The mechanism for binding oxygen to metalloporphyrins is a vital process for oxygen-breathing organisms. Understanding how small gas molecules are chemically bound to the metal complex is also important in catalysis or the implementation of chemical sensors. When investigating these binding mechanisms, scientists use porphyrin rings with a central cobalt or iron atom. They coat a copper or silver support surface with these substances. An important characteristic of porphyrins is their conformational flexibility. Recent research has shown that each specific geometric configuration ...

Instances of cyber bullying continue to make news nearly every day, and while it's recognized as a problem among most school-aged children, a new study published this month in Children & Schools and coauthored by Temple University social work professor Jonathan Singer finds that nearly half of school social workers feel they are ill equipped to handle it. "School social workers provide more crisis intervention services than any other school staff member – more than counselors, nurses, teachers, or psychologists," said Singer. "As a result, school social workers are a ...

VIDEO: Researchers at Rensselaer Polytechnic Institute have developed liquid pistons, which can be used to precisely pump small volumes of liquid. Comprising the pistons are droplets of nanoparticle-infused ferrofluids, which can... Click here for more information. Troy, N.Y. – A few unassuming drops of liquid locked in a very precise game of "follow the leader" could one day be found in mobile phone cameras, medical imaging equipment, implantable drug delivery devices, ...

Researchers at Nationwide Children's Hospital report a gene therapy strategy that improves the condition of a mouse model of an inherited blood disorder, Beta Thalassemia. The gene correction involves using unfertilized eggs from afflicted mice to produce a batch of embryonic stem cell lines. Some of these stem cell lines do not inherit the disease gene and can thus be used for transplantation-based treatments of the same mice. Findings could hold promise for a new treatment strategy for autosomal dominant diseases like certain forms of Beta Thalassemia, tuberous sclerosis ...

Using biological samples taken from patients and state-of-the-art biochemical techniques, a Florida State University researcher is working to identify a variety of "biomarkers" that might provide earlier warnings of the presence of breast and prostate cancers. "Biomarkers are indicators of certain biological and pathological processes that are occurring, such as cancer," said Qing-Xiang "Amy" Sang, a professor in Florida State's Department of Chemistry and Biochemistry. "Either the cancer cells themselves, or surrounding normal tissue for that matter, can produce specific ...

UCLA researchers have found that a protein that plays an important role in some antioxidant therapies may not be as effective due to additional mechanisms that cause it to promote atherosclerosis, or clogging of the arteries. Published in the January issue of the journal Arteriosclerosis, Thrombosis and Vascular Biology, the finding may give clues as to why some antioxidant therapies have not yielded more positive results. The protein, called Nrf2, has been thought to be an important drug-therapy target for diseases such as cancer because it can induce chemopreventive ...

Persistence paid off for a University of Alberta paleontology researcher, who after months of pondering the origins of a fossilized jaw bone, finally identified it as a new species of pterosaur, a flying reptile that lived 70 million years ago. Victoria Arbour says she was stumped when the small piece of jaw bone was first pulled out of of a fossil storage cabinet in the U of A's paleontology department. "It could have been from a dinosaur, a fish or a marine reptile," said Arbour. " Arbour, a PhD student in paleontology, says the first clue to the fossil's identify ...

Glass stronger and tougher than steel? A new type of damage-tolerant metallic glass, demonstrating a strength and toughness beyond that of any known material, has been developed and tested by a collaboration of researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab)and the California Institute of Technology. What's more, even better versions of this new glass may be on the way. "These results mark the first use of a new strategy for metallic glass fabrication and we believe we can use it to make glass that will be even ...

Washington, D.C. — Sophisticated tools allow scientists to subject the basic elements of matter to conditions drastic enough to modify their behavior. By doing this, they can expand our understanding of matter. A research team including three Carnegie scientists was able to demonstrate surprising properties of the element lithium under intense pressure and low temperatures. Their results were published Jan. 9 on the Nature Physics website. Lithium is the first metal in the periodic table and is the least dense solid element at room temperature. It is most commonly known ...

DURHAM, N.H. – An international team of researchers, including several from the University of New Hampshire, have completed the first DNA sequence of any strawberry plant, giving breeders much-needed tools to create tastier, healthier strawberries. Tom Davis, professor of biological sciences at UNH, and postdoctoral researcher Bo Liu were significant contributors to the genome sequence of the woodland strawberry, which was published last month in the journal Nature Genetics. "We now have a resource for everybody who's interested in strawberry genetics. We can answer questions ...

NJIT Distinguished Professor Philip R. Goode and the research team at Big Bear Solar Observatory (BBSO) have reported new insights into the small-scale dynamics of the Sun's photosphere. The observations were made during a period of historic inactivity on the Sun and reported in The Astrophysical Journal . http://iopscience.iop.org/2041-8205/714/1/L31 The high-resolution capabilities of BBSO's new 1.6-meter aperture solar telescope have made such work possible. "The smallest scale photospheric magnetic field seems to come in isolated points in the dark intergranular ...

PROVIDENCE, R.I. [Brown University] — In the longest-term study so far to track people with body dysmorphic disorder, a severe mental illness in which sufferers obsess over nonexistent or slight defects in their physical appearance, researchers at Brown University and Rhode Island Hospital found high rates of recovery, although recovery can take more than five years. The results, based on following 15 sufferers of the disease over an eight-year span, appear in the current issue of the Journal of Nervous and Mental Disease. "Compared to what we expected based on a prior ...

In recent years, developers have been investigating light-harvesting thin film solar panels made from nanotechnology –– and promoting efficiency metrics to make the technology marketable. Now a Tel Aviv University researcher is providing new evidence to challenge recent "charge" measurements for increasing solar panel efficiency. Offering a less expensive, smaller solution than traditional panels, Prof. Eran Rabani of Tel Aviv University's School of Chemistry at the Raymond and Beverly Sackler Faculty of Exact Sciences puts a lid on some current hype that promises to ...

A new study conducted by Josh LaBaer's research team in the Biodesign Institute at Arizona State University has pinpointed more than 30 breast cancer gene targets ---including several novel genes---that are involved in drug resistance to a leading chemotherapy treatment. The results of the study may one day aid in the treatment of the one in ten U.S. women who will develop breast cancer, by empowering physicians with a more personalized approach to therapy as well as a new tool for the early screening of those that may ultimately become resistant to chemotherapy. Drugs ...

CHAMPAIGN, Ill. — Using detailed land analysis, Illinois researchers have found that biofuel crops cultivated on available land could produce up to half of the world's current fuel consumption – without affecting food crops or pastureland. Published in the journal Environmental Science and Technology, the study led by civil and environmental engineering professor Ximing Cai identified land around the globe available to produce grass crops for biofuels, with minimal impact on agriculture or the environment. Many studies on biofuel crop viability focus on biomass yield, ...

University of Illinois research reports that several herbicides used on corn also have good selectivity to Miscanthus x giganteus (Giant Miscanthus), a potential bioenergy feedstock. "No herbicides are currently labeled for use in Giant Miscanthus grown for biomass," said Eric Anderson, an instructor of bioenergy for the Center of Advanced BioEnergy Research at the University of Illinois. "Our research shows that several herbicides used on corn are also safe on this rhizomatous grass." M. x giganteus is sterile and predominantly grown by vegetative propagation, or planting ...

WEST LAFAYETTE, Ind. - Large hypoxic zones low in oxygen long have been thought to have negative influences on aquatic life, but a Purdue University study shows that while these so-called dead zones have an adverse affect, not all species are impacted equally. Tomas Höök, an assistant professor of forestry and natural resources, and former Purdue postdoctoral researcher Kristen Arend used output from a model to estimate how much dissolved oxygen was present in Lake Erie's hypoxic zone each day from 1987 to 2005. That information was compared with biological ...

AUSTIN, Texas — Growing up poor can suppress a child's genetic potential to excel cognitively even before the age of 2, according to research from psychologists at The University of Texas at Austin. Half of the gains that wealthier children show on tests of mental ability between 10 months and 2 years of age can be attributed to their genes, the study finds. But children from poorer families, who already lag behind their peers by that age, show almost no improvements that are driven by their genetic makeup. The study of 750 sets of twins by Assistant Professor Elliot ...

University of California, Berkeley, astronomers may have found the missing link between gas-filled, star-forming galaxies and older, gas-depleted galaxies typically characterized as "red and dead." In a poster to be presented this week at the American Astronomical Society meeting in Seattle, UC Berkeley astronomers report that a long-known "early-type" galaxy, NGC 1266, is expelling molecular gas, mostly hydrogen, from its core. Astronomers have long recognized the distinction between early-type red and dead galaxies, thought to be largely devoid of gas and dust and ...

RIVERSIDE, Calif. – Geologists at the University of California, Riverside have found chemical evidence in 2.6-billion-year-old rocks that indicates that Earth's ancient oceans were oxygen-free and, surprisingly, contained abundant hydrogen sulfide in some areas. "We are the first to show that ample hydrogen sulfide in the ocean was possible this early in Earth's history," said Timothy Lyons, a professor of biogeochemistry and the senior investigator in the study, which appears in the February issue of Geology. "This surprising finding adds to growing evidence showing ...

It is well known that pain is a highly subjective experience. We each have a pain threshold, but this can vary depending on distractions and mood. A paper in the International Journal of Behavioural and Healthcare Research offers a cautionary note on measuring perceived pain in research. There are many chronic illnesses and injuries that have no well-defined symptoms other than pain, but because of the subjectivity in a patient's reporting of their experience of the illness or injury, healthcare workers have difficulty in addressing the patient's needs. Moreover, when ...

People have only 20,000 to 30,000 genes (the number is hotly contested), but they use those genes to make more than 2 million proteins. It's the protein molecules that domost of the work in the human cell. After all, the word protein comes from the Greek prota, meaning "of primary importance." Proteins are created as chains of amino acids, and these chains of usually fold spontaneously into what is called their "native form" in milliseconds or a few seconds. A protein's function depends sensitively on its shape. For example, enzymes and the molecules they alter are ...

CHICAGO --- One out of every four or five students who visits a university health center for a routine cold or sore throat turns out to be depressed, but most centers miss the opportunity to identify these students because they don't screen for depression, according to new Northwestern Medicine research. About 2 to 3 percent of these depressed students have had suicidal thoughts or are considering suicide, the study found. "Depression screening is easy to do, we know it works, and it can save lives," said Michael Fleming, professor of family and community medicine ...

In the vast ocean where an essential nutrient—iron—is scarce, a marine bacterium that launches the ocean food web survives by using a remarkable biochemical trick: It recycles iron. By day, it uses iron in enzymes for photosynthesis to make carbohydrates; then by night, it appears to reuse the same iron in different enzymes to produce organic nitrogen for proteins. The bacterium, Crocosphaera watsonii, is one of the few marine microbes that can convert nitrogen gas into organic nitrogen, which (just as it does on land) acts as fertilizer to stimulate plant growth in ...

When their romantic partners are not quintessentially masculine, women in their fertile phase are more likely to fantasize about masculine-looking men than are women paired with George Clooney types. But women with masculine-looking partners do not necessarily become more attracted to their partners, a recent study co-authored by a University of Colorado at Boulder researcher concludes. Meanwhile, a man's intelligence has no effect on the extent to which fertile, female partners fantasize about others, the researchers found. They say the lack of an observed "fertility ...