PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Weekend hospital stays worse for kidney patients

'Weekend effect' linked to delayed dialysis, higher risk of death

2010-11-19
(Press-News.org) Patients with end-stage renal disease (ESRD) who are admitted to the hospital during the weekend are at increased risk of death, according to a study presented at the American Society of Nephrology's 43rd Annual Meeting and Scientific Exposition.

"Our study highlights poor outcomes for patients with ESRD admitted over the weekend," comments Ankit Sakhuja, MD, a third year resident in internal medicine at The Medical College of Wisconsin, Milwaukee. "Further research is needed to identify the reasons for this 'weekend effect' and to institute appropriate interventions."

Using a national hospital database, researchers compared mortality rates and other hospital outcomes for ESRD patients hospitalized on weekends versus weekdays. There were more than 800,000 ESRD admissions during 2007, with nearly one fifth admitted over the weekend.

The mortality rate for ESRD patients admitted on weekends was significantly higher than those admitted on weekdays. With adjustment for other factors—including other medical conditions and hospital characteristics—patients admitted on weekends were 17% more likely to die in the hospital compared to patients admitted during the week.

Patients admitted on weekends also experienced delays to the start of dialysis treatment: nearly one-third of a day longer than for patients admitted on weekdays.

Reduced hospital staffing and limited resources on weekends may affect the quality of care. "Weekend effects have been shown in many diseases, including acute myocardial infarction and acute renal failure," according to Dr. Sakhuja.

The results show a similar weekend effect for ESRD patients, including delays to the start of dialysis treatment. "The restricted dialysis services on weekends may result in delayed care of the fluid and electrolyte imbalances, which can result in higher mortality," says Dr. Sakhuja. "Our study stresses the need to redesign hospital staffing models to assure improved staff and dialysis availability for patients dependent on dialysis over the weekends."

The authors note that their study was based on an administrative database prone to coding errors. Because of the nature of the data, it was not possible to ascertain the reasons for poorer outcomes of dialysis-dependent patients admitted over the weekends.

INFORMATION: Study co-authors include Nilay Kumar, MD, Rahul Nanchal, MD, Aaron Dall, MD, and Gagan Kumar, MD, all with The Medical College of Wisconsin.

Disclosures: The authors reported no financial disclosures.

The study abstract, "Weekend Admissions Predict Higher Mortality in Patients with End Stage Renal Disease," [TH-FC045] will be presented as an oral presentation on Thursday, November 18 at 5:18 PM in Room 203 of the Colorado Convention Center in Denver, CO.

ASN Renal Week 2010, the largest nephrology meeting of its kind, will provide a forum for 13,000 professionals to discuss the latest findings in renal research and engage in educational sessions related to advances in the care of patients with kidney and related disorders. Renal Week 2010 will take place November 16 – November 21 at the Colorado Convention Center in Denver, CO.

The content of this article does not reflect the views or opinions of The American Society of Nephrology (ASN). Responsibility for the information and views expressed therein lies entirely with the author(s). ASN does not offer medical advice. All content in ASN publications is for informational purposes only, and is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects. This content should not be used during a medical emergency or for the diagnosis or treatment of any medical condition. Please consult your doctor or other qualified health care provider if you have any questions about a medical condition, or before taking any drug, changing your diet or commencing or discontinuing any course of treatment. Do not ignore or delay obtaining professional medical advice because of information accessed through ASN. Call 911 or your doctor for all medical emergencies.

Founded in 1966, the American Society of Nephrology (ASN) is the world's largest professional society devoted to the study of kidney disease. Comprised of 11,000 physicians and scientists, ASN continues to promote expert patient care, to advance medical research, and to educate the renal community. ASN also informs policymakers about issues of importance to kidney doctors and their patients. ASN funds research, and through its world-renowned meetings and first-class publications, disseminates information and educational tools that empower physicians.


ELSE PRESS RELEASES FROM THIS DATE:

Pomegranate juice: Beyond antioxidants, potential benefits for dialysis patients

2010-11-19
Studies in recent years have claimed multiple health benefits of pomegranate juice, including that it is a good source of antioxidants and lowers both cholesterol and blood pressure, especially in diabetic and hypertensive patients. A preliminary study now suggests that it can ward off a number of complications in kidney disease patients on dialysis, including the high morbidity rate due to infections and cardiovascular events, according to a paper being presented at the American Society of Nephrology's 43rd Annual Meeting and Scientific Exposition in Denver, CO. Batya ...

For macaques, male bonding is a political move

2010-11-19
"We were able to show that the benefit of social bonding accrues through 'the manipulation of ones' own and others' social relationships,' which is one definition of politics," said Oliver Schülke of Georg August University Göttingen in Germany. "The bond does not directly affect access to desirable resources but helps males to climb up the social ladder and to stay up there at the cost of other males that lose their status." Earlier evidence had shown that female animals live longer and have more offspring when they form strong bonds with other females. The benefit of ...

Rare mutations linked with catastrophic aortic aneurysms

2010-11-19
TAAD causes thousands of deaths in the United States each year. Although timely surgical repair of aneurysms can prevent death, thoracic aneurysms are often asymptomatic until dissection (tearing of the vessel wall), and there are few recognized risk factors that can be used for screening. "Prospective identification of patients at risk for TAAD using a genetic strategy will be critical to prevent sudden deaths from this treatable disease," explains senior study author Dr. John W. Belmont from Baylor College of Medicine. To begin to unravel the genetic origins of TAAD, ...

FDA review on transgenic salmon too narrow

2010-11-19
DURHAM, N.C. -- The review process being used by the Food and Drug Administration to assess the safety of a faster-growing transgenic salmon fails to weigh the full effects of the fish's widespread production, according to analysis by a Duke University-led team in this week's Science. The salmon, whose genome contains inserted genes from two other fish species, could become the first genetically modified animal approved for human consumption in the United States. The FDA held two days of hearings in September to assess the fish's human and environmental health risks. ...

It takes a village: Mechanism alerts neighbors to amplify immune response

2010-11-19
The pathogen Shigella flexneri invades the cells that line the gut and causes Shigellosis, a disorder characterized by diarrhea and sometimes even death in humans. S. flexneri subverts the normal immune response of the host by interfering with the ability of the infected cell to secrete chemicals called chemokines that stimulate inflammation. Inflammation is a complex response to pathogens that attracts white blood cells to destroy the bacteria. Despite the documented ability of S. flexneri to suppress inflammation in infected cells, intestinal cells do secrete large amounts ...

Researchers uncover surprise link between weird quantum phenomena

Researchers uncover surprise link between weird quantum phenomena
2010-11-19
Researchers have uncovered a fundamental link between the two defining properties of quantum physics. Stephanie Wehner of Singapore's Centre for Quantum Technologies and the National University of Singapore and Jonathan Oppenheim of the United Kingdom's University of Cambridge published their work today in the latest edition of the journal Science. The result is being heralded as a dramatic breakthrough in our basic understanding of quantum mechanics and provides new clues to researchers seeking to understand the foundations of quantum theory. The result addresses the ...

Panama Canal, Panama City at risk of large earthquake, says new research

2010-11-19
Panama Canal, PanNew data suggest that the Limon and Pedro Miguel faults in Central Panama have ruptured both independently and in unison over the past 1400 years, indicating a significant seismic risk for Panama City and the Panama Canal, according to research published today by the Bulletin of the Seismological Society of America (BSSA). The Panama Canal is undergoing expansion to allow for greater traffic of larger ships, scheduled for completion by 2014. As part of a seismic hazard characterization for the Panama Canal Authority (ACP) expansion project, Rockwell, ...

Planet from another galaxy discovered

Planet from another galaxy discovered
2010-11-19
Over the last 15 years, astronomers have detected nearly 500 planets orbiting stars in our cosmic neighbourhood, but none outside our Milky Way has been confirmed [1]. Now, however, a planet with a minimum mass 1.25 times that of Jupiter [2] has been discovered orbiting a star of extragalactic origin, even though the star now finds itself within our own galaxy. It is part of the so-called Helmi stream — a group of stars that originally belonged to a dwarf galaxy that was devoured by our galaxy, the Milky Way, in an act of galactic cannibalism about six to nine billion years ...

Paleovirology expanded: Non-retroviral virus fragments found in animal genomes

2010-11-19
Understanding the evolution of life-threatening viruses like influenza, Ebola and dengue fever, could help us to minimize their impact. New research points the way to a fossil record of viruses that have insinuated themselves into the genomes of insects and other animals, providing clues about their evolutionary history. The findings, published online on November 18 in the open-access journal PLoS Genetics, could enable scientists to elucidate general principles in virus evolution from their genetic "fossils", which in turn could inform approaches for controlling disease. Robert ...

Scripps Research scientists report molecular structure of dopamine receptor

2010-11-19
LA JOLLA, CA – November 16, 2010 – A team led by scientists at The Scripps Research Institute has solved the structure of one of the receptors that responds to the neurotransmitter dopamine. Although dopamine transmission is essential to normal brain functioning, the biological assembly of the molecules involved in this crucial neuronal interplay had not been known—until now. The work was reported in the November 19, 2010, issue of the journal Science. In the new study, whose authors included collaborators from Weill Cornell Medical College, Receptos, the National Institute ...

LAST 30 PRESS RELEASES:

Insulin resistance is linked to over 30 diseases – and to early death in women, study of people in the UK finds

Innovative semaglutide hydrogel could reduce diabetes shots to once a month

Weight loss could reduce the risk of severe infections in people with diabetes, UK research suggests

Long-term exposure to air pollution and a lack of green space increases the risk of hospitalization for respiratory conditions

Better cardiovascular health in early pregnancy may offset high genetic risk

Artificial intelligence method transforms gene mutation prediction in lung cancer: DeepGEM data releases at IASLC 2024 World Conference on Lung Cancer

Antibody–drug conjugate I-DXd shows clinically meaningful response in patients with extensive-stage small cell lung cancer

IASLC Global Survey on biomarker testing reveals progress and persistent barriers in lung cancer biomarker testing

Research shows pathway to developing predictive biomarkers for immune checkpoint inhibitors

Just how dangerous is Great Salt Lake dust? New research looks for clues

Maroulas appointed Associate Vice Chancellor, Director of AI Tennessee

New chickadee research finds cognitive skills impact lifespan

Cognitive behavioral therapy enhances brain circuits to relieve depression

Terasaki Institute awarded $2.3 Million grant from NIH for organ transplantation research using organs-on-a-chip technology

Atoms on the edge

Postdoc takes multipronged approach to muon detection

Mathematical proof: Five satellites needed for precise navigation

Scalable, multi-functional device lays groundwork for advanced quantum applications

Falling for financial scams? It may signal early Alzheimer’s disease

Integrating MRI and OCT for new insights into brain microstructure

Designing a normative neuroimaging library to support diagnosis of traumatic brain injury

Department of Energy announces $68 million in funding for artificial intelligence for scientific research

DOE, ORNL announce opportunity to define future of high-performance computing

Molecular simulations, supercomputing lead to energy-saving biomaterials breakthrough

Low-impact yoga and exercise found to help older women manage urinary incontinence

Genetic studies reveal new insights into cognitive impairment in schizophrenia

Researcher develops technology to provide cleaner energy and cleaner water

Expect the unexpected: nanoscale silver unveils intrinsic self-healing abilities

nTIDE September 2024 Jobs Report: Gains in employment for people with disabilities appear to level off after reducing gaps with non-disabled workers

Wiley enhances NMR Spectral Library Collection with extensive new databases

[Press-News.org] Weekend hospital stays worse for kidney patients
'Weekend effect' linked to delayed dialysis, higher risk of death