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Cancer-seeking 'smart bombs' target kidney cancer cells

2011-06-07
San Antonio, Texas (June 6, 2011)—Researchers are halting kidney cancer with a novel form of radioimmunotherapy that zeroes in on antigens associated with renal cell carcinoma. Patients with progressive kidney cancer receiving up to three doses of the therapy show dramatic slowing of cancer growth and stabilization of their disease. "This study is another step forward in developing a cancer therapy that has the potential to provide additional treatment options for patients with renal cell carcinoma," says Wim Oyen, MD, professor and chairman of the department of nuclear ...

High-impact radiopeptide therapy halts neuroendocrine cancer

2011-06-07
San Antonio, Texas (June 6, 2011)—Research introduced at SNM's 58th Annual Meeting could be a sign of hope for patients with neuroendocrine cancer not responding well to standard therapies. Most radiotherapies use medical isotopes that emit beta radiation. The therapy in this study employs alpha particles, which have potential for higher potency. In fact, one single atom could be enough to kill an entire cancer cell. "Until now, the usage of alpha radionuclides was limited to direct injection into the tumor or the use of only very small doses," says Clemens Kratochwil, ...

New pretargeted radioimmunotherapy for colorectal cancer

2011-06-07
San Antonio, Texas (June 6, 2011)—Investigators at SNM's 58th Annual Meeting are presenting results from a phase 1 clinical trial for a cancer therapy that has the potential to kill colorectal tumors with less destruction of healthy tissue. Further research could lead to the use of this radioimmunotherapy to eliminate residual cancer after surgery or as a standard treatment to keep tumors from returning or spreading to other organs. "Compared to the conventional way of guiding radiation to tumors with radiolabeled antibody, pretargeted radioimmunotherapy offers an attractive ...

Combined imaging agents advance PET imaging of cancer

2011-06-07
San Antonio, Texas (June 6, 2011)—Research presented at SNM's 58th Annual Meeting is taking targeted molecular imaging to a new level by combining two commonly used imaging agents into one molecular imaging procedure. The combination of these agents creates a comprehensive examination of the extent of cancer spread within a variety of organ systems in the body. "During a time when health care costs are under intense scrutiny, consolidated procedures such as this one that provide comprehensive imaging data are a benefit to everyone—to clinicians, healthcare administrators ...

New approaches open up in spinal muscular atrophy

2011-06-07
Spinal muscular atrophy (SMA) is the leading genetic cause of death in children under 2, with no treatment other than supportive care. In the Proceedings of the National Academy of Sciences (Early Edition, week of June 6), researchers at Children's Hospital Boston show how loss or mutation of the SMA gene causes progressive muscle degeneration and weakness, and suggest a promising approach to treating the condition, sometimes referred to as a "Lou Gehrig's disease of babies." Spinal muscular atrophy, or SMA, affects one in every 1 in 6,000-10,000 infants, but an estimated ...

PET imaging determines malignancy in potential ovarian cancer cases

2011-06-07
San Antonio, Texas (June 6, 2011)—A study presented at SNM's 58th Annual Meeting may provide a new tool for detection of malignant-stage ovarian cancer. Researchers found that positron emission tomography and computed tomography (PET/CT), which images both functional and anatomical changes in the body, was useful for preoperative cancer imaging of ovarian masses when used with a radiotracer that is actively metabolized by cells as fuel. Physicians imaging patients suspected of having malignant tumors can see where cancerous cells are hyper-metabolizing the tracer and accurately ...

Gamma imaging provides superior tumor detection for dense breasts

2011-06-07
San Antonio, Texas (June 6, 2011)—A study revealed at SNM's 58th Annual Meeting is comparing the breast-tumor detection capabilities of two very different imaging technologies—breast-specific gamma imaging (BSGI), which provides functional images of breast physiology, and ultrasound—for women with complex breast imaging cases that require further evaluation. Many women who have dense breast tissue (radiodense breasts) are difficult to image using mammography, currently the gold standard of breast imaging. For women whose mammograms are not clear enough to determine whether ...

Oatmeal-labeling ideal for molecular imaging of stomach emptying

2011-06-07
San Antonio, Texas (June 6, 2011)—Patients undergoing molecular imaging to evaluate their stomach's ability to clear food are going to have an altogether new kind of breakfast. A study presented at SNM's 58th Annual Meeting has confirmed that nuclear medicine technologists can effectively use oatmeal products radiolabeled with a medical isotope to target and image the emptying of the stomach. "The current standard for molecular imaging of gastric emptying is radiolabeling egg meal, but there are patients who, either due to lifestyle choices or allergies, cannot eat eggs," ...

BUSM study finds higher adherence to dash-style diet reduces excess weight gain in adolescent girls

2011-06-07
(Boston) - Boston University School of Medicine (BUSM) researchers found that girls who followed the Dietary Approach to Stop Hypertension (DASH) diet pattern had a lower incidence of excess weight gain as measured by body mass index (BMI) over the 10-year period of their adolescence. These findings are reported in the Archives of Pediatrics & Adolescent Medicine. Obesity is a major public health problem, with 17 percent of American children overweight and 67 percent of adults either overweight or obese. Excess weight during childhood leads to numerous health problems ...

Virtual water cannot remedy freshwater shortage

2011-06-07
The implementation of virtual water into trading deals has been suggested as a realistic solution to solving the global inequality of renewable freshwater, but new research suggests that it may not be as revolutionary as first thought. In a study published today, Tuesday 7 June, in IOP Publishing's journal Environmental Research Letters, researchers have claimed that virtual water is unlikely to increase water use equality, primarily because the existing amount of virtual water is not large enough to overcome the inequalities that exist. Lead author David Seekell, ...

Veterans Health Administration similar or better than private sector for cancer patients ages 65+

2011-06-07
Boston, Mass (June 6, 2011)—A new study finds that the cancer care provided by the Veterans Health Administration (VHA) for men 65 years and older is at least as good as, and by some measures better than, Medicare-funded fee-for-service care obtained through the private sector. The study, reported in the June 7 issue of Annals of Internal Medicine, was led by Nancy Keating, an associate professor of health care policy at Harvard Medical School. Several factors could account for the high quality of VHA care. "Care in the VHA is much better coordinated than most other settings," ...

DirectRooms.com - Valencia Welcomes Formula 1 Fans from All Over World During 24 to 26 June 2011

2011-06-07
The 2011 Formula 1 Grand Prix of Europe will take place on the Valencia Street Circuit on 24, 25 and 26 June this year. Formula 1 enjoys a fan base in the millions throughout the world and also attracts spectators in their tens of thousands wherever each race is held. This summer sees the prestigious Grand Prix of Europe take place in Spain's Valencia, a city which typically enjoys massive tourist numbers each summer regardless. Valencia hotels in the port area of the city can expect a bumper week, as the city's street circuit is located in that part of town. The ...

Study suggests link between childhood bullying and adult intimate partner violence perpetration

2011-06-07
Men who report having bullied peers in childhood appear to have an increased risk of perpetrating violence against an intimate partner in adulthood, according to a report posted online today by the Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals. The authors point out, as background information, that roughly one-quarter of women will experience violence from intimate partners, and that prior research suggests up to 40 percent of men have been perpetrators of such violence. The authors sought to determine whether a history of school bullying ...

Adherence to certain dietary pattern associated with lower BMI in adolescent girls

2011-06-07
Adolescent girls whose diet resembles one recommended for adults with hypertension appear to have smaller gains in overall body mass index (BMI) over 10 years, according to a report in the June issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals. "Excess weight during childhood leads to numerous health problems and is even associated with premature death as an adult," the authors write as background information in the article. However, the authors note that examinations of food-based dietary patterns acknowledge that consuming various ...

Brain scans appear to show changes associated with violent behavior

2011-06-07
A brain imaging study suggests that men with a history of violent behavior may have greater gray matter volume in certain brain areas, whereas men with a history of substance use disorders may have reduced gray matter volume in other brain areas, according to a report published online today by the Archives of General Psychiatry, one of the JAMA/Archives journals. According to background information in the article, research suggests that violent behavior may stem from a complicated mix of biological, psychological, and social factors. Studies of the brains of violent individuals ...

DirectRooms.com - Hindu Holiday Draws Big Numbers to Indonesia's Seminyak Beach in Summer

2011-06-07
The Kuningan day holiday is celebrated at the end of the Galungan festival, one of the most significant Hindu celebrations which marks the occasion of one's ancestors entering into heaven. Seminyak Beach is a popular place for Indonesian Hindus to spend the holiday since its pretty streets and coastal roads make ideal backdrops for Kuningan's processions and parades. Foreign tourists are also welcome to join in the celebrations and with Seminyak Beach being a popular travel destination in its own right, the town can expect to be thriving around July 16th when Kuningan ...

Study finds older adults with mild cognitive impairment may also have some functional impairment

2011-06-07
Difficulty remembering important dates and medications, and gathering paperwork, is more common in older individuals with mild cognitive impairment than in those with no cognition problems, according to a report in the June issue of Archives of General Psychiatry, one of the JAMA/Archives journals. According to background information in the article, mild cognitive impairment is a condition that includes some difficulty with cognition and, in the amnestic subtype (aMCI), difficulty with memory, but does not include considerable problems with daily tasks, work, or social ...

UofL research shows removal of a tiny RNA molecule can inhibit cancer growth

2011-06-07
LOUISVILLE, Ky. – Research from the University of Louisville published today (June 6) in the Proceedings of the National Academy of Sciences indicates the removal of a tiny RNA molecule in mice suppresses carcinogenic tumor formation. The study appears in the journal's Early Edition online at www.pnas.org. Yong Li, Ph.D., associate professor of biochemistry and molecular biology, and his research team led by postdoctoral fellows Xiaodong Ma and Munish Kumar found that the removal of a non-coding RNA molecule known as MicroRNA 21 suppressed the formation of skin tumors ...

Cognitive behavioral therapy may benefit patients in residential substance abuse treatment programs

2011-06-07
Patients in residential treatment programs for drug and alcohol abuse may benefit from cognitive behavioral therapy for depressive symptoms, according to a report in the June issue of Archives of General Psychiatry, one of the JAMA/Archives journals. The article notes, as background information, that depression and substance abuse often co-occur, but that individuals with both disorders are not always treated for both. "The consequences of this unmet need are great," report the authors. "The interactive nature of the two disorders leads to poorer depression and substance ...

DirectRooms.com - Diving Training Course Heads for Filipino Resort of Puerto Galera from 1 to 7 July 2011

2011-06-07
Puerto Galera makes for a stunning backdrop to a training course like the PADI workshop, but also ensures that there is high demand for places on the course. The location also means that there will be higher than average demand for a Puerto Galera hotel, leading Internet-based hotel room comparison website DirectRooms.com to advise early, online booking. PADI qualification is the scuba diving industry's most popular qualification, allowing successful divers the status of being able to go diving in any location around the world. The July training course will be held in ...

Expertise provides buffer against bias in making judgments

Expertise provides buffer against bias in making judgments
2011-06-07
Roanoke, Va. -- Gratuities, gifts, sponsorship, product price, free samples, favors all can influence judgment and decision-making. If a person is influenced in their choice of cereal, the result is a bit of income for a manufacturer. But a lot of people can be impacted if a politician is influenced by support from a special interest; or the health of a handful of patients can be affected if a physician is influenced by gifts from drug reps. Scientists with the Virginia Tech Carilion Research Institute have demonstrated through behavioral research and brain scans using ...

Scotland's Lesley Paterson Wins New Hampshire Mooseman Ironman 70.3

2011-06-07
Scotland's Lesley Paterson, who won the inaugural Xterra off-road triathlon Pacific Championships in Santa Cruz in Northern California just two weeks ago, followed that up with her first ever Ironman victory at the 2011 Mooseman Ironman 70.3 in New Hampshire. Paterson finished in the time of 4 hours 30 minutes 58 seconds, 48 seconds in front of the second place Caitlin Snow. Having been injured and ill with a stomach parasite off and on for most of the past year, an injury free Paterson was finally able to put it all together for the victory, posting an even 27 minute ...

Supplement found to improve quality of life for female cancer survivors

2011-06-07
WINSTON-SALEM, N.C. – June 6, 2011 – A natural nutritional supplement, marketed for the last decade as a sexual aid, has been shown to significantly improve overall quality of life for female cancer survivors, according to researchers at Wake Forest Baptist Medical Center. The findings will be presented today at the 2011 American Society of Clinical Oncology (ASCO) annual meeting in Chicago. Interested in quality of life issues for female cancer survivors, Kathryn M. Greven, M.D., a radiation oncologist at Wake Forest Baptist, first learned of the supplement, called ...

Hawaii's "Don't Drink Yourself Fat" Campaign

Hawaiis "Dont Drink Yourself Fat" Campaign
2011-06-07
It may have started this way: one passerine flying high above a plant-free, uninhabited and unnamed island - in the Pacific, north of the equator - unknowingly drops one seed from a mud-encrusted thigh. That seed and many others brought to the islands by other birds, animals, people and the wind now feeds the island's residents and visitors. That island is presently called Hawaii. Ancient Hawaiians were innovative farmers and skilled fisherman whose customs of sharing food amongst their communities lives on today as residents of present-day Hawaii struggle to return ...

Study finds high levels of vitamin D needed for bone density drugs to work

2011-06-07
To fully optimize a drug therapy for osteoporosis and low bone mineral density (BMD), patients should maintain vitamin D levels above the limits recently recommended by the Institute of Medicine (IOM), according to a new study by researchers from Hospital for Special Surgery in New York. The study will be presented at the Endocrine Society's Annual Meeting in Boston, June 4-7. The study demonstrated that maintaining a circulating vitamin D level above 33 ng/ml is associated with a seven-fold greater likelihood of having a more favorable outcome with bisphosphonate therapy. ...
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