PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Few operations for epilepsy despite their safety and efficacy

Few operations for epilepsy despite their safety and efficacy
2014-11-25
(Press-News.org) The study at Sahlgrenska Academy, University of Gothenburg, was based on the Swedish National Epilepsy Surgery Register, which includes all cases since 1990. The researchers reviewed data for the 865 patients who were operated on at Sweden's six epilepsy surgery clinics from 1996 to 2010.

The purpose of surgery is to enable a person with severe epilepsy to be free of seizures or to reduce their frequency to the point that (s)he can enjoy better quality of life.

Downward trend Only 3% (25) of the patients suffered lasting complications. A comparison with a previous study showed that the complication rate had trended downward.

The Gothenburg study is one of many that have demonstrated the safety and efficacy of epilepsy surgery. A long-term follow-up study in 2013 based on the Swedish National Epilepsy Surgery Register found that more than 60% of adults were free of seizures 5-10 years after surgery.

20 year waiting line Despite the encouraging data, only 50-60 procedures are performed in Sweden every year. Studies show that it takes an average of 20 years for a patient with treatment-resistant epilepsy to be referred for presurgical counseling.

"One possible reason that it takes so long is that doctors may erroneously believe that surgery is a high-risk procedure," says Johan Bjellvi, a researcher at Sahlgrenska Academy. "Our study has made an important contribution by demonstrating that the risk of complications is very low."

Another problem is that many patients do not even know that surgery is an option.

Raise awarness The Gothenburg epilepsy surgery team is participating in an EU project to raise awareness and increase the availability of these procedures throughout Europe. One goal is to develop a new classification system for complications of epilepsy surgery.

"If we are going to further minimize the risk of operating, the potential adverse effects must be described in a uniform manner," Dr. Bjellvi says. "The EU project is designing a website for use by both doctors and patients in 17 countries."

INFORMATION:

The article Complications of Epilepsy Surgery in Sweden 1996-2010: a Prospective, Population-based Study was published online by the Journal of Neurosurgery in October.

Link to summary: http://www.ncbi.nlm.nih.gov/pubmed/25361484

Feel free to contact:
Dr. Johan Bjellvi, researcher at Sahlgrenska Academy, University of Gothenburg
Phone +46 31-3429079
Phone +46 709-301420
johan.bjellvi@vgregion.se

EPILEPSY FACTS Epilepsy manifests as seizures, with or without causing convulsions or affecting consciousness. Seizures are due to transient disturbances of the brain's neural electrical impulses. The cause may be temporary or permanent brain damage but cannot always be determined. Approximately 1% of Swedes are predisposed to experience recurring epileptic seizures. Both drugs and surgical methods are available to relieve the symptoms.

The purpose of surgery is to enable the patient to be free of seizures, to minimize their frequency or to reduce their severity by preventing involvement of larger areas of the brain. Many different procedures are available. Anterior temporal lobectomy is the most common. The purpose of certain other procedures is to limit the diffusion pathways of epileptic activity.


[Attachments] See images for this press release:
Few operations for epilepsy despite their safety and efficacy

ELSE PRESS RELEASES FROM THIS DATE:

Researchers find way to turn sawdust into gasoline

2014-11-25
Researchers at KU Leuven's Centre for Surface Chemistry and Catalysis have successfully converted sawdust into building blocks for gasoline. Using a new chemical process, they were able to convert the cellulose in sawdust into hydrocarbon chains. These hydrocarbons can be used as an additive in gasoline, or as a component in plastics. The researchers reported their findings in the journal Energy & Environmental Science. Cellulose is the main substance in plant matter and is present in all non-edible plant parts of wood, straw, grass, cotton and old paper. "At the molecular ...

'Dramatic' early phase 1 results for AG-120 in IDH1 mutated AML

2014-11-25
Results presented November 19 by University of Colorado Cancer Center investigator Daniel Pollyea, MD, MS, at the 26th European Organisation for Research and Treatment of Cancer Symposium in Barcelona show "extremely promising" early phase 1 clinical trial results for the investigational drug AG-120 against the subset of patients with acute myeloid leukemia (AML) harboring mutations in the gene IDH1. The finding builds on phase 1 results of a related drug, AG-221, against IDH2 mutations, presented at the most recent meeting of the American Association for Cancer Research. ...

Johns Hopkins scientists link gene to tamoxifen-resistant breast cancers

2014-11-25
After mining the genetic records of thousands of breast cancer patients, researchers from the Johns Hopkins Kimmel Cancer Center have identified a gene whose presence may explain why some breast cancers are resistant to tamoxifen, a widely used hormone treatment generally used after surgery, radiation and other chemotherapy. The gene, called MACROD2, might also be useful in screening for some aggressive forms of breast cancers, and, someday, offering a new target for therapy, says Ben Ho Park, M.D., Ph.D., an associate professor of oncology in the Kimmel Cancer Center's ...

Policing Canada in the 21st century: New policing for new challenges

2014-11-25
A new expert panel report, Policing Canada in the 21st Century: New Policing for New Challenges, released today by the Council of Canadian Academies, details the complexity and global nature of policing in the modern age. Overall, a 12-member Expert Panel determined that safety and security cannot just rest with Canada's policing services. Specialists, public and private security services, and other first responders all have a vital role to play in an interconnected safety and security web. This transition has already begun in Canada and around the world. A central challenge ...

Problem gambling, personality disorders often go hand in hand

2014-11-25
The treatment of people who cannot keep their gambling habits in check is often complicated because they also tend to suffer from personality disorders. So says Meredith Brown of Monash University in Australia, in a review in Springer's Journal of Gambling Studies. Problem gambling creates a multitude of intrapersonal, interpersonal and social difficulties for the roughly 2.3 percent of the population internationally that suffers from this behavior. Previous research has shown that people with gambling problems suffer from a range of psychiatric disorders affecting their ...

One-two punch of drugs better than either alone against colorectal cancer

2014-11-25
Genes make proteins and proteins tell your body's cells what to do: one talks to the next, which talks to the next, and to the next. Like a game of telephone, researchers call these "signaling pathways". Abnormalities in these signaling pathways can cause the growth and survival of cancer cells. Commonly, mutations or rearrangements of genes in the MAPK signaling pathway create cancer's fast growth, and alterations in the PI3K signaling pathway allow cancer cells to survive into virtual immortality. Of course, researchers have extensively targeted these two signaling ...

Why cancer cells grow despite a lack of oxygen

Why cancer cells grow despite a lack of oxygen
2014-11-25
FRANKFURT/GIESSEN. Healthy cells reduce their growth when there is a lack of oxygen (hypoxia). This makes it even more surprising that hypoxia is a characteristic feature of malignant tumours. In two publications in the current edition of the "Nature Communications" journal, researchers from Goethe University and Justus-Liebig-University of Giessen report on how cancer cells succeed at circumventing the genetic program of growth inhibition. It has long been known that PHD proteins (prolyl-hydroxylase domain proteins) play a key role among the regulators of hypoxia. They ...

New device may ease mammography discomfort

2014-11-25
CHICAGO - Researchers have developed a new device that may result in more comfortable mammography for women. According to a study being presented next week at the annual meeting of the Radiological Society of North America (RSNA), standardizing the pressure applied in mammography would reduce pain associated with breast compression without sacrificing image quality. Compression of the breast is necessary in mammography to optimize image quality and minimize absorbed radiation dose. However, mechanical compression of the breast in mammography often causes discomfort and ...

Asymptomatic atherosclerosis linked to cognitive impairment

2014-11-25
CHICAGO - In a study of nearly 2,000 adults, researchers found that a buildup of plaque in the body's major arteries was associated with mild cognitive impairment. Results of the study conducted at the University of Texas (UT) Southwestern Medical Center will be presented next week at the annual meeting of the Radiological Society of North America (RSNA). "It is well established that plaque buildup in the arteries is a predictor of heart disease, but the relationship between atherosclerosis and brain health is less clear," said Christopher D. Maroules, M.D., radiology ...

Scientists could save thousands of pounds with student's DIY microscope

Scientists could save thousands of pounds with students DIY microscope
2014-11-25
Expensive tests for measuring everything from sperm motility to cancer diagnosis have just been made hundreds of thousands of pounds cheaper by a PhD student from Brunel University London who hacked his own microscope. Adam Lynch, from the university's College of Health and Life Sciences, created his own inverted microscope by adapting a cheap instrument he bought online to save himself time and money. The tool is used to measure cell motility - how fast cells move from one place to another - but the high-quality equipment, used to automatically test multiple samples, ...

LAST 30 PRESS RELEASES:

Global cervical cancer vaccine roll-out shows it to be very effective in reducing cervical cancer and other HPV-related disease, but huge variations between countries in coverage

Negativity about vaccines surged on Twitter after COVID-19 jabs become available

Global measles cases almost double in a year

Lower dose of mpox vaccine is safe and generates six-week antibody response equivalent to standard regimen

Personalised “cocktails” of antibiotics, probiotics and prebiotics hold great promise in treating a common form of irritable bowel syndrome, pilot study finds

Experts developing immune-enhancing therapies to target tuberculosis

Making transfusion-transmitted malaria in Europe a thing of the past

Experts developing way to harness Nobel Prize winning CRISPR technology to deal with antimicrobial resistance (AMR)

CRISPR is promising to tackle antimicrobial resistance, but remember bacteria can fight back

Ancient Maya blessed their ballcourts

Curran named Fellow of SAE, ASME

Computer scientists unveil novel attacks on cybersecurity

Florida International University graduate student selected for inaugural IDEA2 public policy fellowship

Gene linked to epilepsy, autism decoded in new study

OHSU study finds big jump in addiction treatment at community health clinics

Location, location, location

Getting dynamic information from static snapshots

Food insecurity is significant among inhabitants of the region affected by the Belo Monte dam in Brazil

The Society of Thoracic Surgeons launches new valve surgery risk calculators

Component of keto diet plus immunotherapy may reduce prostate cancer

New circuit boards can be repeatedly recycled

Blood test finds knee osteoarthritis up to eight years before it appears on x-rays

April research news from the Ecological Society of America

Antimicrobial resistance crisis: “Antibiotics are not magic bullets”

Florida dolphin found with highly pathogenic avian flu: Report

Barcodes expand range of high-resolution sensor

DOE Under Secretary for Science and Innovation visits Jefferson Lab

Research expo highlights student and faculty creativity

Imaging technique shows new details of peptide structures

MD Anderson and RUSH unveil RUSH MD Anderson Cancer Center

[Press-News.org] Few operations for epilepsy despite their safety and efficacy