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GOLFIG increased progression-free survival in colorectal cancer patients

2011-04-07
ORLANDO, Fla. — Oncologists can use colorectal cancer patients' own immune system to boost the effects of chemotherapy and increase progression-free survival, according to Phase III study results presented at the AACR 102nd Annual Meeting 2011, held here April 2-6. Patients with advanced colorectal cancer are typically treated with combination chemotherapy with fluorouracil or the derivative product, capecitabine with or without levofolinic acid with irinotecan (FOLFIRI) or oxaliplatin (FOLFOX) given alone, or with the monoclonal antibodies bevacizumab, cetuximab or ...

Physical health scores predict breast cancer outcomes

2011-04-07
ORLANDO, Fla. — Breast cancer survivors with poor physical health scores had an elevated risk of poorer cancer outcomes, including recurrence and death, according to the results of an observational study presented at the AACR 102nd Annual Meeting 2011, held April 2-6. Survivors of breast cancer who had poor health scores were 27 percent more likely to experience either a recurrence of their cancer or a new breast cancer. Physical health also impacted survival quite strongly; risk of death from any cause was 65 percent greater among those with poorer health scores. Researchers ...

Strawberries may slow precancerous growth in esophagus

2011-04-07
ORLANDO, Fla. — Freeze-dried strawberries may be an alternative to drugs for the prevention of esophageal cancer, according to research presented at the AACR 102nd Annual Meeting 2011, held here April 2-6. "We concluded from this study that six months of eating strawberries is safe and easy to consume. In addition, our preliminary data suggests that strawberries can decrease histological grade of precancerous lesions and reduce cancer-related molecular events," said lead researcher Tong Chen, M.D., Ph.D., assistant professor, division of medical oncology, department ...

Fox Chase researchers find that fish oil boosts responses to breast cancer drug tamoxifen

2011-04-07
ORLANDO, FL (April 6, 2011) – Breast cancer is the second most common cancer among women, with more than 200,000 women diagnosed each year. Being exposed to estrogen over a long period of time is one factor that can increase a woman's risk of developing the disease. One way a woman can combat this risk factor is by taking the breast cancer drug tamoxifen, which interferes with the activity of estrogen. Now, researchers at Fox Chase Cancer Center have found that omega-3 fatty acids—abundant in fish—could be a safe and beneficial booster for tamoxifen therapy. Jose Russo, ...

Fox Chase researchers report that naproxen reduces tumors in a mouse model of colon cancer

2011-04-07
ORLANDO, FL (April 6, 2011) – Numerous studies show that non-steroidal anti-inflammatory drugs (NSAIDs) reduce the risk of colon cancer. However, animal studies testing the NSAID naproxen or its derivative, NO-naproxen, have focused primarily on chemically-induced tumor formation. Now, researchers at Fox Chase Cancer Center find that naproxen and NO-naproxen reduce tumor formation in a strain of mutant mice that spontaneously develop colon tumors. The data also suggest that naproxen blocks a gatekeeper step that initiates tumor formation. Margie Clapper, PhD, Co-Leader ...

Healthy welders may be at increased risk for early brain damage

2011-04-07
New research suggests that workers exposed to welding fumes may be at risk for developing brain damage in an area of the brain also affected in Parkinson's disease. The study is published in the April 6, 2011, online issue of Neurology®, the medical journal of the American Academy of Neurology. Fumes produced by welding contain manganese. Manganese is a chemical element that, even at low levels, has been linked to neurologic problems, including Parkinson's disease-like symptoms. "There are over one million workers who perform welding as part of their job functions ...

Genetic variants associated with caffeine intake identified

2011-04-07
Two genes in which variation affects intake of caffeine, the most widely consumed stimulant in the world, have been discovered. A team of investigators from the National Cancer Institute, Harvard School of Public Health, Brigham and Women's Hospital, and the University of North Carolina at Chapel Hill examined genetic variation across the entire genome of more than 47,000 individuals from the U.S., as described in the open-access journal PLoS Genetics. The genes identified were CYP1A2, which has previously been implicated in the metabolism of caffeine, and AHR, involved ...

An international study in China finds strawberries may slow precancerous growth in the esophagus

2011-04-07
COLUMBUS, Ohio – Eating strawberries may be a way to help people at risk of esophageal cancer protect themselves from the disease, according to a new study by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) and researchers in China. Dr. Tong Chen will present the findings during a press briefing at 8 a.m. April 6 at the American Association for Cancer Research (AACR) 102nd meeting 2011 in Orlando, Fla. The study is the first-ever collaborative Ohio State cancer ...

Placing value, price on new drugs: The challenge facing new UK policy, say Hopkins bioethicists

2011-04-07
The United States should pay close attention to how the United Kingdom carries out plans to assess a new drug's worth using factors that go beyond clinical and cost effectiveness, according to researchers at the Johns Hopkins Berman Institute of Bioethics. In a commentary to appear in the April 7 issue of the New England Journal of Medicine, the bioethicists detail and discuss a new, "value-based pricing" policy proposed by the British government. Up to now, companies have been able to price their drugs freely. But if the new policy is implemented, the U.K. will start ...

NYU Cancer Institute experts present at the AACR 102nd Annual Meeting 2011

2011-04-07
Experts from The Cancer Institute at NYU Langone Medical Center presented new research findings at the American Association for Cancer Research 102nd Annual Meeting 2011 held April 2-6, 2011 in Orlando, Florida. NYU Cancer Institute researchers discussed various breakthroughs such as a novel test for early-stage asbestos-related pulmonary cancer, a promising treatment strategy for glioblastomas, genome-wide mapping of nickel-related cancer and greater understanding of melanoma and bladder cancer. Detection of Mesothelioma in Asbestos Exposed Individuals with Aptamer ...

Trion:Z Announces Masters Tournament Active Series Contest

Trion:Z Announces Masters Tournament Active Series Contest
2011-04-07
To participate in the Trion:Z Masters Tournament giveaway contest, all you have to do is pick which of the three Rs is going to win. Trion:Z's triple threat; Rickie Fowler, Rory Mc Ilroy and Ryo Ishikawa - all will be competing for the coveted green jacket. Each possess the skill, talent, and drive to be the next Masters Champion. According to Reuters' Mark Lamport-Stokes, "Mc Ilroy long regarded as a future world #1 is probably the most spectacular member of the emerging generation to watch." However, Ishikawa is playing for the pride of Japan and is donating his 2011 ...

UPCI, Pitt researchers present findings of cancer studies at AACR 102nd Annual Meeting

2011-04-07
Orlando, Fla. – How do certain multiple myeloma treatment drugs cause complications? How does the immune system become dysfunctional due to cancer? How safe is a vaccine that could prevent development of precancerous colon polyps? Those are among the many questions that will be answered by researchers from the University of Pittsburgh Cancer Institute (UPCI) and the University of Pittsburgh School of Medicine during the American Association for Cancer Research 102nd Annual Meeting 2011, April 2 to 6, in Orlando, Fla. UPCI and Pitt researchers will present more than 80 ...

The Business Age is Discussed in This Month's Business Review India

The Business Age is Discussed in This Months Business Review India
2011-04-07
Welcome to the April issue of Business Review India! The Smartphone market in India is predictably growing and how! After all, with better browser speeds, affordable rates and a holistic user-friendly experience, the customer is lured into buying these palm-candies that promise oodles and fun and functionality. This issue of Business Review India helps buyers pick their ideal soul-Smartphone! Plus, discover how online chatting on social media is an untapped market that has lots to offer! Read this story to discover some essential secrets of this segment. Along with ...

Substance in tangerines fights obesity and protects against heart disease

2011-04-07
VIDEO: New research by Murray Huff, a vascular biology scientist with the University of Western Ontario has found a flavanoid in tangerines called Nobiletin not only prevents obesity, but also offers... Click here for more information. New research from The University of Western Ontario has discovered a substance in tangerines not only prevents obesity, but also offers protection against type 2 diabetes, and even atherosclerosis, the underlying disease responsible for most ...

Amount of AIDS virus in genital secretions predicts risk of heterosexual transmission

2011-04-07
Higher concentrations of the AIDS virus in genital secretions are linked to a greater risk of virus transmission between opposite-sex couples. The effect is independent of blood level of the virus. These findings will be reported in the April 7 edition of Science Translational Medicine, a publication of the American Association for the Advancement of Science. This is the first study to evaluate directly the relationship between genital concentrations of the HIV-1 virus and heterosexual transmission risk. The researchers demonstrated that high levels of HIV in mucus ...

Control the cursor with power of thought

2011-04-07
The act of mind reading is something usually reserved for science-fiction movies but researchers in America have used a technique, usually associated with identifying epilepsy, for the first time to show that a computer can listen to our thoughts. In a new study, scientists from Washington University demonstrated that humans can control a cursor on a computer screen using words spoken out loud and in their head, holding huge applications for patients who may have lost their speech through brain injury or disabled patients with limited movement. By directly connecting ...

iPhone, Blackberry or Droid: Finding the Right Smartphone For You, in Business Review India

iPhone, Blackberry or Droid: Finding the Right Smartphone For You, in Business Review India
2011-04-07
Three Smartphone giants are competing big time to offer the best user-friendly features. So how does one make the right choice? What is the most important feature in a Smartphone? E-mail usage, Internet browsing or tons of applications? Whatever the need, rest assured there is a Smartphone out there that now caters to every demand of the user! Authored by Pooja Thakkar, this special piece on Smartphones reveals how this market is growing in India and has something for everyone - whatever their budget may be. Read the full article, here.About Business Review India Business ...

Twitter & Facebook Marketing Tips in Business Review India

Twitter & Facebook Marketing Tips in Business Review India
2011-04-07
Social media represents a huge opportunity for established and emerging businesses across the world with Facebook and Twitter being top players in this field. Marketing on both these platforms offers businesses the possibility of exhibiting their product and services to an audience that is vast, anonymous yet intimately acquainted. It further allows the additional benefit of targeting the market based on age, region, race, income level among other factors. Tips in this article guide the reader to take optimum advantage of both these popular platforms. Read the full ...

South East Labels: a Greener Supply Chain

2011-04-07
A new report by the Confederation of British Industry describes changes in labeling as a 'win win for businesses and consumers' and one that will help the UK meet its carbon reduction targets. South East Labels welcomes the report with its endorsement of clear labeling policies as a vital part of commercial success and environmental gains. The report offers particular encouragement for SMEs, which can often be quicker to seize the initiative, to innovate and therefore to gain market share and status. The CBI report Buying into it: making the consumer case for low carbon ...

Structure formed by strep protein can trigger toxic shock

Structure formed by strep protein can trigger toxic shock
2011-04-07
VIDEO: M1 joints (red) and fibrinogen struts (blue) form a scaffold. Dense assemblies trigger a pathological response that can lead to toxic shock. Click here for more information. Infection with some strains of strep turn deadly when a protein found on their surface triggers a widespread inflammatory reaction. In a report published April 7 in the journal Nature, researchers describe the precise architecture of a superstructure formed when the bacterial protein called ...

Swiss Specialist Addresses Cell Society Members at Inaugural Scientific Summit in La Jolla

2011-04-07
Dr. Kai-Uwe Schlaudraff (www.concept-clinic.ch), a plastic surgeon who performs a wide range of plastic surgery procedures in Geneva, delivered a presentation on the topic of stem cell enriched fat transfer at the Cell Society's 1st Annual Clinical Meeting at the Estancia La Jolla Hotel & Spa in La Jolla, California. The meeting was held February 18 and 19, 2011. "The desire to know more about the use of stem and regenerative cells in cosmetic medicine is widespread," says Dr. Schlaudraff. "Practitioners, patients and policy-makers worldwide must take an educated approach ...

New fusion gene plays role in some stomach cancers

2011-04-07
DURHAM, N.C. – A newly discovered hybrid gene appears to play a direct role in some stomach cancers, according to an international team of scientists led by researchers at Duke-NUS Graduate Medical School Singapore. The hybrid gene is a fusion of two separate genes, and is one of the first described in gastric cancer, which is the most lethal malignancy worldwide after lung cancer. The disease kills an estimated 740,000 people a year, including nearly 11,000 annually in the United States. The gene discovery may one day give doctors a more effective way to use current ...

Ophthalmology Practice in San Luis Obispo Sponsors SLO Symphony's 50th Anniversary

Ophthalmology Practice in San Luis Obispo Sponsors SLO Symphonys 50th Anniversary
2011-04-07
Pacific Eye (www.paceyemd.com), the premier ophthalmology practice that provides optometry services in San Luis Obispo and Santa Barbara counties, continues to support the communities it serves with its sponsorship of the SLO Symphony's 50th anniversary season. Pacific Eye is known for providing comprehensive vision care services, including routine eye care, cataract surgery, and refractive surgical procedures including IntraLase LASIK in San Luis Obispo. In addition to their professional services, the practice is devoted to supporting their community. For example, ...

New Advance Website Features Improved Design to Facilitate Easy Product Selection by Product Type or Vertical Market

New Advance Website Features Improved Design to Facilitate Easy Product Selection by Product Type or Vertical Market
2011-04-07
Advance announces its new website with an enhanced structural design and efficient navigation tools for improved product selection and comprehensive service information. Providing a clean layout, the new website allows users to quickly access product information--including service manuals and parts list--by browsing various product categories or searching within multiple vertical markets. Featuring a simple navigation bar, users can easily locate Advance products or learn about Advance's comprehensive cleaning solutions, including its innovative EcoFlex System cleaning ...

MediaBoss Television Expands to Six Thousand Square Foot Studio

MediaBoss Television Expands to Six Thousand Square Foot Studio
2011-04-07
MediaBoss Television, a broadcast media, full creative, audio and video production company, announced today their expansion to a six thousand square foot facility in Framingham, Mass. MediaBoss Television provides the best digital content, creative services video and audio production to a variety of companies in the area like IBM, VGo Communications and Ipswitch, Inc. MediaBoss Television also produces local entertainment show, "Track Gals," which airs both on Boston CBS affiliate Channel 4 as well as WSBK's TV38. "The expansion of MediaBoss is a large step in achieving ...
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