ANN ARBOR, Mich.---The first national study of the prevalence of multiple partner fertility shows that 28 percent of all U.S. women with two or more children have children by more than one man. The study will be presented April 1 in Washington, D.C., at the annual meeting of the Population Association of America. "I was surprised at the prevalence," said demographer Cassandra Dorius, a postdoctoral fellow at the University of Michigan Institute for Social Research. "Multiple partner fertility is an important part of contemporary American family life, and a key component ...

ANN ARBOR, Mich.---World population will reach 7 billion this year, prompting new concerns about whether the world will soon face a major population crisis. "In spite of 50 years of the fastest population growth on record, the world did remarkably well in producing enough food and reducing poverty," said University of Michigan economist David Lam, in his presidential address at the annual meeting of the Population Association of America. Lam is a professor of economics and a research professor at the U-M Institute for Social Research. The talk is titled "How the World ...

Biological invasions get less prime-time coverage than natural disasters, but may be more economically damaging and warrant corresponding investments in preparedness and response planning, according to three biologists writing in the April issue of BioScience. Anthony Ricciardi of McGill University and his coauthors point out that species invasions are becoming more frequent worldwide, largely because of international trade. Although many alien species establish themselves in a new location without causing harm, the worst biological invasions may cause multiple extinctions ...

Ulcerative colitis (UC) is an inflammatory bowel disease thought to be related to aberrant activation of the immune system in the intestine. Recent research has also suggested that regulated cell death (apoptosis) of the intestinal epithelial cells is a contributing factor to the pathogenesis. However, the molecular mechanisms that control the cellular response to inflammation are incompletely understood. In this paper, Lin Zhang, at the University of Pittsburgh, in Pennsylvania, found that in mice, a protein called PUMA (p53 upregulated modulator of apoptosis) was responsible ...

Cells control which genes they express by multiple mechanisms, one of which is the direct modification of DNA with small molecules. Methylation of genes effectively silences them, and excess DNA methylation, particularly of genes that control the cell cycle, is known to promote cancer formation. However, it is unclear whether the enzymes that modify DNA in this way target specific genes or whether random modifications select cells for enhanced tumorigenic capactiy. In new research, Rudolf Jaenisch and colleagues, at the Whitehead Institute in Cambridge, Massachusetts, ...

EDITOR'S PICK Cat's out of the bag: PUMA contributes to ulcerative colitis Ulcerative colitis (UC) is an inflammatory bowel disease thought to be related to aberrant activation of the immune system in the intestine. Recent research has also suggested that regulated cell death (apoptosis) of the intestinal epithelial cells is a contributing factor to the pathogenesis. However, the molecular mechanisms that control the cellular response to inflammation are incompletely understood. In this paper, Lin Zhang, at the University of Pittsburgh, in Pennsylvania, found that in ...

Bombardments of 'micro-meteorites' on Earth and Mars four billion years ago may have caused the planets' climates to cool dramatically, hampering their ability to support life, according to research published today in the journal Geochimica et Cosmochimica Acta. Scientists from Imperial College London studied the effects of the Late Heavy Bombardment (LHB), a period of time in the early Solar System when meteorite showers lasting around 100 million years barraged Earth and Mars. This bombardment discharged sulphur dioxide into the upper atmospheres of both planets and ...

Leading dentists in Smyrna, Dr. James C. Pitts and Dr. Joseph M. Pitts, are pleased to introduce patients to a new avenue for communication and education through the launch of the practice's innovative website. The new informative website was created in order to enhance patient awareness of dental health care. The new website for this dentist in Smyrna offers a wide array of valuable tools and information that patients can use to better inform themselves of various dental health care topics. Patients can visit this Smyrna dentist's website via the Internet at any moment ...

Focusing on interdisciplinary research is now leading to breakthroughs in bio nanotechnology research. A new method for drug development has become a reality. Four years ago, the biologist Karen Martinez almost didn't believe in the research project herself when she started with her team working on it, but now it has been proven. Together with colleagues at the Nano-Science Center, her team has been able to combine nanoscale materials and technologies that are traditionally used for electronic devices with individual living cells. The researchers have shown that cells ...

Study shows, for the first time, the successful reprogramming of diseased human hepatocytes into induced pluripotent stem cells (iPSC).1 Results also found differentiation into mature hepatocytes was more efficient than that with fibroblast-derived iPSCs. The generation of diseased hepatocyte-derived human iPSC lines provides a good basis for the study of liver disease pathogenesis. Such technology could give a potentially unlimited reservoir of cells for the treatment of human liver diseases: generating genetically corrected liver cells via auto-transplantation of ...

Skilled West Orange dentist, Dr. Paul Feldman, allows patients to submit reviews of himself, his practice and his staff. The reviews are easily accessible via the practice's website and allow patients to view how other patients' experiences were. Patients can visit the website for this West Orange, NJ dentist to read reviews from previous patients who have received treatment from Dr. Feldman. "It is important that I know what my patients concerns are and what I am doing correctly. I value their opinion and the patient review section allows me to find out what they think, ...

This study establishes a unique system to perform in vivo RNAi screens for genetically dissecting the cellular signalling networks that regulate hepatocyte proliferation during chronic liver damage.1 Functional in vivo validation studies show that stable knockdown of the candidate gene by different shRNAs can significantly increase the repopulation efficiency of mouse hepatocytes and also increase the regenerative capacity of chronically damaged mouse livers. Such detailed understanding of the signalling pathways involved in hepatocyte proliferation control holds the ...

Berlin, Germany, 01 April 2011: Findings from two new studies presented today at the International Liver CongressTM confirm that there are options for clinicians to expand the pool of liver grafts for use in patients with liver disease. A UK retrospective study analysed liver transplant donation after cardiac death (DCD) between May 2001 and October 2010.1 186 DCD allografts were used for transplantation and included 19 paediatric recipients. Overall the study found positive outcomes of transplant, with an overall patient survival of 89.9%, 85.6% and 83.6% at one, three ...

Drs. Yung and Jelinek, experienced Warrenton dentists, are pleased to announce the addition of a smile gallery to their innovative website. Patients can now access pictures of previous patient's before and after treatment photos for a look at Drs. Yung and Jelinek's expertise and skillful cosmetic work. When accesses the online smile gallery, patients have the option to view before-and-after photos of procedures such as: anterior crowns, bleaching, crowns, crown replacement, implants and bridges, implants and crowns, orthodontics, and porcelain veneers. "We want our ...

Berlin, Germany, Friday 01 April 2011: Early data from phase I trials of an HCV vaccine presented today at the International Liver CongressTM show encouraging results, with high immunogenicity and good safety profile.1,2 In the first study1, a therapeutic T-cell vaccine, based on novel adenoviral vectors was used on a small population of treatment naive patients with chronic genotype 1 HCV infection. Intra-muscular vaccination was administered 2 or 14 weeks into a 48-week course of treatment with Peg-IFNa2a/ribavirin. 50% of vaccinated patients had CD4+ and CD8+ HCV specific ...

Berlin, Germany, Friday 1st April 2011: Highly anticipated data from a number of clinical trials presented for the first time at the International Liver CongressTM confirmed that a range of new proteases inhibitors will help treat patients who have previously failed therapy for the treatment of chronic hepatitis C.1,2,3,4,5 The treatments have been tested for efficacy and safety in combination with PegIFN-alpha and ribavirin in patients that have previously failed treatment (either non-responder or relapse). Following different treatment and dosing, all of the trials ...

A new study presented today at the International Liver CongressTM shows a novel pathway where activated natural killer (NK) cells expressing death ligands may excessively down-modulate the antiviral immune response in chronic HBV patients.1 Blocking the TNF-related apoptosis-inducing ligand (TRAIL) pathway partially reconstitutes HBV-specific T cells, suggesting that these cells are vulnerable to NK cell-mediated apoptosis through this death ligand pathway. NK cells are one of the main effectors of the innate immune response that plays a key role in containing intracellular ...

777 Dragon Casino, who assert that they are the best Asian online casino, have definitely stepped up to the plate with their latest Casino Payout Reports. With the latest payout report that has been released by the independent auditing body who regularly audits the casino, during the month of February, 2011, Poker Games have proven to be a prominent part of the casino's payouts as they paid out 100.16%! Jessica Drake, spokesperson and manager at the casino, explained, "Receiving our payout report on a monthly basis keeps us in the know about how well our players are ...

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Eating a fatty fast food meal is never good for you, but washing that meal down with a coffee is even worse, according to a new University of Guelph study. Researcher Marie-Soleil Beaudoin has discovered not only that a healthy person's blood sugar levels spike after eating a high-fat meal, but that the spike doubles after having both a fatty meal and caffeinated coffee – jumping to levels similar to those of people at risk for diabetes. "The results tell us that saturated fat interferes with the body's ability to clear sugars from the blood and, when combined with ...

Contact: Cassandra Bianco cbianco@crt-tanaka.com 646-218-6009 Federation of Quebec Maple Syrup Producers Could maple syrup from Canada be the next champion food? Maple syrup may pack similar health benefits to those found in berries, tea, red wine and flax seed New York – April 1, 2011 - There's more good news about pure maple syrup from the University of Rhode Island (URI). Researchers there have now identified 54 compounds in maple syrup from Canada, double the amount previously reported, and many with antioxidant activity and potential health benefits. In laboratory ...

The new TNM 7 lung cancer staging system seems to be a better predictor of local or regional recurrence of lung cancer following surgery, according to a study published in the April issue of the Journal of Thoracic Oncology. Being able to better define which patients might experience a cancer recurrence is important, especially given the controversies surrounding the use of adjuvant therapies, particularly postoperative radiation therapy (RT), for patients with non-small cell lung cancer (NSCLC). In 2009, the International Association for the Study of Lung Cancer (IASLC) ...

A component in soybeans increases radiation's ability to kill lung cancer cells, according to a study published in the April issue of the Journal of Thoracic Oncology, the official monthly journal of the International Association for the Study of Lung Cancer. "To improve radiotherapy for lung cancer cells, we are studying the potential of natural non-toxic components of soybeans, called soy isoflavones, to augment the effect of radiation against the tumor cells and at the same time protect normal lung against radiation injury," said Dr. Gilda Hillman, an associate professor ...