PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Regional care systems to treat severe heart attacks improve survival rates

2012-06-05
(Press-News.org) North Carolina's coordinated, regional systems for rapid care improved survival rates of patients suffering from the most severe heart attack, according to research in the American Heart Association's journal, Circulation. Fewer ST -segment elevation myocardial infarction (STEMI) patients died when paramedics diagnosed them en route to hospitals and hospitals followed well-defined guidelines to quickly treat or transfer patients to facilities that performed artery-opening procedures, if needed. Death rates were 2.2 percent for patients treated to guideline standards and 5.7 percent for those who weren't, according to the study. Each year, nearly 300,000 people in the United States have a STEMI, which occurs when a blood clot completely blocks an artery to the heart. Permanent damage and disability can often be prevented by rapidly restoring the blood flow. Researchers analyzed the Regional Approach to Cardiovascular Emergencies (RACE) project, which involves regional care systems supporting voluntary coordination between emergency medical services (EMS) and all hospitals with emergency departments, including competing hospitals. "The most important care decisions for heart attack patients are made long before they get to the hospital," said James G. Jollis, M.D., the study's lead author and a professor of medicine and radiology at Duke University in Durham, N.C. "These coordinated care systems should be in every single hospital and every single EMS system in the country." Full implementation of the RACE system involved collaboration with thousands of healthcare professionals in 119 hospitals and more than 500 EMS agencies across North Carolina. Researchers reviewed records from July 2008 to December 2009, when more than 7,000 patients were treated (average age 59, 30 percent women). The EMS technician training and hospital guidelines in RACE are based on standards established through the American Heart Association's Mission: Lifeline® STEMI program. The goal of Mission: Lifeline STEMI is to have patients receiving artery-opening treatment within 90 minutes of their initial contact with the healthcare system. That first contact includes paramedics for patients who call 911 or the hospital emergency department for patients who use their own transportation to the hospital. "The paramedics have the ability to identify the STEMI and, when needed, call to alert the catheterization team from the ambulance," Jollis said. "When they arrive, the patient is taken straight to cath lab and most ― 52 percent ― are treated within 60 minutes." The STEMI care system also outlines when and how patients are transferred if they need treatment at a hospital that provides interventional cardiac catheterization. With RACE coordinated care systems, transferred patients got to cardiac surgery within 103 minutes of arriving at the first hospital, compared to 117 minutes prior to the system implementation. Furthermore, specialty cardiac centers in RACE accept all patients whether or not beds are available after surgery. "Our study shows coordinated regional STEMI systems save lives, no matter what unique challenges are posed by geographical or healthcare settings," said Christopher Granger, M.D., study co-author and a cardiologist at Duke. Building on the success of the North Carolina system, RACE investigators are working with Mission: Lifeline leaders to establish additional regional STEMI systems across the country. This program, the Mission: Lifeline® STEMI Systems Accelerator demonstration project, launches this summer in 20 regions across the country. "With appropriate coordination of emergency and hospital care, this system can be replicated and should be a model for the standard of care everywhere to save many more lives," Granger said. ###A complete list of RACE investigators and author disclosures are on the manuscript. The American Heart Association's Mission: Lifeline STEMI now includes more than 580 community-based systems, covering more than 60 percent of the U.S. population. Use the Mission: Lifeline systems of care interactive map to find a STEMI system near you. Statements and conclusions of study authors published in American Heart Association scientific journals are solely those of the study authors and do not necessarily reflect the association's policy or position. The association makes no representation or guarantee as to their accuracy or reliability. The association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific association programs and events. The association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and device corporations are available at www.heart.org/corporatefunding.

NR12 – 1083 (Circ/Jollis)


ELSE PRESS RELEASES FROM THIS DATE:

N.Y. prison inmates overuse and misuse antibiotic ointments, study says

2012-06-05
San Antonio, Texas, June 4, 2012 – Prisoners need education on the appropriate use of topical antibiotic products, according to a study released today at the 39th Annual Educational Conference and International Meeting of the Association for Professionals in Infection Control and Epidemiology (APIC). The first study to report on the widespread misuse of topical antibiotics among inmates entering prisons from other correctional facilities found that, among inmates who reported having used topical antibiotics during the previous six months, 59 percent of male and 40 percent ...

Genetics, rapid childhood growth and the development of obesity

2012-06-05
CHICAGO – A 38-year longitudinal study of New Zealanders suggests that individuals with higher genetic risk scores were more likely to be chronically obese in adulthood, according to a report published in the June issue of Archives of Pediatrics & Adolescent Medicine, a JAMA Network publication. Obesity is capable of being inherited and genome-wide association studies (GWASs) have started to uncover the molecular roots of heritability by identifying multiple single-nucleotide polymorphisms (SNPs) associated with higher adult body mass index (BMI), the authors write in ...

Rehospitalizations after surgical site infections add $10-65 million to health-care costs

2012-06-05
San Antonio, Texas, June 4, 2012 – Preventing further complications in patients who develop infections after surgery to replace a knee or hip could save the U.S. healthcare system as much as $65 million annually, according to an analysis presented today at the 39th Annual Educational Conference and International Meeting of the Association for Professionals in Infection Control and Epidemiology (APIC). The research team, led by Keith Kaye, MD, MPH, corporate director of Infection Prevention, Hospital Epidemiology and Antimicrobial Stewardship at Detroit Medical Center/Wayne ...

Brain scans prove Freud right: Guilt plays key role in depression

2012-06-05
Scientists have shown that the brains of people with depression respond differently to feelings of guilt – even after their symptoms have subsided. University of Manchester researchers found that the brain scans of people with a history of depression differed in the regions associated with guilt and knowledge of socially acceptable behaviour from individuals who never get depressed. The study – published in the journal Archives of General Psychiatry – provides the first evidence of brain mechanisms to explain Freud's classical observation that exaggerated guilt and ...

Largest statewide coordinated care effort improves survival, reduces time to heart attack treatment

2012-06-05
DURHAM, N.C.— An ambitious effort to coordinate heart attack care among every hospital and emergency service in North Carolina improved patient survival rates and reduced the time from diagnosis to treatment, according to Duke University Medical Center researchers who spearheaded the program. "When treating heart attacks, the most important care decisions need to take place before the patient is brought to the hospital," says James Jollis, M.D., a Duke cardiologist and first author of the findings published today in the journal Circulation. "These procedures should be ...

Study examines comparative effectiveness of rhythm control vs. rate control drug treatment

2012-06-05
CHICAGO – An observational study that examined the comparative effectiveness of rhythm control vs. rate control drug treatment on mortality in patients with atrial fibrillation (a rapid, irregular heart beat) suggests there was little difference in mortality within four years of treatment, but rhythm control may be associated with more effective long-term outcomes, according to a report published Online First by Archives of Internal Medicine, a JAMA Network publication. AF affects approximately 2.3 million Americans and 250,000 Canadians, and the condition has a complex ...

Families of kids with staph infections have high rate of drug-resistant germ

2012-06-05
Family members of children with a staph infection often harbor a drug-resistant form of the germ, although they don't show symptoms, a team of researchers from Washington University School of Medicine in St. Louis has found. The results are published in the June issue of Archives of Pediatrics & Adolescent Medicine. The investigators focused on family members of nearly 200 children who had Staphylococcus aureus infections in the skin and soft tissue, in areas such as the nose, armpits and/or groin. They found that of the more than 600 household members who lived with ...

Joslin researchers find 'good fat' activated by cold, not ephedrine

Joslin researchers find good fat activated by cold, not ephedrine
2012-06-05
BOSTON -- June 4, 2012 -- Researchers at Joslin Diabetes Center have shown that while a type of "good" fat found in the body can be activated by cold temperatures, it is not able to be activated by the drug ephedrine. The finding, published in today's issue of PNAS USA Early Edition, may lead to drugs or other methods aimed at activating the good fat, known as brown fat. When activated, brown fat burns calories and can help in the battle against obesity. "We propose that agents that work similarly to cold in activating brown fat specifically can provide promising approaches ...

New statistical model lets patient's past forecast future ailments

2012-06-05
Analyzing medical records from thousands of patients, statisticians have devised a statistical model for predicting what other medical problems a patient might encounter. Like how Netflix recommends movies and TV shows or how Amazon.com suggests products to buy, the algorithm makes predictions based on what a patient has already experienced as well as the experiences of other patients showing a similar medical history. "This provides physicians with insights on what might be coming next for a patient, based on experiences of other patients. It also gives a predication ...

Hands-on research

2012-06-05
PASADENA, Calif.—A nuzzle of the neck, a stroke of the wrist, a brush of the knee—these caresses often signal a loving touch, but can also feel highly aversive, depending on who is delivering the touch, and to whom. Interested in how the brain makes connections between touch and emotion, neuroscientists at the California Institute of Technology (Caltech) have discovered that the association begins in the brain's primary somatosensory cortex, a region that, until now, was thought only to respond to basic touch, not to its emotional quality. The new finding is described ...

LAST 30 PRESS RELEASES:

Development of a novel modified selective medium cefixime–tellurite-phosphate-xylose-rhamnose MacConkey agar for isolation of Escherichia albertii and its evaluation with food samples

KIST develops full-color-emitting upconversion nanoparticle technology for color displays with ultra-high color reproducibility

Towards a fully automated approach for assessing English proficiency

Increase in alcohol deaths in England an ‘acute crisis’

Government urged to tackle inequality in ‘low-carbon tech’ like solar panels and electric cars

Moffitt-led international study finds new drug delivery system effective against rare eye cancer

Boston stroke neurologist elected new American Academy of Neurology president

Center for Open Science launches collaborative health research replication initiative

Crystal L. Mackall, MD, FAACR, recognized with the 2025 AACR-Cancer Research Institute Lloyd J. Old Award in Cancer Immunology

A novel strategy for detecting trace-level nanoplastics in aquatic environments: Multi-feature machine learning-enhanced SERS quantification leveraging the coffee ring effect

Blending the old and the new: Phase-change perovskite enable traditional VCSEL to achieve low-threshold, tunable single-mode lasers

Enhanced photoacoustic microscopy with physics-embedded degeneration learning

Light boosts exciton transport in organic molecular crystal

On-chip multi-channel near-far field terahertz vortices with parity breaking and active modulation

The generation of avoided-mode-crossing soliton microcombs

Unlocking the vibrant photonic realm: A new horizon for structural colors

Integrated photonic polarizers with 2D reduced graphene oxide

Shouldering the burden of how to treat shoulder pain

Stevens researchers put glycemic response modeling on a data diet

Genotype-to-phenotype map of human pelvis illuminates evolutionary tradeoffs between walking and childbirth

Pleistocene-age Denisovan male identified in Taiwan

KATRIN experiment sets most precise upper limit on neutrino mass: 0.45 eV

How the cerebellum controls tongue movements to grab food

It’s not you—it’s cancer

Drug pollution alters migration behavior in salmon

Scientists decode citrus greening resistance and develop AI-assisted treatment

Venom characteristics of a deadly snake can be predicted from local climate

Brain pathway links inflammation to loss of motivation, energy in advanced cancer

Researchers discover large dormant virus can be reactivated in model green alga

New phase of the immune response uncovered

[Press-News.org] Regional care systems to treat severe heart attacks improve survival rates