PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Visualizing calcified coronary arteries may be wake-up call to change lifestyle

Patients who looked at images were more likely to stop smoking, lose weight and take statins

2015-06-15
(Press-News.org) "It is my coronary artery and my coronary artery calcification and I am facing a real risk and challenge," said one patient.

EuroHeartCare is the official annual meeting of the Council on Cardiovascular Nursing and Allied Professions (CCNAP) of the European Society of Cardiology (ESC). The 2015 meeting is held 14 to 15 June in Dubrovnik, Croatia, in collaboration with the Croatian Association of Cardiology Nurses.

Ms Mols said: "Patients with non-obstructive coronary artery disease and hyperlipidaemia (high blood lipids) urgently need to improve their lifestyles and take lipid-lowering therapy to reduce their risk of future cardiovascular adverse events. Some patients call us after coronary computed tomography angiography (CTA)1 if the result is non-obstructive coronary artery disease. They are afraid of a heart attack and have questions about the prescribed lipid-lowering drugs and how to manage their increased risk."

She added: "When patients receive a new diagnosis of non-obstructive coronary artery disease it might be a good time to motivate them to take their lipid-lowering therapy and adopt a healthy lifestyle. But until now there has not been a study on the impact of showing consecutive patients with atypical angina images of their calcified coronary arteries as a way to stimulate change."

The aim of the current prospective, randomised controlled study was to assess the influence of visualisation of coronary artery calcification in addition to standard information about risk and lifestyle modification on plasma cholesterol concentrations and other risk factors in patients with hyperlipidaemia and a new diagnosis of non-obstructive coronary artery disease.

The study included 189 patients with hyperlipidaemia who had undergone a CTA of their coronary arteries and been diagnosed with non-obstructive coronary artery disease. Patients were prospectively randomised in a 1:1 fashion to the intervention or to standard follow up in general practice which consisted of information about risk and lifestyle modification. Risk factors were measured at baseline and 6 months.

The intervention was a 25 minute consultation with a nurse. The first 15 minutes focused on communication of risk. Patients were shown a CT image of their calcified coronary arteries. The nurse explained the association between coronary artery calcification and the increased risk of future adverse cardiovascular events. The nurse also described the relationship between cardiovascular risk factors and the development of coronary artery calcification. Ten minutes were then devoted to giving advice about statins, aspirin, blood pressure, healthy diet, physical activity and smoking cessation based on ESC prevention guidelines.2,3

After excluding patients who discontinued statin therapy due to side effects (20 in the control group, 22 in the intervention group) the researchers found a significantly greater reduction in plasma total cholesterol concentrations in the intervention group compared to controls (1.71 mmol/L vs. 1.44 mmol/L, p = 0.027).

More patients in the control group continued smoking (22% vs. 9%, p = 0.014) and eating an unhealthy diet (64% vs. 44%, p = 0.005). The intervention group lost 1.5 kg on average while the control group gained an average of 0.5 kg (p = 0.001).There was a tendency towards a higher degree of adherence to statin therapy in the intervention group (p = 0.056).

Ms Mols said: "Seeing their calcified coronary arteries on the CT image was clearly an eye-opener for patients. We received comments such as, 'It is my coronary artery and my coronary artery calcification and I am facing a real risk and challenge'. This may be the wake-up call patients need to take their medication and modify their behaviours to reduce their risk of having a coronary artery event."

She added: "We found that patients who looked at images of their calcified coronary arteries were more likely to stop smoking, lose weight, eat a healthy diet, take recommended statins and reduce their plasma cholesterol levels. The results of our study suggest that visualising their health threat motivates patients to make changes to reduce their risk. A large scale study is needed to confirm the findings and to determine the cost-effectiveness of implementing this intervention in clinical practice."

INFORMATION:



ELSE PRESS RELEASES FROM THIS DATE:

American Thoracic Society issues recommendations on healthy sleep

2015-06-15
The American Thoracic Society has released a policy statement with recommendations for clinicians and the general public on achieving good quality sleep and getting an adequate quantity of sleep. "Sleep plays a vital role in human health, yet there is a lack of sufficient guidance on promoting good sleep health," said Sutapa Mukherjee, MBBS, PhD, chair of the committee that produced the statement. "In this statement, with an eye towards improving public health, we address the importance of good quality sleep with a focus on sleep health in adults and children; the effects ...

New calculations to improve CO2 monitoring from space

2015-06-15
How light of different colours is absorbed by carbon dioxide (CO2) can now be accurately predicted using new calculations developed by a UCL-led team of scientists. This will help climate scientists studying Earth's greenhouse gas emissions to better interpret data collected from satellites and ground stations measuring CO2. By improving the understanding of how much radiation CO2 absorbs, uncertainties in modelling climate change will be reduced and more accurate predictions can be made about how much Earth is likely to warm over the next few decades. Previous methods ...

Blood antibodies may predict HPV-positive oropharyngeal cancer survival

2015-06-15
Background: According to Sturgis, the incidence of HPV-positive oropharyngeal carcinoma has increased dramatically in recent years. Although patients with HPV-positive disease have a better prognosis than those with HPV-negative disease, researchers are still seeking a better understanding of what group of patients is more likely to respond to treatment. How the Study Was Conducted: Sturgis and colleagues used blood samples from 209 patients with previously untreated oropharyngeal carcinoma, including 96 who had confirmed HPV-positive disease, and screened the samples ...

ALK1 protein may play a role in breast cancer metastasis

2015-06-15
Background: Pietras said that although prognosis for breast cancer is relatively good when detected in its early stages, metastatic disease is the cause of 90 percent of all cancer-related deaths. Therefore, learning more about the metastatic process and finding new cures to inhibit disease spread is at the center of clinical attention. He explained that in order for a tumor to spread, a cancer cell must detach and traverse the vascular wall to escape into the blood stream, exit the vasculature to enter the metastatic site, and colonize the new tissue. The fact that ...

Endometriosis associated with a greater risk of complications in pregnancy

2015-06-15
Lisbon, 15 June 2015: Women with endometriosis are at an increased risk of miscarriage and ectopic pregnancy, according to results of a huge nationwide study presented today. Moreover, women with a history of endometriosis whose pregnancies progressed beyond 24 weeks were found to be at a higher than average risk of complications, including haemorrhage (ante- and postpartum) and preterm birth. "These results indicate that endometriosis predisposes women to an increased risk of early pregnancy loss and later pregnancy complications," said the study's first author Dr Lucky ...

Lack of evidence on how to care for hip fracture patients with dementia

2015-06-15
Medical guidance on how to care for elderly people with dementia following a hip fracture is 'sadly lacking' according to researchers at the University of East Anglia. Almost half of all people who suffer hip fractures also have dementia. But a Cochrane Review published today reveals there is no conclusive evidence on how to care for this particularly vulnerable group. The review, which was funded by the National Institute for Health Research (NIHR), highlights an urgent need for better research into what strategies improve post-operative care - both within hospital ...

Power of the media's impact on medicine use revealed

2015-06-14
More than 60,000 Australians are estimated to have reduced or discontinued their use of prescribed cholesterol-lowering statin medications following the airing of a two-part series critical of statins by ABC TV's science program, Catalyst, a University of Sydney study reveals in the latest Medical Journal of Australia. The analysis of the Pharmaceutical Benefits Scheme medication records of 191,000 people revealed that there was an immediate impact after Catalyst was aired in October 2013, with 14,000 fewer people dispensed statins per week than expected. "In the eight ...

One in 5 young VTE patients require psychotropic drugs within 5 years

2015-06-14
EuroHeartCare is the official annual meeting of the Council on Cardiovascular Nursing and Allied Professions (CCNAP) of the European Society of Cardiology (ESC). The 2015 meeting is held 14 to 15 June in Dubrovnik, Croatia, in collaboration with the Croatian Association of Cardiology Nurses. Ms Arbjerg Højen said: "Young VTE patients are scared of having another VTE and of dying. We treat these patients in our Thrombosis Research Unit and have seen how anxious and mentally unwell they can be, even a long time after the VTE occurs. They are troubled and have a hard ...

Patients with primary hand OA should not be prescribed hydroxychloroquine

2015-06-13
Rome, Italy, 13 June 2015: The results of an interventional trial presented today at the European League Against Rheumatism Annual Congress (EULAR 2015) showed that use of the disease-modifying anti-rheumatic drug hydroxychloroquine for 24 weeks did not diminish mild-moderate pain from primary hand osteoarthritis (OA). Furthermore, treatment did not improve overall physical, social and emotional wellbeing. These findings suggest that hydroxychloroquine should no longer be routinely prescribed for patients with this form of arthritis. OA is the most common type of arthritis, ...

Dose reduction strategy can substantially reduce high cost of TNF inhibitor therapy in RA

2015-06-13
Rome, Italy, 13 June 2015: The results of a study presented today at the European League Against Rheumatism Annual Congress (EULAR 2015) showed that, in rheumatoid arthritis (RA) patients, a good clinical response to maintenance treatment with a tumour necrosis factor inhibitor (TNFi) was maintained even when the dose was reduced by one-third. Reducing the TNFi dose by two-thirds resulted in more flares (exacerbations of symptoms and signs) but these subsided when the higher dose of TNFi was restarted, and did not adversely affect subsequent progression of any disability. ...

LAST 30 PRESS RELEASES:

Study questions water safety beliefs

Bacteria ‘pills’ could detect gut diseases — without the endoscope

National Cancer Institute grants support efforts to understand how fluid flow drives deadly brain cancer

New global satellite dataset for humanitarian routing and tracking infrastructure change

Australia’s middle-aged are the engine room of the nation but many risk burnout: Report

Why top firms paradoxically fire good workers

Investigating lithium’s potential role in slowing cognitive decline in Alzheimer’s disease

Wiley expands spectral libraries with major updates to IR, Raman, and LC-MS collections

Phase 2 clinical trial results show potential to shorten TB treatment time

UC San Diego researchers expand virus-based treatment options for antibiotic-resistant infections

New magnetic component discovered in the faraday effect after nearly two centuries

AI tool spots blood cell abnormalities missed by doctors

People in isolated cities in Africa suffer more violence against civilians

New antibodies developed that can inhibit inflammation in autoimmune diseases

Global and European experts convene in Warsaw for Europe’s leading public health conference on infectious diseases

How do winter-active spiders survive the cold?

Did US cities’ indoor vaccine mandates affect COVID-19 vaccination rates and outcomes?

How does adoption of artificial intelligence affect employees’ job satisfaction?

Can social media help clarify the threat domestic cats pose to insect and spider populations?

All-you-can-eat: Young adults and ultra-processed foods

MRC Laboratory of Medical Sciences (LMS) awarded £1 million to boost life science partnerships in White City

KIMM launches initiative to establish a regional hub for mechanical researcher in Asia

AMI warns that the threat of antimicrobial resistance in viruses and other pathogens cannot be underestimated

As ‘California sober’ catches on, study suggests cannabis use reduces short-term alcohol consumption

Working with local communities to manage green spaces could help biodiversity crisis, new study finds

Parental monitoring is linked to fewer teen conduct problems despite genetic risk

From stadiums to cyberspace: How the metaverse will redefine sports fandom 

The hidden rule behind ignition — An analytic law governing multi-shock implosions for ultrahigh compression

Can AI help us predict earthquakes?

Teaching models to cope with messy medical data

[Press-News.org] Visualizing calcified coronary arteries may be wake-up call to change lifestyle
Patients who looked at images were more likely to stop smoking, lose weight and take statins