How to improve health and reduce risk for dialysis patients
2010-10-01
(Press-News.org) Early Online Releases:
1. Depression Symptoms and Low Physical Activity May Keep Dialysis Patients from Working
Efforts to Improve Mood and Activity Might Help Patients Remain Employed
Many patients with kidney failure employed during the year before beginning dialysis are no longer employed early in their first year of treatment. A recent survey by Nancy Kutner, PhD (Emory University) and her colleagues indicates that depression and reduced physical activity may play a role. Among 585 dialysis patients who had worked in the previous year, only 191 (32.6%) continued working after initiating dialysis. The study revealed that only 12.1% of patients who remained employed had possible or probable depression, compared with 32.8% of patients who were no longer employed. In addition, patients who scored higher on questions related to their level of physical activity were more likely to continue working. "More attention to improving mood disorders and increasing usual activity levels among kidney disease patients might help them to maintain employment and would undoubtedly contribute to overall improvements in patients' quality of life," said Dr. Kutner. The article, entitled "Depressed Mood, Usual Activity Level, and Continued Employment after Starting Dialysis," will appear online at http://jasn.asnjournals.org/ on September 30, 2010, doi 10.2215/CJN.03980510.
2. Modifying Blood Access Reduces Kidney Disease Patients' Risk of Hospitalization
Patients Benefit by Switching from Catheters to Arteriovenous Access
For kidney disease patients who must undergo dialysis, experts recommend an arteriovenous blood access, preferably a fistula which is created by connecting a vein and an artery to form a long-lasting site through which blood can be removed and returned. Many patients become complacent with using a catheter instead—even though catheters are associated with increased infections, complications, and deaths—because they do not require advanced surgery and attachment to the dialysis machine does not require needles. A new study shows that patients who convert from catheters to arteriovenous access have a lower risk of being hospitalized for any reason. Eduardo Lacson Jr., MD (Fresenius Medical Care, North America) and his colleagues studied the health of 70,852 dialysis patients, 19,792 of whom had catheters. Over a 4-month period, 10.3% of these converted to arteriovenous access. Compared with patients who kept their catheters, patients who converted had a similarly lower risk (by about 30%) of being hospitalized within one year as patients who were dialyzing with arteriovenous accesses during the entire study period, while patients with arteriovenous access who switched to catheters were 22% more likely to be hospitalized. The article, entitled "Change in Vascular Access and Hospitalization Risk in Long-Term Hemodialysis Patients," will appear online at http://jasn.asnjournals.org/ on September 30, 2010, doi 10.2215/CJN.08961209.
###
For a complete list of disclosures and additional information, please contact Shari Leventhal at sleventhal@asn-online.org or 202-416-0658.
The content of this article does not reflect the views or opinions of The American Society of Nephrology (ASN). Responsibility for the information and views expressed therein lies entirely with the author(s). ASN does not offer medical advice. All content in ASN publications is for informational purposes only, and is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects. This content should not be used during a medical emergency or for the diagnosis or treatment of any medical condition. Please consult your doctor or other qualified health care provider if you have any questions about a medical condition, or before taking any drug, changing your diet or commencing or discontinuing any course of treatment. Do not ignore or delay obtaining professional medical advice because of information accessed through ASN. Call 911 or your doctor for all medical emergencies.
Founded in 1966, the American Society of Nephrology (ASN) is the world's largest professional society devoted to the study of kidney disease. Comprised of 11,000 physicians and scientists, ASN continues to promote expert patient care, to advance medical research, and to educate the renal community. ASN also informs policymakers about issues of importance to kidney doctors and their patients. ASN funds research, and through its world-renowned meetings and first-class publications, disseminates information and educational tools that empower physicians.
END
ELSE PRESS RELEASES FROM THIS DATE:
2010-10-01
The ability to efficiently generate patient-specific stem cells from differentiated cells and then reliably direct them to form specialized cells (like neurons or muscle) has tremendous therapeutic potential for replacing diseased or damaged tissues. However, despite some successes, there have been significant limitations associated with existing methods used to generate human induced pluripotent stem cells (iPSCs).
Now, a study published by Cell Press on September 30th in the journal Cell Stem Cell presents a novel strategy for creating iPSCs that exhibits some significant ...
2010-10-01
One in seven couples worldwide has difficulty conceiving a child, and male infertility is thought to account for nearly half of those cases. Although the cause of male infertility is often unknown, scientists have now discovered a genetic alteration that disrupts sperm production in otherwise healthy men. The research, published by Cell Press on September 30th in the American Journal of Human Genetics, provides new insight into one cause of male infertility.
"Many genes are known to be essential for the production of sperm, but there are surprisingly few single gene changes ...
2010-10-01
Paleontologists have unearthed the first extinct penguin with preserved evidence of scales and feathers. The 36-million-year-old fossil from Peru shows the new giant penguin's feathers were reddish brown and grey, distinct from the black tuxedoed look of living penguins.
The new species, Inkayacu paracasensis, or Water King, was nearly five feet tall or about twice the size of an Emperor penguin, the largest living penguin today.
"Before this fossil, we had no evidence about the feathers, colors and flipper shapes of ancient penguins. We had questions and this was ...
2010-10-01
RIVERSIDE, Calif. – Last year, 720 people in the United States became infected with West Nile virus, a potentially serious illness that is spread through the bite of a mosquito – the Culex mosquito – that has first fed on infected birds. Such mosquitoes have the virus eventually located in their salivary glands and transmit the disease to humans and animals when they bite to draw blood.
To understand the genetic makeup of the Culex mosquito, and how the insect is able to transmit this and other viruses, an international team of scientists, led by geneticists at the ...
2010-10-01
MEDFORD/SOMERVILLE, Mass.--Researchers from Tufts University School of Engineering and MIT have reported a new way to biosynthesize important precursors to the potent anti-cancer compound Taxol in an engineered strain of E. coli bacteria.
The findings are significant steps on the way to achieving cost-effective, large-scale production of Taxol and the effort to design new Taxol-like pharmaceuticals.
The work is reported in the October 1, 2010, issue of the journal Science.
Taxol (paclitaxel) and its structural analogs are among the most powerful and commercially ...
2010-10-01
Chestnut Hill, Mass. (9/30/2010) – Scientists have sequenced the genome of the Southern house mosquito, providing new insights into the most diverse and widespread of three groups of disease-bearing mosquitoes and shedding new light on the transmission of mosquito-borne diseases such as malaria, encephalitis, West Nile virus and filariasis, international teams of researchers report in the upcoming edition of the journal Science.
Breeding in drains, cesspools and other polluted water bodies, Culex quinquefasciatus feeds on blood from birds, livestock and humans and transmits ...
2010-10-01
Ethnicity is a contributing risk factor of cardiovascular problems in kidney recipients of South Asian origin post-transplant, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN).
South Asians comprise 25% of all Canadian visible minorities and have a higher risk for cardiovascular disease in the general population. However, the risk of cardiovascular events has never been studied in this minority population.
To investigate, G.V. Ramesh Prasad, MBBS, MSc, FRCPC, FACP, FASN (University of Toronto) and ...
2010-10-01
A North Carolina State University researcher is part of a team that has discovered fossilized feathers from a giant penguin that lived near the Equator more than 36 million years ago. These feathery fossils reveal color patterns in an ancient extinct penguin species, and offer clues to how modern penguin feathers evolved.
The penguin in question – dubbed Inkayacu paracasensis, or Water King – dates from the late Eocene period and stood almost five feet tall. The fossil was discovered near the Paracas Reserve, located along the eastern coastline of Peru. A research team ...
2010-10-01
COLUMBIA, Mo.– It might seem obvious that a dinosaur's leg bone connects to the hip bone, but what came between the bones has been less obvious. Now, researchers at the University of Missouri and Ohio University have found that dinosaurs had thick layers of cartilage in their joints, which means they may have been considerably taller than previously thought. The study is being published this week in the journal PLoS ONE (Public Library of Science).
"Our study of the limbs of modern-day relatives of dinosaurs shows that dinosaurs were significantly taller than original ...
2010-10-01
CAMBRIDGE, Mass. -- MIT researchers and collaborators from Tufts University have now engineered E. coli bacteria to produce large quantities of a critical compound that is a precursor to the cancer drug Taxol, originally isolated from the bark of the Pacific yew tree. The tree's bacteria can produce 1,000 times more of the precursor, known as taxadiene, than any other engineered microbial strain.
The technique, described in the Oct. 1 issue of Science, could bring down the manufacturing costs of Taxol and also help scientists discover potential new drugs for cancer and ...
LAST 30 PRESS RELEASES:
[Press-News.org] How to improve health and reduce risk for dialysis patients