Cannabis use tied to head and neck cancer
2024-08-08
LOS ANGELES — A study from the USC Head and Neck Center, part of Keck Medicine of USC and the USC Caruso Department of Otolaryngology – Head and Neck Surgery, suggests that cannabis, the most commonly used illicit substance worldwide, is associated with an increased occurrence of head and neck cancer.
A large, multicenter study published in JAMA Otolaryngology – Head & Neck Surgery revealed that adults with cannabis dependence, known as cannabis use disorder, are 3.5 to 5 times more likely to develop head and neck cancer than those who do not use the substance.
“This ...
Kamikaze drones built at KTU in Lithuania are sent to Ukraine
2024-08-08
KTU M-Lab, the Centre of Experimental and Prototyping Laboratories at Kaunas University of Technology, Lithuania, in cooperation with the company Nando Droid, is constructing first-person view (FPV) kamikaze drones, which are being sent to Ukraine and used in the war field. These drones are fitted with explosives that are activated when they hit an obstacle.
Kaunas University of Technology students assembling the drones say that they are built to have a long flight range and the ability to carry a large payload.
“The war in Ukraine is already being called a drone war. Without them, this war would be unimaginable. It saves many lives,” says the representative ...
Scalable production of next-generation high-performance printable solar cells
2024-08-08
As climate change continues to advance, the need for low-carbon, clean energy alternatives has become more urgent than ever. A research team at City University of Hong Kong (CityUHK) has developed a new generation of printable perovskite solar cells that offer higher efficiency and stability, lower cost and scalability, with a minimal carbon footprint. With funding support from the inaugural Research, Academic and Industry Sectors One-plus Scheme (RAISe+ Scheme) of the Innovation and Technology Commission of the HKSAR government, the team aims to establish ...
Tsinghua University Press and ResearchGate announce first Journal Home partnership from China
2024-08-08
Beijing (China) and Berlin (Germany) August 8, 2024 – Tsinghua University Press (TUP), the leading university press in China, and ResearchGate, the professional network for researchers, are delighted to announce a new Journal Home partnership that aims to increase the readership and visibility of TUP’s open access research. The agreement is the first of its kind with a Chinese publisher.
The agreement covers five fully open-access journals published by TUP through their platform, SciOpen, including research published in Artificial Intelligence, Energy, Materials, and Construction. In ...
Promoting healthy teen romantic relationships to reduce risk of unintended pregnancies and sexually transmitted infections
2024-08-08
INDIANAPOLIS -- Romantic relationships play an important part in adolescent development. Most young people have had at least one romantic relationship by middle adolescence (ages 14 to17). However, successful promotion of healthy sexual behavior to reduce risk of unintended pregnancies and sexually transmitted infections in this teen population has proven difficult.
Regenstrief Institute and Indiana University Research Scientist Arthur Owora, PhD, MPH, a quantitative epidemiologist and applied biostatistician, is the first author of a new multi-site ...
Recurrent wheezing in children linked to 'silent' viral infections
2024-08-08
Nearly a quarter of children with recurrent wheezing have “silent” lung infections that would be better treated with antiviral medications than commonly prescribed steroids that can carry lifelong side effects, new research from the University of Virginia School of Medicine reveals.
Pediatric pulmonologist W. Gerald Teague, MD, was inspired to investigate after noting large numbers of children with stubborn wheezing cases referred from community providers and through the UVA Health Emergency Department. Knowing that rhinoviruses – the main cause of the common cold – can trigger wheezing episodes, Teague wanted to see if there ...
South Africa’s controversial lion farming industry is fueling the illegal international trade in big cat bones
2024-08-08
A new research paper published in the scientific journal Nature Conservation has uncovered concerning activities within South Africa's captive lion industry, shedding light on the urgent need for comprehensive governmental action.
The study by World Animal Protection, conducted through direct interviews with workers at two closed-access lion facilities in South Africa’s North West Province, reveals disturbing practices. These include:
The use of legal activities such as commercial captive lion breeding and canned hunting to mask involvement in the illegal international trade of lion and tiger bones.
Animal welfare violations including ...
Children can inherit early aging symptoms from parents who abuse alcohol, researchers find
2024-08-08
Researchers at the Texas A&M School of Veterinary Medicine and Biomedical Sciences (VMBS) have discovered that parents who struggle with alcohol use disorders can pass along symptoms of early aging to their children, affecting them well into adulthood.
These accelerated aging effects — including high cholesterol, heart problems, arthritis, and early onset dementia — can be passed down from either mom or dad individually, but they become worse when both parents have an issue with alcohol abuse, especially in male offspring.
“Scientists have wondered what causes children who grow up in homes where there is alcohol ...
Distinct pattern in protein production can predict severe side effects from skin cancer treatment
2024-08-08
An activity pattern in certain genes responsible for building proteins known as spleen tyrosine kinases can predict which melanoma patients are likely to have severe side effects from immunotherapy designed to treat the most deadly skin cancer, a new study shows.
Led by researchers at NYU Langone Health and its Perlmutter Cancer Center, the latest experiments focused on checkpoint inhibitors, drugs that have in the last decade become a mainstay of treating melanoma. This form of skin cancer kills nearly 10,000 Americans annually.
The drugs work by blocking molecules ...
Lens-free fluorescence instrument detects deadly microorganisms in drinking water
2024-08-08
WASHINGTON — Researchers have shown that a fluorescence detection system that doesn’t contain any lenses can provide highly sensitive detection of deadly microorganisms in drinking water. With further development, the new approach could provide a low-cost and easy-to-use way to monitor water quality in resource-limited settings such as developing countries or areas affected by disasters. It could also be useful when water safety results are needed quickly, such as for swimming events, a concern highlighted during the Paris Olympics.
“In developing countries, unsafe water sources ...
Individualized cancer therapy demonstrates safety and sustained immune responses
2024-08-08
For decades, researchers have worked to develop therapies that can prime the immune system to recognize and attack proteins on the surface of tumor cells. However, success has been limited due to the technological challenge of engineering therapies that provide specific enough “training” to the immune system to identify a given patient’s neoantigens. Now, investigators from Massachusetts General Hospital (MGH), a founding member of the Mass General Brigham healthcare system, have evaluated an ...
Eating disorder risks elevated among women with PCOS
2024-08-08
WASHINGTON—Women with the common reproductive and metabolic condition polycystic ovary syndrome (PCOS) face a greater risk of developing bulimia, binge eating disorder and disordered eating, according to new research published in The Journal of Clinical Endocrinology & Metabolism.
PCOS affects roughly one in eight women. Women who have the condition face an increased risk of developing metabolic problems such as diabetes, reproductive issues such as infertility, and psychological issues including anxiety and depression.
Women are diagnosed when they have at least two of the three ...
The first universal principles for designing solid-state batteries developed by Korean researchers
2024-08-08
A Korean research team has presented the first universal design principles for solid-state batteries, signaling a paradigm shift in battery design research that previously lacked standard benchmarks.
Dr. Jinsoo Kim from the Ulsan Advanced Energy Technology R&D Center of the Korea Institute of Energy Research (KIER) and Professor Sung-Kyun Jung's research team from the Ulsan National Institute of Science and Technology (UNIST) have jointly developed a design principles and a versatile design toolkit for implementing high-energy-density solid-state batteries and have completed performance verification.
With ...
Alcohol use in older adults doubles risk of brain bleeds from falls
2024-08-08
Nationally, falls remain the leading cause of both fatal and non-fatal injuries in older adults and are the leading cause of traumatic brain injury. In 2021, falls led to the deaths of 36,500 older adults in the United States and 3,805 older Floridians. While some studies have hypothesized that alcohol use contributed to these outcomes, there are few studies which have examined this issue.
As such, little is known about the association between the frequency of alcohol use and the severity of injuries sustained after a fall in older adults. A study by Florida Atlantic University’s Schmidt College of Medicine and collaborators, is one of the first to examine the relationship ...
Insilico Medicine received IND approval and orphan drug designation from FDA for ISM6331, an AI-designed TEAD inhibitor targeting solid tumors and mesothelioma
2024-08-08
CAMBRIDGE, Mass., Aug 8, 2024 --- Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven biotechnology company, today announced ISM6331, potential best-in-class pan-TEAD inhibitor, has received the U.S. Food and Drug Administration (FDA) Investigational New Drug (IND) clearance for the treatment of mesothelioma, following the grant of Orphan Drug Designation (ODD) in June 2024. It brings the total number of IND-approved molecules of Insilico to nine.
Mesothelioma is a type of cancer that affects the mesothelium, a thin layer of tissue that covers most of the ...
Are birds flying atoms?
2024-08-08
A crowd or a flock of birds have different characteristics from those of atoms in a material, but when it comes to collective movement, the differences matter less than we might think. We can try to predict the behavior of humans, birds, or cells based on the same principles we use for particles. This is the finding of a new study published in the Journal of Statistical Mechanics: Theory and Experiment, JSTAT, conducted by an international team that includes the collaboration of MIT in Boston and CNRS in France. The study, based on the physics ...
New study is helping to understand and achieve species elements in the Kunming–Montreal Global Biodiversity Framework
2024-08-08
Experts provide clarity on key terms for urgent species recovery actions to support the implementation of the Global Biodiversity Framework.
The Kunming-Montreal Global Biodiversity Framework (KMGBF) is a landmark agreement ratified in 2022 by Parties to the Convention on Biological Diversity that outlines ambitious goals to combat biodiversity decline.
The Framework states outcomes for species to be achieved by 2050 in Goal A and establishes a range of targets to reduce pressures on biodiversity and halt biodiversity loss ...
Unlocking the secrets of salt stress tolerance in wild tomatoes
2024-08-08
As our climate changes and soil salinity increases in many agricultural areas, finding crops that can thrive in these challenging conditions is crucial. Cultivated tomatoes, while delicious, often struggle in salty soils. Their wild cousins, however, have evolved to survive in diverse and often harsh environments. A recent study delved into the genetic treasure trove of wild tomatoes to uncover secrets of salt tolerance that could be used to develop resilient crop varieties.
A team of researchers focused on Solanum pimpinellifolium, the closest wild relative of our beloved cultivated tomato. These tiny, ...
Detecting climate change using aerosols
2024-08-08
Climate change is one of the most significant environmental challenges of present times, leading to extreme weather events, including droughts, forest fires, and floods. The primary driver for climate change is the release of greenhouse gases into the atmosphere due to human activities, which trap heat and raise Earth’s temperature. Aerosols (such as particulate matter, PM2.5) not only affect public health but also influence the Earth's climate by absorbing and scattering sunlight and altering cloud properties. Although future climate change predictions are being reported, it is possible that the impacts of climate change could be more severe than predicted. ...
Exploring the impact of attentional uniqueness and attentional allocation on firm growth
2024-08-08
According to the attention-based view, a firm’s actions and growth performance are directly influenced by its attentional allocation to specific issues. The consequences of organizational attention are reflected in the firm’s strategic decision-making and adaptability. However, existing literature is limited in its exploration of how a firm’s attentional uniqueness impacts its behavior and performance. Notably, attentional uniqueness refers to how the firm’s attentional allocation diverges from competitors in the same industry.
To address the above-mentioned knowledge gap, Associate Professor Takumi ...
Breakthrough in molecular control: new bioinspired double helix with switchable chirality
2024-08-08
The deoxyribonucleic acid or DNA, the molecular system that carries the genetic information of living organisms, can transcribe and amplify information using its two helical strands. Creating such artificial molecular systems that match or surpass DNA in functionality is of great interest to scientists. Double-helical foldamers are one such molecular system.
Helical foldamers are a class of artificial molecules that fold into well-defined helical structures like helices found in proteins and nucleic acids. They have garnered considerable attention as stimuli-responsive switchable molecules, tuneable chiral materials, and cooperative supramolecular systems due to their chiral and ...
Saliva indicates severity of recurrent respiratory infections in children
2024-08-08
A saliva test can more accurately indicate the severity of recurrent respiratory infections in children than the standard blood test. If saliva contains too few broadly protective antibodies, a child is more likely to suffer from pneumonia episodes. This is reported by researchers from Radboudumc Amalia Children's Hospital and UMC Utrecht Wilhelmina Children's Hospital in the European Respiratory Journal. Saliva testing provides valuable information for treatment and is more comfortable for children.
About ...
Short, intense bursts of exercise more effective after stroke than steady, moderate exercise
2024-08-08
Research Highlights:
Researchers found repeated one-minute bursts of high-intensity interval training were more effective than traditional, moderate continuous exercise for improving the body’s aerobic fitness after a stroke.
Fitness level improvements doubled in participants in the high-intensity interval training group compared to those in the moderate intensity exercise group.
Researchers found the level of fitness changes in the high intensity interval training group were associated with improved survival and lower risk of stroke-related ...
Imaging technique uncovers protein abnormality in motor neurone disease
2024-08-08
Pathological abnormalities associated with motor neurone disease have been identified using a new technique developed at the University of Birmingham.
The method will help scientists better understand the changes in the brain that lead to motor neurone disease (MND) and could eventually yield insights that will help with the development of new treatments. The abnormalities were identified in a collaboration between the University of Birmingham and the University of Sheffield and published today [8 Aug] in Nature Communications.
Motor neurone disease, also known ...
Scientists unravel how the BCG vaccine leads to the destruction of bladder cancer cells
2024-08-08
Using zebrafish “Avatars”, an animal model developed by the Cancer Development and Innate Immune Evasion lab at the Champalimaud Foundation (CF), led by Rita Fior, Mayra Martínez-López – a former PhD student at the lab now working at the Universidad de las Américas in Quito, Ecuador – and colleagues studied the initial steps of the Bacillus Calmette-Guérin (BCG) vaccine’s action on bladder cancer cells. Their results, which are published today (August 1, 2024) in the journal Disease Models and Mechanisms, show that macrophages – the first line of ...
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