(Press-News.org) Laparoscopic adjustable gastric banding – lap banding – is a safe and effective long-term strategy for managing obesity, according to the findings of a landmark 15-year follow-up study of patients treated in Australia.
The follow-up study, the longest and most comprehensive yet reported, was published in the Annals of Surgery, and found a significant number of lap band patients maintained an average weight loss of 26 kilograms for more than a decade after their procedure.
Professor Paul O'Brien and colleagues from the Centre for Obesity Research and Education (CORE) at Monash University in Melbourne analysed the results in 3,227 patients who had gastric banding between 1994, when the procedure was first introduced, and 2011. The patients in the study were averaged at 47 years of age and 78 per cent were women.
Of those patients, 714 had surgery at least 10 years ago and, on average, had maintained a weight loss of 26 kilograms, or almost half of their excess weight.
The weight loss results were similar for the 54 patients in the study who had undergone treatment at least 15 years ago.
"These results show that when you have a significant problem with obesity, a long-term solution is available," Professor O'Brien said.
"This surgery is safe and effective, and it has lasting benefits. Substantial weight loss can change the lives of people who are obese – they can be healthier and live longer."
Professor O'Brien said there were also important ramifications for the control of type 2 diabetes, which was strongly associated with being overweight.
"In obese patients with type 2 diabetes, weight loss after gastric banding can lead to effective control of blood sugar levels without the need for medication in about three-quarters of cases," Professor O'Brien said.
The patients included in the study had followed the rules of their treating team regarding eating, exercise and activity and committed to returning permanently to the aftercare program.
All the surgery was performed by Professor O'Brien, an international pioneer of the technique, and Associate Professor Wendy Brown, President of the Obesity Surgery Society of Australia and New Zealand (OSSANZ).
There were no deaths associated with the surgery or with any later operations that were needed in about half of the patients. About one in 20 patients had the band removed during the study period.
"In treating a chronic disease such as obesity over a lifetime, it is likely that something will need to be corrected at some time in some patients," Professor O'Brien said.
"The study shows a marked reduction of revisional procedures with the introduction of the new version of the Lap-Band 6 years ago. Importantly, those who had revisional surgery lost as much weight in the long term as those who did not need it."
The report also included a comparison of gastric banding – which can be done as a day-surgery procedure – and more invasive types of weight-loss surgery such as gastric bypass that are high risk and require longer hospital stay. The weight loss with gastric banding, and the need for future revisional surgery, was similar to that with gastric bypass.
"Access to weight-loss surgery in Australia remains severely limited for many obese patients as relatively few cases are treated within the public health system. We are working hard to improve access," Professor O'Brien said.
"We have ample evidence that weight-loss surgery is effective, and it is unfair that half of eligible patients cannot be treated, particularly as it has been shown that gastric banding is a highly cost-effective health care measure. The stigma of obesity, and the assumption that it is the person's fault, entrenches discrimination against people who could benefit."
### END
Gastric banding an effective long-term solution to obesity
Landmark study finds
2013-01-17
ELSE PRESS RELEASES FROM THIS DATE:
'Jet-lagged' fruit flies provide clues for body clock synchronisation
2013-01-17
New research led by a team at Queen Mary, University of London, has found evidence of how daily changes in temperature affect the fruit fly's internal clock.
"A wide range of organisms, including insects and humans, have evolved an internal clock to regulate daily patterns of behaviour, such as sleep, appetite, and attention," explains Professor Ralf Stanewsky, senior study author from Queen Mary's School of Biological and Chemical Sciences.
"Research on animal and human clocks shows that they are fine tuned by natural and man-made time cues, for example the daily ...
Genetic admixture in southern Africa
2013-01-17
This press release is available in German.
An international team of researchers from the MPI for Evolutionary Anthropology in Leipzig and the CNRS in Lyon have investigated the maternally inherited mitochondrial DNA of 500 individuals from southern Africa speaking different Khoisan and Bantu languages. Their results demonstrate that Khoisan foragers were genetically more diverse than previously known. Divergent mtDNA lineages from indigenous Khoisan groups were incorporated into the genepool of the immigrating Bantu-speaking agriculturalists through admixture, and have ...
Study of cancer cell metabolism yields new insights on leukemia
2013-01-17
University of Rochester Medical Center scientists have proposed a new reason why acute myeloid leukemia, one of the most aggressive cancers, is so difficult to cure: a subset of cells that drive the disease appear to have a much slower metabolism than most other tumors cells.
The slower metabolism protects leukemia cells in many important ways and allows them to survive better – but the team also found an experimental drug tailored to this unique metabolic status and has begun testing its ability to attack the disease, URMC researchers report in the Jan. 17, 2013, online ...
Bacteria's hidden skill could pave way for stem cell treatments
2013-01-17
A discovery about the way in which bugs spread throughout the body could help to develop stem cell treatments.
Researchers at the University of Edinburgh have found that bacteria are able to change the make-up of supporting cells within the nerve system, called Schwann cells, so that they take on the properties of stem cells.
Because stem cells can develop into any of the different cell types in the body – including liver and brain cells – mimicking this process could aid research into a range of degenerative conditions.
Scientists made the discovery studying ...
RUB researchers find over active enzyme in failing hearts
2013-01-17
A certain enzyme, the CaM kinase II, keeps the cardiac muscle flexible. By transferring phosphate groups to the giant protein titin, it relaxes the muscle cells. This is reported by researchers led by Prof. Dr. Wolfgang Linke of the Institute of Physiology at the Ruhr Universität in the journal Circulation Research. In failing hearts, which don't pump enough blood around the body, the scientists found an overly active CaM kinase II. "The phosphorylation of titin could be a new starting point for the treatment of heart failure" Prof. Linke speculates.
Titin phosphorylation ...
Soft Lego built in the computer
2013-01-17
In developing these novel self-assembling materials, postdoc Barbara Capone has focused on the design of organic and inorganic building blocks, which are robust and can be produced at large scale. Capone has put forward, together with her colleagues at the Universities of Vienna and Mainz, a completely new pathway for the construction of building blocks at the nanoscale.
"Soft Lego" orders in crystal structures
The team of researchers has shown that so-called block copolymer stars – that means polymers that consist of two different blocks and they are chemically ...
Vaginal delivery is the safest option for women with pelvic girdle pain
2013-01-17
Caesarean section increases the risk of persistent pelvic girdle pain after delivery compared with vaginal delivery, according to a new study from the Norwegian Institute of Public Health.
Caesarean section rates are increasing worldwide, and this trend has partly been explained by women's requests for planned caesarean section without a medical reason. Pregnancy-related pelvic girdle pain has been associated with increased preference for caesarean section and with increased planned caesarean section rates.
"Some women with severe pelvic girdle pain might fear that ...
A nano-gear in a nano-motor inside you
2013-01-17
To live is to move. You strike to swat that irritable mosquito, which skilfully evades the hand of death. How did that happen? Who moved your hand, and what saved the mosquito? Enter the Molecular Motors, nanoscale protein-machines in the muscles of your hand and wings of the mosquito. You need these motors to swat mosquitoes, blink your eyes, walk, eat, drink... just name it. Millions of motors tug as a team within your muscles, and you swat the mosquito. This is teamwork at its exquisite best.
Paradoxically, a weak and inefficient motor (called dynein) is the one that ...
A hidden treasure in the Large Magellanic Cloud
2013-01-17
Nearly 200 000 light-years from Earth, the Large Magellanic Cloud, a satellite galaxy of the Milky Way, floats in space, in a long and slow dance around our galaxy. Vast clouds of gas within it slowly collapse to form new stars. In turn, these light up the gas clouds in a riot of colours, visible in this image from the NASA/ESA Hubble Space Telescope.
The Large Magellanic Cloud (LMC) is ablaze with star-forming regions. From the Tarantula Nebula, the brightest stellar nursery in our cosmic neighbourhood, to LHA 120-N 11, part of which is featured in this Hubble image, ...
Potential new treatment for gastrointestinal cancers discovered
2013-01-17
Researchers have identified a complex of proteins that promotes the growth of some types of colon and gastric cancers, and shown that medications that block the function of this complex have the potential to be developed into a new treatment for these diseases.
The complex of proteins, known as mTorc1 (mammalian target of rapamycin complex 1), has previously been implicated in the development of some other cancers but this is the first time it has been shown to promote the growth of colon and gastric cancers that are associated with inflammation.
Dr Stefan Thiem and ...
LAST 30 PRESS RELEASES:
Concerns over maternity provision for pregnant women in UK prisons
UK needs a national strategy to tackle harms of alcohol, argue experts
Aerobic exercise: a powerful ally in the fight against Alzheimer’s
Cambridge leads first phase of governmental project to understand impact of smartphones and social media on young people
AASM Foundation partners with Howard University Medical Alumni Association to provide scholarships
Protective actions need regulatory support to fully defend homeowners and coastal communities, study finds
On-chip light control of semiconductor optoelectronic devices using integrated metasurfaces
America’s political house can become less divided
A common antihistamine shows promise in treating liver complications of a rare disease complication
Trastuzumab emtansine improves long-term survival in HER2 breast cancer
Is eating more red meat bad for your brain?
How does Tourette syndrome differ by sex?
Red meat consumption increases risk of dementia and cognitive decline
Study reveals how sex and racial disparities in weight loss surgery have changed over 20 years
Ultrasound-directed microbubbles could boost immune response against tumours, new Concordia research suggests
In small preliminary study, fearful pet dogs exhibited significantly different microbiomes and metabolic molecules to non-fearful dogs, suggesting the gut-brain axis might be involved in fear behavior
Examination of Large Language Model "red-teaming" defines it as a non-malicious team-effort activity to seek LLMs' limits and identifies 35 different techniques used to test them
Most microplastics in French bottled and tap water are smaller than 20 µm - fine enough to pass into blood and organs, but below the EU-recommended detection limit
A tangled web: Fossil fuel energy, plastics, and agrichemicals discourse on X/Twitter
This fast and agile robotic insect could someday aid in mechanical pollination
Researchers identify novel immune cells that may worsen asthma
Conquest of Asia and Europe by snow leopards during the last Ice Ages uncovered
Researchers make comfortable materials that generate power when worn
Study finding Xenon gas could protect against Alzheimer’s disease leads to start of clinical trial
Protein protects biological nitrogen fixation from oxidative stress
Three-quarters of medical facilities in Mariupol sustained damage during Russia’s siege of 2022
Snow leopard fossils clarify evolutionary history of species
Machine learning outperforms traditional statistical methods in addressing missing data in electronic health records
AI–guided lung ultrasound by nonexperts
Prevalence of and inequities in poor mental health across 3 US surveys
[Press-News.org] Gastric banding an effective long-term solution to obesityLandmark study finds