The first study to examine the activity of hundreds of individual human brain cells during seizures has found that seizures begin with extremely diverse neuronal activity, contrary to the classic view that they are characterized by massively synchronized activity. The investigation by Massachusetts General Hospital (MGH) and Brown University researchers also observed pre-seizure changes in neuronal activity both in the cells where seizures originate and in nearby cells. The report will appear in Nature Neuroscience and is receiving advance online publication. "Our ...

Alpha viruses, such as Sindbis virus, carry their genetic information on a single strand of RNA. On infection they use a protein, replicase, to produce double stranded RNA (dsRNA) which is used as genetic material to make more viruses. However the body recognizes dsRNA as foreign, and infected cells initiate an immune response. New research published in BioMed Central's open access journal BMC Cancer demonstrates that an artificial plasmid coding for the replicase genes of Sindbis virus causes regression and destruction of lung cancer, or melanoma, cells in mice. Previous ...

Kidobi and MrsP.com announced today a new content distribution partnership, which adds Mrs. P Presents' titles The Tale of Peter Rabbit and The Princess and the Pea to Kidobi's growing library of digital videos for preschool-aged children. "Kidobi and Mrs P. share the same philosophy about providing an ad free and safe place for children to play and learn on the Internet," said Leo Henning, President of Kidobi. "We are proud to partner with MrsP.com, which received the American Library Association honor 'great site for kids'." Mrs. P, played by actress Kathy Kinney, ...

The immune system recognizes and neutralizes or destroys toxins and foreign pathogens that have gained access to the body. Autoimmune diseases result when the system attacks the body's own tissues instead. One of the most common examples is multiple sclerosis (MS). MS is a serious condition in which nerve-cell projections, or axons, in the brain and the spinal cord are destroyed as a result of misdirected inflammatory reactions. It is often characterized by an unpredictable course, with periods of remission being interrupted by episodes of relapse. A team of researchers ...

The earliest rocks in our Solar System were more like candy floss than the hard rock that we know today, according to research published today in the journal Nature Geoscience. The work, by researchers from Imperial College London and other international institutions, provides the first geological evidence to support previous theories, based on computer models and lab experiments, about how the earliest rocks were formed. The study adds weight to the idea that the first solid material in the Solar System was fragile and extremely porous – much like candy floss – and ...

LA JOLLA, CA – Over the last years, two teams of researchers at The Scripps Research Institute have steadily built a model of how a powerful DNA repair complex works. Now, their latest discovery provides revolutionary insights into the way the molecular motor inside the complex functions – findings they say may have implications for treatment of disorders ranging from cancer to cystic fibrosis. In a paper published in an Advance Online Edition of Nature Structural and Molecular Biology March 27, 2011, the scientists say that the complex's motor molecule, known as Rad50, ...

SALT LAKE CITY, March 28, 2011 – University of Utah scientists used invisible infrared light to make rat heart cells contract and toadfish inner-ear cells send signals to the brain. The discovery someday might improve cochlear implants for deafness and lead to devices to restore vision, maintain balance and treat movement disorders like Parkinson's. "We're going to talk to the brain with optical infrared pulses instead of electrical pulses," which now are used in cochlear implants to provide deaf people with limited hearing, says Richard Rabbitt, a professor of bioengineering ...

A Canadian online slots player has won a $165,900 progressive jackpot at WinADayCasino.com. Sylvia M., known as POWERBALL on the site, won the massive jackpot playing the Tropical Treat slot machine, one of the online casino's newest flash technology games with enhanced full-screen graphics and rich sound effects. "The progressive jackpot can be won on any of our online slots," said Michael Hilary, manager of the slots and video poker site. "But since it's been the Game of the Month for March and has been played more than usual over the last few weeks, I guess it's ...

Researchers at the University of California, San Diego School of Medicine claim that the availability of surgeons is a critical factor in public health and suggest that surgery should become an important part of the primary health care system. A recent study led by David C. Chang, PhD, MPH, MBA, director of Outcomes Research in the Department of Surgery at UCSD School of Medicine, points out that surgery in the United States continues to be seen as tertiary care and is mainly centered at large urban hospitals, creating an unequal distribution of surgical providers. The ...

New research documenting changes in the incidence and outcomes of end-stage renal disease (ESRD) in the U.S. between 1995 and 2006, found a significant increase in incidence rates among patients 5 to 39 years of age and in African Americans. A second related study—the largest pediatric lupus nephritis-associated ESRD study to date—revealed high rates of adverse outcomes among children with ESRD due to lupus nephritis. Despite novel therapies, outcomes have not improved in over a decade. Both studies now appear online in Arthritis & Rheumatism, a journal published by Wiley-Blackwell ...

A new study has found that certain types of women with early stage breast cancer are vulnerable to excessive worrying about cancer recurrence. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study also indicates that worrying about cancer recurrence can compromise patients' medical care and quality of life. Thanks to recent medical advances, most women who are diagnosed with early stage breast cancer have a low risk for cancer recurrence. Despite an optimistic future, many of these women report that they worry that their ...

ANN ARBOR, Mich. — Most women face only a small risk of breast cancer coming back after they complete their treatment. Yet a new study from the University of Michigan Comprehensive Cancer Center finds that nearly half of Latinas who speak little English expressed a great deal of worry about recurrence. "Some worry about cancer recurrence is understandable. But for some women, these worries can be so strong that they impact their treatment decisions, symptom reporting and screening behaviors, and overall quality of life," says study author Nancy K. Janz, Ph.D., professor ...

Leading Australian online casino, Casino Aus, is due to release a highly unique Asian-themed video slot game on 7 April 2011. Asian Beauty Video Slot is a 5 Reel, 243 Way Video Slot that encapsulates the mystic surrealism that surrounds Asian Royalty. 3 or more of the master-crafted treasure chests across the reels act as the Scatter in this game, launching between 10 and 25 retriggering Free Spins which double all wins. These Scatter pays are multiplied by the players total bet and can also be generous as they range between 5x to 100x total bet. The emperor's daughters ...

Looking to spice up your sex life? Try adding ginseng and saffron to your diet. Both are proven performance boosters, according to a new scientific review of natural aphrodisiacs conducted by University of Guelph researchers. Indulge in wine and chocolate, too, but know that their amorous effects are likely all in your head. Stay away from the more obscure Spanish fly and Bufo toad. While purported to be sexually enhancing, they produced the opposite result and can even be toxic. Those are among the findings of the study by Massimo Marcone, a professor in Guelph's Department ...

Sheraton Atlanta Perimeter Hotel North, located near Perimeter Mall and Dunwoody, GA, recently announced a new special savings deal for spring travelers to enjoy. Guests who book their stay by April 4 can get room ratings starting at $69 per night. The deal is available for stays Thursday through Sunday, March 31 through May, 30, 2011. The Sheraton Atlanta Perimeter Hotel's services and amenities include: - Free High-speed Internet Access - Club level lounge - Concierge desk - Complimentary 24-hour Fitness Facility and jogging path - Guest rooms with Sheraton Sweet ...

The disaster in Japan has the world's attention. Millions of people watch in horror as the people of Japan struggle to get through day by day. Japan suffered a 1-2-3 punch in the events of an earthquake, then a tsunami, and finally nuclear radiation worries. Many different teams of rescuers have been sent over to Japan to aid in the search and rescue efforts. These teams have been tasked with the responsibility to search for both survivors and bodies in various towns and villages along the east coast of Japan. What has become an almost requirement for these teams are tools ...

New Website Launched to Clear Up the Confusion Surrounding Oil and Gas Investing A brand new website is being launched that is designed to help clear up the misconceptions that continue to exist regarding oil and gas investing. OilandGasPartnerships.net is a rich source of well researched, professionally developed, ethical information about investing in oil and gas through partnerships. For those well qualified investors who have been looking for reliable information not colored by high pressure sales or unethical promises of guaranteed results, Oil and Gas Partnerships ...

Figuring out whether or not file taxes and how to file is confusing enough. When the IRS decides you owe money when you know you don't - that just gets plain stressful! Take Steve (Alameda, CA), for instance, who came to Blue Tax after being harassed by the IRS and State because of a mistake made by his daughter's mortgage lender. Steve's daughter was receiving funds from a malpractice lawsuit, which was the basis of her income. Her mortgage lender was supposed to reference that income in their records but instead mistakenly applied it as Steve's income. The goal ...

Swinglifestyle is teaming up with Topless travel to bring a fun filled night of adventure for swingers at Caliente Resort in Tampa, FL. Swinglifestyle has generously secured an 80% discount for people wanting a day pass and an extra 15% off the rooms. Caliente is known as probably the most high-class clothing optional encounters imaginable. Enjoy the SLS member meet and greet in the Club House Lobby between 8-9pm on April 9th. Couples are asked to enter a contest for a chance to receive a 4 day Caribbean Resort Give away and gain access to the Exclusive SLS after party. ...

Fleet Enterprises, a fleet maintenance company that provides mobile repair and maintenance services to the transportation industry, announced today that it has sold a second franchise to Wes Yonkman in Flint, Michigan, as it continues to expand its presence into the Central region of the United States. The franchised business is expected to begin operations within the next two months, and joins the growing network of Fleet Enterprises franchised locations. "We're pleased to have Wes on our team," said Darin Gross, Co-Owner of Fleet Enterprises. "His background and experience ...

Advanced Modern Technologies Corporation (AMTC) is pleased to announce today the introduction of the FixedFlo(TM) automatic faucet system, the industry's first non-adjustable, internally-controlled water saving faucet. AMTC's patent pending FixedFlo(TM) mechanism is designed to flow at its rated gallons per minute regardless of variations in water pressure or aerator utilized. The FixedFlo(TM) comes in a non-adjustable 0.4gpm, 0.5gpm and 1.0gpm water flow models. "The FixedFlo(TM) Faucet is the first commercial faucet that is guaranteed to deliver years of maintenance ...

The Dana Point Community Cycling Foundation in partnership with Amgen's Breakaway From Cancer initiative is hosting a premiere event on Saturday, April 30, 2011 from 6pm-8pm at The Dana Point Yacht Club, preceding the nationally recognized Dana Point Grand Prix of Cycling in downtown Dana Point on Sunday, May 1st. The evening's ticket includes food, drinks, entertainment and a fabulous silent auction. Proceeds from this year's event directly benefit Amgen's Breakaway From Cancer and the Pacific Meso Center (PMC) at Pacific Heart, Lung & Blood Institute in Los Angeles. Space ...

EnsuranceEZ.com announces the launch of their website (http://www.ensuranceez.com/), designed to help make purchasing and learning about insurance easy for their clients. Visitors will be able to obtain quotes online for a wide number of products, each one displaying comparison quotes from most of the leading insurers in their state. The various products include car insurance, home insurance, life and health insurance. Every year more consumers are turning to the internet to find a solution to their insurance needs. Initially people would only use the internet to purchase ...

While other comics are busy knocking on doors asking for work, award-winning comedian Don Barnhart is making his own opportunities and creating work for himself and fellow comedians large and small. From producing and performing comedy shows for the troops around the world to headlining the top comedy clubs across the country, Barnhart is now starring in his own show nightly in Las Vegas, NV. The Don Barnhart Comedy Show opens at The Star Theater (Formerly The Debbie Reynolds Theater) at The Clarion Hotel (Formerly Greek Isles) April 12, 2011 providing laughter every ...

Marketing Intelligence Media presents a Social Media Marketing Event. This event will cover the main aspects of social media marketing and the importance of utilizing the best practices and platforms for your category of business. Not every business is suitable for social marketing and while many companies offer a cookie cutter approach, MIM9 will shed light on which approach is best for your industry, or if Social Media Marketing is the right choice for your business at all. Industry veteran, Vaagn Arakelyan, will present this April 13th event. With over 14 years in ...