PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Hospitals ranked on complications after hip and knee replacement surgeries

2014-05-12
(Press-News.org) With an aging population comes an increase in hip and knee joint replacement surgeries, totaling almost one million procedures per year in the United States. To provide better information on the outcomes of these surgeries, help inform patient choice, and improve the quality of the nation's hospitals, a team of Yale School of Medicine researchers have developed a measure for hospitals based on the complications following their patients' hip and knee replacements.

The team published an article in the May issue of the Journal of Bone and Joint Surgery showing there are important differences in outcomes across hospitals for these common surgeries. The authors, who are part of the Yale Center for Outcomes Research and Evaluation (CORE), teamed up with leading orthopedic surgeons — including lead author Kevin Bozic of the University of California, San Francisco — and quality experts from the Centers for Medicare & Medicaid Services (CMS) to develop the measure.

The most common complications after hip and knee replacement surgeries are pneumonia, pulmonary embolism, and joint or wound infection, the authors say.

"We found a four-fold difference in risk-adjusted complication rates across hospitals, suggesting some hospitals have substantial room for improvement when it comes to these surgeries," said senior author Elizabeth Drye, M.D., research scientist at Yale School of Medicine and a director of CORE.

"We also looked for, but did not find, evidence of disparities in outcomes," Drye added. "It was reassuring to find that hospitals caring for higher proportions of Medicaid-eligible or black patients did not have higher complication rates."

The hospital measure scores are currently publicly reported for all U.S. hospitals; results are posted at http://www.medicare.gov/hospitalcompare/search.html

Drye and her colleagues also developed a measure of the nation's hospitals based on readmissions at 30 days, which is also reported on the Hospital Compare site. CORE co-author Lisa Suter, working with CMS, is currently leading an effort to develop an outcome measure of patients' functional status following these surgeries.

"Hip and knee replacements are high-volume, costly, and beneficial procedures, and we hope our work will improve how well patients recover after having these surgeries," said Drye.

INFORMATION:

Other CORE authors on the study were Laura Gosso, Zhenqiu Lin, Craig Parzynski, Harlan Krumholz, and Susannah Bernheim.

The work was funded by the Centers for Medicare and Medicaid Services.

Citation: Journal of Bone and Joint Surgery http://www.ncbi.nlm.nih.gov/pubmed/24740660


ELSE PRESS RELEASES FROM THIS DATE:

Dartmouth scientists identify genetic blueprint for cancerous tumors of the appendix

2014-05-12
Using next generation DNA sequencing, Dartmouth scientists have identified potentially actionable mutations in cancers of the appendix. Their study, "Molecular Profiling of Appendiceal Epithelial Tumors Using Massively Parallel Sequencing to Identify Somatic Mutations," was published in the journal Clinical Chemistry today. When specific mutations for a cancer type are identified, patients can be treated with chemotherapy or other targeted agents that work on those mutations. Little is known about the molecular biology of two types of appendix tumors, low-grade appendiceal ...

Ames Lab creates multifunctional nanoparticles for cheaper, cleaner biofuel

Ames Lab creates multifunctional nanoparticles for cheaper, cleaner biofuel
2014-05-12
The U.S. Department of Energy's Ames Laboratory has created a faster, cleaner biofuel refining technology that not only combines processes, it uses widely available materials to reduce costs. Ames Laboratory scientists have developed a nanoparticle that is able to perform two processing functions at once for the production of green diesel, an alternative fuel created from the hydrogenation of oils from renewable feedstocks like algae. The method is a departure from the established process of producing biodiesel, which is accomplished by reacting fats and oils with alcohols. "Conventionally, ...

Mount Sinai researchers identify changes that may occur in neural circuits due to addiction

2014-05-12
A research team from the Friedman Brain Institute of the Icahn School of Medicine at Mount Sinai has published evidence that shows that subtle changes of inhibitory signaling in the reward pathway can change how animals respond to drugs such as cocaine. This is the first study to demonstrate the critical links between the levels of the trafficking protein, the potassium channels' effect on neuronal activity and a mouse's response to cocaine. Results from the study are published in the peer-reviewed journal Neuron on May 7, 2014. The authors investigated the role of ...

Corn dwarfed by temperature dip suitable for growing in mines, caves

Corn dwarfed by temperature dip suitable for growing in mines, caves
2014-05-12
WEST LAFAYETTE, Ind. - Lowering temperatures for two hours each day reduces the height of corn without affecting its seed yield, a Purdue study shows, a technique that could be used to grow crops in controlled-environment facilities in caves and former mines. Raising the crops in isolated and enclosed environments would help prevent genetically modified pollen and seed from escaping into the ecosystem and crossing with wild plants. Cary Mitchell, professor of horticulture, said the technique could be particularly useful for growing transgenic crops to produce high-value ...

INFORMS study: Online buzz forecasts new product performance months before product release

2014-05-12
Companies can significantly improve the forecasting accuracy of forthcoming products' performance by mining online consumer buzz prior to product release, according to a study being published by Marketing Science, a journal of the Institute for Operations Research and the Management Sciences (INFORMS). Social media attention to a firm's forthcoming products also influences its stock price, the study shows. Pre-Release Buzz Evolution Patterns and New Product Performance is by Guiyang Xiong and Sundar Bharadwaj, professors at Terry College of Business at the University ...

Potential cure for captive amphibians with chytrid fungus

2014-05-12
Researchers at Vanderbilt University have identified an alternative to a sometimes toxic therapy that protects frogs in zoos from a deadly fungal infection that has been destroying the amphibian populations worldwide. Their research is published ahead of print in Applied and Environmental Microbiology. The fungal disease, chytridiomycosis, has been decimating frogs all over the world. At present, nothing can help amphibians in the wild, but zoos currently rely on the often-toxic itraconazole to eradicate the disease from infected amphibians they wish to acquire. To ...

UBC scientists find new way to mobilize immune system against viruses

2014-05-12
University of British Columbia scientists have uncovered an intricate chain reaction in the body's immune system and have used the knowledge to develop a new treatment against harmful viruses. Viral pandemics, such as the coronavirus that caused the deadly SARS outbreak in 2002, have caused hundreds of deaths in Canada, yet effective anti-viral drugs are rare. A key element to this natural immune response is an antiviral protein in the blood called Interferon alpha. Like soldiers, Interferon alpha is quickly deployed by the body to fight viruses and removed just as ...

Alcohol and drugs: Not just for modern man

2014-05-12
Unlike modern Man, the prehistoric people of Europe did not use mind-altering substances simply for their hedonistic pleasure. The use of alcohol and plant drugs – such as opium poppies and hallucinogenic mushrooms – was highly regulated and went hand-in-hand with the belief system and sacred burial rituals of many preindustrial societies. Elisa Guerra-Doce of the Universidad de Valladolid in Spain contends that their use was an integral part of prehistoric beliefs, and that these substances were believed to aid in communication with the spiritual world. Guerra-Doce's research ...

All in the rotation

All in the rotation
2014-05-12
Viruses are the enigma of the biological world – despite having their own DNA and being able to adapt to their environment and evolve, they are not considered to be alive like cells. In order to reproduce and multiply – a requirement of "life" - a virus must invade a living cell, eject its DNA into that of the cell, and commandeer the cell's biological machinery. While a virus, essentially, may be nothing more than a dollop of DNA packed into a protective coating of protein called a capsid, the packaging of that DNA is critical. The molecular motors that drive this DNA ...

Video stories, other bonding exercises could help foster families connect

2014-05-12
Teenagers and their foster families often say they don't feel connected and have trouble communicating, but few resources exist that nurture their bonding. In a research paper being published in the June issue of Children and Youth Services Review, researchers affiliated with the University of Washington's School of Social Work describe how they tailored a parenting program known to improve communication in non-foster families for use in foster families. "Every family has its own unique dynamics, such as different rules or expectations. When teens are placed into a foster ...

LAST 30 PRESS RELEASES:

Personalised “cocktails” of antibiotics, probiotics and prebiotics hold great promise in treating a common form of irritable bowel syndrome, pilot study finds

Experts developing immune-enhancing therapies to target tuberculosis

Making transfusion-transmitted malaria in Europe a thing of the past

Experts developing way to harness Nobel Prize winning CRISPR technology to deal with antimicrobial resistance (AMR)

CRISPR is promising to tackle antimicrobial resistance, but remember bacteria can fight back

Ancient Maya blessed their ballcourts

Curran named Fellow of SAE, ASME

Computer scientists unveil novel attacks on cybersecurity

Florida International University graduate student selected for inaugural IDEA2 public policy fellowship

Gene linked to epilepsy, autism decoded in new study

OHSU study finds big jump in addiction treatment at community health clinics

Location, location, location

Getting dynamic information from static snapshots

Food insecurity is significant among inhabitants of the region affected by the Belo Monte dam in Brazil

The Society of Thoracic Surgeons launches new valve surgery risk calculators

Component of keto diet plus immunotherapy may reduce prostate cancer

New circuit boards can be repeatedly recycled

Blood test finds knee osteoarthritis up to eight years before it appears on x-rays

April research news from the Ecological Society of America

Antimicrobial resistance crisis: “Antibiotics are not magic bullets”

Florida dolphin found with highly pathogenic avian flu: Report

Barcodes expand range of high-resolution sensor

DOE Under Secretary for Science and Innovation visits Jefferson Lab

Research expo highlights student and faculty creativity

Imaging technique shows new details of peptide structures

MD Anderson and RUSH unveil RUSH MD Anderson Cancer Center

Tomography-based digital twins of Nd-Fe-b magnets

People with rare longevity mutation may also be protected from cardiovascular disease

Mobile device location data is already used by private companies, so why not for studying human-wildlife interactions, scientists ask

Test reveals mice think like babies

[Press-News.org] Hospitals ranked on complications after hip and knee replacement surgeries