ROCHESTER, Minn. -- The drug pazopanib may help revolutionize the care of patients with metastatic, rapidly progressive differentiated thyroid cancers, say researchers at Mayo Clinic who are publishing findings of a phase II clinical trial in The Lancet Oncology. VIDEO ALERT: Additional audio and video resources, including excerpts from an interview with Dr. Keith Bible describing the research, are available on the Mayo Clinic News Blog. Password: bible. The researchers studied 37 patients with the most aggressive form of this cancer -- developing in less than 5 percent ...

WASHINGTON — The nation's ability to detect and forecast tsunamis has improved since the 2004 Indian Ocean tsunami, but current efforts are still not sufficient to meet challenges posed by tsunamis generated near land that leave little time for warning, says a new congressionally requested report from the National Research Council. The report calls for a comprehensive national assessment of tsunami risk and improved communication and coordination among the two federal Tsunami Warning Centers, emergency managers, media, and the public. "For a tsunami warning system ...

PHILADELPHIA - The lab of Kevin Foskett, PhD, the Isaac Ott Professor of Physiology at the University of Pennsylvania School of Medicine, has found a possible new target for fighting cystic fibrosis (CF) that could compensate for the lack of a functioning ion channel in affected CF-related cells. Their finding appears in the Journal of Clinical Investigation. The team explored the role of CFTR, the chloride ion channel mutated in CF patients, in fluid secretion by mucous gland cells. They used a recently developed transgenic pig model, in which the CFTR gene has been ...

TORONTO, September 17, 2010 – Nearly half of women with diabetes prior to pregnancy have a potentially-avoidable C-section and their babies are twice as likely to die as those born to women without diabetes, according to the POWER study. Researchers from St. Michael's Hospital, the Institute for Clinical Evaluative Sciences (ICES) and Women's College Hospital say rates of diabetes in Ontario have doubled in the last 12 years. Nearly one in 10 Ontario adults has been diagnosed with diabetes, including more women than ever before. As women develop type 2 diabetes (adult ...

Global efforts to tackle millions of preventable child and maternal deaths will fail to extend gains unless world leaders act now to pour more healthcare resources directly into families and communities, according to a new World Vision report launched today. "The Missing Link: Saving children's lives through family care" examines how the resources invested to achieve Millennium Development Goals (MDGs) 4 and 5 can go further toward saving the more than 8 million children under the age of five and 350,000 mothers who die each year, mostly from preventable causes. Undertaken ...

Infrared satellite data from NASA's Aqua satellite revealed strong convection and a tight circulation center within Typhoon Fanapi as it heads for a landfall in Taiwan this weekend. At 1500 UTC (10 a.m. EDT) on Sept. 17, Typhoon Fanapi's maximum sustained winds were near 85 knots (97 mph). It was centered about 360 nautical miles east-southeast of Taipei, Taiwan near 23.2 North and 127.4 East. It is churning up high seas up to 22 feet. NASA's Aqua satellite passed over Typhoon Fanapi on September 17 at 04:45 UTC (12:45 a.m. EDT) and captured an infrared image of its ...

We run our modern lives largely by the clock, from the alarms that startle us out of our slumbers and herald each new workday to the watches and clocks that remind us when it's time for meals, after-school pick-up and the like. In addition to those ubiquitous timekeepers, though, we have internal "clocks" that are part of our biological machinery and which help set our circadian rhythms, regulating everything from our sleep-wake cycles to our appetites and hormone levels. Light coming into our brains via our eyes set those clocks, though no one is sure exactly how this ...

NASA's CloudSat satellite captured a profile of Hurricane Karl as it began making landfall in Mexico today. The satellite data revealed very high, icy cloud tops in Karl's powerful thunderstorms, and moderate to heavy rainfall from the storm. Meanwhile, NASA's "GRIP" mission was also underway as aircraft were gathering valuable data about Hurricane Karl as he moves inland. NASA's Genesis and Rapid Intensification Processes mission (known as GRIP) is still underway and is studying the rapid intensification of storms, and that's exactly what Karl did on Thursday Sept. ...

Julia is waning in the eastern Atlantic Ocean because of outflow from massive Hurricane Igor, despite his distance far to the west. Satellite imagery from NASA's Aqua satellite showed that Julia's eye was no longer visible, a sign that she's weakening. As NASA's Aqua satellite flew over Hurricane Julia from space on Sept. 16 at 1:35 p.m. EDT, the Moderate Resolution Imaging Spectroradiometer (MODIS) instrument captured a visible image of the storm. In the MODIS image, Julia's eye was no longer visible and its center was cloud-filled. Although Julia is weakening from ...

Spoilage bacteria that can cause red coloration of pickles' skin during fermentation may actually help clean up dyes in textile industry wastewater, according to a U.S. Department of Agriculture (USDA) study. Some species of Lactobacilli-food-related microorganisms-can cause red coloring when combined with tartrazine, a yellow food-coloring agent used in the manufacture of dill pickles. Now Agricultural Research Service (ARS) microbiologist Ilenys Pérez-Díaz and her colleagues have found that these spoilage Lactobacilli also may have environmental benefits. ARS is ...

Deleting a certain gene in mice can make them smarter by unlocking a mysterious region of the brain considered to be relatively inflexible, scientists at Emory University School of Medicine have found. Mice with a disabled RGS14 gene are able to remember objects they'd explored and learn to navigate mazes better than regular mice, suggesting that RGS14's presence limits some forms of learning and memory. The results were published online this week in the Early Edition of the Proceedings of the National Academy of Sciences. Since RGS14 appears to hold mice back mentally, ...

Solar energy could be a central alternative to petroleum-based energy production. However, current solar-cell technology often does not produce the same energy yield and is more expensive to mass-produce. In addition, information on the total effect of solar energy production on the environment is incomplete, experts say. To better understand the energy and environmental benefits and detriments of solar power, a research team from Rochester Institute of Technology has conducted one of the first life-cycle assessments of organic solar cells. The study found that the embodied ...

Traumatic brain injury (TBI) is a serious public health problem in the United States. Recent data show that approximately 1.7 million people sustain a traumatic brain injury annually. While the majority of TBIs are concussions or other mild forms, traumatic brain injuries contribute to a substantial number of deaths and cases of permanent disability. Currently, there are no drugs available to treat TBI: a variety of single drugs have failed clinical trials, suggesting a possible role for drug combinations. Testing this hypothesis in an animal model, researchers at SUNY ...

Salt Lake City, September 17, 2010—Colon cancer is the second most common cancer in the United States and causes more than 50,000 deaths each year. It has been known for some time that mutations in the APC gene occur in more than 85 percent of all sporadic colon cancers. Now researchers at Huntsman Cancer Institute at the University of Utah demonstrate in a study featured today in Cell the mechanism by which mutation of the APC gene affects a cellular process known as DNA methylation. DNA methylation is a chemical modification made to DNA that plays an important role in ...

ANN ARBOR, Mich.---How could climate change and our response to it affect the Great Lakes' water quality? That's the primary question a team of 27 researchers from across the University of Michigan and collaborators at other institutions will answer with a new $5-million grant from the National Science Foundation. The researchers will focus on extreme weather events caused by climate change. The Great Lakes hold 84 percent of North America's surface fresh water, and their basin is home to 10 percent of the U.S. population. "The suspicion is that climate change will ...

Calling all cooks! You may think you know all there is to know about making pizza and chicken parmigiana, but Aussie chef Mick Reade has written a new cookbook that will creatively challenge your preconceived ideas about these two dishes. The 2001 winner of Australia's Best Steak Cooker title has now published a cookbook full of mouth watering variations on chicken parmigiana and pizza Recipes. In his self published title, Pizzas and Parmas - The Possibilities Are Endless, Chef Reade shares some of the creative and unusual recipes he has used over the past 12 years as ...

NAPMA, the National Association of Professional Martial Artists, the business trade association for martial arts schools, martial arts school owners, and professional martial arts instructors is hosting the 2010 NAPMA "Extreme Success Academy", featuring top industry expert speakers, and the world renown business and entrepreneurial expert Mr. Brian Tracy! Some seminars, events, conferences and shows are a bit like Chinese food...you like it while you eat it, but you're hungry half an hour later, feeling deflated and unsatisfied. Members have been telling us for years, ...

If you've ever wished you could learn more about the Planet of the Apes mythos... if you've devoured the films and TV series, but have never read the comic books or novels that continued their story... if you're tantalized by time travel and titillated by trivia... if you think you know all there is to know about simian society... then Lexicon of the Planet of the Apes is meant for you. This staggeringly complete lexicon from Hasslein Books, written by Timeline of the Planet of the Apes author Rich Handley and designed by Paul C. Giachetti, will contain: * Nearly ...

An extraordinary mahogany "Beau Brummel" dressing table fit for a princess has swept into the spotlight of Austin Auction's Sept. 25-26 Estate Auction. The circa-1930 triple-mirrored dressing table is of the highest-quality construction and is fitted with a key-lock safe and exquisite 30-piece Art Deco vanity set of sterling silver and cut glass. The well-marked table and its accessories were crafted by the premier London firm Goldsmiths & Silversmiths Co. Ltd. Each hallmarked vanity accessory is finely enameled and adorned with an Islamic moon-and-star motif as ...

Ciena Healthcare Management, the largest privately owned manager and operator of skilled nursing and rehabilitation facilities in Michigan, announces the opening of its new $1 million Cardiac Rehab Unit at the Hartford Nursing and Rehabilitation Center in Detroit. The announcement was made by Ciena Healthcare President Mohammad Qazi. The Cardiac Rehab Unit, the first specialty unit in Detroit to focus exclusively on cardiac care, is housed on the newly renovated third floor of Ciena's Hartford community and consists of 12 beds and an exercise area, all within a 5,723 ...

The CTO Telecom Summit team announced today that Microsoft and Intel will deliver keynote presentations at the upcoming technology event, to be held October 3-6, 2010 at the JW Marriott Camelback Inn, Scottsdale, Arizona. The CTO Telecom Summit is an opportunity for CTOs, CIOs and IT executives to network and participate in a strategically planned agenda. Attendees have the opportunity to attend think-tank sessions, vision panels, keynote presentations, and case studies that examine the most recent technology developments within the telecom industry. Harry Patz, VP, ...

Within these assets there are inherent operational inefficiencies that can cost millions in unnecessary annual supply chain costs. Simplifying Complex Supply Chain Challenges Supply Chains have become more and more complex, but the end goal is still the same: give your customers what they want when they want it. To solve this key supply chain challenge, Blue Sky has developed the Perfect Order Insight module which will help you deliver the right amount of the right product at the right time by letting you track service level metrics by factors such as customer, ...

BALAM Dance Theatre (BALAM) presents "The Melon Peel", an authentic and hilarious Commedia dell'Arte monologue, at the 2010 DUMBO DANCE FESTIVAL, 25 Jay Street, Brooklyn, New York on Sunday, September 26, 2010, from 5-6 p.m. The festival is open and FREE to the public. BALAM creates a new vision of contemporary dance by fusing Balinese theatre and diverse cultural movement styles from around the world. "The Melon Peel" features Inma Heredia, BALAM's resident guest actor, in this bawdy monologue created with period gestures and choreography by BALAM's artistic director, ...

SmartAVI, Inc., a world-leading innovator in the fields of digital signage content creation, management and delivery solutions through hardware and software, announces the release of its SignWare digital signage solution. SignWare is a comprehensive digital signage package that is very affordable and fully expandable. It is manageable from any location on the planet, and despite its small size it is expandable from one to one thousand signage installations. SignWare offers crisp high-definition 720p/1080i HDTV video combined with stereo audio in a conveniently low-profile ...

Canonical Ltd., the commercial sponsor of Ubuntu, unveiled the a list of provisional tracks for the Ubuntu Developer Summit (UDS) scheduled for October 25-29, 2010 in Orlando, Florida. To be confirmed, along with more announced, in coming weeks, the tracks were made available today on the newly-launched UDS site, http://uds.ubuntu.com/. The site is a destination for information about the event for the key participants in Ubuntu's development, from Canonical engineers and community members to ISVs and partners. "UDS is a chance to bring all of the contributors to Ubuntu ...