PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Older patients with spinal cord injury: Surgery less likely than for younger patients

2015-07-06
(Press-News.org) Older patients with traumatic spinal cord injury are less likely than younger patients to receive surgical treatment and experience a significant lag between injury and surgery, according to new research in CMAJ (Canadian Medical Association Journal)

The number of people with traumatic spinal cord injury over age 70 is increasing, and it is projected that people in this age group will eventually make up the majority of those with new spinal cord injuries. Currently, most spinal cord injuries occur in people aged 16 to 30 years.

To determine whether patients over age 70 with spinal cord injury were managed differently and had different outcomes, Canadian researchers looked at data from the Rick Hansen Spinal Cord Injury Registry for 1440 people in Canada who had a traumatic spinal cord injury. Of the total, 167 (11.6 %) were aged 70 years or older. These patients were more likely than younger patients to have been injured from falling (83.1% v. 37.4%). Younger patients were more likely to present with severe injuries resulting in paralysis below the trauma site; older patients had less severe injuries.

There were significant delays in treating older patients who arrived at participating acute care centres.

"Older patients experienced a triage delay (time of injury to arrival at a participating acute care centre) that was twice that of younger patients," writes Dr. Henry Ahn, St. Michael's Hospital, Toronto, Ontario, with coauthors. "This may have been due to delays in recognizing their less severe injuries, or may reflect a potential age-related therapeutic bias."

Older patients were also significantly more likely than younger patients to die from a traumatic spinal cord injury.

"The significant differences in injury-related characteristics, timing of surgery and outcomes between older and younger patients necessitate rethinking the management of traumatic spinal cord injury among older patients," say the authors. Reducing surgical delays for traumatic spinal cord injury, regardless of patient age, may help maximize neurologic improvement and avoid adverse events associated with prolonged immobilization such as pneumonia.

The researchers suggest that developing policies with mandated time frames for treatment and management of spinal cord injuries, similar to those for hip fractures, could improve care and outcomes for older patients.

INFORMATION:



ELSE PRESS RELEASES FROM THIS DATE:

Mass. General team generates therapeutic nitric oxide from air with an electric spark

Mass. General team generates therapeutic nitric oxide from air with an electric spark
2015-07-06
Treatment with inhaled nitric oxide (NO) has proven to be life saving in newborns, children and adults with several dangerous conditions, but the availability of the treatment has been limited by the size, weight and complexity of equipment needed to administer the gas and the therapy's high price. Now a research team led by the Massachusetts General Hospital (MGH) physician who pioneered the use of inhaled nitric oxide has developed a lightweight, portable system that produces NO from the air by means of an electrical spark. The investigators describe their invention in ...

Uncovering the mechanism of our oldest anesthetic

2015-07-06
CAMBRIDGE, MA -- Nitrous oxide, commonly known as "laughing gas," has been used in anesthesiology practice since the 1800s, but the way it works to create altered states is not well understood. In a study published this week in Clinical Neurophysiology, MIT researchers reveal some key brainwave changes among patients receiving the drug. For a period of about three minutes after the administration of nitrous oxide at anesthetic doses, electroencephalogram (EEG) recordings show large-amplitude slow-delta waves, a powerful pattern of electrical firing that sweeps across ...

How to rule a gene galaxy: A lesson from developing neurons

How to rule a gene galaxy: A lesson from developing neurons
2015-07-06
The human organism contains hundreds of distinct cell types that often differ from their neighbours in shape and function. To acquire and maintain its characteristic features, each cell type must express a unique subset of genes. Neurons, the functional units of our brain, develop through differentiation of neuronal precursors, a process that depends on coordinated activation of hundreds and possibly thousands of neuron-specific genes. A new study published in Nature Communications by researchers from the MRC Centre for Developmental Neurobiology (MRC CDN) at IoPPN, carried ...

New paradigm for treating 'inflammaging' and cancer

2015-07-06
Intermittent dosing with rapamycin selectively breaks the cascade of inflammatory events that follow cellular senescence, a phenomena in which cells cease to divide in response to DNA damaging agents, including many chemotherapies. The finding, published in Nature Cell Biology, shows that once disrupted, it takes time for the inflammatory loop to reestablish, providing proof-of-principal that intermittent dosing could provide a way to reap the benefits of rapamycin, an FDA-approved drug that extends lifespan and healthspan in mice, while lessening safety issues associated ...

Extra DNA acts as a 'spare tire' for our genomes

2015-07-06
Carrying around a spare tire is a good thing -- you never know when you'll get a flat. Turns out we're all carrying around "spare tires" in our genomes, too. Today, in ACS Central Science, researchers report that an extra set of guanines (or "G"s) in our DNA may function just like a "spare" to help prevent many cancers from developing. Various kinds of damage can happen to DNA, making it unstable, which is a hallmark of cancer. One common way that our genetic material can be harmed is from a phenomenon called oxidative stress. When our bodies process certain chemicals ...

Risk of interbreeding due to climate change lower than expected

2015-07-06
One of the questions raised by climate change has been whether it could cause more species of animals to interbreed. Two species of flying squirrel have already produced mixed offspring because of climate change, and there have been reports of a hybrid polar bear and grizzly bear cub (known as a grolar bear, or a pizzly). "Climate change is causing species' ranges to shift, and that could bring a lot of closely related species into contact," said Meade Krosby, a research scientist in the University of Washington's Climate Impacts Group. She is the lead author of a ...

Detecting more small cancers in screening mammography suggests overdiagnosis

2015-07-06
Screening mammography was associated with increased diagnosis of small cancers in a study across U.S. counties but not with significant changes in breast cancer deaths or a decreased incidence of larger breast cancers, which researchers suggest may be the result of overdiagnosis, according to an article published online by JAMA Internal Medicine. The goal of screening mammography is to reduce breast cancer death by detecting and treating cancer early in the course of the disease. If screening detects tumors early, the diagnosis of smaller and more treatable cancers should ...

Survey finds many physicians, clinicians work sick despite risk to patients

2015-07-06
Many physicians and advanced practice clinicians, including registered nurse practitioners, midwives and physician assistants, reported to work while being sick despite recognizing this could put patients at risk, according to the results of a small survey published online by JAMA Pediatrics. Health-care associated infections can lead to substantial illness and death and excess costs. This is especially true for immunocompromised patients and others at high risk, including neonates. However, a gap in knowledge exists about the reasons why attending physicians and advanced ...

Increased risk of complications, death during delivery for women with epilepsy

2015-07-06
A small fraction of pregnancies occur in women with epilepsy but a new study suggests those women may be at higher risk for complications and death during delivery, according to an article published online by JAMA Neurology. Between 0.3 percent and 0.5 percent of all pregnancies occur in women with epilepsy. However, there is inadequate data on obstetrical outcomes so the risk of adverse outcomes and death in this population of women remains largely unquantified. Sarah C. MacDonald, B.Sc., of the Harvard T.H. Chan School of Public Health, Boston, and coauthors looked ...

Cognitive behavioral therapy for insomnia with psychiatric, medical conditions

2015-07-06
Cognitive behavioral therapy is a widely used nonpharmacologic treatment for insomnia disorders and an analysis of the medical literature suggests it also can work for patients whose insomnia is coupled with psychiatric and medical conditions, according to an article published online by JAMA Internal Medicine. Previous meta-analyses have suggested that cognitive behavioral therapy for insomnia can improve sleep, although many of these studies excluded individuals with co-existing psychiatric and medical conditions. Jason C. Ong, Ph.D., of Rush University Medical Center, ...

LAST 30 PRESS RELEASES:

Towards tailor-made heat expansion-free materials for precision technology

New research delves into the potential for AI to improve radiology workflows and healthcare delivery

Rice selected to lead US Space Force Strategic Technology Institute 4

A new clue to how the body detects physical force

Climate projections warn 20% of Colombia’s cocoa-growing areas could be lost by 2050, but adaptation options remain

New poll: American Heart Association most trusted public health source after personal physician

New ethanol-assisted catalyst design dramatically improves low-temperature nitrogen oxide removal

New review highlights overlooked role of soil erosion in the global nitrogen cycle

Biochar type shapes how water moves through phosphorus rich vegetable soils

Why does the body deem some foods safe and others unsafe?

Report examines cancer care access for Native patients

New book examines how COVID-19 crisis entrenched inequality for women around the world

Evolved robots are born to run and refuse to die

Study finds shared genetic roots of MS across diverse ancestries

Endocrine Society elects Wu as 2027-2028 President

Broad pay ranges in job postings linked to fewer female applicants

How to make magnets act like graphene

The hidden cost of ‘bullshit’ corporate speak

Greaux Healthy Day declared in Lake Charles: Pennington Biomedical’s Greaux Healthy Initiative highlights childhood obesity challenge in SWLA

Into the heart of a dynamical neutron star

The weight of stress: Helping parents may protect children from obesity

Cost of physical therapy varies widely from state-to-state

Material previously thought to be quantum is actually new, nonquantum state of matter

Employment of people with disabilities declines in february

Peter WT Pisters, MD, honored with Charles M. Balch, MD, Distinguished Service Award from Society of Surgical Oncology

Rare pancreatic tumor case suggests distinctive calcification patterns in solid pseudopapillary neoplasms

Tubulin prevents toxic protein clumps in the brain, fighting back neurodegeneration

Less trippy, more therapeutic ‘magic mushrooms’

Concrete as a carbon sink

RESPIN launches new online course to bridge the gap between science and global environmental policy

[Press-News.org] Older patients with spinal cord injury: Surgery less likely than for younger patients