San Antonio, Texas (June 6, 2011)—A study presented at SNM's 58th Annual Meeting focuses on the effect that breathing irregularities have on the accuracy of 4D positron emission tomography (PET) scans and outlines a PET imaging method that reduces "motion artifacts" or image blurring arising from respiratory motion. Non-gated PET imaging with 4D computed tomography may be useful for imaging patients who do not benefit from the use of respiratory gating, most notably patients with erratic breathing. "Breathing irregularities can lead to significantly underestimated lesion ...

San Antonio, Texas (June 6, 2011)—Scientists presented new research at SNM's 58th Annual Meeting that has the potential to help physicians detect breast cancer by imaging the proliferation of blood vessels carrying oxygen and nutrients to breast tumors. Their study is evaluating a new imaging agent that is naturally drawn to angiogenesis—the development of new blood vessels in tissues both normal and cancerous. This process turns malignant during the growth stage of many cancerous tumors including those in breast tissue. "The positive outcomes of this study are encouraging ...

San Antonio, Texas (June 6, 2011)—A study introduced at SNM's 58th Annual Meeting may lead to the next wave of cancer imaging by helping to develop a molecular imaging agent that detects many malignant cancers' incessant development of blood vessels—a process called angiogenesis. A protein biomarker known as CD105 has been shown to indicate tumor angiogenesis in cancer patients. "Non-invasive molecular imaging is a critical component of 21st century personalized medicine, and one of the hallmarks of cancer is angiogenesis," says Weibo Cai, PhD, assistant professor of ...

San Antonio, Texas (June 6, 2011)—Definitive proof of an adverse effect of chronic marijuana use revealed at SNM's 58th Annual Meeting could lead to potential drug treatments and aid other research involved in cannabinoid receptors, a neurotransmission system receiving a lot of attention. Scientists used molecular imaging to visualize changes in the brains of heavy marijuana smokers versus non-smokers and found that abuse of the drug led to a decreased number of cannabinoid CB1 receptors, which are involved in not just pleasure, appetite and pain tolerance but a host of ...

San Antonio, Texas (June 6, 2011)—Researchers the world over are advancing positron emission tomography (PET) as an effective method of early detection for Alzheimer's disease, a currently incurable and deadly neurological disorder. Three studies presented at SNM's 58th Annual Meeting are providing new insights into the development of Alzheimer's disease while opening the door to future clinical screening and treatments. According to the World Health Organization, an estimated 18 million people worldwide are currently living with Alzheimer's disease—a number projected ...

San Antonio, Texas (June 6, 2011)—A new study presented at SNM's 58th Annual Meeting could throw open the door to a recently established area of obesity research. Investigators have developed a novel molecular imaging agent that targets estrogenic mechanisms in the brain to find out what effect an enzyme called aromatase has on body mass index (BMI), a measurement of body fat based on height and weight. Aromatase is crucial for the production of estrogen in tissues throughout the body, including the brain. According to the World Health Organization, worldwide obesity ...

San Antonio, Texas (June 6, 2011)—Researchers are halting kidney cancer with a novel form of radioimmunotherapy that zeroes in on antigens associated with renal cell carcinoma. Patients with progressive kidney cancer receiving up to three doses of the therapy show dramatic slowing of cancer growth and stabilization of their disease. "This study is another step forward in developing a cancer therapy that has the potential to provide additional treatment options for patients with renal cell carcinoma," says Wim Oyen, MD, professor and chairman of the department of nuclear ...

San Antonio, Texas (June 6, 2011)—Research introduced at SNM's 58th Annual Meeting could be a sign of hope for patients with neuroendocrine cancer not responding well to standard therapies. Most radiotherapies use medical isotopes that emit beta radiation. The therapy in this study employs alpha particles, which have potential for higher potency. In fact, one single atom could be enough to kill an entire cancer cell. "Until now, the usage of alpha radionuclides was limited to direct injection into the tumor or the use of only very small doses," says Clemens Kratochwil, ...

San Antonio, Texas (June 6, 2011)—Investigators at SNM's 58th Annual Meeting are presenting results from a phase 1 clinical trial for a cancer therapy that has the potential to kill colorectal tumors with less destruction of healthy tissue. Further research could lead to the use of this radioimmunotherapy to eliminate residual cancer after surgery or as a standard treatment to keep tumors from returning or spreading to other organs. "Compared to the conventional way of guiding radiation to tumors with radiolabeled antibody, pretargeted radioimmunotherapy offers an attractive ...

San Antonio, Texas (June 6, 2011)—Research presented at SNM's 58th Annual Meeting is taking targeted molecular imaging to a new level by combining two commonly used imaging agents into one molecular imaging procedure. The combination of these agents creates a comprehensive examination of the extent of cancer spread within a variety of organ systems in the body. "During a time when health care costs are under intense scrutiny, consolidated procedures such as this one that provide comprehensive imaging data are a benefit to everyone—to clinicians, healthcare administrators ...

Spinal muscular atrophy (SMA) is the leading genetic cause of death in children under 2, with no treatment other than supportive care. In the Proceedings of the National Academy of Sciences (Early Edition, week of June 6), researchers at Children's Hospital Boston show how loss or mutation of the SMA gene causes progressive muscle degeneration and weakness, and suggest a promising approach to treating the condition, sometimes referred to as a "Lou Gehrig's disease of babies." Spinal muscular atrophy, or SMA, affects one in every 1 in 6,000-10,000 infants, but an estimated ...

San Antonio, Texas (June 6, 2011)—A study presented at SNM's 58th Annual Meeting may provide a new tool for detection of malignant-stage ovarian cancer. Researchers found that positron emission tomography and computed tomography (PET/CT), which images both functional and anatomical changes in the body, was useful for preoperative cancer imaging of ovarian masses when used with a radiotracer that is actively metabolized by cells as fuel. Physicians imaging patients suspected of having malignant tumors can see where cancerous cells are hyper-metabolizing the tracer and accurately ...

San Antonio, Texas (June 6, 2011)—A study revealed at SNM's 58th Annual Meeting is comparing the breast-tumor detection capabilities of two very different imaging technologies—breast-specific gamma imaging (BSGI), which provides functional images of breast physiology, and ultrasound—for women with complex breast imaging cases that require further evaluation. Many women who have dense breast tissue (radiodense breasts) are difficult to image using mammography, currently the gold standard of breast imaging. For women whose mammograms are not clear enough to determine whether ...

San Antonio, Texas (June 6, 2011)—Patients undergoing molecular imaging to evaluate their stomach's ability to clear food are going to have an altogether new kind of breakfast. A study presented at SNM's 58th Annual Meeting has confirmed that nuclear medicine technologists can effectively use oatmeal products radiolabeled with a medical isotope to target and image the emptying of the stomach. "The current standard for molecular imaging of gastric emptying is radiolabeling egg meal, but there are patients who, either due to lifestyle choices or allergies, cannot eat eggs," ...

(Boston) - Boston University School of Medicine (BUSM) researchers found that girls who followed the Dietary Approach to Stop Hypertension (DASH) diet pattern had a lower incidence of excess weight gain as measured by body mass index (BMI) over the 10-year period of their adolescence. These findings are reported in the Archives of Pediatrics & Adolescent Medicine. Obesity is a major public health problem, with 17 percent of American children overweight and 67 percent of adults either overweight or obese. Excess weight during childhood leads to numerous health problems ...

The implementation of virtual water into trading deals has been suggested as a realistic solution to solving the global inequality of renewable freshwater, but new research suggests that it may not be as revolutionary as first thought. In a study published today, Tuesday 7 June, in IOP Publishing's journal Environmental Research Letters, researchers have claimed that virtual water is unlikely to increase water use equality, primarily because the existing amount of virtual water is not large enough to overcome the inequalities that exist. Lead author David Seekell, ...

Boston, Mass (June 6, 2011)—A new study finds that the cancer care provided by the Veterans Health Administration (VHA) for men 65 years and older is at least as good as, and by some measures better than, Medicare-funded fee-for-service care obtained through the private sector. The study, reported in the June 7 issue of Annals of Internal Medicine, was led by Nancy Keating, an associate professor of health care policy at Harvard Medical School. Several factors could account for the high quality of VHA care. "Care in the VHA is much better coordinated than most other settings," ...

The 2011 Formula 1 Grand Prix of Europe will take place on the Valencia Street Circuit on 24, 25 and 26 June this year. Formula 1 enjoys a fan base in the millions throughout the world and also attracts spectators in their tens of thousands wherever each race is held. This summer sees the prestigious Grand Prix of Europe take place in Spain's Valencia, a city which typically enjoys massive tourist numbers each summer regardless. Valencia hotels in the port area of the city can expect a bumper week, as the city's street circuit is located in that part of town. The ...

Men who report having bullied peers in childhood appear to have an increased risk of perpetrating violence against an intimate partner in adulthood, according to a report posted online today by the Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals. The authors point out, as background information, that roughly one-quarter of women will experience violence from intimate partners, and that prior research suggests up to 40 percent of men have been perpetrators of such violence. The authors sought to determine whether a history of school bullying ...

Adolescent girls whose diet resembles one recommended for adults with hypertension appear to have smaller gains in overall body mass index (BMI) over 10 years, according to a report in the June issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals. "Excess weight during childhood leads to numerous health problems and is even associated with premature death as an adult," the authors write as background information in the article. However, the authors note that examinations of food-based dietary patterns acknowledge that consuming various ...

A brain imaging study suggests that men with a history of violent behavior may have greater gray matter volume in certain brain areas, whereas men with a history of substance use disorders may have reduced gray matter volume in other brain areas, according to a report published online today by the Archives of General Psychiatry, one of the JAMA/Archives journals. According to background information in the article, research suggests that violent behavior may stem from a complicated mix of biological, psychological, and social factors. Studies of the brains of violent individuals ...

The Kuningan day holiday is celebrated at the end of the Galungan festival, one of the most significant Hindu celebrations which marks the occasion of one's ancestors entering into heaven. Seminyak Beach is a popular place for Indonesian Hindus to spend the holiday since its pretty streets and coastal roads make ideal backdrops for Kuningan's processions and parades. Foreign tourists are also welcome to join in the celebrations and with Seminyak Beach being a popular travel destination in its own right, the town can expect to be thriving around July 16th when Kuningan ...

Difficulty remembering important dates and medications, and gathering paperwork, is more common in older individuals with mild cognitive impairment than in those with no cognition problems, according to a report in the June issue of Archives of General Psychiatry, one of the JAMA/Archives journals. According to background information in the article, mild cognitive impairment is a condition that includes some difficulty with cognition and, in the amnestic subtype (aMCI), difficulty with memory, but does not include considerable problems with daily tasks, work, or social ...

LOUISVILLE, Ky. – Research from the University of Louisville published today (June 6) in the Proceedings of the National Academy of Sciences indicates the removal of a tiny RNA molecule in mice suppresses carcinogenic tumor formation. The study appears in the journal's Early Edition online at www.pnas.org. Yong Li, Ph.D., associate professor of biochemistry and molecular biology, and his research team led by postdoctoral fellows Xiaodong Ma and Munish Kumar found that the removal of a non-coding RNA molecule known as MicroRNA 21 suppressed the formation of skin tumors ...

Patients in residential treatment programs for drug and alcohol abuse may benefit from cognitive behavioral therapy for depressive symptoms, according to a report in the June issue of Archives of General Psychiatry, one of the JAMA/Archives journals. The article notes, as background information, that depression and substance abuse often co-occur, but that individuals with both disorders are not always treated for both. "The consequences of this unmet need are great," report the authors. "The interactive nature of the two disorders leads to poorer depression and substance ...