PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

One in 20 cases of pre-eclampsia may be linked to air pollutant

Ozone exposure during first 3 months of pregnancy may be key

2013-02-07
(Press-News.org) One in every 20 cases of the serious condition of pregnancy, pre-eclampsia, may be linked to increased levels of the air pollutant ozone during the first three months, suggests a large study published in the online journal BMJ Open.

Mothers with asthma may be more vulnerable, the findings indicate.

Pre-eclampsia is characterised by raised blood pressure and the presence of protein in the urine during pregnancy. It can cause serious complications, if left untreated.

The authors base their findings on almost 121,000 singleton births in Greater Stockholm, Sweden, between 1998 and 2006; national data on the prevalence of asthma among the children's mothers; and levels of the air pollutants ozone and vehicle exhaust (nitrogen oxide) in the Stockholm area.

There's a growing body of evidence pointing to a link between air pollution and premature birth, say the authors, while pregnant women with asthma are more likely to have pregnancy complications, including underweight babies and pre-eclampsia.

In all, 4.4% of the pregnancies resulted in a premature birth and the prevalence of pre-eclampsia was 2.7%.

There was no association between exposure to levels of vehicle exhaust and complications of pregnancy, nor were any associations found for any air pollutants and babies that were underweight at birth.

But there did seem to be a link between exposure to ozone levels during the first three months of pregnancy and the risk of premature birth (delivery before 37 weeks) and pre-eclampsia, after adjusting for factors likely to influence the results and seasonal variations in air pollutants, although not spatial variations in exposure.

Each rose by 4% for every 10 ug/m3 rise in ambient ozone during this period, the analysis indicated.

Mothers with asthma were 25% more likely to have a child born prematurely and 10% more likely to have pre-eclampsia than mums without this condition.

Asthma is an inflammatory condition and ozone may therefore have worsened respiratory symptoms and systemic inflammation, so accounting for the larger increase in the risk of premature birth among the mums with asthma, suggest the authors.

But after taking account of the mother's age, previous births, educational attainment, ethnicity, asthma, season and year of conception, the authors calculated that one in every 20 (5%) cases of pre-eclampsia were linked to ozone levels during early pregnancy.

### END


ELSE PRESS RELEASES FROM THIS DATE:

UMass Amherst biostatisticians identify genes linked to heart disease

2013-02-07
AMHERST, Mass. – Recently, large studies have identified some of the genetic basis for important common diseases such as heart disease and diabetes, but most of the genetic contribution to them remains undiscovered. Now researchers at the University of Massachusetts Amherst led by biostatistician Andrea Foulkes have applied sophisticated statistical tools to existing large databases to reveal substantial new information about genes that cause such conditions as high cholesterol linked to heart disease. Foulkes says, "This new approach to data analysis provides opportunities ...

Calcium-binding protein mutations found in heart rhythm disorders

Calcium-binding protein mutations found in heart rhythm disorders
2013-02-07
A team led by Vanderbilt University investigators has discovered two new genes – both coding for the signaling protein calmodulin – associated with severe early-onset disorders of heart rhythm. The findings, reported online Feb. 6 in the journal Circulation, expand the list of culprits that can cause sudden cardiac death and may point to new therapeutic approaches. Nearly two decades of research have identified more than 25 genes in which mutations can increase risk for life-threatening cardiac arrhythmias, said Alfred George, Jr., M.D., chief of the Division of Genetic ...

University of Minnesota researchers discover enzyme behind breast cancer mutations

2013-02-07
MINNEAPOLIS/SAINT PAUL (February 6, 2013) – Researchers at the University of Minnesota have uncovered a human enzyme responsible for causing DNA mutations found in the majority of breast cancers. The discovery of this enzyme – called APOBEC3B – may change the way breast cancer is diagnosed and treated. The findings from a team of researchers led by Reuben Harris, Ph.D., associate professor of biochemistry, molecular biology and biophysics and also a researcher at the Masonic Cancer Center, University of Minnesota, are published in the latest edition of Nature. "We ...

Has the 'Golden Age' of global health funding come to an end?

2013-02-07
WASHINGTON, DC – Despite dire predictions in the wake of the economic crisis, donations to health projects in developing countries appear to be holding steady, according to new research from the Institute for Health Metrics and Evaluation (IHME) at the University of Washington. After reaching a historic high of $28.2 billion in 2010, development assistance for health dropped in 2011 and recovered in 2012. The strong growth in spending from the GAVI Alliance and UNICEF counterbalanced declines in health spending among other donors. The new findings are being announced ...

A massive stellar burst, before the supernova

A massive stellar burst, before the supernova
2013-02-07
An automated supernova hunt is shedding new light on the death sequence of massive stars—specifically, the kind that self-destruct in Type IIn supernova explosions. Digging through the Palomar Transient Factory (PTF) data archive housed at the Department of Energy's National Energy Research Scientific Computing Center (NERSC) at Lawrence Berkeley National Laboratory (Berkeley Lab), astronomers have found the first causal evidence that these massive stars shed huge amounts of material in a "penultimate outburst" before final detonation as supernovae. A focused search ...

Profiting from climate change

2013-02-07
The climate is getting warmer, and sea levels are rising – a threat to island nations. As a group of researchers lead by colleagues from the University of Bonn found out, at the same time, tiny single-cell organisms are spreading rapidly through the world's oceans, where they might be able to mitigate the consequences of climate change. Foraminifera of the variety Amphistegina are stabilizing coastlines and reefs with their calcareous shells. The study's results have now appeared in the international online journal "PLOS ONE." Countless billions of tiny, microscopic ...

Forecasting a supernova explosion

2013-02-07
Pasadena, CA—Type II supernovae are formed when massive stars collapse, initiating giant explosions. It is thought that stars emit a burst of mass as a precursor to the supernova explosion. If this process were better understood, it could be used to predict and study supernova events in their earliest stages. New observations from a team of astronomers including Carnegie's Mansi Kasliwal show a remarkable mass-loss event about a month before the explosion of a type IIn supernova. Their work is published on February 7 in Nature. Several models for the supernova-creation ...

Frequently prescribed drug used in concerning ways with harmful side effects

2013-02-07
TORONTO, Feb. 6, 2013—A popular class of drugs commonly used to treat sleep and mood symptoms continues to be frequently prescribed despite being known to have potentially life-threatening side effects. Previous studies have linked benzodiazepines – a medication class that may be used in chronic obstructive pulmonary disease (COPD) to treat symptoms of insomnia, depression, anxiety and shortness of breath – with adverse outcomes, but until now there has been little information on how frequently it's prescribed or who is using it. COPD, also known as emphysema or chronic ...

11,000 elephants slaughtered in national park

2013-02-07
LIBREVILLE, GABON (February 6, 2013): The Wildlife Conservation Society (WCS) announced today that a national park, once home to Africa's largest forest elephant population, has lost a staggering 11,100 individuals due to poaching for the ivory trade. The shocking figures come from Gabon's Minkebe Park, where recent surveys of areas within the park revealed that two thirds of its elephants have vanished since 2004. The majority of these losses have probably taken place in the last five years. Gabon contains over half of Africa's forest elephants, with a population estimated ...

Children with ACL injuries require special treatment

2013-02-07
Until a child's bones have fully matured (in girls, typically by age 14; in boys, age 16), an injury to the anterior cruciate ligament (ACL)—the primary, stabilizing ligament of the knee joint—requires special consideration, treatment and care to ensure appropriate healing and to prevent long-term complications. According to a review article in the February 2013 issue of the Journal of the American Academy of Orthopaedic Surgeons (JAAOS), ACL injuries once were considered rare in children and adolescents. However, the number of ACL injuries in young athletes is on the ...

LAST 30 PRESS RELEASES:

Are lifetimes of big appliances really shrinking?

Pink skies

Monkeys are world’s best yodellers - new research

Key differences between visual- and memory-led Alzheimer’s discovered

% weight loss targets in obesity management – is this the wrong objective?

An app can change how you see yourself at work

NYC speed cameras take six months to change driver behavior, effects vary by neighborhood, new study reveals

New research shows that propaganda is on the rise in China

Even the richest Americans face shorter lifespans than their European counterparts, study finds

Novel genes linked to rare childhood diarrhea

New computer model reveals how Bronze Age Scandinavians could have crossed the sea

Novel point-of-care technology delivers accurate HIV results in minutes

Researchers reveal key brain differences to explain why Ritalin helps improve focus in some more than others

Study finds nearly five-fold increase in hospitalizations for common cause of stroke

Study reveals how alcohol abuse damages cognition

Medicinal cannabis is linked to long-term benefits in health-related quality of life

Microplastics detected in cat placentas and fetuses during early pregnancy

Ancient amphibians as big as alligators died in mass mortality event in Triassic Wyoming

Scientists uncover the first clear evidence of air sacs in the fossilized bones of alvarezsaurian dinosaurs: the "hollow bones" which help modern day birds to fly

Alcohol makes male flies sexy

TB patients globally often incur "catastrophic costs" of up to $11,329 USD, despite many countries offering free treatment, with predominant drivers of cost being hospitalization and loss of income

Study links teen girls’ screen time to sleep disruptions and depression

Scientists unveil starfish-inspired wearable tech for heart monitoring

Footprints reveal prehistoric Scottish lagoons were stomping grounds for giant Jurassic dinosaurs

AI effectively predicts dementia risk in American Indian/Alaska Native elders

First guideline on newborn screening for cystic fibrosis calls for changes in practice to improve outcomes

Existing international law can help secure peace and security in outer space, study shows

Pinning down the process of West Nile virus transmission

UTA-backed research tackles health challenges across ages

In pancreatic cancer, a race against time

[Press-News.org] One in 20 cases of pre-eclampsia may be linked to air pollutant
Ozone exposure during first 3 months of pregnancy may be key