How does stroke influence speech comprehension?
People with a stroke-related language disorder have key differences in brain activity compared to healthy controls that may explain their impaired verbal speech processing
2025-12-29
(Press-News.org) Following stroke, some people experience a language disorder that hinders their ability to process speech sounds. How do their brains change from stroke? Researchers led by Laura Gwilliams, faculty scholar at the Wu Tsai Neuroscience Institute and Stanford Data Science and assistant professor at the Stanford School of Humanities and Sciences, and Maaike Vandermosten, associate professor at the Department of Neurosciences at KU Leuven, compared the brains of 39 patients following stroke and 24 healthy age-matched controls to unveil language processing brain mechanisms.
As reported in their JNeurosci paper, the researchers recorded brain activity while volunteers listened to a story. People with verbal speech processing issues from stroke were not slower to process speech sounds but had much weaker processing than healthy participants. According to the researchers, this suggests that people with this language disorder can hear sounds of all kinds as well as healthy people but have issues integrating speech sounds to understand language.
Additionally, when there was uncertainty about what words were being said, healthy people processed speech sound features longer compared to those who had experienced a stroke. This could mean that, following stroke, people do not process speech sounds long enough to successfully comprehend words that are difficult to detect.
This work points to brain activity patterns that may be crucial for understanding verbal language, according to the authors. First author Jill Kries expresses excitement about continuing to explore how this simple approach—listening to a story—can be used to improve diagnostics for conditions characterized by language processing issues, which currently involve hours of behavioral tasks.
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About JNeurosci
JNeurosci was launched in 1981 as a means to communicate the findings of the highest quality neuroscience research to the growing field. Today, the journal remains committed to publishing cutting-edge neuroscience that will have an immediate and lasting scientific impact, while responding to authors' changing publishing needs, representing breadth of the field and diversity in authorship.
About The Society for Neuroscience
The Society for Neuroscience is the world's largest organization of scientists and physicians devoted to understanding the brain and nervous system. The nonprofit organization, founded in 1969, now has nearly 35,000 members in more than 95 countries.
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[Press-News.org] How does stroke influence speech comprehension?
People with a stroke-related language disorder have key differences in brain activity compared to healthy controls that may explain their impaired verbal speech processing
