PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Melon genome study reveals recent impacts of breeding

2015-07-15
(Press-News.org) The first comprehensive genome analyses of 7 melon varieties was completed by a research team led by Josep Casacuberta, Jordi Garcia-Mas and Sebastian Ramos-Onsins, providing breeders new knowledge important for understanding phenotypic variability and helping increasing plant quality yields by selective breeding. The findings were published in the advanced online edition of Molecular Biology and Evolution.

The researchers sought to bridge the gap between expanding the genetic knowledge of melons and understanding important traits such as flavor, size and water use.

The study is the first comprehensive analysis of genetic diversity in melon, and describes more than 4.3 million single sequence DNA variants (SNPs), together with an important number of structural variants including deletions, inversions, duplications, and mobile element movements, The team proved that highly cultivated and bred lines show the least diversity, with wild melons being the most diverse. Similar studies of corn, rice, and soybeans have shown that the most farmed and domesticated varieties show the least genetic variability.

The study also revealed in great detail, the genomic architecture of the melon genome (which the researcher dub "melonomics"- see melonomics.net). Overall, they found 902 genes that may be affected by DNA structural variations, with 53 genes putatively involved in disease resistance (29), cell-wall metabolism (10), aroma volatiles metabolism (9), sugar metabolism (4) and carotenoid biosynthesis (1).

The mobile elements, gene-hopping structures called transposons, have been very active during recent melon evolution, and the study reports on a number of transposon insertions that may be linked to the variability of important agronomic traits, even between two closely related elite lines.

The melon genome as a whole has evolved under negative evolutionary selective pressure, removing deleterious traits over time to improve fitness and adaptation.

"This study reveals the high plasticity of the melon genome, and paves the way for future analyses to address melon breeding goals, such as increasing the quality of the fruit, or resistance against pests and diseases. On a more general perspective, studies such as this one will be needed to breed new plant varieties allowing to respond to the challenges in agriculture, including a growing human population, land and water scarcity, and the future impact of climate change," said Casacuberta.

INFORMATION:



ELSE PRESS RELEASES FROM THIS DATE:

Damage to key brain region important in predicting cognitive function after pediatric TBI

2015-07-15
Disruptions in a key brain region can explain the varied outcomes after a traumatic brain injury (TBI) in children and adolescents, according to research published July 15 in The Journal of Neuroscience. Post-injury outcomes vary widely, and injury severity can only explain some of this variance. Combining data from brain imaging and recording, researchers at the University of Southern California and UCLA found that disruptions in the structure and function of a brain region called the corpus callosum could explain the variance in cognitive outcomes. TBI is the leading ...

Why kids' recovery times vary widely after brain injury

2015-07-15
Why do some youngsters bounce back quickly from a traumatic brain injury, while others suffer devastating side effects for years? New UCLA/USC research suggests that damage to the fatty sheaths around the brain's nerve fibers--not injury severity-- may explain the difference. Published in the July 15 edition of the Journal of Neuroscience, the finding identifies possible biomarkers that physicians could use to predict higher-risk patients who require closer monitoring. The study is the first to combine imaging scans with recording of the brain's electrical activity ...

Density-near-zero acoustical metamaterial made in China

Density-near-zero acoustical metamaterial made in China
2015-07-14
WASHINGTON, DC, July 14, 2015 -- When a sound wave hits an obstacle and is scattered, the signal may be lost or degraded. But what if you could guide the signal around that obstacle, as if the interfering barrier didn't even exist? Recently, researchers at Nanjing University in China created a material from polyethylene membranes that does exactly that. Their final product, described this week in the Journal of Applied Physics, from AIP Publishing, was an acoustical "metamaterial" with an effective density near zero (DNZ). This work could help to endow a transmission ...

Researchers discover way to assess future literacy challenges

2015-07-14
A quick biological test may be able to identify children who have literacy challenges or learning disabilities long before they learn to read, according to new research from Northwestern University. The study, publishing in the Open Access journal PLOS Biology on July 14th, centers on the child's ability to decipher speech -- specifically consonants -- in a chaotic, noisy environment. Preliterate children whose brains inefficiently process speech against a background of noise are more likely than their peers to have trouble with reading and language development when ...

Investigational drug prevents life-threatening side effects of kidney disease treatment

2015-07-14
A yearlong study of more than 300 patients found that the investigational drug patiromer can reduce elevated blood-potassium levels--a common side effect of drugs essential in the treatment of chronic diabetic kidney disease. The drug, given in this trial at one of four doses based on disease severity, returned blood potassium levels to normal when measured at four weeks and kept them under control for one year, the length of the trial. By quickly bringing potassium levels back to normal and keeping them there, patiromer can prevent life-threatening adverse events. The ...

New guidelines for statin eligibility improve prediction of cardiovascular risk

2015-07-14
The new guidelines for determining whether patients should begin taking statins to prevent cardiovascular disease issued in 2013 by the American College of Cardiology (ACC) and the American Heart Association (AHA) are more accurate and more efficient than an earlier set of guidelines in assigning treatment to adults at increased risk for cardiovascular events - including heart attacks and strokes - and identifying those whose low risk rules out the need to take statins. In their paper appearing in the July 15 issue of JAMA, a team led by Massachusetts General Hospital (MGH) ...

Accuracy of newer cholesterol guidelines in identifying increased risk of CVD events

2015-07-14
An examination of the 2013 guidelines for determining statin eligibility, compared to guidelines from 2004, indicates that they are associated with greater accuracy and efficiency in identifying increased risk of cardiovascular disease (CVD) events and presence of subclinical coronary artery disease, particularly in individuals at intermediate risk, according to a study in the July 14 issue of JAMA. The 2013 American College of Cardiology/American Heart Association (ACC/AHA) guidelines for the management of blood cholesterol represent a shift in the treatment approach ...

Study examines cost-effectiveness of newer cholesterol guidelines

2015-07-14
A microsimulation model-based analyses suggests that the health benefits associated with the 10-year atherosclerotic cardiovascular disease risk threshold of 7.5 percent or higher used in the 2013 ACC-AHA cholesterol guidelines are worth the additional costs required to achieve these health gains, and that a more lenient threshold might also be cost-effective, according to a study in the July 14 issue of JAMA. In November 2013 the American College of Cardiology and the American Heart Association (ACC/AHA) released new recommendations to guide statin treatment initiation ...

Drug provides improvement for diabetic kidney disease patients with high potassium levels

2015-07-14
Among patients with diabetic kidney disease and hyperkalemia (elevated potassium levels in the blood), a potentially life-threatening condition, those who received the new drug patiromer, twice daily for four weeks, had significant decreases in potassium levels which lasted through one year, according to a study in the July 14 issue of JAMA. Patients at the highest risk for hyperkalemia are those taking renin-angiotensin-aldosterone system (RAAS) inhibitors with stage 3 or greater chronic kidney disease (CKD) who also have diabetes mellitus, heart failure, or both. Because ...

Few states require HPV vaccine

2015-07-14
An examination of state vaccination requirements for adolescents finds that the human papillomavirus (HPV) vaccine is currently required in only two states, many fewer than another vaccine associated with sexual transmission (hepatitis B) and another primarily recommended for adolescents (meningococcal conjugate), according to a study in the July 14 issue of JAMA. Eight years after HPV vaccines were first recommended in the United States, vaccination coverage is substantially below the Healthy People 2020 target of 80 percent. Data from the U.S. Centers for Disease Control ...

LAST 30 PRESS RELEASES:

Discovery of a new superfluid phase in non-Hermitian quantum systems

Codes in the cilia: New study maps how Cilk1 and Hedgehog levels sculpt tooth architecture

Chonnam National University researchers develop novel virtual sensor grid method for low-cost, yet robust, infrastructure monitoring

Expanded school-based program linked to lower youth tobacco use rates in California

TV depictions of Hands-Only CPR are often misleading

What TV gets wrong about CPR—and why it matters for saving lives

New study: How weight loss benefits the health of your fat tissue

Astronomers surprised by mysterious shock wave around dead star

‘Death by a thousand cuts’: Young galaxy ran out of fuel as black hole choked off supplies

Glow with the flow: Implanted 'living skin' lights up to signal health changes

Compressed data technique enables pangenomics at scale

How brain waves shape our sense of self

Whole-genome sequencing may optimize PARP inhibitor use

Like alcohol units, but for cannabis – experts define safer limits

DNA testing of colorectal polyps improves insight into hereditary risks

Researchers uncover axonal protein synthesis defect in ALS

Why are men more likely to develop multiple myeloma than women?

Smartphone-based interventions show promise for reducing alcohol and cannabis use: New research

How do health care professionals determine eligibility for MAiD?

Microplastics detected in rural woodland 

JULAC and Taylor & Francis sign open access agreement to boost the impact of Hong Kong research

Protecting older male athletes’ heart health 

KAIST proposes AI-driven strategy to solve long-standing mystery of gene function

Eye for trouble: Automated counting for chromosome issues under the microscope

The vast majority of US rivers lack any protections from human activities, new research finds

Ultrasound-responsive in situ antigen "nanocatchers" open a new paradigm for personalized tumor immunotherapy

Environmental “superbugs” in our rivers and soils: new one health review warns of growing antimicrobial resistance crisis

Triple threat in greenhouse farming: how heavy metals, microplastics, and antibiotic resistance genes unite to challenge sustainable food production

Earthworms turn manure into a powerful tool against antibiotic resistance

AI turns water into an early warning network for hidden biological pollutants

[Press-News.org] Melon genome study reveals recent impacts of breeding