Semaglutide or tirzepatide and optic nerve and visual pathway disorders in type 2 diabetes

JAMA Network Open

2025-08-11

(Press-News.org) About The Study: In this study of patients with type 2 diabetes who had no prior eye disorders, patients prescribed semaglutide or tirzepatide had an increased risk of nonarteritic anterior ischemic optic neuropathy and other optic nerve disorders, although the overall risk was low. These findings highlight the need for close monitoring of these conditions.

Corresponding Author: To contact the corresponding author, Rong Xu, PhD, email rxx@case.edu.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2025.26327)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

# # #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.26327?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=081125

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

END

ELSE PRESS RELEASES FROM THIS DATE:

Trends and disparities in technology use and glycemic control in type 1 diabetes

2025-08-11

About The Study: In this cross-sectional study, there was a rapid increase in the use of diabetes technology and notable improvements in glycemic control among youths and adults with type 1 diabetes during the past 15 years. Nonetheless, the prevalence of glycemic control remained low, and racial, ethnic, and socioeconomic differences grew over time. Corresponding Author: To contact the corresponding author, Jung-Im Shin, MD, PhD, email jshin19@jh.edu. To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/ (doi:10.1001/jamanetworkopen.2025.26353) Editor’s Note: Please ...

Why these hairy caterpillars swarm every decade – then vanish without a trace

2025-08-11

A 50-year love affair with hairy caterpillars reveals their squirmy secrets Western tent caterpillars might not be on your mind every year, but during their peak outbreaks, they’re impossible to ignore—hairy larvae wriggling across roads and swarms of caterpillars climbing houses to form yellow silken cocoons. They’re certainly on the mind of Dr. Judith Myers, professor emerita in the faculties of science and land and food systems, who has spent five decades studying this native moth species and their boom-and-bust population cycles. In this Q&A, she ...

Kennesaw State physics professor receives three-year grant to create simulations for particle colliders

2025-08-11

Kennesaw State University researcher Andreas Papaefstathiou has received a three-year, $799,651 grant from the U.S. Department of Energy (DOE) to investigate the nature of nuclear matter through collisions of particles at high energies. The findings from Papaefstathiou’s research will help elevate the study of particle physics in the context of nuclear collisions at Kennesaw State, as well as help improve the understanding and interpretation of data coming out of the proposed Electron Ion Collider at the Brookhaven National Laboratory ...

The last mile in Lung Cancer: The web tool turning guidelines into lives saved

2025-08-11

A web-based planning resource developed under the auspices of the American Cancer Society’s National Lung Cancer Roundtable is the rare intervention that marries high-level guidance with local operational reality. The tool is explicitly designed to help state coalitions, health systems, and public-health agencies translate consensus recommendations on lung-cancer prevention, screening, and treatment into stepwise, context-aware implementation plans.

After the storm: to rebuild or relocate?

2025-08-11

Study reveals how residents and government officials in a flood-prone community feel about adapting to climate change -- and how political views may play a role As climate hazards escalate, communities facing repetitive disasters in high-risk areas must weigh the economic and social trade-offs of rebuilding versus relocating. A Risk Analysis study has found that residents and government officials may have different ideas about how public funds should be spent to adapt to extreme weather events brought on by climate change. WHAT THEY DID: To ...

Study urges reform in mental health screening for incarcerated youth

2025-08-11

Approximately 70% of incarcerated youth in the United States have a mental disorder. The challenges in this population are profound – about 30% report suicidal thoughts, 12% have attempted suicide and 25% experience solitary confinement, a condition strongly associated with increased suicide risk. Depression is also widespread, affecting 10% to 25% of youth with moderate to severe symptoms. Comprehensive mental health screenings play a vital role in identifying who requires immediate care, as well as those at risk for developing more serious issues. Without timely identification and intervention, ...

AI could help emergency rooms predict admissions, driving more timely, effective care

2025-08-11

New York, NY [August 11, 2025]— Artificial intelligence (AI) can help emergency department (ED) teams better anticipate which patients will need hospital admission, hours earlier than is currently possible, according to a multi-hospital study by the Mount Sinai Health System. By giving clinicians advance notice, this approach may enhance patient care and the patient experience, reduce overcrowding and “boarding” (when a patient is admitted but remains in the ED because no bed is available), ...

Is writing with AI at work undermining your credibility?

2025-08-11

With over 75% of professionals using AI in their daily work, writing and editing messages with tools like ChatGPT, Gemini, Copilot or Claude has become a commonplace practice. While generative AI tools are seen to make writing easier, are they effective for communicating between managers and employees? A new study of 1,100 professionals reveals a critical paradox in workplace communications: AI tools can make managers’ emails more professional, but regular use can undermine trust between them ...

Parasitic worms evolved to suppress neurons in skin

2025-08-11

New research, published in The Journal of Immunology, discovered that a parasitic worm suppresses neurons in the skin to evade detection. The researchers suggest that the worm likely evolved this mechanism to enhance its own survival, and that the discovery of the molecules responsible for the suppression could aid in the development of new painkillers. Schistosomiasis is a parasitic infection caused by helminths, a type of worm. Infection occurs during contact with infested water through activities like ...

Stalking, obtaining restraining order linked with increased cardiovascular disease risk in women

2025-08-11

Embargoed for release: Monday, August 11, 5:00 AM ET Key points: In a 20-year study, women with experience being stalked had a 41% higher risk of cardiovascular disease (CVD) than women without this experience. Women with experience obtaining a restraining order—typically indicative of severe violence—had a 70% higher risk of CVD than women without that experience. Prior studies have not looked at the relationship between women’s experiences with stalking and CVD outcomes, and few have investigated the link between physical health outcomes and psychological violence commonly faced by women. According to ...

LAST 30 PRESS RELEASES:

Novel endocrine therapy giredestrant improves disease-free survival over standard of care for patients with early-stage breast cancer in phase III lidERA trial

Ancient manatee relative reveals that sea cows have engineered the Arabian Gulf’s seagrass ecosystems for over 20 million years

A study by the University of Seville links the vanishing of the specific heats at absolute zero with the principle of entropy increase

[Press-News.org] Semaglutide or tirzepatide and optic nerve and visual pathway disorders in type 2 diabetes
JAMA Network Open