Results of the ETAP trial presented at TCT 2012

Nitinol stent performs better than balloon angioplasty alone in treating lesions of the popliteal artery

2012-10-25

(Press-News.org) MIAMI, FL – OCTOBER 24 , 2012 – A study found that a nitinol stent performed better than balloon angioplasty alone in treating blockages of the popliteal artery, which runs through the leg behind the knee. Results of the ETAP trial were presented today at the 24th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium. Sponsored by the Cardiovascular Research Foundation (CRF), TCT is the world's premier educational meeting specializing in interventional cardiovascular medicine.

Due to its location behind the mobile knee joint, it is controversial whether to implant a stent in the popliteal artery for all cases or only for cases in which balloon angioplasty alone results in a suboptimal result. In this study, investigators conducted a prospective, randomized, multi-center trial comparing primary nitinol stent placement to angioplasty alone in patients who had a single, de-novo obstructive lesion in the popliteal artery.

A total of 246 patients from nine centers in Europe were included in this trial. Patients were randomly assigned to either a self-expanding nitinol stent (N=119) or a standard balloon angioplasty procedure (N=127). The primary study endpoint was one-year duplex ultrasound-derived primary patency, defined as freedom from target lesion restenosis without further intervention. Secondary endpoints included target lesion revascularization, secondary patency, changes in Rutherford categories from baseline, and limb salvage rates. X-rays were taken at one year and examined for stent fractures.

The mean lesion length for the PTA group was 43.2 mm compared to 41.3 mm for the stent group. Six patients (2.4%) died during the follow up period. The one-year primary patency rate was significantly higher in the nitinol-stent group (67.4 percent) than in the balloon angioplasty group (44.9 percent, P END

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Results of the TRILOGY ACS Angiographic Cohort presented at TCT 2012

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FFR-guided PCI shows cost-effectiveness when compared to medical therapy for stable CAD

2012-10-25

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Study confirms benefits of transcatheter aortic valve replacement over 3 years

2012-10-25

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2012-10-25

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Scientists target bacterial transfer of resistance genes

2012-10-25

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Research findings breathe new life into lung disease

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Novel radiation therapy QA method: Monte Carlo simulation meets deep learning for fast, accurate epid transmission dose generation

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A new approach to chiral α-amino acid synthesis - photo-driven nitrogen heterocyclic carbene catalyzed highly enantioselective radical α-amino esterification

Results of the ETAP trial presented at TCT 2012

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