PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Study estimates 14 million smoking-attributable major medical conditions in US

2014-10-13
(Press-News.org) Bottom Line: Adults in the United States suffered from approximately 14 million major medical conditions attributable to smoking.

Author: Brian L. Rostron, Ph.D., M.P.H., of the Center for Tobacco Products, U.S. Food and Drug Administration, Silver Spring, Md., and colleagues.

Background: Smoking is the leading cause of preventable disease in the United States. Cigarette smoking harms nearly every organ and organ system in the body. The authors estimated major medical conditions (morbidity) attributed to smoking in 2009.

How the Study Was Conducted: The authors used data from the U.S. Census Bureau in 2009, National Health Interview Survey data from 2006 through 2012 and data from the National Health and Nutrition Examination Survey.

Results: First, the authors used National Health Interview Survey data to estimate that 6.9 million U.S. adults had a combined 10.9 million self-reported smoking-attributable medical conditions. Then, the authors used chronic obstructive pulmonary disease (COPD) prevalence estimates from the National Health and Nutrition Examination Survey of self-reported and spirometry (a test of lung function) data to estimate that U.S. adults had had a combined 14 million smoking attributable-conditions in 2009. The largest cause of smoking-attributable illness in the United States was still COPD (emphysema) with an estimated 7.5 million cases attributable to smoking, but this number is 70 percent higher than the estimated cases based on self-reported prevalence data.

Discussion: "The disease burden of cigarette smoking in the United States remains immense and updated estimates indicate that COPD may be substantially underreported in health survey data." (JAMA Intern Med. Published online October 13, 2014. doi:10.1001/jamainternmed.2014.5219. Available pre-embargo to the media at http://media.jamanetwork.com.)

Editor's Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Commentary: Even More Illness Caused by Smoking Than Previously Estimated

In a related commentary, Steven A. Schroeder, M.D., of the University of California, San Francisco, writes: "The data from Rostron et al should serve to keep tobacco control and its 2-fold aims of preventing initiation and helping smokers quit as the most important clinical and public health priorities for the foreseeable future."

"Tobacco control has been called one of the most important health triumphs of the past 50 years. Yet, although we have come a long way, there is still much more to be done, with the number of smokers worldwide now just short of 1 billion people. The article by Rostron et al is a stark reminder of that unfinished work," the author concludes. (JAMA Intern Med. Published online October 13, 2014. doi:10.1001/jamainternmed.2014.4297. Available pre-embargo to the media at http://media.jamanetwork.com.)

Editor's Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

INFORMATION: Media Advisory: To contact author Brian L. Rostron, Ph.D., M.P.H., call Jenny Haliski at 301-796-0776 or email jennifer.haliski@fda.hhs.gov. To contact commentary author Steven A. Schroeder, M.D., call Elizabeth Fernandez at 415-514-1592 or email Elizabeth.Fernandez@UCSF.edu. A podcast with the authors will be available when the embargo lifts on the JAMA Internal Medicine website: http://bit.ly/IZGqPC


ELSE PRESS RELEASES FROM THIS DATE:

No association seen between physical activity, depressive symptoms in adolescents

2014-10-13
Bottom Line: A study of teenagers suggests there is no association between physical activity (PA) and the development of depressive symptoms later in adolescence. Author: Umar Toseeb, Ph.D., of the University of Cambridge, United Kingdom, and colleagues. Background: Depression contributes to the global burden of disease. A reduction in the associated costs – both personal and financial – would benefit society. The onset of depression is thought to happen in adolescence or earlier so preventive measures during this period of life could be beneficial. PA ...

Dysregulation in orexinergic system associated with Alzheimer disease

2014-10-13
Bottom Line: In patients with Alzheimer disease (AD), increased cerebrospinal fluid levels of orexin, which helps regulate the sleep-wake cycle, may be associated with sleep deterioration, which appears to be associated with cognitive decline. Authors: Claudio Liguori, M.D., of the University of Rome Tor Vergata, Italy, and colleagues. Background: AD is a neurodegenerative disease marked by progressive memory loss and cognitive decline and often complicated by sleep disturbance. Orexin A is part of the orexinergic system and it helps regulate the sleep-wake cycle ...

Chemical derived from broccoli sprouts shows promise in treating autism

Chemical derived from broccoli sprouts shows promise in treating autism
2014-10-13
Results of a small clinical trial suggest that a chemical derived from broccoli sprouts — and best known for claims that it can help prevent certain cancers — may ease classic behavioral symptoms in those with autism spectrum disorders (ASDs). The study, a joint effort by scientists at MassGeneral Hospital for Children and the Johns Hopkins University School of Medicine, involved 40 teenage boys and young men, ages 13 to 27, with moderate to severe autism. In a report published online in the journal Proceedings of the National Academy of Sciences during ...

Chemical present in broccoli, other vegetables may improve autism symptoms

2014-10-13
A small study led by investigators at MassGeneral Hospital for Children (MGHfC) and Johns Hopkins University School of Medicine has found evidence that daily treatment with sulforaphane – a molecule found in foods such as broccoli, cauliflower and cabbage – may improve some symptoms of autism spectrum disorders. In their report being published online in PNAS Early Edition, the investigators describe how participants receiving a daily dose of sulforaphane showed improvement in both behavioral and communication assessments in as little as four weeks. The authors ...

Greater rates of mitochondrial mutations discovered in children born to older mothers

Greater rates of mitochondrial mutations discovered in children born to older mothers
2014-10-13
The discovery of a "maternal age effect" by a team of Penn State scientists that could be used to predict the accumulation of mitochondrial DNA mutations in maternal egg cells -- and the transmission of these mutations to children -- could provide valuable insights for genetic counseling. These mutations cause more than 200 diseases and contribute to others such as diabetes, cancer, Parkinson's disease, and Alzheimer's disease. The study found greater rates of the mitochondrial DNA variants in children born to older mothers, as well as in the mothers themselves. The research ...

Paving the way for a fructose tolerance test

2014-10-13
BOSTON – Increased consumption of table sugar and high-fructose corn syrup has been linked to rising rates of obesity and type 2 diabetes in the United States and throughout the world. Both sweeteners are commonly found in processed foods and sugar-sweetened beverages, and both are made up of nearly equal amounts of two basic sugars, glucose and fructose. The effects of glucose ingestion in humans are well understood, in part, because they are easily assessed by performing a Glucose Tolerance Test, which measures serum glucose levels after glucose ingestion and ...

Moderate levels of 'free radicals' found beneficial to healing wounds

2014-10-13
Long assumed to be destructive to tissues and cells, "free radicals" generated by the cell's mitochondria—the energy producing structures in the cell—are actually beneficial to healing wounds. That's the conclusion of biologists at UC San Diego who discovered that "reactive oxygen species"—chemically reactive molecules containing oxygen, such as peroxides, commonly referred to as free radicals—are necessary for the proper healing of skin wounds in the laboratory roundworm C. elegans. In a paper published in the October 13 issue of the journal ...

New cancer drug to begin trials in multiple myeloma patients

2014-10-13
Scientists at Imperial College London have developed a new cancer drug which they plan to trial in multiple myeloma patients by the end of next year. In a paper published today in the journal Cancer Cell, the researchers report how the drug, known as DTP3, kills myeloma cells in laboratory tests in human cells and mice, without causing any toxic side effects, which is the main problem with most other cancer drugs. The new drug works by stopping a key process that allows cancer cells to multiply. The team have been awarded Biomedical Catalyst funding from the Medical ...

A new land snail species named for equal marriage rights

A new land snail species named for equal marriage rights
2014-10-13
Scientists from the Department of Life Science, National Taiwan Normal University and the Biodiversity Research Center, Academia Sinica described a new endemic land snail species. The new species Aegista diversifamilia was long confused for the widely distributed A. subchinensis. The study was published in the open access journal ZooKeys. Aegista subchinensis was first described in 1884 and was thought to be widely distributed in Taiwan. In 2003, one of the co-authors Dr. Yen-Chang Lee noticed that there was morphological divergence between the western and eastern populations ...

Versatile antibiotic found with self-immunity gene on plasmid in staph strain

2014-10-13
WASHINGTON, DC – OCTOBER 10, 2014 - A robust, broad spectrum antibiotic, and a gene that confers immunity to that antibiotic are both found in the bacterium Staphylococcus epidermidis Strain 115. The antibiotic, a member of the thiopeptide family of antibiotics, is not in widespread use, partly due to its complex structure, but the investigators, from Brigham Young University, Provo, Utah, now report that the mechanism of synthesis is surprisingly simple. "We hope to come up with innovative processes for large-scale production and derivitization so that new, and possibly ...

LAST 30 PRESS RELEASES:

Global health impacts of plastics systems could double by 2040

Low-cost system turns smartphones into emergency radiation detectors

Menopause linked to loss of grey matter in the brain, poorer mental health and sleep disturbance

New expert guidelines standardize diagnosis and monitoring of canine dementia

Study links salty drinking water to higher blood pressure, especially in coastal areas

Study reveals struggles precede psychosis risk by years, suggesting prevention opportunities

Nearly half of CDC surveillance databases have halted updates, raising concerns about health data gaps

Study compares ways to support opioid deprescribing in primary care

Primary care home visits for older adults declined after payment policy changes and COVID-19 in Ontario, Canada

Linking financial incentives to improved blood sugar levels may support type 2 diabetes management

Care continuity linked to fewer hospital visits for older adults receiving home-based care

Produce prescriptions improve nutrition for medicaid patients with diabetes

CRISP translation guide enables translating research-reporting guidelines across languages

How patients value visit type, speed of care, and continuity in primary care

Systems-level approach in primary care improves alcohol screening, counseling, and pregnancy-intention records

Why family physicians are leaving comprehensive care

WVU research team working to restore sight lost to genetic eye disease

New data show reduced overall PFAS exposures in subarctic ocean

AI sheds light on mysterious dinosaur footprints

Changes to cougar diets and behaviors reduce their competition with wolves in Yellowstone, study finds

Researchers discover a previously unknown bacterial component in kidney stone formation

University of Oklahoma researcher awarded NIH grant to advance tribally defined approaches to genomic research

ARPA-H award will fund creation of portable lymphatic imaging scanner

New study may offer hope to women suffering menopausal hot flashes, night sweats

From experience-based simulations to predictive science

SERIDA develops a remote sensing model to improve the control of fossorial water vole populations in agricultural areas of Northwestern Spain

New guideline expands stroke treatment for adults, offers first pediatric stroke guidance

Gout medication can reduce the risk of heart attack and stroke, finds new study

Astronomers reveal new details about dark matter’s influence on Universe

Cumulative lifespan stress, inflammation, and racial disparities in mortality between black and white adults

[Press-News.org] Study estimates 14 million smoking-attributable major medical conditions in US