A new study led by Adelaide researchers has estimated, for the first time, the rates of evolution during the "Cambrian explosion" when most modern animal groups appeared between 540 and 520 million years ago. The findings, published online today in the journal Current Biology, resolve "Darwin's dilemma": the sudden appearance of a plethora of modern animal groups in the fossil record during the early Cambrian period. "The abrupt appearance of dozens of animal groups during this time is arguably the most important evolutionary event after the origin of life," says lead ...

One of the most important and massive parts of the galaxy is the galactic bulge. This huge central cloud of about 10 000 million stars spans thousands of light-years, but its structure and origin were not well understood. Unfortunately, from our vantage point from within the galactic disc, the view of this central region — at about 27 000 light-years' distance — is heavily obscured by dense clouds of gas and dust. Astronomers can only obtain a good view of the bulge by observing longer wavelength light, such as infrared radiation, which can penetrate the dust clouds. Earlier ...

Washington, D.C.—Hydrocarbons from the Earth make up the oil and gas that heat our homes and fuel our cars. The study of the various phases of molecules formed from carbon and hydrogen under high pressures and temperatures, like those found in the Earth's interior, helps scientists understand the chemical processes occurring deep within planets, including Earth. New research from a team led by Carnegie's Alexander Goncharov hones in on the hydrocarbon methane (CH4), which is one of the most abundant molecules in the universe. Despite its ubiquity, methane's behavior ...

Researchers at the Pediatric Diabetes Research Center (PDRC) at the University of California, San Diego School of Medicine have shown that the pancreatic protein Nkx6.1 – a beta-cell enriched transcription factor – is essential to maintaining the functional state of beta cells. Type 2 diabetes is characterized by impaired insulin secretion by pancreatic beta cells in response to a rise in blood glucose levels. The study, published in the September 26 edition of Cell Reports, shows that loss of NKx6.1 in mice caused rapid onset diabetes. UC San Diego scientists – ...

CAMBRIDGE, MA -- Like a pea going through a straw, tiny molecules can pass through microscopic cylinders known as nanotubes. This could potentially be used to select molecules according to size — for example, to purify water by allowing water molecules to pass through while blocking salt or other substances. Now, researchers at MIT, Seoul University in Korea and Ursinus College in Pennsylvania have found that such tubes are more selective than had been thought: Molecules of a precise size can zip through five times faster than those that are a bit smaller or larger. The ...

(RENO): The Arctic is the most rapidly warming region of the globe, but warming has not been uniform and the drivers behind this warming not fully understood even during the 20th century. A new study authored by Canadian and American investigators and published in Scientific Reports, a primary research publication from the publishers of Nature, suggests that both anthropogenic and natural factors – specifically sulphate aerosols from industrial activity and volcanic emissions, in addition to greenhouse gas releases from fossil fuel burning – account for Arctic surface ...

Basic fibroblast growth factor exhibits a high affinity for heparin. Heparin combined with basic fibroblast growth factor significantly contributes to the differentiation of umbilical cord mesenchymal stem cells into motor neurons. Xueyuan Liu and colleagues from Liaoning Medical University found that the third passage of umbilical cord mesenchymal stem cells induced with heparin and basic fibroblast growth factor exhibited neuronal morphology, and Hb9 expression and acetylcholine levels increased following induction with heparin combined with basic fibroblast growth factor. ...

Sevoflurane belongs to volatile anesthetics, and preconditioning with sevoflurane has been shown to exert protective effects against ischemic injury in the brain. But the mechanism is unclear. Although studies have shown the neuroprotective effects of sevoflurane preconditioning in the transient cerebral ischemia model, its effect in the permanent focal cerebral ischemia model remains unclear. Dr. Qiu and colleagues from Sichuan University found that 60-minute sevoflurane preconditioning significantly reduced the infarct volume and the number of apoptotic cells in the ischemic ...

Since Moffat and Ramsden for the first time discovered the possibility of the auditory system in humans in 1977, over the last two decades, great progress has been made in physiopathological research on neurosensory hearing loss. Jørgensen and Mathiesen were the first authors to note the capacity for regeneration of the normal vestibular epithelium in adult Australian parrots. Later, Roberson et al studied the normal vestibular epithelium of 12-day-old white Leghorn chicks using tritiated thymidine and bromodeoxyuridine. Francisco Santaolalla and colleagues from Basurto ...

PULLMAN, Wash. – Two nearly identical softballs, both approved for league play, can have dramatically different effects when smacked into a player's head. Those are the findings from a study conducted by Professor Lloyd Smith in the School of Mechanical and Materials Engineering and project engineer Derek Nevins that they will present at the Asia Pacific Congress on Sports Technology later this month in Hong Kong. Their work was published in the journal, Procedia Engineering. Smith's group developed a unique model of a softball that they electronically throw at a virtual ...

Researchers at ETH Zurich have developed an internal combustion engine that emits less than half the CO2 compared to a regular engine without compromising performance. This corresponds to fuel consumption of less than 2.4l per 100km. This natural gas-diesel hybrid engine is based on a system of sophisticated control engineering. The global energy markets are changing. New extraction methods are tapping into oilfields and natural gas deposits that have been inaccessible until now. The US, for example, is able to cover up to 83% of its total energy needs today; the government ...

Higher costs would in turn increase the threshold for decision-makers to start the transition to a low-carbon economy. Thus, to keep climate targets within reach it seems to be most relevant to not further postpone mitigation, the researchers conclude. "The transitional economic repercussions that would result if the switch towards a climate-friendly economy is delayed, are comparable to the costs of the financial crisis the world just experienced," lead-author Gunnar Luderer says. The later climate policy implementation starts, the faster – hence the more expensive – ...

The birth of stars is an event that eludes intuitive understanding. It is the collapse of dense molecular clouds under their own weight that offers the best sites of star formation. Now, Pralay Kumar Karmakar from the Department of Physics at Tezpur University, Assam province, India, and his colleague have proposed a new model for investigating molecular cloud fluctuations at sites of star formation and thus are able to study their pulsational dynamics, in a paper published in EPJ D. Dust molecular clouds are a type of astrophysical plasmas, which are composed of a primordial ...

The DiMelli (Diabetes Mellitus Incidence Cohort Registry) study examines the frequency and characteristics of diabetes phenotypes in children and young adults below the age of 20. The study was commissioned to investigate the increasing incidence of diabetes mellitus, particularly in childhood and early adulthood. The project is funded by the German Center for Diabetes Research (DZD). Bioprobe measurements were performed centrally by the Central Medical Laboratory (LMZ) at the Helmholtz Zentrum München (HMGU) so as to guarantee the high quality and comparability of laboratory ...

Using large and frequent doses of the pain-killer codeine may actually produce heightened sensitivity to pain, without the same level of relief offered by morphine, according to new research from the University of Adelaide. Researchers in the Discipline of Pharmacology have conducted what is believed to be the world's first experimental study comparing the pain relieving and pain worsening effects of both codeine and morphine. The University's Professor Paul Rolan, who is also a headache specialist at the Royal Adelaide Hospital, says codeine has been widely used as ...

Designers of social robots, take note. Bring your dog to the lab next time you test a prototype, and watch how your pet interacts with it. You might just learn a thing or two that could help you fine-tune future designs. So says Gabriella Lakatos of the Hungarian Academy of Science and Eötvös Loránd University, lead author of a study¹ published in Springer's journal Animal Cognition that found that man's best friend reacts sociably to robots that behave socially towards them, even if the devices look nothing like a human. This animal behavior study tested the reaction ...

Just days before a team of researchers from Woods Hole Oceanographic Institution (WHOI) and National Taiwan University set out to conduct fieldwork in the East China Sea, Typhoon Morakot—one of the most destructive storms ever to hit Taiwan—made landfall on the island, causing widespread damage and drastically altering the flow of water along the nearby continental shelf. The typhoon, which struck in Aug. 2009, caused catastrophic damage in Taiwan, killing several hundred people and dropping up to 2 meters of rain in just 5 days in the mountains. In their work to understand ...

RESEARCH CONCLUSIONS: New genetic research led by the Genographic Project consortium shows a distinctive ancestry for the Uros populations of Peru and Bolivia that predates the arrival of the Spanish conquistadores and may date back to the earliest settlement of the Altiplano, or high plain, of the central Andes some 3,700 years ago. Despite the fact that the Uros today share many lineages with the surrounding Andean populations, they have maintained their own divergent genetic ancestry. WHO ARE THE UROS?: The Uros are a self-identified ethnic group, about 2,000 ...

A study of patients infected with acute hepatitis C virus (HCV) infection found that women had higher rates of spontaneous viral clearance—undetectable levels of the virus without initiating drug therapy. Findings published in Hepatology, a journal of the American Association for the Study of Liver Diseases, indicate that the gene IL28B (rs12979860) and HCV genotype 1 are also independent predictors of spontaneous HCV clearance. In 2011, there were 1,229 cases of acute HCV reported to the Centers for Disease Control and Infection (CDC), which represents a 44% increase ...

PITTSBURGH—Analyses of Twitter feeds have been used to track flu epidemics, predict stock market changes and do political polling, but now that the National Football League season is underway, the natural question is: Can Twitter help beat the spread on NFL games? The answer, say computer scientists at Carnegie Mellon University, is yes. Or, at least it can help a little bit at certain times during the season. They will report their findings Sept. 27 at the Machine Learning and Data Mining for Sports Analytics conference in Prague, Czech Republic. The study began as ...

Hubble previously observed this cluster back in 2002. However, this new image combines visible and infrared data from Hubble's Advanced Camera for Surveys (ACS) to reveal this patch of sky in greater detail than ever before, with a combined total exposure time of over 34 hours. These new, deeper, observations were taken in order to explore the globular clusters within Abell 1689 [1]. This new study has shown that Abell 1689 hosts the largest population of globular clusters ever found. While our galaxy, the Milky Way, is only home to around 150 of these old clumps of stars, ...

If the violins were taken away from the musicians performing Beethoven's 9th symphony, the resulting composition would sound very different. If the violins were left on stage but the violinists were removed, the same mutant version of the symphony would be heard. But what if it ended up sounding like "Hey Jude" instead? This sort of surprise is what scientists from the Virginia Tech Carilion Research Institute had during what they assumed to be a routine experiment in neurodevelopment. Previous studies had shown that the glycoprotein Reelin is crucial to developing ...

ST. PETERSBURG, Fla. (Sept. 12, 2013) — Acidification of the Arctic Ocean is occurring faster than projected according to new findings published in the journal PLoS One. The increase in rate is being blamed on rapidly melting sea ice, a process that may have important consequences for health of the Arctic ecosystem. Ocean acidification is the process by which pH levels of seawater decrease due to greater amounts of carbon dioxide being absorbed by the oceans from the atmosphere. Currently oceans absorb about one-fourth of the greenhouse gas. Lower pH levels make water ...

MANHATTAN, KAN. -- A Kansas State University microbiologist has found a breakthrough herbal medicine treatment for a common human fungal pathogen that lives in almost 80 percent of people. Govindsamy Vediyappan, assistant professor of biology, noticed that diabetic people in developing countries use a medicinal herb called Gymnema slyvestre to help control sugar levels. He decided to study the microbiological use of Gymnema slyvestre -- a tropical vine plant found in India, China and Australia -- to see if it could treat a common human fungal pathogen called Candida albicans. The ...

Philadelphia, PA—One way to study criminal behavior and predict a criminal's next move is by analyzing his or her movement. Several mathematical models have addressed this in detail, in particular, the UCLA "burglary hotspot" model, also the topic of a previous Nugget published by the Society for Industrial and Applied Mathematics (SIAM). In a paper published last month in the SIAM Journal on Applied Mathematics, authors Sorathan Chaturapruek, Jonah Breslau, Daniel Yazdi, Theodore Kolokolnikov, and Scott McCalla propose a mathematical model that analyzes criminal movement ...