious side effects including rapid weight gain, especially in children. In the first study of its kind, researchers at Zucker Hillside Hospital and the Feinstein Institute for Medical Research identified a gene that increases weight gain in those treated with commonly-used antipsychotic drugs. These findings were published in the May issue of Archives of General Psychiatry.
Second-generation antipsychotics (SGAs) were used as the treatment in this study. SGAs are commonly used to treat ...
2012-05-08
An intriguing clue to longevity lurks in the sexual maturation timetable of female mammals, Jackson Laboratory researchers and their collaborators report.
Jackson researchers including Research Scientist Rong Yuan, Ph.D., had previously established that mouse strains with lower circulating levels of the hormone IGF1 at age six months live longer than other strains. In research published May 7 in the Proceedings of the National Academy of Sciences, Yuan and colleagues report that females from strains with lower IGF1 levels also reach sexual maturity at a significantly ...
2012-05-08
STANFORD, Calif. — The cells that slough off from a cancerous tumor into the bloodstream are a genetically diverse bunch, Stanford University School of Medicine researchers have found. Some have genes turned on that give them the potential to lodge themselves in new places, helping a cancer spread between organs. Others have completely different patterns of gene expression and might be more benign, or less likely to survive in a new tissue. Some cells may even express genes that could predict their response to a specific therapy. Even within one patient, the tumor cells ...
2012-05-08
PULLMAN, Wash.—A new study finds that fetal exposure to the plastic additive bisphenol A, or BPA, alters mammary gland development in primates. The finding adds to the evidence that the chemical can be causing health problems in humans and bolsters concerns about it contributing to breast cancer.
"Previous studies in mice have demonstrated that low doses of BPA alter the developing mammary gland and that these subtle changes increase the risk of cancer in the adult," says Patricia Hunt, a geneticist in Washington State University's School of Molecular Biosciences. "Some ...
2012-05-08
Philadelphia, PA, May 7, 2012 -- Like their healthy peers, children with disabilities may spend too much time in front of a video screen. For children with cerebral palsy (CP), this leads to an even greater risk of being overweight or developing health issues such as diabetes or musculoskeletal disorders. A group of scientists has found that video games such as Nintendo's Wii offer an enjoyable opportunity to promote light to moderate physical activity in children with CP, and may have a role to play in rehabilitation therapy. Their research is published online today ...
2012-05-08
New research provides the strongest evidence to date that psychopathy is linked to specific structural abnormalities in the brain. The study, published in Archives of General Psychiatry and led by researchers at King's College London is the first to confirm that psychopathy is a distinct neuro-developmental sub-group of anti-social personality disorder (ASPD).
Most violent crimes are committed by a small group of persistent male offenders with ASPD. Approximately half of male prisoners in England and Wales will meet diagnostic criteria for ASPD. The majority of such men ...
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[Press-News.org] Annals of Internal Medicine tip sheet for May 8, 2012, online issue
Embargoed news for Annals of Internal Medicine