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Assessment of maternal, neonatal cord blood SARS-CoV-2 antibodies, placental transfer ratios

2021-01-29
(Press-News.org) What The Study Did: 
Maternally derived antibodies are a key element of neonatal immunity. This study examined the association between maternal and neonatal SARS-CoV-2-specific antibody concentrations because understanding the dynamics of maternal antibody responses to SARS-CoV-2 infection during pregnancy and subsequent transplacental antibody transfer can inform neonatal management as well as maternal vaccination strategies.

Authors: 
Scott E. Hensley, Ph.D., of the University of Pennsylvania in Philadelphia, and Karen M. Puopolo, M.D., Ph.D., of the Children's Hospital of Philadelphia, are the corresponding authors.

To access the embargoed study:
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(doi:10.1001/jamapediatrics.2021.0038)

Editor's Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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[Press-News.org] Assessment of maternal, neonatal cord blood SARS-CoV-2 antibodies, placental transfer ratios