Bournemouth is getting ready to welcome Mick Jones and his band Big Audio Dynamite for a show at the O2 Academy next month. The former Clash guitarist and singer reunited with the group earlier this year after more than a decade apart and they have announced a series of dates around the world. Big Audio Dynamite will play the Old Fire Station on Thursday June 23rd, the day before they go on stage at Glastonbury Festival. The south coast gig is likely to act as a warm-up concert for the event, so attendees will effectively be able to enjoy a set that would otherwise ...

Simon Evans will take the stage at the Rosehill Theatre on Friday May 27th, sharing his hilarious Fridge Magnet tour with a Lake District audience. His contribution to last year's Edinburgh Fringe Festival was highly acclaimed and he is also one of the stars on Michael McIntyre's Comedy Roadshow. Evans's brand of comedy is outrageously dry and his wit has seen him recruited to collaborate with some of the top comics in the UK, including Dara O'Briain and Lee Mack. But his appeal stretches beyond our borders, having enjoyed sell-out gigs all over the world. In ...

The O2 in London will host a special performance by acclaimed US comic Jerry Seinfeld next month. Taking the stage on Friday June 3rd, the former star of Seinfeld is sure to entice legions of fans to the capital for the show, which is his first date in the UK in over a decade. While the comedian is doing an extensive tour of his home country, the performance at the O2 is the only available option in the UK this year. He is widely revered for the eponymous TV series Seinfeld, which he wrote alongside fellow comedy legend Larry David. The programme was a break ...

Vincent Clerc will be one of the high-profile athletes taking part in the Orangina Beach Rugby competition in Paris next month. The French international winger currently plays for Stade Toulousain, but he will be allowed to take part in this fun and exciting tournament at the Palais Omnisports Paris Bercy on Friday June 3rd. Clerc will be joined by Christophe Dominici and Serge Betsen in lining up for the event, with six teams involved in total. The organisers revealed that the Paris spectacle has been organised after successful competitions in Marseille and Toulouse ...

Most people will choose their computer screen cleaner without giving it much of a thought. They will simply pick up the one that they can grab most easily on the store shelf, or they will get something that they know from a flashy television advertisement. However, if you choose your PC display cleaner like that, the least that might happen is that your screen will not get clean at all. The most that can happen is that you can end up permanently damaging your screen altogether. To put it simply, you have to choose your computer monitor cleaner with care. Here are some ...

Taylor Morrison will be the exclusive builder in Avalon at Cinco Ranch, a gated enclave and the fourth prestigious Avalon community for Taylor Morrison in the Houston area. While Cinco Ranch has gated custom-home neighborhoods, Avalon at Cinco Ranch is the first gated neighborhood to be developed in Cinco Ranch by a volume builder offering homes priced from the $400,000s. "Avalon at Telfair opened last year, in the middle of a deep national recession, with an overwhelming response and record sales on opening weekend and home buyers waiting for new sections," ...

The Unlock Club is actively seeking resellers, who are interested in earning extra money with no upfront costs. When you become a reseller with The Unlock Club, you are working with a global network. Offering mobile cell phone unlocking service to over 220 countries, 800 mobile phone carriers, and over 8,000 mobile phones, The Unlock Club is an industry innovator and an industry leader. Making use of the Blackberry unlock server means that Blackberry phones can be freed from SIM restrictions. The value of a phone is greatly increased when it's been unlocked, and roaming ...

Sony Ericsson offers the one-of-a-kind Xperia PLAY, a PlayStation certified Android smartphone. This full-featured smartphone comes complete with bona fide game controls. You can get your game on wherever you go with the Xperia PLAY. You'll have the choice between pre-loaded games and an ever-growing list of additional amusements that you can download. The very latest Google apps are included with the Xperia Play, which means you can always find your way. Use hands-free Google Voice Search to call, text, and utilize other functions of this android mobile phone that even ...

Shutterfly, a leading Internet-based social expression and personal publishing service, today releases its new line of birthday cards and stationery. With more than 120 new birthday invitations and a new assortment of corresponding thank you cards, Shutterfly's birthday stationery collection features traditional, as well as bright and bold styles, that complement celebrations for all ages. Finding and sending the right birthday party invitation has never been easier. "Birthday invitations should reflect the style and personality of the guest of honor, so choose ...

RTOG reports on the largest trial to-date for patients with newly diagnosed glioblastoma demonstrating the importance and feasibility of prospective molecular analysis of tumor tissue although finding that patients received no additional benefit from dose-intensive temozolomide as compared to standard adjuvant temozolomide after combined temozolomide and radiotherapy. The integration of tumor analysis with the clinical trial and international collaboration, major components of this unprecedented study, will significantly impact future trial design, ultimately leading to ...

BIRMINGHAM, Ala. – In the first head-to-head comparison of the three most common drugs used at the time of a kidney transplant to prevent organ rejection, researchers found that the least expensive drug – at one-half to one-fifth the price – is as safe and effective as the other two, according to a paper published by University of Alabama at Birmingham researchers in the May 19, 2011, issue of the New England Journal of Medicine. Based at UAB, researchers in the INTAC trial spent three years following 474 patients who had undergone kidney transplants at 30 U.S. transplant ...

Alexandria, Va. – The American Society of Clinical Oncology (ASCO) today highlighted several studies in a press briefing from among more than 4,000 abstracts publicly posted online at www.asco.org in advance of ASCO's 47th Annual Meeting. An additional 17 plenary, late-breaking and other major studies will be released in on-site press conferences at the Annual Meeting. The meeting, which is expected to draw approximately 30,000 cancer specialists, will be held June 3-7, 2011, at McCormick Place in Chicago, Ill. The theme of this year's meeting is "Patients. Pathways. ...

Philadelphia, PA, May 18, 2011 – Abnormal uterine bleeding (AUB) in women of reproductive age may be due to a wide range of disorders or pathologies. Until now, there has been no universally accepted method for classifying such patients, which has impeded basic science and clinical investigation, as well as the practical, rational, and consistent application of medical and surgical therapy. As the result of a stringent 5-year review process, a multinational group of clinician–investigators with broad experience in the investigation of AUB has now agreed on a classification ...

A human genetic variant associated with an almost 30 percent reduced risk of developing severe malaria has been identified. Scientists from the Bernhard Nocht Institute for Tropical Medicine (BNITM), Hamburg, and Kumasi University, Ghana, reveal that a variant at the FAS locus can prevent an excessive and potentially hazardous immune response in infected children. The study appears in the open-access journal PLoS Genetics on May 19. Severe malaria is a major public health burden in Sub-Saharan Africa, where approximately one million individuals die each year as a result ...

A rose by any other name would smell as sweet; the saying is perhaps a testament to the acute sense of smell that is unique to mammals. Paleontologists have now discovered that an improved sense of smell jumpstarted brain evolution in the ancestral cousins of present-day mammals. The research will appear in the 20 May 2011 issue of the journal Science, which is published by AAAS, the international, nonprofit science society. The findings may help explain why mammals evolved such large and complex brains, which in some cases ballooned 10 times larger than relative body ...

Mammals first evolved their characteristic large brains to enable a stronger sense of smell, according to a new study published this week in the journal Science by paleontologists from The University of Texas at Austin, Carnegie Museum of Natural History and St. Mary's University in San Antonio. This latest study is the first to use CT technology, similar to medical scanners, to reconstruct the brains of two of the earliest known mammal species, both from the Jurassic fossil beds of China. The 3D scans revealed that even these tiny, 190-million-year-old animals had developed ...

PHILADELPHIA – Discovering the step-by-step details of the path embryonic cells take to develop into their final tissue type is the clinical goal of many stem cell biologists. To that end, Kenneth S. Zaret, PhD, professor of Cell and Developmental Biology at the Perelman School of Medicine at the University of Pennsylvania, and associate director of the Penn Institute for Regenerative Medicine, and Cheng-Ran Xu, PhD, a postdoctoral researcher in the Zaret laboratory, looked at immature cells called progenitors and found a way to potentially predict their fate. They base ...

Pittsburgh, Pennsylvania… Paleontologists have often wondered why mammals—including humans—evolved to have larger brains than other animals. A team of paleontologists now believe that large brains may have developed in mammals to facilitate an acute sense of smell, according to a new paper published today in the prestigious journal Science. The team also noticed enlargement in the areas of the brain that correspond to the ability to sense touch through fur; this sense is acutely developed in mammals. Scientists used high-resolution CT scans to study rare 190-million-year-old ...

After the death of Osama bin Laden, New York personal injury lawyer David Perecman reaffirmed his commitment to help the heroes who are still battling illnesses connected to 9/11. For many individuals, the death of bin Laden brought closure. The death also served to rekindle memories of those who volunteered to assist at the World Trade Center site after the 9/11 attacks. The lives of many Ground Zero volunteers were changed in challenging ways. Rescue and recovery workers and others are still suffering from health consequences related to the World Trade Center disaster. "People ...

SEATTLE – Researchers at Fred Hutchinson Cancer Research Center have discovered a new drug target for squamous cell carcinoma – the second most common form of skin cancer. Scientists in the laboratory of Valeri Vasioukhin, Ph.D., have found that a protein called alpha-catenin acts as a tumor suppressor and they also have unlocked the mechanism by which this protein controls cell proliferation. The findings by Vasioukhin and colleagues will be published May 24 in Science Signaling. For the study, the researchers studied mice that were bred to lack a copy of the gene that ...

Scientists at Penn State University have achieved a major milestone in the attempt to assemble, in a test tube, entire chromosomes from their component parts. The achievement reveals the process a cell uses to package the basic building blocks of an organism's entire genetic code -- its genome. The evidence provided by early research with the new procedure overturns three previous theories of the genome-packaging process and opens the door to a new era of genome-wide biochemistry research. A paper describing the team's achievement will be published in the journal Science ...

In March, four Democratic U.S. Senators, Harry Reid, D-Utah, Chuck Schumer, D-N.Y., Frank Lautenberg, D-N.J., and Tom Udall, D-N.M., drafted a letter requesting that Apple, Google and Research in Motion (or RIM) eliminate the applications (user-friendly computer programs for specific tasks) on mobile communication devices that warn drivers of the locations of drunk-driving checkpoints. The next day, RIM, the manufacturer of the BlackBerry agreed to the removal of driving-under-the-influence (DUI/DWI) checkpoint functionality on its BlackBerry devices. Google later ...

On Friday, April 1, 2011, a Southwest Airlines Boeing 737-300 experienced a rapid decompression when the metal fuselage skin tore apart, leaving a 5X1 foot hole. This kind of event is rare, but can, and has been, catastrophic when it does occur. In 1988, another Boeing 737, a 200 model, experienced a similar, but much worse, event over Hawaii. In that case, the skin on the entire front section of the aircraft cabin was denuded, leaving the passengers sitting in the first several rows completely exposed, with the aircraft being held together by two metal spars running ...

Researchers at the University of California, San Diego School of Medicine have uncovered new details of an unusual biological mechanism in the brains of diverse species that not only helps regulate how their brains develop, but also how they function later in life. The discovery could lead to new biomarkers for specific neurological diseases in humans and, possibly, the development of drugs to cure them. The research, by Miles F. Wilkinson, PhD, professor of reproductive medicine and a member of the UCSD Institute for Genomic Medicine, and colleagues, is published in ...

Thinking about, let alone preparing for, divorce before you are even married is not what most of us want to do. Whether we believe that divorce will never happen to us or whether we just choose to ignore the possibility, the fact remains that almost half of all marriages in the United States end in divorce. One way to enter into a marriage prepared for all outcomes is to create a prenuptial agreement. Creating this agreement doesn't mean that your marriage will eventually come to an end. Rather, creating a prenuptial agreement is just a way for you and your spouse to ...