(Press-News.org) After complete transection of a nerve, good neuroanastomosis is needed to prevent the formation of fibrous connective tissues that form obstacles to nerve regeneration, and to facilitate repair of the injured nerve and reinnervation of its original targets. Peripheral nerve defects of more than 10 mm are commonly treated in clinics, and in these injuries a conduit is needed to bridge the gap, prevent the formation of obstacles to nerve regeneration, and guide axonal regrowth. Autogenous vein grafts have been used extensively for the repair of nerve defects in rats. Motor reinnervation of skeletal muscle after repair of nerve defects using vein grafts has been confirmed both structurally and neurophysiologically. However, no previous studies have reported on sensory reinnervation of skeletal muscle after repair of nerve defects using vein grafts. Dr. Youwang Pang and colleagues from the 180 Hospital of Chinese PLA used immunohistochemical and electrophysiological examinations to evaluate reinnervation of muscle spindles in rat gastrocnemius muscles after excision of 10-mm segments of the tibial nerves and bridging with autologous vein grafts. These researchers found that there were no significant differences in the number, size, or electrophysiological function of reinnervated muscle spindles between the two experimental groups. These findings, published in the Neural Regeneration Research, suggest that repair of short nerve defects with autologous vein grafts provides comparable results to immediate end-to-end anastomosis in terms of sensory reinnervation of muscle spindles.
INFORMATION:
Article
" Sensory reinnervation of muscle spindles after repair of tibial nerve defects using autogenous vein grafts," by Youwang Pang, Qingnan Hong, Jinan Zheng (Department of Orthopedics, the 180 Hospital of Chinese PLA, Quanzhou, Fujian Province, China)
Pang YW, Hong QN, Zheng JN. Sensory reinnervation of muscle spindles after repair of tibial nerve defects using autogenous vein grafts. Neural Regen Res. 2014;9(6):610-615.
Contact
Meng Zhao
eic@nrren.org
86-138-049-98773
Neural Regeneration Research
http://www.nrronline.org/
Sensory reinnervation of muscle spindles after TN defect repaired by autologous vein graft
2014-09-03
ELSE PRESS RELEASES FROM THIS DATE:
Puerarin accelerates neural regeneration after sciatic nerve injury
2014-09-03
Puerarin is a natural isoflavone isolated from plants of the genus Pueraria and functions as a protector against cerebral ischemia. Can puerarin be involved in the repair of peripheral nerve injuries? Minfei Wu and co-workers from the Second Hospital of Jilin University in China verified that puerarin exerts an ongoing role to activate growth-associated protein 43 in the corresponding segment of the spinal cord after sciatic nerve injury, thus contributing to neural regeneration after sciatic nerve injuries. Their relevant study has been reported in the Neural Regeneration ...
Researchers demonstrate direct brain-to-brain communication in human subjects
2014-09-03
BOSTON –In a first-of-its-kind study, an international team of neuroscientists and robotics engineers have demonstrated the viability of direct brain-to-brain communication in humans. Recently published in PLOS ONE the highly novel findings describe the successful transmission of information via the internet between the intact scalps of two human subjects – located 5,000 miles apart.
"We wanted to find out if one could communicate directly between two people by reading out the brain activity from one person and injecting brain activity into the second person, and do ...
Wind energy cuts the electricity bill
2014-09-03
This news release is available in Spanish.
The UPV/EHU study analyses the electricity market in Spain during the 2008-2012 period -a time of maximum renewable penetration in Spain when energy production within the Special Scheme saw a 57% increase- and quantifies its cost.
To do this, they firstly measured the market savings produced by participating in renewable sources, and secondly, they calculated the amount paid in the form of incentives to green energy. The difference between the two figures represents the net cost of renewable energy. In contrast to other ...
Mouse studies advance treatment for common eye diseases
2014-09-03
Working with mice, a multicenter team of researchers has found a new way to reduce the abnormal blood vessel growth and leakage in the eye that accompany some eye diseases. The finding could lead to the development of new drugs for wet macular degeneration and diabetic macular edema.
The team reports their findings in the Sept. 2 issue of The Journal of Clinical Investigation.
The current standard of clinical care for wet macular degeneration and diabetic macular edema is repeated injections into the eye of antibodies against a protein called VEGF. Each injection costs ...
UNH survey: Milk prices top concern of Northeastern organic dairy farmers
2014-09-03
Northeastern organic dairy farms say their top concern is receiving steady, fair prices for their milk from milk processors, according to a new survey that is the first to assess the research and educational needs of organic dairy farmers in the region. The research is funded by the NH Agricultural Experiment Station at the University of New Hampshire College of Life Sciences and Agriculture.
While this finding won't come as news to dairy farmers, it may surprise organic milk consumers who pay considerably more for organic milk than conventional milk at the grocery. ...
Handheld scanner could make brain tumor removal more complete, reducing recurrence
2014-09-03
Cancerous brain tumors are notorious for growing back despite surgical attempts to remove them — and for leading to a dire prognosis for patients. But scientists are developing a new way to try to root out malignant cells during surgery so fewer or none get left behind to form new tumors. The method, reported in the journal ACS Nano, could someday vastly improve the outlook for patients.
Moritz F. Kircher and colleagues at Memorial Sloan Kettering Cancer Center point out that malignant brain tumors, particularly the kind known as glioblastoma multiforme (GBM), are among ...
Nature or nurture? It's all about the message
2014-09-03
EAST LANSING, Mich. --- Were Albert Einstein and Leonardo da Vinci born brilliant or did they acquire their intelligence through effort?
No one knows for sure, but telling people the latter – that hard work trumps genes – causes instant changes in the brain and may make them more willing to strive for success, indicates a new study from Michigan State University.
The findings suggest the human brain is more receptive to the message that intelligence comes from the environment, regardless of whether it's true. And this simple message, said lead investigator Hans Schroder, ...
Could a protein be linked to heart attacks?
2014-09-03
OTTAWA, September 3, 2014 – A team of researchers at the University of Ottawa Heart Institute, led by Dr. Alexandre Stewart, have uncovered an intriguing link between heart attacks and a protein that is of great interest to drug companies for its impact on cholesterol.
The team found that levels of the protein PCSK9 were elevated in the blood of patients having an acute heart attack, but not in those who never had a heart attack or who had recovered from one previously. The results were replicated in two separate groups of patients, all of whom have coronary artery disease ...
New paper calls for more infection control surveillance, standardization in the emergency department
2014-09-03
Washington, DC, September 3, 2014 – When researchers searched the literature to determine adherence rates for various infection prevention protocols in the emergency department (ED), they discovered both a dearth of studies reporting ED practices and a lack of standardization that rendered some studies incomparable, according to a literature review published in the September issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC).
A team of researchers from Columbia ...
Lead and cadmium found in some chocolate bought in Brazil
2014-09-03
Scientists have found that commercial samples of chocolate purchased in Brazil contain varying levels of lead and cadmium, which can cause health problems, and that those levels are linked to how much cocoa a product contains. They reported their findings, which could have health implications — particularly for children — in ACS' Journal of Agricultural and Food Chemistry.
Solange Cadore and colleagues note that chocolate has many potential health benefits due to the high levels of flavonoids and antioxidants in its star ingredient, cocoa. But they also explain that other ...