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Reikartz Hotels & Resorts Invite to Ethno&Jazz Festival in Spring Lviv

2011-04-03
Creative association Dzyga and Ukrainian hotel chain Reikartz Hotels & Resorts present the 9th International Ethno & Jazz Festival "Flugery Lvova with Reikartz". The festival continues the series of cultural events in Lviv held with support of Reikartz Hotels & Resorts. This year "Flugery Lvova with Reikartz", already a musical trademark of Lviv, will be held from April 30th to May 2nd. All the festival concerts except for famous Waking up with the Mertvyi Piven Show are free for every visitor. The scene of the festival will traditionally have its unique location ...

Cover 4 Fleet Insurance Show You How To Set Up A H.A.D. (Heightened Awareness Driving) Policy

2011-04-03
Follow the Cover 4 Fleet Insurance simple instructions outlined here to increase the safety awareness amongst the fleet drivers and management. Although the Heightened Awareness Driving (H.A.D.) has been developed by this UK fleet insurance company, it is not for insurance purposes, but to help you strengthen the fleet risk management and safety policies. Making Your Heightened Awareness Driving Fleet Policy The Health and Safety Executives guidelines are that in every organisation that employs six people or more should possess a written policy regarding safety when ...

International Marine Transport and MOL Tankship Management Agree on Merger

2011-04-03
Mitsui O.S.K. Lines, Ltd. (MOL; President: Koichi Muto) today announced that two of its group companies—International Marine Transport Co., Ltd. and MOL Tankship Management Ltd. - have agreed to merge effective April 1, 2011, and continue and expand their business as MOL Ocean Expert Co., Ltd. The merger plan was approved by the shareholders' meetings of both companies. The details are as follows: 1. Outline of new company Name: MOL Ocean Expert Co., Ltd. Address: 2-1-1 Toranomon, Minato-ku, Tokyo Paid-in-capital: 100 million President: Hiroki Kasai No. of employees: ...

Family Friendly CPD and TeaFor Me, Say 6000 Vets!

2011-04-03
This March 'The Webinar Vet' celebrates its first year of delivering high quality CPD,with an incredible 6000 delegates attending the company's webinars in the last 12 months. And to encourage even more to sample the delights of webinars, The Webinar Vet is offering 100 vets the opportunity to sign up to Individual Gold membership at a saving of GBP50* a month. The company was founded by vet Anthony Chadwick last year, as a remedy to late nights spent trying to fulfill his CPD requirement at the end of a tiring day in practice, "It's been just great to find out that ...

eSilverBullet Acquires a Website Builder

2011-04-03
eSilverBullet, Inc., a Utah-based technology company that helps companies succeed in eCommerce, announced today it had acquired Magniphy, a platform used for building web sites. Magniphy is a software tool that eliminates the complexity of creating an online store front. It provides a simple interface for choosing a domain name, picking a website template, uploading products and using an integrated shopping cart with merchant account. It allows individuals and budding businesses to grow an idea into a fully functioning online storefront in minutes or hours, rather than ...

Get-It-Straight Orthodontists in Rochester, Pittsford, and Macedon NY Now Offer Virtually Invisible DAMON CLEAR Braces

Get-It-Straight Orthodontists in Rochester, Pittsford, and Macedon NY Now Offer Virtually Invisible DAMON CLEAR Braces
2011-04-03
In the Rochester NY area, residents who want straight teeth and a fuller, more beautiful smile without the awkward look and discomfort of traditional braces no longer have to settle for metal brackets or clear aligners. Get-It-Straight Orthodontics with three locations in Pittsford NY, Rochester NY, and Macedon NY in Gananda, is now offering DAMON CLEAR, a virtually invisible braces system that delivers fast, comfortable treatment without the "metal mouth" look to accommodate today's image-conscious adults and teens. Traditional braces require elastic ties to hold wires ...

Pacific Highlands Ranch in North San Diego County Meets Needs of Growing Family; Manzanita Trail by Pardee Homes was the Right Choice for the Glenn Family

Pacific Highlands Ranch in North San Diego County Meets Needs of Growing Family; Manzanita Trail by Pardee Homes was the Right Choice for the Glenn Family
2011-04-03
The Glenn family is happily settled into their second new home at Pacific Highlands Ranch with the recent purchase of Plan 4 home at Manzanita Trail. This former Scripps Ranch family made the move to the coastal-close master planned community several years ago where they bought at Pardee Homes' Portico. As their needs grew, and their two sons did too, they were ready for a move to Manzanita Trail, also built by Pardee Homes. "We wanted a bigger house and a yard, so we were first on the waiting list when Manzanita Trail opened for sale two years ago," said Annie Glenn, ...

The AACR increases focus on clinical trials

2011-04-03
ORLANDO, Fla. — The American Association for Cancer Research Annual Meeting continues to be a showcase for the most cutting edge science in cancer, and this year's meeting, held here April 2-6, will include an increased focus on clinical trials that will impact patient care. Daniel D. Von Hoff, M.D., physician-in-chief and distinguished professor at the Translational Genomics Research Institute (TGen), professor of medicine at the Mayo Clinic, and chief scientific officer at Scottsdale Healthcare and U.S. Oncology Research, will host a press conference on Saturday, April ...

New inhibitor prevented lesions, reduced tumor size in basal cell cancer

2011-04-03
ORLANDO, Fla. — A new hedgehog pathway inhibitor demonstrated efficacy in preventing and treating basal cell cancer among patients with basal cell nevus syndrome, a rare inheritable disease, according to Phase II data presented at the AACR 102nd Annual Meeting 2011, held April 2-6. In 1996, Ervin Epstein Jr., M.D., senior scientist at Children's Hospital of Oakland Research Institute, and colleagues identified the site of the mutation that causes basal cell nevus syndrome: the PTCH gene, which encodes a primary inhibitor of the hedgehog signaling pathway. This pathway ...

BATTLE researchers identify new biomarkers for EGFR inhibition

2011-04-03
ORLANDO, Fla. — Scientists are continuing their work on the Biomarker-integrated Approaches of Targeted Therapy for Lung Cancer Elimination trial — known more commonly as the BATTLE trial — and presented updated results at the AACR 102nd Annual Meeting 2011, held here April 2-6. John Heymach, M.D., Ph.D., associate professor of thoracic, head and neck medical oncology at The University of Texas MD Anderson Cancer Center, said this update details the "discovery phase" of the ongoing program. "Last year, we presented results on pre-specified markers to determine how ...

Ringling College of Art and Design Annual Fundraiser Receives Major Contribution from Park West Gallery

2011-04-03
Ringling College of Art and Design in Sarasota, FL held its 14th annual scholarship fundraiser event, "An Evening at the Avant-Garde: Once Upon a Time," on Saturday, March 26, 2011. As a major sponsor of this year's event, Park West Gallery, now in its 42nd year as a leading fine art gallery, will help "make dreams come true" for Ringling students through its generous contribution to the school. Park West Gallery is fulfilling its mission to promote art enrichment by providing Ringling with artwork for their Avant-Garde fundraiser. An eclectic mix of works by renowned ...

Sainsbury's Travel Money Launches Online Service

2011-04-03
Sainsbury's Travel Money today launches an online service that will allow customers to 'click and collect' their holiday money. The 0% commission on foreign currency, which offers competitive exchange rates, will give customers the choice of having their money delivered to home or collecting it from one of the 117 Sainsbury's Travel Money bureaux across the UK. Sainsbury's shoppers who use the online Travel Money service will also benefit from an introductory offer of 1,000 Nectar points for every GBP500 of foreign currency they purchase. Furthermore, customers who choose ...

Get Help if Mounting Bills are Making it Difficult to Keep Up

2011-04-03
The IVA Advisory Centre has encouraged struggling consumers to take advantage of the wide range of help available if they feel mounting bills are affecting their ability to keep up with their other essential costs. The comments come in response to a spate of price rises for consumers in recent months. Towards the end of last year, many saw their energy bills increase sharply - with further increases anticipated for this year by some analysts - and at the end of February, water industry regulator Ofwat announced that water bills would increase by an average of 4.6% from ...

Combining MEK and PI3K inhibitors appears encouraging in a safety study with early signs of anti-tumor activity

2011-04-03
ORLANDO, Fla. — The combination of two compounds that inhibit two of the most frequently mutated cancer pathways is showing promise in an ongoing Phase I trial, according to data presented at the AACR 102nd Annual Meeting 2011, held here April 2-6. The research, presented by Johanna Bendell, M.D., tests a combination of GDC-0973, which inhibits MEK1/2 and GDC-0941, which inhibits PI3K. Bendell, director of Gastrointestinal Oncology Research and associate director of the drug development unit at the Sarah Cannon Research Institute in Nashville, said the RAS/RAF/MEK and ...

LateRooms.com - Tennis Stars to Compete at Mutua Madrid Open

2011-04-03
Many of the world's top tennis players will head to Spain for the Mutua Madrid Open, which begins on Friday April 29th. The ATP World Tour Masters 1000 event is due to run until Sunday May 8th at the Spanish capital's new Caja Magica stadium, also known as the Magic Box. As the world's highest ranking tennis competition below the Grand Slams, the Masters Series is known for exciting events in which the sport's finest players can battle to become world number one. The Mutua Madrid Open has been going as a men's tournament since 1990, but received a major overhaul ...

Chronic stress of cancer causes accelerated telomere shortening

2011-04-03
ORLANDO, Fla. — Results of a study presented at the AACR 102nd Annual Meeting 2011, held here April 2-6, lend credence to the idea that improving quality of life affects stress-related biological markers and possibly the health of people with cancer. Researchers know that telomeres shorten and deteriorate with aging, but they are learning that stress also affects telomere length. "We are trying to understand the interconnections between the mind and the body; that is, how does the diagnosis and treatment of cancer impact patients not only psychologically, but also physiologically ...

Target for lung cancer chemoprevention identified

2011-04-03
ORLANDO, Fla. — Scientists have identified a biomarker for measuring the success of lung cancer chemoprevention, an emerging frontier in the fight against this disease that has long been stymied by a lack of measureable outcomes. These study results were presented at the AACR 102nd Annual Meeting 2011, held April 2-6. Paul Bunn, M.D., executive director of the International Association for the Study of Lung Cancer and the James Dudley endowed professor of lung cancer research at the University of Colorado Cancer Center at the University of Colorado School of Medicine, ...

LateRooms.com - Organist Donald MacKenzie to Play in Pembrokeshire

2011-04-03
Donald MacKenzie, an organist who specialises in accompanying silent films, is due to perform at the Torch Theatre next month. The Ayrshire-born musician is the house organist at the famous Odeon Cinema in London's Leicester Square, where he has been playing for various events since 1992. Mackenzie has broadcast from the Odeon on several BBC radio stations, as well as playing for the Queen at numerous royal film performances. His show at the Pembrokeshire venue will take place at 19:30 BST on Tuesday April 26th, when members of the audience are set to enjoy his ...

Genetic variation linked to longer telomeres and lower risk of bladder cancer

2011-04-03
ORLANDO, Fla. — Using new genetic information, scientists have linked a commonly found human genetic variant with both longer telomeres and reduced risk of bladder cancer, according to findings presented at the AACR 102nd Annual Meeting 2011, held April 2-6, and simultaneously published in Cancer Prevention Research, a journal of the American Association for Cancer Research. Jian Gu, Ph.D., assistant professor of epidemiology at The University of Texas MD Anderson Cancer Center, said the single-nucleotide polymorphism (SNP) rs398652 on 14q21 was linked to both longer ...

DNA of 50 breast cancer patients decoded

DNA of 50 breast cancer patients decoded
2011-04-03
In the single largest cancer genomics investigation reported to date, scientists have sequenced the whole genomes of tumors from 50 breast cancer patients and compared them to the matched DNA of the same patients' healthy cells. This comparison allowed researchers to find mutations that only occurred in the cancer cells. They uncovered incredible complexity in the cancer genomes, but also got a glimpse of new routes toward personalized medicine. The work was presented at the American Association for Cancer Research 102nd Annual Meeting 2011. In all, the tumors had more ...

LateRooms.com - Top Musicians Get Ready for Cheltenham Jazz Festival

2011-04-03
A diverse line-up of musicians and plenty of family entertainment lies in store at this year's Cheltenham Jazz Festival. Jamie Cullum has been appointed guest director for the event, which will take over the Gloucestershire town from Wednesday April 27th to Monday May 2nd. The jazz-pop pianist is an enthusiastic supporter of the festival and is due to perform live in Cheltenham on May 1st, although tickets for that show are already scarce. However, the programme includes plenty of other highlights for contemporary jazz fans, including several of Cullum's favourite ...

LateRooms.com - Sade to Perform at Prague's O2 Arena

2011-04-03
Sade's performance in Prague later this year is set to provide a real treat for fans of sophisticated R'n'B and laidback soul. The award-winning British band, named after lead vocalist Sade Adu, will return to the Czech capital for the first time in many years on Saturday May 14th. Having ended a prolonged hiatus with last year's critically acclaimed new album Soldier of Love, the group are heading back out on the road for a series of shows across Europe. Fans of Sade, who have built up a devoted base of followers since the release of their debut LP Diamond Life ...

Entry inhibitors show promise as drugs with new MOA for treatment of HBV and HDV infection

2011-04-03
Berlin, Germany, Saturday 02 April 2011: Promising new viral hepatitis data presented today at the International Liver CongressTM show that entry inhibitors --a new mechanism of action for drugs to treat viral hepatitis -- could provide the first new hepatitis B and hepatitis D treatments for many years.1,2 Most current approved therapies directly target viral replication (e.g. nucleotide/side analogues), and can lead to the development of viral resistance or viral rebound after the end of treatment. Entry inhibitors prevent the virus from entering the cell and forming ...

In vitro infection and replication of hepatitis E virus in human hepatocytes

2011-04-03
Groundbreaking data presented today demonstrates, for the first time, in vitro infection and replication of swine hepatitis E virus (HEV) in human hepatocytes.1 This study also verifies that HEV is a zoonosis (infectious disease that can be transmitted from animals to humans), which has been suggested for a long time. HEV is a major cause of epidemic and acute sporadic hepatitis in many developing countries. It is also endemic in many industrialized countries, including the United States, European countries and Japan. Four major genotypes (genotypes 1-4) of HEV have ...

LateRooms.com - See John Godber's Bouncers in the Lake District

2011-04-03
The Theatre by the Lake is preparing to stage a new production of Bouncers, the acclaimed play by John Godber. People in the audience at the Keswick venue will be drawn into the world of Lucky Eric, Judd, Ralph and Les - the group of doormen who keep a watchful eye on proceedings at the Mr Cinders nightclub. The bouncers observe a number of colourful characters as they go about their business, with the action set against a backdrop of flashing disco lights and pulsating music. First staged in 1977, the drama is one of the West Yorkshire-born playwright's most enduringly ...
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