Researchers reveal an RNA modification influences thousands of genes
Genetic discovery will revolutionize understanding of gene expression
2012-05-18
(Press-News.org) ###
Weill Cornell Medical College
Weill Cornell Medical College, Cornell University's medical school located in New York City, is committed to excellence in research, teaching, patient care and the advancement of the art and science of medicine, locally, nationally and globally. Physicians and scientists of Weill Cornell Medical College are engaged in cutting-edge research from bench to bedside, aimed at unlocking mysteries of the human body in health and sickness and toward developing new treatments and prevention strategies. In its commitment to global health and education, Weill Cornell has a strong presence in places such as Qatar, Tanzania, Haiti, Brazil, Austria and Turkey. Through the historic Weill Cornell Medical College in Qatar, the Medical College is the first in the U.S. to offer its M.D. degree overseas. Weill Cornell is the birthplace of many medical advances — including the development of the Pap test for cervical cancer, the synthesis of penicillin, the first successful embryo-biopsy pregnancy and birth in the U.S., the first clinical trial of gene therapy for Parkinson's disease, and most recently, the world's first successful use of deep brain stimulation to treat a minimally conscious brain-injured patient. Weill Cornell Medical College is affiliated with NewYork-Presbyterian Hospital, where its faculty provides comprehensive patient care at NewYork-Presbyterian Hospital/Weill Cornell Medical Center. The Medical College is also affiliated with the Methodist Hospital in Houston. For more information, visit weill.cornell.edu.
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2012-05-18
In two back-to-back reports published online on 17 May in Cell, researchers have sequenced the genomes of 21 breast cancers and analysed the mutations that emerged during the tumours' development. The individual results are described below.
Led by researchers from the Wellcome Trust Sanger Institute, the team created a catalogue of all the mutations in the genomes of the 21 cancer genomes and identified the mutational processes that lead to breast cancer. They found that these mutations accumulate in breast cells over many years, initially rather slowly, but picking up ...
2012-05-18
Researchers at the SIB Swiss Institute of Bioinformatics and the EMBL-European Bioinformatics Institute have confirmed the long-held conjecture that studying the genes we share with other animals is a viable means of extrapolating information about human biology. The study, published in the open access journal PLoS Computational Biology, shows how bioinformatics makes it possible to test the conjecture.
Scientists have long looked to model species – mice, for example – to understand human biology. This is at the root of what is called the 'ortholog conjecture': the idea ...
2012-05-18
Imagine reading an entire book, but then realizing that your glasses did not allow you to distinguish "g" from "q." What details did you miss?
Geneticists faced a similar problem with the recent discovery of a "sixth nucleotide" in the DNA alphabet. Two modifications of cytosine, one of the four bases that make up DNA, look almost the same but mean different things. But scientists lacked a way of reading DNA, letter by letter, and detecting precisely where these modifications are found in particular tissues or cell types.
Now, a team of scientists from the University ...
2012-05-18
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LA JOLLA, CA----It turns out that when we eat may be as important as what we eat. Scientists at the Salk Institute for Biological Studies have found that regular eating times and extending the daily fasting period may override the adverse health effects of a high-fat diet and prevent obesity, diabetes and liver disease in mice.
In a paper published May 17 in Cell Metabolism, scientists from Salk's ...
2012-05-18
Researchers at the SIB Swiss Institute of Bioinformatics and the EMBL-European Bioinformatics Institute have confirmed the long-held belief that studying the genes we share with other animals is useful. The study, published today in the open access journal PLoS Computational Biology, shows how bioinformatics makes it possible to test the fundamental principles on which life science is built.
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2012-05-18
Technology is helping communication companies merge telephone, television and Internet services, but a push to deregulate may leave some customers on the wrong side of the digital divide during this convergence, according to a Penn State telecommunications researcher.
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2012-05-18
MADISON – An international team of researchers has discovered how adding trace amounts of water can tremendously speed up chemical reactions—such as hydrogenation and hydrogenolysis—in which hydrogen is one of the reactants, or starting materials.
Led by Manos Mavrikakis, the Paul A. Elfers professor of chemical and biological engineering at the University of Wisconsin-Madison, and Flemming Besenbacher, a professor of physics and astronomy at the University of Aarhus, Denmark, the team published its findings in the May 18 issue of the journal Science.
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2012-05-18
For pregnant women, including those who are overweight and obese, following a healthy calorie controlled diet during pregnancy is safe and can reduce the risk of serious complications such as pre-eclampsia, diabetes and premature birth, finds a study published on bmj.com today.
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Pregnancy is thought ...
2012-05-18
The recent excesses of Wall Street may be big news but behind the headlines there's another story: When it comes to men and women stockbrokers, someone is taking home a bigger paycheck.
New research shows that women stockbrokers sometimes earn as much as 20 percent less than their male counterparts. "Stockbrokers are among the highest paid workers, yet they have the greatest gender inequality among all sales worker jobs," says Prof. Janice Fanning Madden, who conducted the research.
Her paper "Performance-Support Bias and the Gender Pay Gap Among Stockbrokers," will ...
2012-05-18
Dr. Joseph Kizior, Brookfield orthodontist, is pleased to offer an easy to use online appointment request form as a part of his practice's comprehensive website. The appointment request form is just one of the features on the Western Springs orthodontist's website designed to make dealing with Dr. Kizior's practice easy for patients.
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[Press-News.org] Researchers reveal an RNA modification influences thousands of genes
Genetic discovery will revolutionize understanding of gene expression
