PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Osteoarthritis and the (not so) painful step toward a cure

2013-09-17
(Press-News.org) On Tuesday, September 17, JoVE, the Journal of Visualized Experiments, will publish a novel technique for imaging muscle function while in motion. Research in this area could uncover the root of musculoskeletal disorders, such as the development of osteoarthritis following ACL surgery.

"The technique uses ultrasound waves to detect the motion of muscles using the Doppler principle," said the lab's principal investigator Dr. Siddhartha Sikdar, "We use a stereo method, where ultrasound waves from multiple directions are combined ... with a number of other biomechanical measurements of joint movement."

When used simultaneously, the data collected by this method provides Dr. Sikdar's team a detailed look at the multiple aspects of human movement involved in preforming a dynamic task — for example, "how much force is being applied at the knee, and how much muscle is working," said Dr. Sikdar.

VIDEO: In this video, JoVE details Dr. Sikdar's novel application of musculoskeletal ultrasound Imaging.
Click here for more information.

And while the individual techniques themselves are not new, the combination of information from ultrasound and several other procedures such as 3D motion capture is altogether a unique and promising idea. "We believe that this integrated approach can help us better understand the underlying causes of osteoarthritis development," said Dr. Sikdar. He hypothesizes that the development of osteoarthritis is due to abnormal forces acting on the knee, leading to injury and degeneration.

"Once these abnormalities are identified, targeted intervention programs can be implemented to correct for these abnormalities," said Dr. Sikdar, "Further, we can also do subject-specific models based on actual data rather than using animal or cadaveric data."

JoVE will publish Sikdar's article alongside a video reconstruction of the experiment to ensure its reproducibility. "The ability to use video to demonstrate the methods is definitely a great advantage of this journal," said Dr. Sikdar.



INFORMATION:



About JoVE, the Journal of Visualized Experiments:

JoVE, the Journal of Visualized Experiments, is the first and only PubMed/MEDLINE-indexed, peer-reviewed journal devoted to publishing scientific research in a video format. Using an international network of videographers, JoVE films and edits videos of researchers performing new experimental techniques at top universities, allowing students and scientists to learn them much more quickly. JoVE has published video-protocols from an international community of nearly 8,000 authors in the fields of biology, medicine, chemistry, and physics.



ELSE PRESS RELEASES FROM THIS DATE:

NIH-funded study suggests brain is hard-wired for chronic pain

2013-09-17
The structure of the brain may predict whether a person will suffer chronic low back pain, according to researchers who used brain scans. The results, published in the journal Pain, support the growing idea that the brain plays a critical role in chronic pain, a concept that may lead to changes in the way doctors treat patients. The research was supported by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health. "We may have found an anatomical marker for chronic pain in the brain," said Vania Apkarian, Ph.D., ...

Study upholds hyaluronic acid injection safety, efficacy profile in reducing knee OA pain

2013-09-17
Raleigh-Durham, NC. -- A new meta-analysis of 29 randomized studies involving more than 4,500 patients with knee osteoarthritis (OA) found that intra-articular hyaluronic acid (HA) injections provided significant improvement in pain and function compared to saline injections. The study, "US-Approved Intra-Articular Hyaluronic Acid Injections are Safe and Effective in Patients with Knee Osteoarthritis: Systematic Review and Meta-Analysis of Randomized, Saline-Controlled Trials," was published online this month in Clinical Medicine Insights: Arthritis and Musculoskeletal ...

Carbonation alters the mind's perception of sweetness

2013-09-17
Bethesda, MD -- Carbonation, an essential component of popular soft drinks, alters the brain's perception of sweetness and makes it difficult for the brain to determine the difference between sugar and artificial sweeteners, according to a new article in Gastroenterology, the official journal of the American Gastroenterological Association. "This study proves that the right combination of carbonation and artificial sweeteners can leave the sweet taste of diet drinks indistinguishable from normal drinks," said study author, Rosario Cuomo, associate professor, gastroenterology, ...

Racism linked to depression and anxiety in youth

2013-09-17
The first of its kind, the review showed 461 cases of links between racism and child and youth health outcomes. Lead researcher Dr Naomi Priest at the McCaughey VicHealth Centre for Community Wellbeing at the University of Melbourne said the review demonstrated racism as an important factor influencing the health and wellbeing of children and youth. "The review showed there are strong and consistent relationships between racial discrimination and a range of detrimental health outcomes such as low self-esteem, reduced resilience, increased behaviour problems and lower ...

Mt. Zion dig reveals possible second temple period priestly mansion

2013-09-17
In excavating sites in a long-inhabited urban area like Jerusalem, archaeologists are accustomed to noting complexity in their finds -- how various occupying civilizations layer over one another during the site's continuous use over millennia. But when an area has also been abandoned for intermittent periods, paradoxically there may be even richer finds uncovered, as some layers have been buried and remainundisturbed by development. Such appears be the case at an archaeological dig on Jerusalem's Mount Zion, conducted by the University of North Carolina at Charlotte, ...

National Heart Centre Singapore discovers patient-specific cure for dangerous heart rhythm disorder

2013-09-17
The National Heart Centre Singapore (NHCS) research team has successfully and completely reversed the effects of the hERG (human ether-a-go-go-related gene) mutation in long QT syndrome 2 (LQTS 2) in patient-specific heart cells, scoring a world's first. Long QT syndrome 2 is a dangerous heart rhythm disorder that can lead to sudden cardiac death, even in young patients. It is caused by a mutation in a specific gene known as hERG, which helps to control the electrical activity in the heart cells and coordinate its beating rhythm. Using the patient's own skin stem cells ...

Digestive disorder reaches record levels in Scots children

2013-09-17
More children than ever before are living with a debilitating digestive disease, research has shown. Scientists have found that coeliac disease affects six times more children living in Scotland now than it did in 1990. A team from the University of Edinburgh and Queen Margaret University analysed the health records of children from South East Scotland aged under 16 years who were newly diagnosed with the condition between 1990 and 2009. The team – based at Royal Hospital for Sick Children in Edinburgh – found that the rate of children being newly diagnosed with Coeliac ...

Virginia Tech researchers help people in remote Africa respond to diarrheal disease

2013-09-17
Using a simple survey tool, a team of researchers has done what complex studies have failed to do -- provide data that identifies starting points for preventing diarrheal disease outbreaks in at least one region of Africa. Diarrheal illness is a leading cause of disease and death in children under 5, and in HIV-plagued Botswana, it is a significant issue for those over 5 as well. "Yet we still know little about the dynamics of this illness and other infectious diseases," said disease ecologist Kathleen Alexander, an associate professor of wildlife in the College of ...

In patients with acute cholecystitis, surgery should be performed immediately

2013-09-17
Should surgery be performed immediately, or is it better to first administer antibiotics and then perform surgery? A study led by Heidelberg University Hospital Department of Surgery has demonstrated that patients suffering from acute cholecystitis should be operated on immediately. There are no advantages to delaying surgery until antibiotic therapy has been administered for several weeks. After undergoing surgery performed within 24 hours of diagnosis, the patients have fewer complications, are back on their feet earlier, and can leave the hospital more quickly. "With ...

First-time measurements in Greenland snowpack show a drop in atmospheric co since 1950s

2013-09-17
A first-ever study of air trapped in the deep snowpack of Greenland shows that atmospheric levels of carbon monoxide (CO) in the 1950s were actually slightly higher than what we have today. This is a surprise because current computer models predict much higher CO concentrations over Greenland today than in 1950. Now it appears the opposite is in fact true. In a paper recently published in the journal Atmospheric Chemistry and Physics, Vasilii Petrenko, an assistant professor of earth and environmental sciences, concluded that CO levels rose slightly from 1950 until the ...

LAST 30 PRESS RELEASES:

Understanding bias and discrimination in AI: Why sociolinguistics holds the key to better Large Language Models and a fairer world 

Safe and energy-efficient quasi-solid battery for electric vehicles and devices

Financial incentives found to help people quit smoking, including during pregnancy

Rewards and financial incentives successfully help people to give up smoking

HKU ecologists reveal key genetic insights for the conservation of iconic cockatoo species

New perspective highlights urgent need for US physician strike regulations

An eye-opening year of extreme weather and climate

Scientists engineer substrates hostile to bacteria but friendly to cells

New tablet shows promise for the control and elimination of intestinal worms

Project to redesign clinical trials for neurologic conditions for underserved populations funded with $2.9M grant to UTHealth Houston

Depression – discovering faster which treatment will work best for which individual

Breakthrough study reveals unexpected cause of winter ozone pollution

nTIDE January 2025 Jobs Report: Encouraging signs in disability employment: A slow but positive trajectory

Generative AI: Uncovering its environmental and social costs

Lower access to air conditioning may increase need for emergency care for wildfire smoke exposure

Dangerous bacterial biofilms have a natural enemy

Food study launched examining bone health of women 60 years and older

CDC awards $1.25M to engineers retooling mine production and safety

Using AI to uncover hospital patients’ long COVID care needs

$1.9M NIH grant will allow researchers to explore how copper kills bacteria

New fossil discovery sheds light on the early evolution of animal nervous systems

A battle of rafts: How molecular dynamics in CAR T cells explain their cancer-killing behavior

Study shows how plant roots access deeper soils in search of water

Study reveals cost differences between Medicare Advantage and traditional Medicare patients in cancer drugs

‘What is that?’ UCalgary scientists explain white patch that appears near northern lights

How many children use Tik Tok against the rules? Most, study finds

Scientists find out why aphasia patients lose the ability to talk about the past and future

Tickling the nerves: Why crime content is popular

Intelligent fight: AI enhances cervical cancer detection

Breakthrough study reveals the secrets behind cordierite’s anomalous thermal expansion

[Press-News.org] Osteoarthritis and the (not so) painful step toward a cure