PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Study finds Dense Breast Notification legislation has not met all desired goals

2021-01-11
(Press-News.org) (Boston)--Little previous research has examined the effects of Dense Breast Notifications (DBNs), but a new study suggests the legislatively required notifications have achieved partial success: women living in states in which in DBNs are mandated had higher rates of being informed about personal breast density and of having had breast density discussions with providers, though rates were low overall. DBNs are a written notification to a woman after a mammogram with information about breast density. The goal is to motivate her to speak with her doctor about her personal risk and determine if supplemental screening for breast cancer is appropriate. DBNs are mandated in more than 38 states and the Food Drug Administration (FDA) is developing standardized language for a federal/nationwide notification.

Prior findings from these same researchers at Boston University School of Medicine (BUSM) showed many states' DBNs are written at a higher literacy level than women residing in that state, which suggests that some women may find it hard to understand the notifications. They have now conducted one of the first national surveys to ask women about their reactions to these notifications and to understand their knowledge, awareness and plans about breast density while examining whether these findings vary among women of varying race/ethnicity, income, and health literacy levels.

In this new study, the researchers investigated whether there were differential breast density awareness, knowledge or discussions among women residing in states with and without DBN legislation or based on sociodemographic characteristics.

Although the study did show that DBN laws are associated with more women receiving information about personal breast density and increased likelihood of having a discussion with a healthcare provider about breast density, women of color, those with lower incomes and those with lower health literacy were generally less likely to have received personal breast density information or to speak with their providers. However, while DBN laws were not generally associated with differences in women's knowledge about risks associated with breast density, Hispanic, lower income, and low health literacy women had less knowledge regarding density's tendency to mask cancers on mammograms, and were less likely to recognize the increased breast cancer risk.

"These findings suggest that 'one size does not fit all' when breast density information is conveyed and suggests that the message or the mode of dissemination may need to be tailored for different populations to achieve knowledge equity," explained corresponding author Nancy Kressin, PhD, professor of medicine at BUSM.

Given that women in DBN states were twice as likely to speak with their doctors, the researchers believe physicians seem a natural conduit for tailored discussions that meet each woman's needs. However, Kressin points out that prior studies have shown that for this approach to be most effective, further physician education will be needed.

INFORMATION:

These findings appear online in the Journal of the American College of Radiology.

Funding for this study was provided by the American Cancer Society and the National Cancer Institute.



ELSE PRESS RELEASES FROM THIS DATE:

Scientists make sustainable polymer from sugars in wood

2021-01-11
Scientists from the University of Bath have made a sustainable polymer using the second most abundant sugar in nature, xylose. Not only does the new nature-inspired material reduce reliance on crude oil products, but its properties can also be easily controlled to make the material flexible or crystalline. The researchers, from the University's Centre for Sustainable and Circular Technologies, report the polymer, from the polyether family, has a variety of applications, including as a building block for polyurethane, used in mattresses and shoe soles; as a bio-derived alternative to polyethylene glycol, a chemical widely used in bio-medicine; or to polyethylene oxide, ...

Using light to revolutionize artificial intelligence

Using light to revolutionize artificial intelligence
2021-01-11
An international team of researchers, including Professor END ...

Link between driver of ovarian cancer and metabolism opens up new therapeutic strategies

Link between driver of ovarian cancer and metabolism opens up new therapeutic strategies
2021-01-11
PHILADELPHIA -- (Jan. 11, 2020) -- Mutations that inactivate the ARID1A gene in ovarian cancer increase utilization of the glutamine amino acid making cancer cells dependent on glutamine metabolism, according to a study by The Wistar Institute published online in Nature Cancer. Researchers also showed that pharmacologic inhibition of glutamine metabolism may represent an effective therapeutic strategy for ARID1A-mutant ovarian cancer. Up to 60% of ovarian clear cell carcinomas (OCCC) have inactivating mutations in the ARID1A tumor suppressor gene. These ...

Oncotarget: Targeted lymphodepletion with a CD45-directed antibody radioconjugate

Oncotarget: Targeted lymphodepletion with a CD45-directed antibody radioconjugate
2021-01-11
Oncotarget recently published "Targeted lymphodepletion with a CD45-directed antibody radioconjugate as a novel conditioning regimen prior to adoptive cell therapy" which reported that Chimeric antigen receptor T cell therapies, and adoptive cell therapy in general, represent one of the most promising anti-cancer strategies. In contrast to relatively non-specific chemotherapy-derived lymphodepletion, targeted lymphodepletion with radioimmunotherapy directed to CD45 may be a safer and more effective alternative to target and deplete immune cells. Here the authors describe the results ...

Elusive link between seizures, cell signaling protein ID'd in zebrafish

Elusive link between seizures, cell signaling protein IDd in zebrafish
2021-01-11
For the brain to learn, retain memories, process sensory information, and coordinate body movements, its groups of nerve cells must generate coordinated electrical signals. Disorder in synchronous firing can impair these processes and, in extreme cases, lead to seizures and epilepsy. Synchrony between neighboring neurons depends on the protein connexin 36, an essential element of certain types of synaptic connections that, unlike classical chemical synapses, pass signals between neurons through direct electrical connections. For more than 15 years, scientists have debated the tie between connexin 36 and epilepsy. Now, a team of Virginia Tech scientists led by Yuchin Albert Pan, an associate professor at the Fralin Biomedical Research ...

Instead of pushing students entrepreneurship, they should be helped to make a better decision

2021-01-11
Many policymakers and educational institutions hope to boost their economies by stimulating students' entrepreneurial intentions. To date, most research concluded that entrepreneurship education could increase these intentions by improving the image that students have of entrepreneurship as a career option, making them see how their environment can help them become entrepreneurs or increasing their self-confidence regarding their entrepreneurial skills. However, recent studies show that even if these goals are achieved, students' entrepreneurial intentions often ...

Rice 'flashes' new 2D materials

Rice flashes new 2D materials
2021-01-11
HOUSTON - (Jan. 11, 2021) - Rice University scientists have extended their technique to produce graphene in a flash to tailor the properties of other 2D materials. The labs of chemist James Tour and materials theorist Boris Yakobson reported in the American Chemical Society's ACS Nano they have successfully "flashed" bulk amounts of 2D dichalcogenides, changing them from semiconductors to metallics. Such materials are valuable for electronics, catalysis and as lubricants, among other applications. The process employs flash Joule heating -- using an electrical charge to dramatically raise the material's temperature -- to convert semiconducting molybdenum disulfide and tungsten disulfide. The duration of the pulse and select additives can also control the now-metallic products' ...

Post-surgical patch releases non-opioid painkiller directly to the wound

2021-01-11
DURHAM, N.C. - A Duke-led team of scientists has developed a bio-compatible surgical patch that releases non-opioid painkillers directly to the site of a wound for days and then dissolves away. The polymer patch provides a controlled release of a drug that blocks the enzyme COX-2 (cyclooxygenase-2,) which drives pain and inflammation. The study appears Jan. 10, 2021 in the Journal of Controlled Release. When they started "We were making hernia meshes and different antimicrobial films," said Matthew Becker, the Hugo L. Blomquist professor chemistry at Duke, and last author on the paper. "We thought you could potentially put pain drugs or anesthetics in the film if you ...

Cracking the code of a shapeshifting protein

2021-01-11
A shapeshifting immune system protein called XCL1 evolved from a single-shape ancestor hundreds of millions of years ago. Now, researchers at the Medical College of Wisconsin (MCW) discovered the molecular basis for how this happened. In the process they uncovered principles that scientists can use to design purpose-built nanoscale transformers for use as biosensors, components of molecular machines, and even therapeutics. The findings were published today in Science. The primary and senior authors of the manuscript, respectively, are MCW researchers Acacia Dishman, MD-PhD student, and Brian Volkman, PhD, professor of biochemistry. Molecular switches can be used to detect cancer, construct nanoscale machines, and even build cellular computers. ...

Study shows tweaking one layer of atoms on a catalyst's surface can make it work better

Study shows tweaking one layer of atoms on a catalysts surface can make it work better
2021-01-11
Scientists crafting a nickel-based catalyst used in making hydrogen fuel built it one atomic layer at a time to gain full control over its chemical properties. But the finished material didn't behave as they expected: As one version of the catalyst went about its work, the top-most layer of atoms rearranged to form a new pattern, as if the square tiles that cover a floor had suddenly changed to hexagons. But that's ok, they reported today, because understanding and controlling this surprising transformation gives them a new way to turn catalytic activity on and off and make good catalysts ...

LAST 30 PRESS RELEASES:

Microplastics detected in rural woodland 

JULAC and Taylor & Francis sign open access agreement to boost the impact of Hong Kong research

Protecting older male athletes’ heart health 

KAIST proposes AI-driven strategy to solve long-standing mystery of gene function

Eye for trouble: Automated counting for chromosome issues under the microscope

The vast majority of US rivers lack any protections from human activities, new research finds

Ultrasound-responsive in situ antigen "nanocatchers" open a new paradigm for personalized tumor immunotherapy

Environmental “superbugs” in our rivers and soils: new one health review warns of growing antimicrobial resistance crisis

Triple threat in greenhouse farming: how heavy metals, microplastics, and antibiotic resistance genes unite to challenge sustainable food production

Earthworms turn manure into a powerful tool against antibiotic resistance

AI turns water into an early warning network for hidden biological pollutants

Hidden hotspots on “green” plastics: biodegradable and conventional plastics shape very different antibiotic resistance risks in river microbiomes

Engineered biochar enzyme system clears toxic phenolic acids and restores pepper seed germination in continuous cropping soils

Retail therapy fail? Online shopping linked to stress, says study

How well-meaning allies can increase stress for marginalized people

Commercially viable biomanufacturing: designer yeast turns sugar into lucrative chemical 3-HP

Control valve discovered in gut’s plumbing system

George Mason University leads phase 2 clinical trial for pill to help maintain weight loss after GLP-1s

Hop to it: research from Shedd Aquarium tracks conch movement to set new conservation guidance

Weight loss drugs and bariatric surgery improve the body’s fat ‘balance:’ study

The Age of Fishes began with mass death

TB harnesses part of immune defense system to cause infection

Important new source of oxidation in the atmosphere found

A tug-of-war explains a decades-old question about how bacteria swim

Strengthened immune defense against cancer

Engineering the development of the pancreas

The Journal of Nuclear Medicine ahead-of-print tip sheet: Jan. 9, 2026

Mount Sinai researchers help create largest immune cell atlas of bone marrow in multiple myeloma patients

Why it is so hard to get started on an unpleasant task: Scientists identify a “motivation brake”

Body composition changes after bariatric surgery or treatment with GLP-1 receptor agonists

[Press-News.org] Study finds Dense Breast Notification legislation has not met all desired goals