PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

UNC-Chapel Hill researchers collaborate to develop revolutionary 3-D printing technology

3-D printer is the first to use light and oxygen to synthesize materials from a pool of liquid, reimagining a technology that could bring 3-D printing into mainstream manufacturing

2015-03-17
(Press-News.org) A 3D printing technology developed by Silicon Valley startup, Carbon3D Inc., enables objects to rise from a liquid media continuously rather than being built layer by layer as they have been for the past 25 years, representing a fundamentally new approach to 3D printing. The technology, to appear as the cover article in the March 20 print issue of Science, allows ready-to-use products to be made 25 to 100 times faster than other methods and creates previously unachievable geometries that open opportunities for innovation not only in health care and medicine, but also in other major industries such as automotive and aviation.

Joseph M. DeSimone, professor of chemistry at UNC-Chapel Hill and of chemical engineering at N.C. State, is currently CEO of Carbon3D where he co-invented the method with colleagues Alex Ermoshkin, chief technology officer at Carbon 3D and Edward T. Samulski, also professor of chemistry at UNC. Currently on sabbatical from the University, DeSimone has focused on bringing the technology to market, while also creating new opportunities for graduate students to use the technique for research in materials science and drug delivery at UNC and NCSU.

The technology, called CLIP - for Continuous Liquid Interface Production - manipulates light and oxygen to fuse objects in liquid media, creating the first 3D printing process that uses tunable photochemistry instead of the layer-by-layer approach that has defined the technology for decades. It works by projecting beams of light through an oxygen-permeable window into a liquid resin. Working in tandem, light and oxygen control the solidification of the resin, creating commercially viable objects that can have feature sizes below 20 microns, or less than one-quarter of the width of a piece of paper.

"By rethinking the whole approach to 3D printing, and the chemistry and physics behind the process, we have developed a new technology that can create parts radically faster than traditional technologies by essentially 'growing' them in a pool of liquid," said DeSimone, who revealed the technology at a TED talk on March 16 in the opening session of the conference in Vancouver, British Columbia.

Through a sponsored research agreement between UNC-Chapel Hill and Carbon 3D, the team is currently pursuing advances to the technology, as well as new materials that are compatible with it. CLIP enables a very wide range of material to be used to make 3D parts with novel properties, including elastomers, silicones, nylon-like materials, ceramics and biodegradable materials. The technique itself provides a blueprint for synthesizing novel materials that can further research in materials science.

Rima Janusziewicz and Ashley R. Johnson, graduate students in DeSimone's academic lab, are co-authors on the paper and are working on novel applications in drug delivery and other areas.

"In addition to using new materials, CLIP can allow us to make stronger objects with unique geometries that other techniques cannot achieve, such as cardiac stents personally tailored to meet the needs of a specific patient," said DeSimone. "Since CLIP facilitates 3D polymeric object fabrication in a matter of minutes instead of hours or days, it would not be impossible within coming years to enable personalized coronary stents, dental implants or prosthetics to be 3D printed on-demand in a medical setting."

CLIP's debut coincides with the United Nation designating 2015 as the International Year of Light and Light-Based Technologies, which recognizes important anniversaries of scientific advances enabled with light.

INFORMATION:



ELSE PRESS RELEASES FROM THIS DATE:

Study reveals previously unknown site of anesthetic action

2015-03-17
Anesthetics have been used in surgical procedures for more than 150 years, but the mechanisms by which inhaled anesthesia actually work are poorly understood. Now, researchers at Johns Hopkins Medicine have discovered that anesthetics bind to and interfere with certain proteins in excitatory neurons, which are necessary for these neurons to transmit signals involved in anesthesia and the perception of pain. "Our discovery may be an important component of the mechanism of anesthesia and -- because this particular protein is also involved in neuronal development -- could ...

Joint fluid harbors bacterial clumps after replacement despite pre-surgery antibiotics

2015-03-17
PHILADELPHIA, PA - March 17, 2015- Researchers at Thomas Jefferson University and the National Institutes of Health are building on their research which seeks to understand why joint infections persist despite standards of care designed to stop them. More Americans than ever will receive joint replacements, and with an infection rate of approximately 1 percent, the potential exists for tens of thousands to experience post-operative infection and complications each year. "In this study, we decided to find out if pre-operative, prophylactic antibiotic concentrations in ...

Emerging diseases likely to be more harmful in similar species

2015-03-17
When viruses such as influenza and Ebola jump from one species to another, their ability to cause harm can change dramatically, but research from the University of Cambridge shows that it may be possible to predict the virus's virulence by looking at how deadly it is in closely-related species. A number of emerging infectious diseases - including some of the most deadly outbreaks such as Ebola, SARS and HIV - are the result of humans becoming infected with a pathogen that normally infects another species. The amount of harm caused by a pathogen when it jumps into a new ...

Meta-analysis finds extended DAPT related to increased mortality after DES implantation

2015-03-17
NEW YORK, NY - March 13, 2015 - Data from a meta-analysis published today in The Lancet found that extended duration dual antiplatelet therapy (DAPT) after drug-eluting stent (DES) implantation was associated with significantly higher rates of mortality compared to shorter DAPT. The optimal duration of DAPT has been a matter of debate since the introduction of DES. A meta-analysis using multiple analytical approaches to investigate mortality and other clinical outcomes with different DAPT strategies was conducted. Researchers examined 31,666 patients from 10 randomized ...

Findings from the BRIGHT trial published in JAMA

2015-03-17
NEW YORK, NY - March 16, 2015 - Data from the BRIGHT trial published today in the Journal of the American Medical Association demonstrated that bivalirudin was superior to both heparin monotherapy and heparin plus tirofiban for patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI). Findings were first reported at last year's Transcatheter Cardiovascular Therapeutics (TCT), the annual scientific symposium of the Cardiovascular Research Foundation (CRF). There has been recent controversy surrounding the optimal anticoagulant ...

What's on the menu for young African sawflies?

Whats on the menu for young African sawflies?
2015-03-17
Sawflies belong to the same insect group as wasps, bees and ants. Unlike many of the latter, sawflies seldom make themselves conspicuous to humans, although the young stages (larvae) of some species, nearly all of which feed on plants, sometimes attract attention by damaging these. In a reversal of the pattern found in most insect groups, a larger number of sawfly species occur in regions with a cooler climate, rather than in the tropics. On the other hand, many of the sawflies found in Africa south of the Sahara (the Afrotropical faunal region) belong to genera that ...

Heart valve repair improves emotional wellbeing in patients with mitral regurgitation

2015-03-17
Chicago, March 17, 2015 - Patients with severe mitral regurgitation (MR) often suffer from psycho-emotional symptoms, such as depression and anxiety, but after undergoing mitral valve repair surgery patients experience a marked improvement in emotional and physical wellbeing, according to an article in the March 2015 issue of The Annals of Thoracic Surgery. Key points Patients with severe mitral regurgitation, who had suffered from anxiety and post-traumatic stress symptoms prior to mitral valve surgery, experienced a marked improvement in emotional and physical ...

By land and by sea: Scientists find differences in tanning treatments for materials

2015-03-17
Cod liver oil and willow bark extract used in the tanning of skins for clothing and other products offer notable differences in treatment, a study by a team of scientists shows. Their findings show the promise of a technique that may be used to identify the aging behavior of materials and to examine delicate works of art. The research, which appears in the journal Analytical Chemistry, relies on a method employing nuclear magnetic resonance spectroscopy, or NMR spectroscopy, which reveals the physical and chemical properties of atoms in a given substance, as well as the ...

Spherical nucleic acids set stage for new paradigm in drug development

2015-03-17
A research team led by Northwestern University nanomedicine expert Chad A. Mirkin and Sergei Gryaznov of AuraSense Therapeutics is the first to show spherical nucleic acids (SNAs) can be used as potent drugs to effectively train the immune system to fight disease, by either boosting or dampening the immune response. The initial treatment triggers a cell-specific immune response all over the body. By increasing the body's immune response toward a specific cell type, SNAs could be used to target anything from influenza to different forms of cancer. They also can be used ...

Study finds imaging tool to diagnose heart conditions is more accurate and safer

2015-03-17
New heart imaging technology to diagnose coronary heart disease and other heart disorders is significantly more accurate, less expensive and safer than traditional methods, according to a new study by researchers from the Intermountain Medical Center Heart Institute in Salt Lake City. Researchers at the Intermountain Medical Center Heart Institute compared Single Photon Emission Computed Tomography (SPECT), currently the most commonly used imaging diagnostic tool, with a new imaging technology -- coronary-specific Positron Emission Tomography (cardiac PET/CT). They ...

LAST 30 PRESS RELEASES:

The U-shaped relationship between admission peripheral oxygen saturation and all-cause hospital mortality in acute exacerbation of chronic obstructive pulmonary disease: a retrospective analysis using

New research highlights wide variation in prostate cancer testing between GP practices

Antidepressants linked to faster cognitive decline in dementia

DNA origami suggests route to reusable, multifunctional biosensors

Virginia Tech study reveals that honeybee dance ‘styles’ sway food foraging success

Beehive sensors offer hope in saving honeybee colonies

Award-winning research may unlock universe’s origins

BRCA1 gene mutations may not be key to prostate cancer initiation, as previously thought

Melatonin supplementation may help offset DNA damage linked to night shift work

Common gynaecological disorders linked to raised heart and cerebrovascular disease risk

Nerve fibers in the inner ear adjust sound levels and help compensate for hearing loss in mice, study finds

ECMWF – Europe’s leading centre for weather prediction makes forecast data from AI model available to all

New paper-based device boosts HIV test accuracy from dried blood samples

Pay-for-performance metrics must be more impactful and physician-controlled

GLP-1RAs may offer modest antidepressant effects compared to DPP4is but not SGLT-2is

Performance-based reimbursement increases administrative burden and moral distress, lowers perceived quality of care

Survey finds many Americans greatly overestimate primary care spending

Researchers advance RNA medical discovery decades ahead of schedule

Immune ‘fingerprints’ aid diagnosis of complex diseases in Stanford Medicine study

Ancient beaches testify to long-ago ocean on Mars

Gulf of Mars: Rover finds evidence of ‘vacation-style’ beaches on Mars

MSU researchers use open-access data to study climate change effects in 24,000 US lakes

More than meets the eye: An adrenal gland tumor is more complex than previously thought

Origin and diversity of Hun Empire populations

New AI model measures how fast the brain ages

This new treatment can adjust to Parkinson's symptoms in real time

Bigger animals get more cancer, defying decades-old belief

As dengue spreads, researchers discover a clue to fighting the virus

Teaming up tiny robot swimmers to transform medicine

The Center for Open Science welcomes Daniel Correa and Amanda Kay Montoya to its Board of Directors

[Press-News.org] UNC-Chapel Hill researchers collaborate to develop revolutionary 3-D printing technology
3-D printer is the first to use light and oxygen to synthesize materials from a pool of liquid, reimagining a technology that could bring 3-D printing into mainstream manufacturing