(Press-News.org) Dr Stephen Martin and colleagues argue that this strategy is failing patients and wasting healthcare resources. They call for a re-examination of the threshold and urge clinicians to be cautious about treating low risk patients with blood pressure lowering drugs.
Their paper publishes as the Preventing Overdiagnosis conference opens next week (Monday 15 Sept), where experts from around the world will discuss how to tackle the threat to health and the waste of money caused by unnecessary care. The conference is hosted by the Centre for Evidence-Based Medicine at the University of Oxford in partnership with The BMJ's Too Much Medicine campaign.
Up to 40% of adults worldwide have hypertension, over half of which is classified as "mild." Low risk indicates that an individual does not have existing cardiovascular disease, diabetes, or kidney disease.
Over the years, hypertension has been treated with drugs at progressively lower blood pressures. The belief has been that drug treatment of even mildly elevated blood pressure levels in low risk patients may reduce cardiovascular risk.
Over half of people with mild hypertension are treated with medication. Yet treating low risk mildly hypertensive patients with drugs has not been proven to reduce cardiovascular disease or death.
In the US alone, where hypertension is the most common condition for a medical visit, the cost of drug treatment of mild hypertension has been estimated at $32 billion (£19bn; €24bn) per year. This corresponds to more than 1% of annual healthcare costs and more than one third of total US expenditures on public health.
The authors argue that overemphasis on drug treatment "risks adverse effects, such as increased risk of falls, and misses opportunities to modify individual lifestyle choices and tackle lifestyle factors at a public health level."
And they urge clinicians to share the uncertainty surrounding drug treatment of mild hypertension with patients, measure blood pressure at home, improve accuracy of clinic measurements, promote public health investment, and "encourage lifestyle changes to treat hypertension, including weight loss, smoking cessation, decreased alcohol consumption and increased exercise."
An animation to illustrate mild hypertension and its management is available here.
INFORMATION: END
Experts raise concern over unnecessary treatment of mild hypertension in low risk people
Benefits of drug treatment for low risk patients 'still open to question'
2014-09-15
ELSE PRESS RELEASES FROM THIS DATE:
Genetic testing can identify men at 6-fold increased risk of prostate cancer
2014-09-15
Scientists can now explain a third of the inherited risk of prostate cancer, after a major international study identified 23 new genetic variants associated with increased risk of the disease.
The study brings the total number of common genetic variants linked to prostate cancer to 100, and testing for them can identify 1% of men with a risk of the disease almost six times as high as the population average.
Scientists at The Institute of Cancer Research, London, and in Cambridge, UK, and California led a huge search for new genetic variants including almost 90,000 men ...
Rules of thumb for climate change turned upside down
2014-09-15
Based on models and observations, climate scientists have devised a simplified formula to describe one of the consequences of climate change: regions already marked by droughts will continue to dry out in the future climate. Regions that already have a moist climate will experience additional rainfall. In short: dry gets drier; wet gets wetter (DDWW).
However, this formula is less universally valid than previously assumed. This was demonstrated by a team of ETH climate researchers led by Peter Greve, lead author of a study recently published in Nature Geoscience. Traditional ...
Measuring modified protein structures
2014-09-15
Cells regulate protein functions in a wide variety of ways, including by modifying the protein structure. In an instant, a protein can take on another form and perform no or even the "wrong" function: in humans, proteins that fold wrongly can cause serious diseases such as Alzheimer's, Parkinson's or cystic fibrosis. Some of these proteins also have a tendency to "infect" other molecules of the same type and congregate into insoluble so-called amyloid fibrils or plaques. These amyloids can damage cells and tissues and make people ill.
Method breaks the shackles
Until ...
UNC researchers find final pieces to the circadian clock puzzle
2014-09-15
CHAPEL HILL, NC – Researchers at the UNC School of Medicine have discovered how two genes – Period and Cryptochrome – keep the circadian clocks in all human cells in time and in proper rhythm with the 24-hour day, as well as the seasons. The finding, published today in the journal Genes and Development, has implications for the development of drugs for various diseases such as cancers and diabetes, as well as conditions such as metabolic syndrome, insomnia, seasonal affective disorder, obesity, and even jetlag.
"Discovering how these circadian clock genes interact has ...
Cheaper alternative to licensed drug for treating eye disease has similar side-effects
2014-09-15
Health policies which favour using ranibizumab for treating eye disease in older people over safety concerns for a cheaper alternative should take account of a new Cochrane Review published today. The researchers looked at the results of studies which compared the safety of two drugs used for treating age-related macular degeneration, ranibizumab and bevacizumab. Contrary to what was argued by some experts the review has found that the cheaper drug, bevacizumab, does not appear to increase deaths or serious side-effects compared with ranibizumab in people with neovascular ...
Study sheds new light on why batteries go bad
2014-09-15
Menlo Park, Calif. — A comprehensive look at how tiny particles in a lithium ion battery electrode behave shows that rapid-charging the battery and using it to do high-power, rapidly draining work may not be as damaging as researchers had thought – and that the benefits of slow draining and charging may have been overestimated.
The results challenge the prevailing view that "supercharging" batteries is always harder on battery electrodes than charging at slower rates, according to researchers from Stanford University and the Stanford Institute for Materials & Energy Sciences ...
Marijuana users who feel low get high
2014-09-15
PISCATAWAY, NJ – Adolescents and young adults who smoke marijuana frequently may attempt to manage negative moods by using the drug, according to a study in September's Journal of Studies on Alcohol and Drugs.
"Young people who use marijuana frequently experience an increase in negative affect in the 24 hours leading up to a use event, which lends strong support to an affect-regulation model in this population," says the study's lead author Lydia A. Shrier, M.D., M.P.H., of the division of adolescent and young adult medicine at Boston Children's Hospital.
She notes ...
Hypersensitivity to non-painful events may be part of pathology in fibromyalgia
2014-09-15
New research shows that patients with fibromyalgia have hypersensitivity to non-painful events based on images of the patients' brains, which show reduced activation in primary sensory regions and increased activation in sensory integration areas. Findings published in Arthritis & Rheumatology, a journal of the American College of Rheumatology (ACR), suggest that brain abnormalities in response to non-painful sensory stimulation may cause the increased unpleasantness that patients experience in response to daily visual, auditory and tactile stimulation.
Fibromyalgia ...
New knowledge of genes driving bladder cancer points to targeted treatments
2014-09-15
The story of cancer care seems so simple: find the mutated gene that causes cancer and turn it off or fix it. But rarely does a single gene cause cancer. More often, many genes are altered together to drive the disease. So the challenge becomes sorting out which altered genes are the most to blame in which cancers. A collaborative study between researchers at the University of Colorado Cancer Center and the National Cancer Institute (NCI) published today in the journal Clinical Cancer Research takes an important step toward answering this question in bladder cancer.
Specifically, ...
Identifying a better message strategy for dissuading smokers: Add the positive
2014-09-15
WASHINGTON — Which is more likely to convince a smoker to quit? The words, "Warning: cigarettes cause cancer" beneath the image of an open mouth with a cancerous lesion and rotten teeth, or the same image with the words, "Warning: Quitting smoking reduces the risk of cancer"?
The answer depends on how confident you are in your ability to quit, according to a study led by researchers at Georgetown Lombardi Comprehensive Cancer Center and published in the journal Nicotine & Tobacco Research.
The research, which involved 740 participants and three D.C. area institutions, ...
LAST 30 PRESS RELEASES:
Post-LLM era: New horizons for AI with knowledge, collaboration, and co-evolution
“Sloshing” from celestial collisions solves mystery of how galactic clusters stay hot
Children poisoned by the synthetic opioid, fentanyl, has risen in the U.S. – eight years of national data shows
USC researchers observe mice may have a form of first aid
VUMC to develop AI technology for therapeutic antibody discovery
Unlocking the hidden proteome: The role of coding circular RNA in cancer
Advancing lung cancer treatment: Understanding the differences between LUAD and LUSC
Study reveals widening heart disease disparities in the US
The role of ubiquitination in cancer stem cell regulation
New insights into LSD1: a key regulator in disease pathogenesis
Vanderbilt lung transplant establishes new record
Revolutionizing cancer treatment: targeting EZH2 for a new era of precision medicine
Metasurface technology offers a compact way to generate multiphoton entanglement
Effort seeks to increase cancer-gene testing in primary care
Acoustofluidics-based method facilitates intracellular nanoparticle delivery
Sulfur bacteria team up to break down organic substances in the seabed
Stretching spider silk makes it stronger
Earth's orbital rhythms link timing of giant eruptions and climate change
Ammonia build-up kills liver cells but can be prevented using existing drug
New technical guidelines pave the way for widespread adoption of methane-reducing feed additives in dairy and livestock
Eradivir announces Phase 2 human challenge study of EV25 in healthy adults infected with influenza
New study finds that tooth size in Otaria byronia reflects historical shifts in population abundance
nTIDE March 2025 Jobs Report: Employment rate for people with disabilities holds steady at new plateau, despite February dip
Breakthrough cardiac regeneration research offers hope for the treatment of ischemic heart failure
Fluoride in drinking water is associated with impaired childhood cognition
New composite structure boosts polypropylene’s low-temperature toughness
While most Americans strongly support civics education in schools, partisan divide on DEI policies and free speech on college campuses remains
Revolutionizing surface science: Visualization of local dielectric properties of surfaces
LearningEMS: A new framework for electric vehicle energy management
Nearly half of popular tropical plant group related to birds-of-paradise and bananas are threatened with extinction
[Press-News.org] Experts raise concern over unnecessary treatment of mild hypertension in low risk peopleBenefits of drug treatment for low risk patients 'still open to question'