PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Frequent users of emergency care more than twice as likely to die or be admitted

Proactive targeted treatment may help, say researchers

2015-05-08
(Press-News.org) Frequent users of emergency care are more than twice as likely as infrequent users to die, be admitted to hospital, or require other outpatient treatment, concludes an analysis of the available evidence, published online in Emergency Medicine Journal.

The available evidence suggests that frequent users account for up to one in 12 patients seeking emergency department care, and for around one in four of all visits. The authors base their findings on a thorough search of seven electronic databases of relevant research relating to the frequency and outcomes of emergency department use by adults.

Out of a total of more than 4000 potential studies, 31 relevant pieces of research published between 1990 and 2013 were included in the final analysis. Frequent users were variously defined as visiting emergency care departments from four or more times up to 20 times a year.

Among the seven studies looking at deaths, the analysis showed that frequent attenders at emergency care departments were more than twice as likely to die as those who rarely sought emergency care.

Most of the studies included hospital admission as an outcome, and these showed that frequent users were around 2.5 times as likely to be admitted as infrequent users. Ten studies looked at use of other hospital outpatient care, and these showed that frequent users were more than 2.5 times as likely to require at least one outpatient clinic after their visit to the emergency care department.

"Our results suggest that, despite heterogeneity, frequent users are a distinct and high risk group," write the authors, adding that they might benefit from a more targeted proactive approach.

But the lack of any consensus as to what constitutes a frequent user is striking, they emphasise, and this makes it difficult to permit comparison and come up with potentially generalisable recommendations. This needs addressing as a matter of urgency, they say.

INFORMATION:



ELSE PRESS RELEASES FROM THIS DATE:

Dexamethasone may help prevent severe kidney injury following heart surgery

2015-05-08
Highlights Patients who received dexamethasone during heart surgery had about a 2.5-times lower risk of developing kidney failure requiring dialysis compared with those receiving a placebo. The greatest benefits of dexamethasone were seen in patients with pre-existing advanced chronic kidney disease. Acute kidney injury can be a serious complication following heart surgery. Washington, DC (May 7, 2015) -- The anti-inflammatory drug dexamethasone helps prevent serious kidney complications that can arise following heart surgery, according to the results of a ...

30-day wait before tubal sterilization is unjust, say Ob/GYN experts

2015-05-08
Philadelphia, PA, May 7, 2015 - Current U.S. health policy requires Medicaid beneficiaries to wait 30 days before tubal sterilization. Ob/gyn experts argue that this violates health care justice as elective tubal sterilization is readily available to women with a private source of payment. Writing in the American Journal of Obstetrics & Gynecology, they urge obstetricians to advocate for change to eliminate health care injustice in women's access to elective tubal sterilization. One of the most common forms of contraception in the U.S. is tubal sterilization after childbirth, ...

Hip strengthening might ease pain of clogged leg arteries

2015-05-07
San Francisco, May 7, 2015 - Detailed gait analysis reveals that people with clogged leg arteries rely more on muscles in the back of the calf when they walk to compensate for weakness in certain hip muscles, according to a new study presented at the American Heart Association's Arteriosclerosis, Thrombosis and Vascular Biology/Peripheral Vascular Disease Scientific Sessions 2015. This suggests that exercise training to strengthen hip flexor muscles may increase how far patients can walk without calf pain. Peripheral artery disease (PAD) is a narrowing of the arteries ...

Soil security

2015-05-07
A group of leading soil scientists, including the University of Delaware's Donald L. Sparks, has summarized the precarious state of the world's soil resources and the possible ramifications for human security in a paper published Thursday, May 7, in the journal Science. In a review of recent scientific literature, the article, titled "Soil and Human Security in the 21st Century," outlines threats to soil productivity -- and, in turn, food production -- due to soil erosion, nutrient exhaustion, urbanization and climate change. "Soil is our planet's epidermis," said Sparks, ...

Evidence of efficacy of gene therapy in rodents affected by a rare genetic liver disease, Crigler-Najjar syndrome

2015-05-07
Crigler-Najjar syndrome is a rare autosomal recessive disorder caused by mutations in the UGT1A1 gene, which result in the toxic accumulation of bilirubin, a substance made by the liver in the body. Indeed, when the UDP-glucuronosyltransferase 1 isotype A1 (UGT1A1), the enzyme responsible for removing bilirubin, doesn't work, the substance accumulates, causing a severe and chronic jaundice, and becoming toxic for the brain and leading to lethality. Gene therapy has allowed the restoration of an equivalent level of bilirubin to those found in healthy animals Federico ...

Baiting the hook

2015-05-07
Luring longtime and new customers to try online shopping, and retaining them in a competitive and crowded marketplace, is the challenge of the day for established offline retailers. A study of the multichannel UK grocery shopping environment recently yielded insights that will be useful for retailers with an online channel or considering adding one to their customers' options. A team of researchers from Belgium's KU Leuven (University of Leuven), led by doctoral candidate Kristina Melis, investigated purchasing behavior and the adoption of an online grocery shopping ...

Alzheimer protein's structure may explain its toxicity

2015-05-07
Researchers at the University of Illinois at Chicago have determined the molecular structure of one of the proteins in the fine fibers of the brain plaques that are a hallmark of Alzheimer's disease. This molecule, called amyloid beta-42, is toxic to nerve cells and is believed to provoke the disease cascade. The study is online in the journal Nature Structural and Molecular Biology. Knowing the physical structure of the 42 amino acid-long form of amyloid beta in the fibers is key to understanding how it folds up improperly and aggregates into toxic plaques, says Yoshitaka ...

New intervention pioneered at UC Davis helps mothers address depression

2015-05-07
This news release is available in Spanish. (SACRAMENTO, Calif.) -- Researchers at UC Davis have developed a new intervention that identifies potentially depressed mothers and encourages them to seek treatment. The Motivating our Mothers (MOM) program takes a unique approach, relying on pediatricians rather than the mother's doctor for diagnosis. In the study, mothers were given a short survey to assess whether they needed additional care. Those who identified depression symptoms were then coached by a research assistant to seek further help. The program had a remarkable ...

Near-atomic resolution of protein structure by electron microscopy holds promise

Near-atomic resolution of protein structure by electron microscopy holds promise
2015-05-07
A new study shows that it is possible to use an imaging technique called cryo-electron microscopy (cryo-EM) to view, in near-atomic detail, the architecture of a metabolic enzyme bound to a drug that blocks its activity. This advance provides a new path for solving molecular structures that may revolutionize drug development, noted the researchers. The protein imaged in this study was a small bacterial enzyme called beta-galactosidase; the drug to which it was bound is an inhibitor called phenylethyl-beta-D-thiogalactopyranoside (PETG), which fits into a pocket in the ...

Cells amplify messenger RNA levels to set protein levels

2015-05-07
Messenger RNA (mRNA) levels dictate most differences protein levels in fast-growing cells when analyzed using statistical methods that account for noise in the data, according to a new study by researchers from the University of Chicago and Harvard University. The research, published May 7, 2015 in the journal PLOS Genetics, counters widely reported studies arguing that the correlation between mRNA transcript levels and protein levels is relatively low, and that processes acting after mRNA transcription override mRNA levels. Instead, the authors argue, these conclusions ...

LAST 30 PRESS RELEASES:

Research reveals missed opportunities to save George Floyd’s life

HKUST discovers novel elastic alloy achieving 20x temperature change and 90% carnot efficiency in solid-state heat pumping

Early prediction of preterm birth in cell-free RNA may revolutionize prevention strategies

Largest phase 3 trial of novel treatment for hypertension shows promising results

European regulation needed to prevent the birth of children with inherited cancer-causing genetic mutation after sperm donation

Assembly instructions for enzymes

Rice geophysicist Ajo-Franklin wins Reginald Fessenden Award for pioneering work in fiber optic sensing

Research spotlight: New therapeutic approach stops glioblastoma from hijacking the immune system

‘Hopelessly attached’: Scientists discover new 2D material that sticks the landing

Flowers unfold with surprising precision, despite unruly genes

Research spotlight: Study provides a window into public perceptions about technological treatment options for brain conditions

Sound insulation tiles at school help calm crying children #ASA188

More young adults than ever take HIV-prevention medication, but gaps remain

Why are some rocks on the moon highly magnetic? MIT scientists may have an answer

Unique chemistry discovered in critical lithium deposits

Numerical simulations reveal the origin of barred olivine crystals in early solar system

Daytime boosts immunity, scientists find

How marine plankton adapts to a changing world

Charge radius of Helium-3 measured with unprecedented precision

Oral microbiota transmission partially mediates depression and anxiety in newlywed couples

First vascularized model of stem cell islet cells

US excess deaths continued to rise even after the COVID-19 pandemic

Excess US deaths before, during, and after the COVID-19 pandemic

Millions of HealthCare.gov participants face coverage loss due to burdensome reenrollment policies, according to new research

Study: DNA test detects three times more lung pathogens than traditional methods

Modulation of antiviral response in fungi via RNA editing

Global, regional, and national burden of nontraumatic subarachnoid hemorrhage

Earliest use of psychoactive and medicinal plant ‘harmal’ identified in Iron Age Arabia

Nano-scale biosensor lets scientists monitor molecules in real time

Study shows how El Niño and La Niña climate swings threaten mangroves worldwide

[Press-News.org] Frequent users of emergency care more than twice as likely to die or be admitted
Proactive targeted treatment may help, say researchers