(Press-News.org) Philadelphia, PA, July 19, 2012 – Neuroeconomics experts and guest editors of the Biological Psychiatry special issue Carla Sharp, John Monterosso, and P. Read Montague in an introductory paper define neuroeconomics as "an interdisciplinary field that brings together psychology, economics, neuroscience, and computational science to investigate how people make decisions."
Neuroeconomics is a relatively new field that traditionally has studied the decision-making process of healthy individuals. It does so by using neuroimaging techniques in conjunction with behavioral economic experiments. For example, an experiment may involve a gambling task where individuals must repeatedly choose between two options, one considered risky and one safe. The corresponding brain activity occurring during each choice is recorded and analyzed, allowing researchers to study and understand the underlying processes of those decisions.
In healthy individuals, investigators study optimal decision-making strategies. However, in psychiatric populations, studying alterations in decision-making can provide insights into the neurobiology underlying "real world" functional impairments. Dr. Sharp commented that "neuroeconomics provides an interdisciplinary platform for researchers to study reward-related decision-making as it relates to psychiatric disorder across multiple levels of explanation." Thus, in this introductory paper to the special issue, the authors detail the reasons why neuroeconomics is a useful approach to study psychiatric behavior.
Abnormal decision-making has been identified in many psychiatric disorders, including substance abuse and addiction disorders, depression, anxiety, and attention-deficit/hyperactivity disorder. Individuals with these disorders tend to respond differently to rewards and losses, which includes how much value they place on immediate versus delayed rewards, and even how choices are altered based on the potential size of the reward. Neuroeconomics can be used to study these differential patterns of decision-making, which theoretically, could later be used to develop improved treatments.
Neuroeconomics may also advance psychiatry in a larger way by promoting the development of a new classification system based on linking pathology in brain systems to behavioral disturbances. This is a lofty and important goal for psychiatry, highlighted by the National Institute of Mental Health Strategic Plan that identifies the need for "new ways of classifying mental disorders based on dimensions of observable behavior and neurobiological measures". This would move the field beyond the categorical classification system that has been used for decades to diagnose and study psychiatric disorders.
"Neuroeconomics is one of the hottest areas in cognitive neuroscience. We are extremely pleased to have leaders in this field discuss its important implications for psychiatry," said John Krystal, Editor of Biological Psychiatry.
For now, the authors note that the "application of neuroeconomics to psychopathology has only just begun," but the papers in this special issue detail how and why this field can and should move forward.
###
The introductory paper is entitled "Neuroeconomics: A Bridge for Translational Research" by Carla Sharp, John Monterosso, and P. Read Montague (doi: 10.1016/j.biopsych.2012.02.029). The article appears in Biological Psychiatry, Volume 72, Issue 2 (July 15, 2012), published by Elsevier.
Notes for editors
Full text of the article is available to credentialed journalists upon request; contact Rhiannon Bugno at +1 214 648 0880 or Biol.Psych@utsouthwestern.edu. Journalists wishing to interview the authors may contact Carla Sharp at +1 713 743 8612 or csharp2@uh.edu.
The authors' affiliations, and disclosures of financial and conflicts of interests are available in the article.
John H. Krystal, M.D., is Chairman of the Department of Psychiatry at the Yale University School of Medicine and a research psychiatrist at the VA Connecticut Healthcare System. His disclosures of financial and conflicts of interests are available here.
About Biological Psychiatry
Biological Psychiatry is the official journal of the Society of Biological Psychiatry, whose purpose is to promote excellence in scientific research and education in fields that investigate the nature, causes, mechanisms and treatments of disorders of thought, emotion, or behavior. In accord with this mission, this peer-reviewed, rapid-publication, international journal publishes both basic and clinical contributions from all disciplines and research areas relevant to the pathophysiology and treatment of major psychiatric disorders.
The journal publishes novel results of original research which represent an important new lead or significant impact on the field, particularly those addressing genetic and environmental risk factors, neural circuitry and neurochemistry, and important new therapeutic approaches. Reviews and commentaries that focus on topics of current research and interest are also encouraged.
Biological Psychiatry is one of the most selective and highly cited journals in the field of psychiatric neuroscience. It is ranked 5th out of 129 Psychiatry titles and 16th out of 243 Neurosciences titles in the Journal Citations Reports® published by Thomson Reuters. The 2011 Impact Factor score for Biological Psychiatry is 8.283.
About Elsevier
Elsevier is a world-leading provider of scientific, technical and medical information products and services. The company works in partnership with the global science and health communities to publish more than 2,000 journals, including The Lancet and Cell, and close to 20,000 book titles, including major reference works from Mosby and Saunders. Elsevier's online solutions include ScienceDirect, Scopus, Reaxys, MD Consult and Mosby's Nursing Suite, which enhance the productivity of science and health professionals, and the SciVal suite and MEDai's Pinpoint Review, which help research and health care institutions deliver better outcomes more cost-effectively.
A global business headquartered in Amsterdam, Elsevier employs 7,000 people worldwide. The company is part of Reed Elsevier Group PLC, a world-leading publisher and information provider, which is jointly owned by Reed Elsevier PLC and Reed Elsevier NV. The ticker symbols are REN (Euronext Amsterdam), REL (London Stock Exchange), RUK and ENL (New York Stock Exchange).
Media contact
Rhiannon Bugno
Editorial Office, Biological Psychiatry
+1 214 648 0880
biol.psych@utsouthwestern.edu
END
Belgian scientists of the Institute of Tropical Medicine (ITM) in Antwerp, Belgium made a breakthrough in bridging high tech molecular biology research on microbial pathogens and the needs of the poorest of the poor. After sequencing the complete genome of Leishmania donovani (a parasite causing one of the most important tropical diseases after malaria) in hundreds of clinical isolates, they identified a series of mutations specific of 'superparasites' and developed a simple assay that should allow tracking them anywhere. This EU-funded research was done in collaboration ...
Synapses are modified through learning. Up until now, scientists believed that a particular form of synaptic plasticity in the brain's hippocampus was responsible for learning spatial relations. This was based on a receptor type for the neurotransmitter glutamate: the NMDA receptor. Researchers at the Max Planck Institute for Medical Research in Heidelberg and Oxford University have now observed that mice develop a spatial memory, even when the NMDA receptor-transmitted plasticity is switched off in parts of their hippocampus. However, if these mice have to resolve a conflict ...
Marine bacteria of the Roseobacter clade are found to be spread widely throughout the oceans of this planet from the tropics to as far as Antarctica. They live freely in the water, in sediments and as symbiotic partners of algae. Special photosynthetic pigments are responsible for their pink colour. Marine bacteria distinguish themselves through an unusually diverse metabolism, which opens interesting opportunities for biotechnological applications. A reconstruction of their evolutionary development will provide a key for scientists to understand the secret for their ecological ...
AMHERST, Mass. – Physicists Andrea Pocar and Krishna Kumar of the University of Massachusetts Amherst, part of an international research team, recently reported results of an experiment conducted at the Enriched Xenon Observatory (EXO), located in a salt mine one-half mile under Carlsbad, New Mexico, part of a decades-long search for evidence of the elusive neutrino-less double-beta decay of Xenon-136.
Pocar, Kumar and the team of 60 scientists using an instrument called the EXO-200 detector, succeeded in setting a new lower limit for the half-life of this ephemeral ...
A new model shows how an elusive type of black hole can be formed in the gas surrounding their supermassive counterparts. In research published in the Monthly Notices of the Royal Astronomical Society, scientists from the American Museum of Natural History, the City University of New York, the Jet Propulsion Laboratory of the California Institute of Technology, and the Harvard-Smithsonian Center for Astrophysics propose that intermediate-mass black holes—light-swallowing celestial objects with masses ranging from hundreds to many thousands of times the mass of the Sun—can ...
A joint study carried out by The University of Nottingham and the multinational food company Unilever has found for the first time that fat in food can reduce activity in several areas of the brain which are responsible for processing taste, aroma and reward.
The research, now available in the Springer journal Chemosensory Perception, provides the food industry with better understanding of how in the future it might be able to make healthier, less fatty food products without negatively affecting their overall taste and enjoyment. Unveiled in 2010, Unilever's Sustainable ...
What do you get when you dissect 10 000 fruit-fly larvae? A team of researchers led by the EMBL-European Bioinformatics Institute (EMBL-EBI) in the UK and the Max Planck Institute of Immunobiology and Epigenetics (MPI) in Freiburg, Germany has discovered a way in which cells can adjust the activity of many different genes at once. Their findings, published in the journal Science, overturn commonly held views and reveal an important mechanism behind gender differences.
Asifa Akhtar's laboratory, previously at EMBL now at MPI, studies precisely how flies regulate an important ...
The sun emitted a mid-level solar flare on July 19, 2012, beginning at 1:13 AM EDT and peaking at 1:58 AM. Solar flares are gigantic bursts of radiation that cannot pass through Earth's atmosphere to harm humans on the ground, however, when strong enough, they can disrupt the atmosphere and degrade GPS and communications signals.
The flare is classified as an M7.7 flare. This means it is weaker than the largest flares, which are classified as X-class. M-class flares can cause brief radio communications blackouts at the poles.
Increased numbers of flares are currently ...
PHILADELPHIA - Silymarin, an extract of milk thistle commonly used to treat chronic liver disease by millions of people around the World, does not offer significant improvements for patients, according to a new study conducted by a nationwide group of researchers including faculty at the Perelman School of Medicine at the University of Pennsylvania. Milk thistle fruit extracts have been widely used by patients in treating liver disease based on previous evidence showing that it has anti-inflammatory, anti-oxidant, and potentially anti-viral properties. However, the new ...
A new study from Lund University in Sweden has opened the way for new approaches to slowing the development of AIDS in HIV-1-infected patients. It is hoped that this could lead to better treatment methods and preventive measures to combat HIV and AIDS.
The findings have just been published in the distinguished scientific journal New England Journal of Medicine.
The most common type of the virus that causes AIDS – HIV-1 – is less aggressive when it infects a person already carrying the milder HIV-2. The study looked at how the disease developed in those who had been ...