ORLANDO, FL (April 5, 2011) – Cancer risk increases with age, and scientists have long perceived a possible evolutionary tradeoff between longer lifespan and greater risk of cancer. Now, researchers at Fox Chase Cancer Center find direct evidence for that tradeoff in new data showing that expression of a key tumor suppressor protein induces premature aging in mice. Greg H. Enders, MD, PhD, associate professor in the Epigenetics and Progenitor Cell Program at Fox Chase, will present the results at the AACR 102nd Annual Meeting 2011 on Tuesday, April 5. "I didn't anticipate ...

ORLANDO, FL (April 5, 2011) – Women who have children, particularly early in life, have a lower lifetime risk of breast cancer compared with women who do not. Now, Fox Chase Cancer Center researchers have identified a gene expression pattern in breast tissue that differs between post-menopausal women who had children and post-menopausal women who did not. The results will help scientists understand why pregnancy reduces breast cancer risk and may help them develop chemopreventive strategies that can provide similar protection for women who did not have children. Pregnancy ...

BALAM Dance Theatre: From Bali to the Bronx commences BALAM Dance Theatre's (BALAM) spring 2011 season with a FREE performance on Thursday, April 28, 12:30-1:45 p.m., at Lehman College's Lovinger Theatre, 250 Bedford Park Boulevard, Bronx, New York. BALAM is a New York City-based company that offers a new vision of contemporary dance by fusing ballet, modern and diverse cultural dance styles with Balinese theatre. BALAM Dance Theatre: From Bali to the Bronx celebrates the arrival of spring and the company's recent successful tour of Bali, Indonesia by creating a new ...

ORLANDO, FL (April 5, 2011) –Tumor suppressor genes normally control the growth of cells, but cancer can spring up when these genes are silenced by certain chemical reactions that modify chromosomes. Among the most common culprits responsible for inactivating these genes are histone deacetylases, a class of enzymes that remove acetyl groups from DNA-scaffolding proteins, and DNA methyltransferases, a family of enzymes that add methyl groups to DNA. Drugs that counteract these enzymes, and thus reactivate tumor suppressor genes, are promising cancer therapies. For example, ...

OAK BROOK, Ill. – Computed tomography examinations of children in hospital emergency departments increased substantially from 1995 to 2008, according to a new study published online and in the June print edition of Radiology. Researchers said the findings underscore the need for collaboration among medical professionals to ensure that pediatric CT is appropriately ordered, performed and interpreted. "We need to think creatively about how to partner with each other, with ordering clinicians and with CT manufacturers to ensure that all children are scanned only when it ...

Your Plot Thickens http://www.yourplotthickens.com Published writer and former magazine editor, Lara Sterling, announces that Your Plot Thickens, a writing school based in the South Bay of Los Angeles, has joined forces with the Mary Pickford Institute in Los Angeles to develop the Mary Pickford Studio. The Mary Pickford Institute functions to cultivate awareness of film pioneer Mary Pickford's life while also providing outreach to at-risk youth through a Mobile Classroom, which is, in essence, a digital production and editing suite on wheels. The Mary Pickford Studio ...

VIDEO: Neuroscientist Steven Laviolette of the Schulich School of Medicine & Dentistry at the University of Western Ontario has identified the brain pathway responsible for the effects of drugs like marijuana... Click here for more information. Drugs like marijuana act on naturally occurring receptors in the brain called cannabinoid receptors. However, the mechanisms by which these drugs produce their sensory and mood altering effects within the brain are largely unknown. ...

Research shows that vibrations in the inner ear continue even after a sound has ended, perhaps serving as a kind of mechanical memory of recent sounds. In addition to contributing to the understanding of the complex process of sound perception, the results may shed light on other fascinating aspects of the auditory system, such as why some gaps between sounds are too brief to be perceived by the human ear. The study is published by Cell Press in the April 5th issue of Biophysical Journal. The inner ear contains a structure called the cochlea that serves as the organ ...

Yoga studios of every style are filling their boutiques with the latest additions to this already fun collection of yoga shaped cookie cutter kits. Expanding the collection this season, The Kitchen Yogi's (http://thekitchenyogi.com) number one sellers are "Yogi Mommy", "Warrior I", and "Crow Pose." These cookie cutter kits are bringing smiles to yogi worldwide! Who wouldn't want to eat a cookie in the shape of Warrior I? Each kit includes an asana cookie cutter, delicious cookie recipe and how-to yoga instructions. These yoga products are available for wholesale ...

Oakland, Calif., April 5, 2011 — Breast cancer survivors who experience large weight gain have an increased risk of death after diagnosis, according to research scientists at the Kaiser Permanente Division of Research in Oakland, Calif. Breast cancer survivors who experienced large weight gain (10 percent or more over their pre-diagnosis weight) were 14 percent more likely to experience a cancer recurrence compared to women whose weight remained stable (within 5 percent of pre-diagnosis weight) following diagnosis. The study results are being presented at the American ...

WINSTON-SALEM, N.C. – April 5, 2011 – Meditation produces powerful pain-relieving effects in the brain, according to new research published in the April 6 edition of the Journal of Neuroscience. "This is the first study to show that only a little over an hour of meditation training can dramatically reduce both the experience of pain and pain-related brain activation," said Fadel Zeidan, Ph.D., lead author of the study and post-doctoral research fellow at Wake Forest Baptist Medical Center. "We found a big effect – about a 40 percent reduction in pain intensity and ...

Second World Sessions heats up on Thursday April 14th 2011, from 10pm until 4am at Sutra Lounge, 16 1st Avenue, New York City! the VIBE: Tribal. Global. Deep. Soulful. Sexy. Decadent. the WORLD: A deep warm place where lotus lamps mingle with candle lit spiritual eroticism. the MUSIC: Selectress Iriela (Second World) Bradford James (Seed Recordings) + Special Guest Faze Dynamik (Paris) For anyone familiar with Second World events which combine elements like ethical fashion with tribal body paint to a booming global soundtrack - they know that they are in ...

CHAMPAIGN, Ill. — A new study louses up a popular theory of animal evolution and opens up the possibility that dinosaurs were early – perhaps even the first – animal hosts of lice. The study, in Biology Letters, uses fossils and molecular data to track the evolution of lice and their hosts. It offers strong evidence, the researchers said, that the ancestors of lice that today feed on birds and mammals began to diversify before a mass extinction event killed off the dinosaurs about 65 million years ago. "This study lends support to the idea that major groups of birds ...

In today's business world the question is no longer why do Small and Medium business have so many problems with information security but more, is there a better way of understanding my business requirements and protecting my information. The complexity, compliance and requirements in business today make protecting that information not only difficult but expensive. Most have minimal knowledge and restricted capital to initiate protection for the very information that is critical to their business. This book targets small and medium business and not for profit organisations ...

Among postmenopausal women with prior hysterectomy who had used estrogen therapy for about 6 years and then stopped, longer-term follow-up indicates that the increased risk of stroke seen during the intervention period had dissipated, the decreased risk of hip fracture was not maintained, while the decreased risk of breast cancer persisted, according to a study in the April 6 issue of JAMA. "The Women's Health Initiative (WHI) Estrogen-Alone Trial was a double-blind, placebo-controlled, randomized clinical trial evaluating the effects of conjugated equine estrogens (CEE) ...

The big day is rapidly approaching, and you're more than a little stressed about how you're going to look in that spectacular in that costly wedding dress. According top fitness trainer and OC Boot Camp Founder Rod Edmondson, there are 10 mistakes that women routinely make to unintentionally sabotage their fitness goals. 1. Start by starving yourself! Drastically reducing your caloric intake is tempting, but don't do it! It not only depletes essential vitamins and minerals from your body, but also slows your metabolism and prompts your body to cannibalize lean muscle ...

Higher levels in blood of the protein clusterin, also known as apolipoprotein J, are significantly associated with the prevalence and severity of Alzheimer's disease, but not with the risk of onset of new disease, according to a study in the April 6 issue of JAMA. Clusterin levels have been found to be increased in brain and cerebrospinal fluid of patients with Alzheimer disease (AD), and have been suggested to be involved in the pathogenesis of AD. "Plasma clusterin was reported to be associated with brain atrophy, baseline disease severity, and rapid clinical progression ...

In an analysis of opioid prescription patterns and deaths, receiving higher prescribed doses is associated with an increased risk of opioid overdose death, but receiving both as-needed and regularly scheduled doses is not associated with overdose risk, according to a study in the April 6 issue of JAMA. The rate of overdose death has increased sharply in the United States in the past decade and overdose death is a pressing public health problem, according to background information in the article. "Between 1999 and 2007, the rate of unintentional overdose death in the United ...

Six expert business coaches and consultants are launching a "virtual summit" designed to fit the busy schedules of women business owners. The Make it Happen! Virtual Summit kicks off April 19 and focuses on presenting information that can be implemented quickly into action steps leading to high-impact results. The Make it Happen Virtual Summit is geared to women who are ready to strategically prioritize their business and life goals to enhance professional success and personal fulfillment with less stress. Topics include developing a powerful profit-boosting marketing ...

An analysis of data from 10 studies indicates that the presence of low frequency (also called "minority") human immunodeficiency virus type 1 (HIV-1) drug resistance mutations, particularly those involving nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance, are significantly associated with an increased risk of first-line antiretroviral treatment failure, according to an article in the April 6 issue of JAMA. Using traditional tests, the prevalence of transmitted drug resistance mutations is estimated to be between 8 percent and 16 percent among HIV-1 infected ...

Death rates after hospitalization for heart failure have dropped for veterans age 80 and older, but rehospitalizations remain frequent, according to a study in the American Heart Association journal Circulation: Heart Failure. Results of the study highlight a need to better identify which patients among the oldest are more likely to be rehospitalized not just for heart failure, but for any reason, said Rashmee Shah, M.D., lead author of the study and postdoctoral fellow in the Department of Health Research and Policy at Stanford University School of Medicine in Palo Alto, ...

Advanced International Translations (AIT), a leading supplier of translation management software for agencies and freelancers, became the first member-provider software company in the American Translators Association (ATA). ATA's Member-Provider Program was established to provide support to members in their practice of translation and interpreting. Vendors in the program are selected after careful review of the company's products, services, reliability, and value. The selection process includes feedback and recommendations from ATA members about the vendor and its products. Participation ...

Despite Federal Drug Administration regulation of the approval and use of pharmaceutical products, "off-label" marketing of drugs (for purposes other than those for which the drug was approved) has occurred in all aspects of the US health care system. In a study published in this week's PLoS Medicine, Aaron S. Kesselheim from Brigham and Women's Hospital, Boston, USA and colleagues report that the most common alleged off-label marketing practices also appear to be the most difficult to control through external regulatory approaches. They identified three main goals of alleged ...

A multifaceted approach that addressed deficiencies in clinical knowledge, skills, motivation, resources, and the organization of care was associated with improvements in practice for high mortality conditions in young children in rural Kenya compared with less comprehensive approaches. This finding from a novel study by Philip Ayieko from the KEMRI-Wellcome Trust Research Programme, Nairobi, Kenya, and colleagues, published in this week's PLoS Medicine, is important as it suggests that specific efforts are needed to improve pediatric care in rural areas of poor countries ...

Using a cross-sectional study, Stefan Flasche and colleagues investigated the effects of the UK pneumococcal vaccination program on serotype-specific carriage and invasive pneumococcal disease. There are more than 90 Streptococcus pneumoniae serotypes that can cause invasive pneumococcal disease (IPD). The pneumococcal conjugate vaccine PCV7 contains antigens from seven serotypes responsible for IPD. Immunization with PCV7 prevents both IPD disease and carriage of these seven serotypes, but after vaccination non-vaccine serotypes could colonize the nasopharynx. There ...