PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Curbing COVID-19 on campuses nationwide

First study documenting public university testing outlines strategy decreasing cases by 154%

2021-03-23
(Press-News.org) While COVID-19 cases may be on the decline, the virus is still prevalent nationwide, and higher education institutions need to prepare for a successful 2021 academic year. New research from Clemson University in The Lancet Child & Adolescent Health, one of the world's premier peer-reviewed general medical journals, indicates how surveillance-based informative testing (SBIT) mitigates the spread of COVID-19 on campus, paving the way for other institutions, even those without the infrastructure or funding for mass-scale testing.

SBIT was implemented during the first two weeks of the Fall semester at Clemson. According to the study, random surveillance testing to identify outbreaks in residence halls and with targeted follow-up testing was twice as likely to detect a positive case than random testing models. In the absence of SBIT, transmission models developed by the research team show COVID cases would have increased by 154 percent.

"By focusing on residential hotspots, our SBIT strategy identified and contained outbreaks throughout campus. This strategy made efficient use of our resources, detecting positive cases at twice the rate of simple random testing," said Lior Rennert, assistant professor with the College of Behavioral, Social and Health Sciences.

The study is the first to document the implementation, results and relative effectiveness in detecting and containing COVID-19 outbreaks and mitigating university campuses' spread. For most universities, voluntary testing was implemented, leaving many cases undetected and contributing to an increase of COVID on campuses and in their surrounding communities.

The surveillance-based informative testing was spearheaded by Clemson's public health team. The authors of the manuscript are Lior Rennert, Christopher McMahan, Corey Kalbaugh, Yuan Yang, Brandon Lumsden, Delphine Dean, Lesslie Pekarek and Christopher Colenda, and are the first Clemson team to publish in a Lancet family journal.

Clemson's commitment to COVID-19 safety

The study's research team played an integral role in the University's ability to bring students back to campus in Fall 2020. Towards the tail end of the semester, there was a precipitous decline in student cases, despite significant increases in the case counts in surrounding communities. The declines were due in large part to the public health strategies implemented. At the pinnacle of these strategies was an aggressive plan to test as many students and employees as often as possible. By identifying active cases, the University was able to mitigate the virus's community spread, thus reducing risk to students, faculty, and the larger community.

What Clemson faced was not unique - and it was not the only campus with a high number of reported cases. The difference? Clemson implemented a robust and repetitive testing strategy for students and faculty regardless of symptoms or exposure. In doing so, positive cases were identified and removed from the population, thus limiting the virus's spread both on-campus and in surrounding communities through isolation and quarantine procedures.

Clemson's public health strategies were derived through data-driven means. Over the summer, the University's public health team designed and built models demonstrating pre-semester testing would reduce the spread and minimize peak cases during the semester. Acting on these findings, the University mandated all students and faculty be tested before returning to face-to-face instruction. As a part of these efforts, nearly 3,000 COVID-19 cases were discovered, preventing the return of nearly 3,000 infected students and faculty, who would have unknowingly spread the virus to others - infectivity is thought to be two to four people per confirmed case.

As in-person instruction began, the University also began randomly testing 5 percent of the student body weekly. These surveillance efforts allowed for the identification of "hotspots" in both the on- and off-campus student body. Testing was then redirected to these hotspots. This combination of testing drove the COVID prevalence to below 1 percent.

Since the initial testing efforts, Clemson's positive rate dropped weekly - as did the population using isolation and quarantine accommodations. While most of the credit should rightfully lie with students' responsible behavior, the University's public health strategies undoubtedly contributed to the decreasing case count. Beginning October 2020, the public health team implemented a weekly testing regime, keeping disease prevalence down ever since.

INFORMATION:



ELSE PRESS RELEASES FROM THIS DATE:

BMI1, a promising gene to protect against Alzheimer's disease

2021-03-23
Another step towards understanding Alzheimer's disease has been taken at the Maisonneuve-Rosemont Hospital Research Centre. Molecular biologist Gilbert Bernier, and professor of neurosciences at Université de Montréal, has discovered a new function for the BMI1 gene, which is known to inhibit brain aging. The results of his work have just been published in Nature Communications. In his laboratory, Bernier was able to establish that BMI1 was required to prevent the DNA of neurons from disorganizing in a particular way called G4 structures. This phenomenon occurs in the brains of people with Alzheimer's disease, but not in healthy elderly ...

Neutrons reveal unpredicted binding between SARS-CoV-2, hepatitis C antiviral drug

Neutrons reveal unpredicted binding between SARS-CoV-2, hepatitis C antiviral drug
2021-03-23
Scientists have found new, unexpected behaviors when SARS-CoV-2 - the virus that causes COVID-19 - encounters drugs known as inhibitors, which bind to certain components of the virus and block its ability to reproduce. Published in the Journal of Medicinal Chemistry, the research provides key insights for advancing drug design and drug repurposing efforts to treat COVID-19. Researchers at the Department of Energy's Oak Ridge National Laboratory used neutron scattering to investigate interactions between telaprevir, a drug used to treat hepatitis C viral infection, and the SARS-CoV-2 main protease, the enzyme responsible for enabling the virus to reproduce. They ...

Researchers hunt for drugs that keep HIV latent

2021-03-23
When the human immunodeficiency virus infects cells, it can either exploit the cells to start making more copies of itself or remain dormant--a phenomenon called latency. Keeping these reservoirs latent is a challenge. A new paper, published in the Proceedings of the National Academy of Sciences, has found a way to look for chemicals that can keep the virus suppressed into its dormant state. "The current drug treatments block healthy cells from becoming infected by the virus," said Yiyang Lu, a PhD student in the Dar lab at the University of Illinois Urbana-Champaign. "The latent reservoir poses a bigger problem because it can start producing the virus at any time. Consequently, patients have to remain on antiretroviral therapy all their lives to prevent ...

study: Precautions used to prevent COVID-19 decreased common respiratory illness rates

2021-03-23
Boston - Wearing masks and physical distancing - two key infection prevention strategies implemented to stop the spread of COVID-19 - may have led to the dramatic decrease in rates of common respiratory viral infections, such as influenza. A study led by researchers at Boston Medical Center (BMC) showed an approximately 80 percent reduction in cases of influenza and other common viral respiratory infections when compared to similar time periods in previous years, before wearing masks, physical distancing, and school closures were implemented to help stop the spread of COVID-19. Published online in Open Forum Infectious ...

Global health care worker burnout is high and 'unsustainable'

2021-03-23
SAN ANTONIO (March 23, 2021) -- More than half of all health care workers worldwide are experiencing burnout that, if not addressed, could cause many to leave their fields in favor of less-stressful occupations or choose early retirement. And the COVID-19 pandemic has only made it worse. That's the warning of a surgeon from The University of Texas Health Science Center at San Antonio in a letter and a call for global action published March 22 in the Lancet journal EClinicalMedicine. "A recent survey done in Medscape of nearly 7,500 physicians globally showed that burnout has reached a very high rate," said END ...

Deactivating cancer cell gene boosts immunotherapy for head and neck cancers

2021-03-23
By targeting an enzyme that plays a key role in head and neck cancer cells, researchers from the UCLA School of Dentistry were able to significantly slow the growth and spread of tumors in mice and enhance the effectiveness of an immunotherapy to which these types of cancers often become resistant. Their findings, END ...

Arsenal used by parasite to affect cellular defense and enhance leishmaniasis is revealed

Arsenal used by parasite to affect cellular defense and enhance leishmaniasis is revealed
2021-03-23
Researchers have succeeded in revealing the arsenal used by protozoans of the genus Leishmania in human cells to make leishmaniasis more severe, especially in cases of the mucocutaneous variety of the disease, which can cause deformations in patients. The discovery points the way to a search for novel treatments for the disease as well as casting light on a key mechanism involved in other diseases. The mechanism involves Leishmania, macrophages and a virus that lives endosymbiotically in the parasite and is known as the Leishmania RNA virus (LRV). According to a study published in the journal iScience, the parasite inhibits activation of caspase-11 via LRV-induced autophagy. Caspases are a family of enzymes that ...

Pilot study finds evidence of bartonella infection in schizophrenia patients

2021-03-23
A pilot study from North Carolina State University and the University of North Carolina at Chapel Hill has found evidence of Bartonella infection in the blood of people with schizophrenia and schizoaffective disorder. "Researchers have been looking at the connection between bacterial infection and neuropsychiatric disease for some time," says Dr. Erin Lashnits, a former veterinary internist at NC State, current faculty member at the University of Wisconsin and first author of the study. "Specifically, there has been research suggesting that cat ownership is associated with schizophrenia ...

Social context affects gendered views of STEM subjects in England and Japan

Social context affects gendered views of STEM subjects in England and Japan
2021-03-23
Concern over attractiveness to the opposite sex affects the masculine image of physics and mathematics only in England, while having a negative view of intellectual women is correlated with a masculine image of mathematics as a field only in Japan, according to a survey conducted in the two countries by a Japanese research group. This comparative study shows that programs to increase women's representation in these fields must take into account each country's social context surrounding gender roles. Why do so few women choose to study and work in STEM (science, technology, ...

OCD among new mothers more prevalent than previously thought

2021-03-23
Obsessive compulsive disorder (OCD) among those who have recently given birth is more common than previously thought, and much of this can be attributed to thoughts of harm related to the baby, new UBC research has found. The researchers also learned that OCD can go undetected when new parents aren't asked specifically about infant-related harm. OCD is an anxiety-related condition characterized by the recurrence of unwanted, intrusive and distressing thoughts. If left untreated, it can interfere with parenting, relationships and daily living. The study estimates that eight per cent of postpartum women report symptoms ...

LAST 30 PRESS RELEASES:

Understanding bias and discrimination in AI: Why sociolinguistics holds the key to better Large Language Models and a fairer world 

Safe and energy-efficient quasi-solid battery for electric vehicles and devices

Financial incentives found to help people quit smoking, including during pregnancy

Rewards and financial incentives successfully help people to give up smoking

HKU ecologists reveal key genetic insights for the conservation of iconic cockatoo species

New perspective highlights urgent need for US physician strike regulations

An eye-opening year of extreme weather and climate

Scientists engineer substrates hostile to bacteria but friendly to cells

New tablet shows promise for the control and elimination of intestinal worms

Project to redesign clinical trials for neurologic conditions for underserved populations funded with $2.9M grant to UTHealth Houston

Depression – discovering faster which treatment will work best for which individual

Breakthrough study reveals unexpected cause of winter ozone pollution

nTIDE January 2025 Jobs Report: Encouraging signs in disability employment: A slow but positive trajectory

Generative AI: Uncovering its environmental and social costs

Lower access to air conditioning may increase need for emergency care for wildfire smoke exposure

Dangerous bacterial biofilms have a natural enemy

Food study launched examining bone health of women 60 years and older

CDC awards $1.25M to engineers retooling mine production and safety

Using AI to uncover hospital patients’ long COVID care needs

$1.9M NIH grant will allow researchers to explore how copper kills bacteria

New fossil discovery sheds light on the early evolution of animal nervous systems

A battle of rafts: How molecular dynamics in CAR T cells explain their cancer-killing behavior

Study shows how plant roots access deeper soils in search of water

Study reveals cost differences between Medicare Advantage and traditional Medicare patients in cancer drugs

‘What is that?’ UCalgary scientists explain white patch that appears near northern lights

How many children use Tik Tok against the rules? Most, study finds

Scientists find out why aphasia patients lose the ability to talk about the past and future

Tickling the nerves: Why crime content is popular

Intelligent fight: AI enhances cervical cancer detection

Breakthrough study reveals the secrets behind cordierite’s anomalous thermal expansion

[Press-News.org] Curbing COVID-19 on campuses nationwide
First study documenting public university testing outlines strategy decreasing cases by 154%