New study reports activated B. infantis EVC001 improves health outcomes in preterm infants

A pair of UCR studies reveal that living with a romantic partner helps people feel more socially connected during COVID-19. But no other pandemic-era social dynamic carries notable benefits, the researchers found: not your kids, not kibitzing with your bestie on Facetime, and not your adorable-adoring pets. "Research prior to the pandemic has long shown that partners are one of the strongest predictors of social connection and well-being," said UCR researcher Karynna Okabe-Miyamoto, lead co-author of the study, published recently in the journal Plos One. "And our research during the current COVID-19 pandemic has shown the same. Living with a partner uniquely buffered declines in social ...

Findings from a new Geisel-led study, published in the Journal of General Internal Medicine, reveal that there is substantial variation across different regions of the country in the intensity of fracture-associated drug (FAD) use among long-term care facility residents, and that areas with greater use of these prescription drugs experience higher hip fracture rates. In recent decades, the use of prescription medications has increased dramatically in the U.S. due to factors such as improvements in the ability to detect disease, expanding treatment options, and an aging population. For many Americans over age 65, these medications provide an effective means of managing disease and improving quality of life and longevity. However, many commonly prescribed drugs--such ...

DALLAS, Feb. 15, 2021 -- Understanding the sex differences in cardiovascular disease presentation and outcomes remains a major research priority demonstrated by the record number of submissions for this year's Go Red for Women® special issue of the American Heart Association's flagship journal Circulation, published online today. Circulation editors said more than 100 manuscripts were submitted this year, the most ever in the five years in which the current editorial board has published the special issue. "Undeniably, cardiovascular disease remains the number one killer of women around the world, taking the lives of 1 in 3 women. Even one life lost is too many, because we know much of heart disease and stroke is preventable and treatable," said Circulation Editor-in-Chief ...

Ithaca, N.Y. - At a glacier near the South Pole, earth scientists have found evidence of a quiet, slow-motion fault slip that triggers strong, fast-slip earthquakes many miles away, according to Cornell University research published in Science Advances. During an earthquake, a fast slip happens when energy builds up underground and is released quickly along a fault. Blocks of earth rapidly slide against one another. However, at an Antarctic glacier called Whillans Ice Plain, the earth scientists show that "slow slips" precede dozens of large magnitude 7 earthquakes. "We found that there is almost always a precursory 'slow slip' before an earthquake," ...

WHAT Gliomas are common brain tumors that comprise about one third of all cancers of the nervous system. In a study funded by the National Institutes of Health (NIH), researchers tested a novel combination treatment approach on mice with tumors with characteristics similar to human astrocytomas--a type of slow-growing glioma--and found tumor regression in 60 percent of the mice treated. These encouraging results, published in the Journal of Clinical Investigation, could be the first step toward developing a treatment for this type of brain cancer. Led by senior authors Maria Castro, Ph.D. and Pedro Lowenstein, M.D., Ph.D. along with a team of researchers at the University of Michigan Rogel Cancer Centerb in Ann Arbor specifically ...

High levels of public support for strict measures to control COVID-19 during the first wave of the pandemic did not reflect high levels of public trust in the UK government's honesty, transparency or motives, suggests a new study published in PLOS One. The 'mixed-methods' project, a collaboration between the London School of Hygiene & Tropical Medicine (LSHTM) and University College London (UCL), involved collecting data from more than 9,000 adults living in the UK using an online survey. It found that during the first wave of COVID-19 (April 2020) 95% of participants were in support of the government having powers to enforce behaviour change. However, only around half (52%) thought that the government was actually doing a good job of controlling COVID-19. Even fewer (36%) thought ...

New research has found that a group of genes that reduces the risk of developing severe COVID-19 by around 20% is inherited from Neanderthals These genes, located on chromosome 12, code for enzymes that play a vital role in helping cells destroy the genomes of invading viruses The study suggests that enzymes produced by the Neanderthal variant of these genes are more efficient which helps protect against severe COVID-19 This genetic variant was passed to humans around 60,000 years ago via interbreeding between modern humans and Neanderthals The genetic variant has increased in frequency over the last millennium and is now found ...

Researchers from Skoltech and their colleagues have demonstrated that nanoengineered biodegradable microcapsules can guide the development of hippocampal neurons in an in vitro experiment. The microcapsules deliver nerve growth factor, a peptide necessary for neuron growth. The paper describing this work was published in the journal Pharmaceutics. Many neurodegenerative conditions that can lead to severe disorders are associated with depleted levels of growth factors in the brain - neuropeptides that help neurons grow, proliferate and survive. Some clinical studies of Alzheimer's and Parkinson's diseases have shown that delivering these growth factors to specific degenerating neurons can have a therapeutic effect. ...

Scientists from the National Renewable Energy Laboratory (NREL) have developed a simple way to better evaluate the potential of novel materials to store or release heat on demand in your home, office, or other building in a way that more efficiently manages the building's energy use. Their work, featured in Nature Energy, proposes a new design method that could make the process of heating and cooling buildings more manageable, less expensive, more efficient, and better prepared to flexibly manage power from renewable energy sources that do not always deliver ...

Last year, researchers at Karolinska Institutet in Sweden and the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany showed that a major genetic risk factor for severe COVID-19 is inherited from Neandertals. Now the same researchers show, in a study published in PNAS, that Neandertals also contributed a protective variant. Half of all people outside Africa carry a Neandertal gene variant that reduces the risk of needing intensive care for COVID-19 by 20 percent. Some people become seriously ill when infected with SARS-CoV-2 while others get only mild or no symptoms. In addition to ...