Testing of study participants who wore head-mounted display systems (Google glasses) found that the glasses created a partial peripheral vision obstruction, according to a study in the November 5 issue of JAMA. Interest in wearable head-mounted display systems for general consumers is increasing, with multiple models in production. However, their effect on vision is largely unknown. Peripheral visual field is a main component of vision and essential for daily activities such as driving, pedestrian safety, and sports. Conventional spectacle frames can reduce visual field, ...

BOSTON – Patients with metastatic melanoma who were treated with ipilimumab, an immune checkpoint blocker, survived 50 percent longer – a median 17.5 months vs. 12.7 months – if they simultaneously received an immune stimulant, according to a study led by Dana-Farber Cancer Institute scientists. Patients in the clinical trial who got the combined therapies also had fewer serious adverse side effects than those who received only ipilimumab, the researchers report in the Journal of the American Medical Association. The group treated with both ipilimumab ...

San Diego — A recently developed Adeno-Associated Virus (AAV)-based medication has the potential to offer substantial protective effects for patients attempting to cease methamphetamine use. This research is being presented at the 2014 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition, the world's largest pharmaceutical sciences meeting, in San Diego, Nov. 2-6. Methamphetamine, commonly referred to as meth, is an addictive substance that can cause brain damage, organ failure, stroke, open sores, rotting teeth, mania, paranoia, ...

San Diego — Scientists have developed a novel topical microbicide loaded with hyaluronic acid (HA) nanofibers that could potentially prevent transmission of the human immunodeficiency virus (HIV) through the vaginal mucosa. This research is being presented at the 2014 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting and Exposition, the world's largest pharmaceutical sciences meeting, in San Diego, Nov. 2-6. HIV is an infectious virus that attacks T lymphocytes, a type of white blood cell that prevents infections and disease. Over time, HIV ...

PHILADELPHIA – An important addition to the "eat less, move more" strategy for weight loss lies in behavioral counseling to achieve these goals. But research on how primary care practitioners can best provide behavioral weight loss counseling to obese patients in their practices — as encouraged by the Centers for Medicare and Medicaid Services (CMS) — remains slim, according to a systematic review of this topic published today in JAMA. The study was led by researchers from the Perelman School of Medicine at the University of Pennsylvania. "After an ...

Washington D.C., November 4, 2014 – A Clinical Perspectives article published in the November 2014 issue of the Journal of the American Academy of Child and Adolescent Psychiatry proposes a tool to empower stakeholders, guide caregivers, and provide a rationale for advocates, when considering the systems of support offered to people with an autism spectrum disorder (ASD). Organizations such as the American Academy of Child and Adolescent Psychiatry, the European Society for Child and Adolescent Psychiatry, the International Association for Child and Adolescent Psychiatry ...

The sun emitted a mid-level solar flare, peaking at 5:40 p.m. EST on Nov. 3, 2014. NASA's Solar Dynamics Observatory, which watches the sun constantly, captured an image of the event. Solar flares are powerful bursts of radiation. Harmful radiation from a flare cannot pass through Earth's atmosphere to physically affect humans on the ground, however -- when intense enough -- they can disturb the atmosphere in the layer where GPS and communications signals travel. To see how this event may affect Earth, please visit NOAA's Space Weather Prediction Center at http://spaceweather.gov, ...

In nature, the right amount of death at the right time might actually help boost a species' population density, according to new research that could help in understanding animal populations, pest control and managing fish and wildlife stocks. In a paper in the journal Trends in Ecology and Evolution, a Princeton University researcher and European colleagues conclude that the kind of positive population effect an overall species experiences from a loss of individuals, or mortality, depends on the size and developmental stage of the creatures that die. If many juveniles ...

Disturbances in the early stages of brain growth, such as preterm birth – when many of the brain's structures have not yet fully developed – appears to affect the brain's neuro-circuitry, which may explain premature babies' higher risk of neurodevelopmental disorders including ADHD and autism spectrum disorder. Researchers led by Natasha Lepore, PhD, of The Saban Research Institute of Children's Hospital Los Angeles, have located significant alterations to specific surface regions of the brain. Described in a study published online this week by the journal ...

WEST LAFAYETTE, Ind. – Researchers are close to commercializing a new type of medical imaging technology that could diagnose cardiovascular disease by measuring ultrasound signals from molecules exposed to a fast-pulsing laser. The system takes precise three-dimensional images of plaques lining arteries and identifies deposits that are likely to rupture and cause heart attacks, said Ji-Xin Cheng (pronounced Jee-Shin), a professor in Purdue University's Weldon School of Biomedical Engineering and Department of Chemistry. The imaging reveals the presence of carbon-hydrogen ...

Hot flushes are one of the most distressing conditions faced by women who have been treated for breast cancer, but they are not being adequately addressed by healthcare professionals and some women consider giving up their post cancer medication to try and stop them, a new study has shown. More than 70 per cent of women who have had breast cancer experience menopausal problems, and hot flushes in particular, which are among the most prevalent and potentially distressing problems following breast cancer treatment. These can also be long lasting, persisting for more than ...

This news release is available in German. "On the one hand, ABC transporters causes diseases such as cystic fibrosis, while on the other hand they are responsible for the immune system recognising infected cells or cancer cells," explains Professor Robert Tampé from the Institute for Biochemistry at the Goethe University. The considerable medical, industrial and economic significance of ABC transporters is also based on the fact that they cause bacteria and other pathogens to become resistant to antibiotics. Likewise, they can help cancer cells to defend themselves ...

CORAL GABLES, Fla. (November 4, 2014) — Think about the way our bodies are assembled during early development and ask: How do neighboring cells know that they are supposed to become a nerve or a bone cell and how do these tissues find the correct place and alignment? Researchers at the University of Miami (UM) are answering these crucial questions. In a new study, UM researchers describe the signaling systems that tissues use to communicate with their surrounding neighbors, at the head-trunk region. Their discovery may have important implications for the treatment ...

Sublingual misoprostol is inferior to intramuscular oxytocin for the prevention of postpartum hemorrhage (PPH) in women undergoing uncomplicated birth at a regional hospital in Uganda, according to trial results published in PLOS Medicine. The randomized non-inferiority trial, conducted by Esther Cathyln Atukunda at the Mbarara University of Science and Technology, Uganda, and colleagues, showed that PPH incidence in the misoprostol arm exceeded that in the oxytocin arm by 11.2% (95% confidence interval 6.44%-16.1%). PPH is responsible for 25–30% of maternal deaths. ...

In an analysis of the 2003–2010 MarketScan US database, Rakesh Bhattacharjee and coauthors (University of Chicago, Chicago, Illinois) compared hospital admissions and prescriptions for children with asthma who underwent adenotonsillectomy before and after surgery to determine whether their asthma control improved (based on ICD-9-CM and CPT codes, as well as drug prescriptions) in the year after compared with the year before surgery. They also compared the children with children with asthma who did not undergo adenotonsillectomy who were the same age and sex and lived ...

Surgical removal of the tonsils and adenoids in children suffering from sleep apnea is associated with decreased asthma severity, according to the first large study of the connection, published in the journal PLOS Medicine. Researchers from the University of Chicago found that in the first year after the operation, children who had the surgery had a 30 percent reduction in acute asthma exacerbations and a 38 percent decrease in acute status asthmaticus—a medical emergency. They also found pediatric patients who received the surgery had a 36 percent reduction ...

Asthma may be more harmful than was previously thought, according to UCLA researchers who found that genetic damage is present in circulating, or peripheral, blood. Doctors previously thought that the genetic damage it caused was limited to the lungs. In the study, researchers looked for the overexpression of a cytokine called interleukin 13 (IL-13), which is known to mediate inflammation, a critical problem for people with asthma. The study, which was conducted in an animal model that mimicked human asthma, was the first to assess the role of IL-13 in genetic damage ...

RENO, Nev. – The puzzle pieces of tectonic plates that make up the outer layer of the earth are not rigid and don't fit together as nicely as we were taught in high school. A study published in the journal Geology by Corné Kreemer, an associate professor at the University of Nevada, Reno, and his colleague Richard Gordon of Rice University, quantifies deformation of the Pacific plate and challenges the central approximation of the plate tectonic paradigm that plates are rigid. Using large-scale numerical modeling as well as GPS velocities from the largest ...

WASHINGTON, D.C., November 4, 2014--If you took the junk from the back of your closet and combined it with the dirty laundry already on your floor, you would have an even bigger mess. While this principle will likely always hold true for our bedrooms, it turns out that in certain situations, combining messes can actually reduce the disorder of the whole. An international team of researchers from Slovenia and Iran has identified a set of conditions in which adding disorder to a system makes it more orderly. This behavior is known as antifragility, a concept introduced recently ...

A newly published research study examining only marketing directed at children on the interior and exterior of fast food restaurants has found that the majority of black, middle-income and rural communities are disproportionately exposed to such marketing tactics. Authored by Arizona State University researcher Punam Ohri-Vachaspati and her colleagues, the study is the first to examine the use of child-directed marketing on the interior and exterior of fast food restaurants and its relationship to demographics. It adds to a substantial body of literature on the effects ...

PITTSBURGH—It's commonly believed that creativity is a process that involves connecting ideas and building on the past to create something new. But is it better to "think outside the box," using unrelated concepts to get the creative juices flowing, or to build on something more closely related to the problem one is trying to solve? In a paper newly published in Design Studies, recent University of Pittsburgh graduate Joel Chan and his mentor Christian Schunn of Pitt's Learning Research and Development Center, along with Carnegie Mellon University's Steven Dow, ...

NASA's Aqua satellite passed over Vance on Nov. 3 as it started moving in a northeasterly direction toward the northwestern coast of Mexico. On Nov. 4, a Tropical Storm Watch was in effect from Mazatlan northward to Topolobampo, Mexico. Hurricane Vance is forecast to make landfall in northwestern mainland Mexico on Nov. 5. On Nov. 3 at 20:50 UTC (3:50 p.m. EST) the Moderate Resolution Imaging Spectroradiometer or MODIS instrument that flies aboard NASA's Aqua satellite captured a visible image of Hurricane Vance off Mexico's west coast. The eastern quadrant of the storm ...

New research provides details on how gut bacteria turn a nutrient found in red meat into metabolites that increase the risk of developing heart disease. Publishing in the November 4th issue of the Cell Press journal Cell Metabolism, the findings may lead to new strategies for safeguarding individuals' cardiovascular health. Previous research led by Dr. Stanley Hazen, of Lerner Research Institute and the Miller Family Heart and Vascular Institute at Cleveland Clinic, revealed a pathway by which red meat can promote atherosclerosis, or hardening of the arteries. Essentially, ...

ATLANTA—A new statistical test that looks at the patterns of high-frequency network activity flow from brain signals can help doctors pinpoint the exact location of seizures occurring in the brain and make surgery more effective, according to researchers at Georgia State University and Emory University School of Medicine. The findings are published in the journal Epilepsia. Emory researchers Dr. Charles Epstein, Dr. Robert Gross and Dr. Jon Willie; Dr. Bhim Adhikari, a post doctoral researcher at Georgia State, and Dr. Mukesh Dhamala, an associate professor of ...

ROCHESTER, Minn. — In an international study, Mayo Clinic researchers and collaborators have identified genetic markers that may help in identifying individuals who could benefit from the alcoholism treatment drug acamprosate. The findings, published in the journal Translational Psychiatry, show that patients carrying these genetic variants have longer periods of abstinence during the first three months of acamprosate treatment. Acamprosate is a commonly prescribed drug used to aid patients in recovery from alcoholism. Mayo researchers studied the association between ...