PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Novel chewing gum formulation helps prevent motion sickness

2012-10-17
(Press-News.org) Arlington, Va. — A new prototype for medicated chewing gum has been developed for motion sickness that may offer many advantages over conventional oral solid dosage forms. About 33 percent of people are susceptible to motion sickness in mild circumstances and 66 percent are affected in more severe conditions. This research is being presented at the 2012 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition in Chicago, Ill., Oct. 14 – 18, an international event anticipating more than 8,000 attendees.

Lead researcher Mohsen Sadatrezaei of RoshaDarou Co. and a team of researchers consisting of Niloufar Pouyan, Zoherh JafariAzar and Alireza Ghaffari from the Islamic Azad University School of Pharmaceutical Sciences (Tehran, Iran), have developed a medicated gum that will improve patient compliance and faster absorption through the cheek, which will alleviate motion sickness sooner. A sensory panel was used to test faster absorption through the buccal cavity, which will result in earlier onset of action against motion sickness. Panelists also ranked the gum on bitterness and easiness to chew.

"The main challenge in delivering drugs through chewing gum is masking the bitter taste of its active ingredient," said Sadatrezaei. "We have formulated dimenhydrinate as chewing gum with acceptable taste and sensory attributes. Dimenhydrinate is among the best drug candidates for treatment of motion sickness, providing a comfortable and acceptable drug delivery."

The final formulation has great potential for dimenhydrinate chewing gum commercialization. Moreover, the outcome of the study can be used as a platform to incorporate other active ingredients with objectionable taste into chewing gum.

###The 2012 AAPS Annual Meeting and Exposition, the world's largest pharmaceutical sciences meeting, aims to improve global health through advances in pharmaceutical sciences. The meeting features more than 90 programming sessions, including more than 50 symposia and roundtables.

AAPS is pleased to announce that our smartphone application is available at the 2012 AAPS Annual Meeting and Exposition. This application can assist meeting attendees with anything and everything they need to navigate the conference at their fingertips.

Editor's Note: All press must provide press credentials to attend this meeting. The deadline for online media registration is Oct. 5. After that date, media must register on-site. For media registration, please contact Kimberly Brown at BrownK@aaps.org or (703) 248-4772. To schedule an interview with Mohsen Sadatrezaei or for any other press inquiry, please contact Hillarie Turner or Dana Korsen at aaps@ecius.net or 202-296-2002.

About AAPS: The American Association of Pharmaceutical Scientists is a professional, scientific society of approximately 11,000 members employed in academia, industry, government and other research institutes worldwide. Founded in 1986, AAPS provides a dynamic international forum for the exchange of knowledge among scientists to serve the public and enhance their contributions to health. AAPS offers timely scientific programs, on-going education, information resources, opportunities for networking, and professional development. For more information, please visit www.aaps.org. Follow us on Twitter @AAPSComms; official Twitter hashtag for the meeting is: #AAPS2012.


ELSE PRESS RELEASES FROM THIS DATE:

Discovery of two opposite ways humans voluntarily forget unwanted memories

Discovery of two opposite ways humans voluntarily forget unwanted memories
2012-10-17
If only there were a way to forget that humiliating faux pas at last night's dinner party. It turns out there's not one, but two opposite ways in which the brain allows us to voluntarily forget unwanted memories, according to a study published by Cell Press October 17 in the journal Neuron. The findings may explain how individuals can cope with undesirable experiences and could lead to the development of treatments to improve disorders of memory control. "This study is the first demonstration of two distinct mechanisms that cause such forgetting: one by shutting down ...

Daily multivitamins reduce risk of cancer in men

2012-10-17
Boston, MA – A daily multivitamin can help a man reduce his risk of cancer, according to new research from Brigham and Women's Hospital (BWH). The first-of-its kind study will be presented October 17 at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research and published online the same day in the Journal of the American Medical Association. "The Physicians' Health Study II is the first clinical trial to test the affects of multivitamins on a major disease such as cancer," said lead author J. Michael Gaziano, MD, chief of the Division ...

Daily sedation interruption for critically ill patients does not improve outcomes

2012-10-17
CHICAGO – For critically ill patients receiving mechanical ventilation, daily sedation interruption did not reduce the duration of mechanical ventilation or appear to offer any benefit to patients, and may have increased both sedation and analgesic use and nurse workload, according to a study appearing in JAMA. The study is being published early online to coincide with its presentation at the European Society of Intensive Care Medicine Annual Congress. "Critically ill patients wean more quickly from mechanical ventilation, with lower risk of delirium, when clinicians ...

Kaiser Permanente study finds efforts to establish exercise as a vital sign prove valid

2012-10-17
PASADENA, Calif., Oct. 17, 2012 — Kaiser Permanente has created a new electronic Exercise Vital Sign initiative to systematically record patients' physical activity in their electronic health records. The new feature is successfully compiling accurate and valuable information that can help clinicians better treat and counsel patients about their lifestyles, according to a Kaiser Permanente study published in the journal Medicine & Science in Sports & Exercise. The study examined the electronic health records of 1,793,385 Kaiser Permanente Southern California patients ...

Multivitamin use among middle-aged, older men results in modest reduction in cancer

2012-10-17
CHICAGO – In a randomized trial that included nearly 15,000 male physicians, long-term daily multivitamin use resulted in a modest but statistically significant reduction in cancer after more than a decade of treatment and follow-up, according to a study appearing in JAMA. The study is being published early online to coincide with its presentation at the Annual American Association for Cancer Research Frontiers in Cancer Prevention Research meeting. "Multivitamins are the most common dietary supplement, regularly taken by at least one-third of U.S. adults. The traditional ...

UC Davis researchers clarify process controlling night vision

2012-10-17
On the road at night or on a tennis court at dusk, the eye can be deceived. Vision is not as sharp as in the light of day, and detecting a bicyclist on the road or a careening tennis ball can be tough. New research reveals the key chemical process that corrects for potential visual errors in low-light conditions. Understanding this fundamental step could lead to new treatments for visual deficits, or might one day boost normal night vision to new levels. Like the mirror of a telescope pointed toward the night sky, the eye's rod cells capture the energy of photons - ...

Extreme 'housework' cuts the life span of female Komodo dragons

Extreme housework cuts the life span of female Komodo dragons
2012-10-17
Extreme 'housework' cuts the life span of female Komodo Dragons An international team of researchers has found that female Komodo Dragons live half as long as males on average, seemingly due to their physically demanding 'housework' such as building huge nests and guarding eggs for up to six months. The results provide important information on the endangered lizards' growth rate, lifestyle and population differences, which may help plan conservation efforts. The Komodo dragon is the world's largest lizard. Their formidable body size enables them to serve as top predators ...

Hard evidence grows for including meditation in government-sponsored health programs

Hard evidence grows for including meditation in government-sponsored health programs
2012-10-17
More people still die from cardiovascular disease than any other illness. Dubbed the number one killer and the silent killer, modern medicine has been researching and incorporating complementary and alternative approaches to help treat and in some cases reverse and hopefully prevent this health problem at an earlier stage of the disease. One of those modalities is meditation. A new research review paper on the effects of the stress-reducing Transcendental Meditation (TM) technique on the prevention and treatment of heart disease among youth and adults provides the hard ...

The Internet of Things will transform our everyday

2012-10-17
Information technology and electronics are becoming entwined with our everyday lives in industry, the service sector, transport, logistics, health care, housing, education, and our leisure time, almost without our noticing it. The changes are already apparent to consumers in the energy sector, for example: remotely readable meters are rapidly becoming more common, enabling developments such as new pricing models that encourage the reduction of carbon dioxide emissions. The remote control of machines and devices is experiencing substantial growth and spreading to smaller ...

Active surveillance provides a viable alternative to surgery for small kidney masses

2012-10-17
Active surveillance of small kidney masses is a safe and effective alternative to immediate surgery, with similar overall and cancer specific survival rates, according to a study published in the November issue of the urology journal BJUI. The technique is primarily used to treat elderly patients who have complex health issues or decline surgery. But researchers from the Department of Urology at Churchill Hospital, Oxford, UK, say that the results of their study suggest that active surveillance could safely be extended to other selected patients. "The incidence ...

LAST 30 PRESS RELEASES:

New electroenzymatic strategy enables non-natural oxidation reactions

Tunable laser light

Scientists uncover magnetic-field control of ultrafast spin dynamics in 2D ferromagnets

New AI-powered model accurately predicts lung motion with minimal radiation

AI language models show promise in predicting liver cancer treatment outcomes

Tracking insect and bug health in a heartbeat from a digital camera

'Talking fish' not heard by conservation policies, SFU study warns

Thirty years of research shows increased resistance in fungi

Junk food ‘avoids advertising regulation’ with top level UK sports sponsorship

Banking on AI while committed to net zero is ‘magical thinking’, claims report on energy costs of big tech

Ancient river systems reveal Mars was wetter than we thought

Online toolkit to help parents of autistic children improve dental health

The psychological and neurological parallels between sports fandom and religious devotion

Agricultural liming in the US is a large CO2 sink, say researchers

Seaside more likely to make us nostalgic than green places, study finds

Psilocybin delays aging, extends lifespan, Emory study suggests

Buck Institute awarded DARPA contract to pioneer next-gen AI modeling platform

Orange is the new aphrodisiac—for guppies

Murals boost Cincinnati’s vitality, community development

Ad blockers may be showing users more problematic ads, NYU Tandon study finds

Verbal response time reveals hidden sleepiness in older adults

University of Maryland School of Medicine launches groundbreaking study on THC/CBD therapy for dementia-related agitation at end of life

Targeting stem-property and vasculogenic mimicry for sensitizing paclitaxel therapy of triple-negative breast cancer by biomimetic codelivery

SRSF7 promotes pulmonary fibrosis through regulating PKM alternative splicing in lung fibroblasts

Psychological stress-activated NR3C1/NUPR1 axis promotes ovarian tumor metastasis

An anti-complement homogeneous polysaccharide from Houttuynia cordata ameliorates acute pneumonia with H1N1 and MRSA coinfection through rectifying Treg/Th17 imbalance in the gut–lung axis and NLRP3 i

ALKBH3-regulated m1A of ALDOA potentiates glycolysis and doxorubicin resistance of triple negative breast cancer cells

A photodynamic nanohybrid system reverses hypoxia and augment anti-primary and metastatic tumor efficacy of immunotherapy

Acta Pharmaceutica Sinica B Volume 15, Issue 6 Publishes

From injury to agony: Scientists discover brain pathway that turns pain into suffering

[Press-News.org] Novel chewing gum formulation helps prevent motion sickness