SEATTLE – A study led by researchers at Fred Hutchinson Cancer Research Center has found that a next-generation, high-speed DNA-decoding technology called high-throughput sequencing can detect the earliest signs of potential relapse in nearly twice the number of leukemia patients as compared to flow cytometry, the current gold standard for detecting minimal residual disease. The results of the study, led by Hutchinson Center computational biologist Harlan Robins, Ph.D., are reported in the May 16 issue of Science Translational Medicine. "The ability to predict disease ...

While the mobile community continues to grow, Dr. Hahn, dentist in Kentwood, MI, is happy to offer an advanced mobile website to better meet the needs of patients who are constantly on the go. Today, in a technologically advanced society, more and more people are utilizing their smart phones and tablet devices for their daily needs. From ordering food to looking up important information, patients use their smart phones and tablet devices on a daily basis. By offering a mobile website, Dr. Hahn, dentist in Kentwood, enhances his patients' ability to receive important ...

Common variants of the ApoE gene are strongly associated with the risk of developing late-onset Alzheimer's disease, but the gene's role in the disease has been unclear. Now, researchers funded by the National Institutes of Health have found that in mice, having the most risky variant of ApoE damages the blood vessels that feed the brain. The researchers found that the high-risk variant, ApoE4, triggers an inflammatory reaction that weakens the blood-brain barrier, a network of cells and other components that lines brain's brain vessels. Normally, this barrier allows ...

Dr. Greg Herzler, Saginaw Township dentist, appreciates his patients' feedback about his practice. By leaving reviews, patients help Dr. Herzler to improve his practice to better serve his patients. Patients can visit the practice's website for instant access to available links to leave their feedback on the review site of their choice. "I always look forward to hearing from my patients about their experience with my office. By leaving reviews, my patients allow me to constantly improve my practice and the way we serve our patients. I hope to continue to provide ...

The movement patterns of critically endangered leatherback turtles vary greatly depending on whether the animals live in the North Atlantic or the Eastern Pacific, with implications for feeding behavior and population recovery, according to research published May 16 in the open access journal PLoS ONE. The authors, led by Helen Bailey of the University of Maryland Center for Environmental Science, found that turtles in the Atlantic had two travel modes, low and high speed, associated with foraging and transit, respectively. The Pacific turtles, on the other hand, only ...

Multidrug-resistant pathogens are becoming more frequent, and the few "last resort" treatments available for infections with these bacteria have also shown an increase in use in recent years, according to a study published May 16 in the open access journal PLoS ONE. The authors, led by Makoto Jones of the Veterans Affairs Salt Lake City Health Care System, investigated the use of two such antibiotics, polymyxins and tigecycline, in 127 Veterans Affairs medical centers between 2005 and 2010. They found that the overall use of these treatments was quite low, but that it ...

Leading dentist in Flushing and Flint, MI, Dr. Scott Pelok, is pleased to introduce the practice's newest piece of dental technology- the Galileos 3D cone beam scanner. The new dental diagnostic system is helping the practice continue to bring patients the most efficient, comfortable and effective dentistry possible. The new Galileos 3D diagnostic system allows Dr. Pelok and his team to create a precise 3D image of a patient's entire jaw in a matter of seconds- in significantly less time than traditional x-rays. The Galileos advanced technology allows patients to be ...

In 1848, railroad worker Phineas Gage survived a severe brain injury when a tamping rod shot through his skull, resulting in significant behavioral changes. In a new study, reported May 16 in the open access journal PLoS ONE, researchers have used CT images of his skull in conjunction with MRI and connectomic brain imaging data of living subjects to reconstruct the injury and investigate which regions of the brain were affected to result in the behavioral changes. The research team, led by John Van Horn of University of California Los Angeles, found that considerable ...

DURHAM, N.C. – What can a fish tell us about human brain development? Researchers at Duke University Medical Center transplanted a set of human genes into a zebrafish and then used it to identify genes responsible for head size at birth. Researchers at Duke University Medical Center transplanted a set of human genes into a zebrafish and then used it to identify genes responsible for head size at birth. Head size in human babies is a feature that is related to autism, a condition that recent figures have shown to be more common than previously reported, 1 in 88 children ...

Boston, MA ─ A new study from Harvard School of Public Health (HSPH) and the World Health Organization (WHO) found that a simple checklist-based childbirth safety program dramatically improved adherence to essential childbirth care practices at a pilot hospital in south India. Of 29 practices measured, 28 were improved after adoption of the checklist and overall adherence to essential practices was 150% better after the checklist was introduced. "This is a significant step forward because it provides hope that use of this simple, low-cost tool can help birth attendants ...

PHILADELPHIA – A team from the Perelman School of Medicine and the Abramson Family Cancer Research Institute at the University of Pennsylvania found that the FDA-approved drug daclizumab improved the survival of breast cancer patients taking a cancer vaccine by 30 percent, compared to those patients not taking daclizumab. This proof-of-concept study is published this week in Science Translational Medicine. Senior authors of the study are Robert H. Vonderheide, MD, DPhil, associate professor of Medicine, and James Riley, PhD, associate professor of Microbiology. The team ...

With two convenient office locations, Dr. Ed Davis, San Antonio podiatrist, offers exceptional foot and ankle health care for his patients from surrounding communities. To further expand on his treatment and care offered at both locations, Dr. Davis also provides patients with an advanced website that is home to a wealth of valuable podiatric educational tools. "I want my patients to fully understand the importance of their foot and ankle health care and offering valuable educational tools on my website help me to do just that. We are always on our feet, but we ...

The Diagnostic and Statistical Manual of Mental Disorders (DSM), long the master reference work in psychiatry, is seriously flawed and needs radical change from its current "field guide" form, according to an essay by two Johns Hopkins psychiatrists published in the May 17 issue of the New England Journal of Medicine. "A generation ago it served useful purposes, but now it needs clear alterations," says Paul R. McHugh, M.D., a professor of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine and co-author of the paper with Phillip R. Slavney, ...

MINNEAPOLIS – A new study suggests that head impacts experienced during contact sports such as football and hockey may worsen some college athletes' ability to acquire new information. The research is published in the May 16, 2012, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study involved college athletes at three Division I schools and compared 214 athletes in contact sports to 45 athletes in non-contact sports such as track, crew and Nordic skiing at the beginning and at the end of their seasons. The contact sport athletes ...

With five convenient office locations, Drs. Gary Grippo and Sean Lazarus, Branford podiatrists, of Center Podiatry, Advanced FootCare Center strive to continue to provide their patients with advanced communication efforts. In order to do so, Drs. Grippo and Lazarus are happy to announce the launch of their new social network - Facebook and Twitter. "We are committed to providing our patients with safe, comfortable and convenient podiatric health care. In order to do so we currently have five office locations for our patients to easily visit. In addition to our ...

LGL leukemia is a relatively rare, malignant blood disease of the mature T-cells and, in many cases, it is related to autoimmune diseases such as rheumatoid arthritis. The pathogenetic mechanism of the disease has been unknown and it has previously been unclear if the disease is an overreaction of the normal defense system or a malignant hematological disease. One of the key symptoms of LGL disease is a low count of white blood cells (neutrophils), which may predispose the patients to life-threatening infections. It was discovered that patients suffering from LGL leukemia ...

Palliative care for cancer patients in the UK is well established – but the situation is starkly different for those suffering from heart failure. A recent service evaluation led by the University of Hull and Hull York Medical School (HYMS) shows this doesn't have to be the case – particularly if clinicians have the courage to talk about death with their patients. The study – published today (May 17) in the British Journal of Cardiology – describes data from two areas in Yorkshire where palliative care and heart failure services are fully integrated – Bradford & Airedale ...

Since graduating dental school in 1991, Dr. Paresh Naran, Raleigh dentist, has completed over 800 continuing education credits. By completing extensive continuing education hours, Dr. Naran helps to ensure his patients are receiving the most up-to-date dental care possible. "With dentistry constantly advancing with new procedures and technology, it is important that I remain up-to-date with these changes. In order to do so, I maintain continuing education courses each year, and have been doing so since I graduated from dental school," said Dr. Paresh Naran, ...

Suicides by psychiatric in-patients have fallen to a new low, research published today (Thursday) has found. The study by the University of Manchester's National Confidential Inquiry into Suicide and Homicide by People with Mental Illness, one of very few to look at trends over time, shows the rate of suicide among psychiatric in-patients fell by between 29% and 31% between 1997 and 2008 with nearly 100 fewer deaths per year. The falls were seen across most groups of patients with the biggest falls in young patients and those with schizophrenia. On wards, deaths by ...

CORAL GABLES, FL (May 14, 2012) -- A new University of Miami (UM) study shows that one in three children who have an older sibling with an Autism Related Disorder (ASD) fall into a group characterized by higher levels of autism-related behaviors or lower levels of developmental progress. The study will be presented at the International Meeting for Autism Research (IMFAR) in May, 2012. ASDs are developmental conditions characterized by problems with social interaction and communication. Previously, an international consortium of researchers found that almost one in five ...

Visiting Dr. Charles Middleton, Fort Wayne dentist, at Middleton Family Dentistry for regular checkups and cleanings can help prevent many dental problems as well as to help patients maintain optimal oral health. In order to provide his patients with the best care possible, Dr. Middleton offers advice for his patients by sharing dental tips for when to visit Middleton Family Dentistry for treatment. "Regular dentists to Middleton Family Dentistry allow us to find early signs of disease. By visiting our office at least twice a year, we can treat problems while they ...

A new paper published online in The Lancet challenges the assumption that raising a person's HDL — the so-called "good cholesterol" — will necessarily lower the risk of a heart attack. The new research underscores the value of using genetic approaches to test biological hypotheses about human disease prior to developing specific drugs. A team led by researchers from the Broad Institute and Massachusetts General Hospital (MGH) explored naturally occurring genetic variations in humans to test the connection between HDL levels and heart attack. By studying the genes of roughly ...

The U.S. Food and Drug Administration (FDA) generally approves drug therapies faster and earlier than its counterparts in Canada and Europe, according to a new study by Yale School of Medicine researchers. The study counters perceptions that the drug approval process in the United States is especially slow. Led by second-year medical student Nicholas Downing and senior author Joseph S. Ross, M.D., assistant professor of internal medicine at Yale School of Medicine, the study will be published May 16 online by the New England Journal of Medicine. Regulatory review represents ...

While maintaining quality dental health care for her patients of all ages at White Eagle Family Dentistry, Dr. Joon Sun, Naperville cosmetic dentist, maintains continuing education courses. By continuing her education, Dr. Sun ensures that she is providing her patients with the most up-to-date dental technology and treatments. Dr. Joon Sun, family dentist in Naperville, is passionate about her work and her patients, which is further seen through her continuing education. She continually attends education seminars to stay abreast of the latest techniques and technology ...

A team of investigators have shown evidence of chronic traumatic encephalopathy (CTE) in brain tissue from blast-exposed military service personnel. Laboratory experiments conducted at Boston University, New York Medical College (NYMC) and the Veterans Affairs Boston Healthcare System demonstrated that exposure to a single blast equivalent to a typical improvised explosive device (IED) results in CTE and long-term brain impairments that accompany the disease. They also found that the blast wind, not the shock wave, from the IED blast leads to traumatic brain injury (TBI) ...