Biochemists at the Ruhr-Universität Bochum have gained new insights into the generation and maintenance of circadian rhythms. They demonstrated that the Ras protein is important for setting the phase of such a circadian clock, as its activity determines the period length of the rhythm. Ras is also contributing to induce phase-shifts in circadian rhythms in response to external time cues such as light. The team headed by Prof Dr Rolf Heumann published their results in the magazine "Molecular Neurobiology". Ras activity varies throughout the day The circadian clock ...

Absence, it seems, really does make the heart grow fonder. That's according to research conducted by UC Santa Barbara anthropologists, who found that levels of the "love" hormone oxytocin increases among Tsimane men when they come home to their families after a day of hunting. The researchers also found that the increase in oxytocin was greater for those men who were absent longer, and it positively correlated with changes in testosterone. Their findings are published in the Royal Society journal Biology Letters. The Tsimane are an indigenous population of forager-farmers ...

For many, Facebook connects friends, family, and others with common interests. Despite the popularity of social networking sites like Facebook, scientists are only beginning to learn how they affect human interaction. In a recent study published by the journal Social Science & Medicine, Dartmouth researchers examined nearly 9,000 Facebook conversations to better understand how people seek and receive support on social networking sites. "Among the many Facebook conversations that were mostly casual, we noticed more serious exchanges among people who mentioned a major ...

As one of the strongest cyclones every recorded in the South Pacific Ocean, Cyclone Pam devastated the island archipelago of Vanuatu. The Global Precipitation Measurement or GPM core observatory provided data on rain rates throughout the storm. At the end of Pam's life on March 17, NASA's RapidScat provided a look at the winds of the waning storm. As the cyclone bore down on Vanuatu's central islands on the afternoon (local time) of March 13, 2015, Pam's maximum sustained winds were estimated to have increased to 270 kph (~167 mph) by the U.S. Joint Typhoon Warning Center ...

New research shows that courtship rituals evolve very fast in cichlid fish in Lake Malawi. Whenever species evolve to feed at different depths, their courtship evolves as well. In the shallows where the light is good, males build sand castles to attract females. Males of deep-dwelling species dig less elaborate pits and compensate with longer swimming displays. The results are published in the open-access journal Frontiers in Ecology and Evolution. "Lake Malawi cichlids are famous for the diversity and fast evolution of their feeding habits, body form, and sex determination ...

Men and women who adapt their daily diet to meet current UK dietary guidelines could reduce their risk of a heart attack or a stroke by up to a third, according to a new study by King's College London. The study, published in the American Journal of Clinical Nutrition, recruited healthy middle-aged and older men and women to compare the effects on risk factors for cardiovascular disease (CVD) of following a diet based on UK health guidelines compared with a traditional British diet. The predicted risk of CVD over the next 10 years for the participants was estimated to ...

In diseases such as asthma and chronic obstructive pulmonary disease (COPD), the body produces too much mucus, making breathing difficult. New research from Washington University School of Medicine in St. Louis provides clues to potentially counteract inappropriate mucus production. "The new study lays the groundwork for developing treatments for diseases such as asthma, COPD, cystic fibrosis and even certain cancers," said senior author Thomas J. Brett, PhD, assistant professor of medicine. "It also solves a 20-year mystery about the role of a protein that has long been ...

Researchers at the San Diego Supercomputer Center (SDSC) and the Moores Cancer Center at the University of California, San Diego, have described for the first time the molecular mechanism of cancer development caused by well-known "resistance" mutations in the gene called epidermal growth factor receptor (EGFR). While these mutations were known for quite a long time, the question as to why they cause cancer or make some drugs ineffective was still not answered. The study, called "Molecular Determinants of Drug-Specific Sensitivity for Epidermal Growth Factor Receptor ...

Tropical Cyclone Bavi weakened to a depression and NASA's RapidScat instrument measured its waning winds from space. On March 17 the RapidScat instrument aboard the International Space Station (ISS) measured Bavi's surface winds from 01:28 to 3:01 UTC. RapidScat data showed surface winds were strongest winds in the northwestern quadrant. Sustained winds were near 17 m/s (38 mph/61 kph) and weaker around the rest of the storm. On March 18 at 0000 UTC (March 17 at 8 p.m. EDT), the Joint Typhoon Warning Center noted that Bavi's maximum sustained winds dropped to 25 knots ...

Cambridge, Mass. - March 17, 2015 - The velvet worm is a slow-moving, unassuming creature. With its soft body, probing antennae, and stubby legs, it looks like a slug on stilts as it creeps along damp logs in tropical climates. But it has a secret weapon. In the dark of night, when an unsuspecting cricket or termite crosses its path, the worm unleashes an instantaneous torrent of slime. Two fine jets of the gluey substance spray out of openings on its head, oscillating in all directions to cast a sticky net that entraps prey and stops it in its tracks. Captivated, ...

While unconscious race and social class biases were present in most trauma and acute-care clinicians surveyed about patient care management in a series of clinical vignettes, those biases were not associated with clinical decisions, according to a report published online by JAMA Surgery. Disparities in the quality of care received by minority patients have been reported for decades across multiple conditions, types of care and institutions, according to the study background. Adil H. Haider, M.D., M.P.H., of Brigham and Women's Hospital, Boston, conducted a web-based survey ...

ANN ARBOR, Mich. - Drugs aimed at quelling the behavior problems of dementia patients may also hasten their deaths more than previously realized, a new study finds. The research adds more troubling evidence to the case against antipsychotic drugs as a treatment for the delusions, hallucinations, agitation and aggression that many people with Alzheimer's disease and other dementias experience. In the new issue of the journal JAMA Psychiatry, researchers report findings from nearly 91,000 American veterans over the age of 65 with dementia. Data from each patient who ...

TORONTO (March 18, 2015) - People with a severe form of schizophrenia have major differences in their brain networks compared to others with schizophrenia, bipolar disorder and healthy individuals, a new study from the Centre for Addiction and Mental Health (CAMH) shows. The study, which used a novel approach to map brain networks, was led by researchers at the Campbell Family Mental Health Research Institute at CAMH and published in this week's JAMA Psychiatry. "Finding ways to help this particular group of people with schizophrenia is a priority as recovery is ...

COLLEGE STATION - A ground-breaking Texas A&M AgriLife Research-led study on corn has identified useful gene variations for yield increases, drought tolerance and aflatoxin resistance that could make a real difference to Texas producers in the years to come, according to researchers. The study, titled "Genome Wide Association Study for Drought, Aflatoxin Resistance, and Important Agronomic Traits of Maize Hybrids in the Sub-Tropics" was recently published in PLOS ONE, an international, peer-reviewed, open-access, online publication. The study included the growing years ...

From computers, tablets, and smartphones to cars, homes, and public transportation, our world is more digitally connected every day. The technology required to support the exchange of massive quantities of data is critical. That's why scientists and engineers are intent on developing faster computing units capable of supporting much larger amounts of data transfer and data processing. A new study published in Nature Photonics by Tel Aviv University researchers finds that new optical materials could serve as the nuts and bolts of future ultra-high-speed optical computing ...

TORONTO, March 18, 2015--Researchers have defined a new bodily process in mice that may explain why blood oxygen levels are lower for patients with cystic fibrosis when they get a lung infection. "Infected areas of the lung are not as capable as healthy tissue at adding oxygen to the bloodstream, but no one has shown why this is the case," said Dr. Wolfgang Kuebler, a scientist in the Keenan Research Centre for Biomedical Science of St. Michael's Hospital. "We've shown that the protein produced by a gene known as CFTR is required to direct blood flow away from infected ...

This news release is available in Spanish. Using discarded electronic boards, the UPV/EHU researcher Andoni Salbidegoitia has, in collaboration with international researchers, developed a system for obtaining clean hydrogen that can be used as fuel. The researchers have already registered the patent of the process in Japan. The Chemical Technologies for Environmental Sustainability (TQSA) Group of the Department of Chemical Engineering of the UPV/EHU's Faculty of Science and Technology is aiming to make use of discarded plastic as effectively as possible from the ...

Bats are not as stereotyped when they hunt as previously believed. New research shows that these flying mammals are capable of making ultra-fast decisions about how to attack their prey - or maybe even call off the attack. It takes only milliseconds. Bats use echolocation for orientation. They emit ultrasonic sounds, which hit potential prey nearby, sending an echo back to the bat. From this echo the bat can define where the prey is and attack it. A new study has examined how hunting bats react when approaching their prey. The study concludes that bats are capable of ...

Imagine a loved relative suffering from cancer - and you could not afford a treatment because the drugs are too expensive. The Austrian Centre of Industrial Biotechnology (acib) developed a method with the power to reduce production costs of highly valued drugs significantly. Without antibodies we would be at the mercy of pathogens or cancer cells. Therapeutic antibodies are used as passive vaccines, for cancer therapy or for controlling autoimmune diseases such as multiple sclerosis. According to "bccresearch.com" the global market for antibody drugs was worth nearly ...

Researchers have fine-tuned a technique for coating gold nanorods with silica shells, allowing engineers to create large quantities of the nanorods and giving them more control over the thickness of the shell. Gold nanorods are being investigated for use in a wide variety of biomedical applications, and this advance paves the way for more stable gold nanorods and for chemically functionalizing the surface of the shells. Gold nanorods have a lot of potential applications, because they have a surface plasmon resonance - meaning they can absorb and scatter light. And by ...

This news release is available in Spanish. Alzheimer's disease is the most significant cause of dementia in the elderly: it affects over 35 million people worldwide. It is reckoned that Alzheimer's could reach epidemic proportions in developed countries unless therapies to cure or prevent it are obtained. Studies conducted so far reveal that the therapies are more effective when they are applied before the brain has become severely damaged. What is more, the spotting of early phases of the disease may help to develop new treatments. Right now, to make a clinical diagnosis ...

A new microarray-based tool, called VaginArray, offers the potential to provide a fast, reliable and low-cost assessment of vaginal health and diagnoses of infections. The research is published ahead of print March 2, in Antimicrobial Agents and Chemotherapy, a journal of the American Society for Microbiology. The VaginArray has 17 probe sets, each one specific for one of the most representative bacterial species inhabiting the vaginal ecosystem, including those associated with both healthy and unhealthy conditions. Each probe set is designed to be complementary to the ...

ALBUQUERQUE, N.M. -- Researchers at Sandia National Laboratories' Z machine have helped untangle a long-standing mystery of astrophysics: why iron is found spattered throughout Earth's mantle, the roughly 2,000-mile thick region between Earth's core and its crust. At first blush, it seemed more reasonable that iron arriving from collisions between Earth and planetesimals -- ranging from several meters to hundreds of kilometers in diameter -- during Earth's late formative stages should have powered bullet-like directly to Earth's core, where so much iron already exists. A ...

This news release is available in French. Basic research on blood pressure has led researchers from Inserm (Inserm Unit 1138, "Cordeliers Research Centre") to obtain unexpected results: drugs used to treat hypertension (high blood pressure) reduce side effects from corticosteroid-based creams used to treat certain skin diseases. This work is published in the Journal of Investigative Dermatology. Corticosteroid-based dermatological creams are indicated for the symptomatic treatment of inflammatory skin conditions, such as atopic dermatitis and psoriasis, for example. ...

Uplift associated with the Great Rift Valley of East Africa and the environmental changes it produced have puzzled scientists for decades because the timing and starting elevation have been poorly constrained. Now paleontologists have tapped a fossil from the most precisely dated beaked whale in the world -- and the only stranded whale ever found so far inland on the African continent -- to pinpoint for the first time a date when East Africa's mysterious elevation began. The 17 million-year-old fossil is from the beaked Ziphiidae whale family. It was discovered 740 ...