SARS-CoV-2 positivity in asymptomatic-screened dental patients
2021-03-29
(Press-News.org) Alexandria, Va., USA -- Asymptomatic carriage of SARS-CoV-2 is a potentially significant source of transmission, yet remains relatively poorly understood. The study "SARS-CoV-2 Positivity in Asymptomatic-screened Dental Patients" published in the Journal of Dental Research (JDR), investigated SARS-CoV-2 infection in asymptomatic dental patients to inform community surveillance and improve understanding of risks in the dental setting.
Thirty-one dental care centers across Scotland invited asymptomatic screened patients over the age of five to participate. During the patient visit, trained dental teams took a combined oropharyngeal and nasal swab sample using standardized Viral Transport Medium containing test kits. Over a 13-week period, 4,032 patients were tested and of these 22 (0.5%; 95%CI 0.5%, 0.8%) tested positive for SARS-CoV-2. The positivity rate increased over the period, commensurate with uptick in community prevalence identified across all national testing monitoring data streams. The COVID-19 positivity rate in this patient group reflected the underlying prevalence in the community at the time.
This surveillance program had several advantages including using trained dental teams for the collection of high quality and complete data and samples. Moreover, there was no need for the clinical teams to use additional personal protective equipment as they were already wearing it to provide dental care and the patients could receive care despite periods of lockdown restriction.
"Enhanced community surveillance is a key pillar of the public health response to COVID-19. The results of this study demonstrate the value in, and feasibility of, developing and implementing SARS-CoV-2 surveillance testing within dental settings," said JDR Editor-in-Chief Nicholas Jakubovics, Newcastle University, England. "These data are also a salient reminder of the importance of appropriate ongoing infection prevention control and personal protective equipment vigilance."
INFORMATION:
About the Journal of Dental Research
The IADR/AADR Journal of Dental Research (JDR) is a multidisciplinary journal dedicated to the dissemination of new knowledge in all sciences relevant to dentistry and the oral cavity and associated structures in health and disease. The JDR ranks #3 in Impact Factor of 91 journals, #2 without self-citations, as well as #2 of 91 in Article Influence with a score of 1.627. The JDR's 5-year Impact Factor remained above 5 for the fifth year at 5.844 -- ranking #2 of 91 journals. With over 20,000 citations, the JDR also boasts the most citations in the "Dentistry, Oral Surgery & Medicine" category, over 3,500 citations above the 2nd ranked journal in the field.
International Association for Dental Research
The International Association for Dental Research (IADR) is a nonprofit organization with over 10,000 individual members worldwide, with a Mission to drive dental, oral and craniofacial research to advance health and well-being worldwide. To learn more, visit http://www.iadr.org. The American Association for Dental Research (AADR) is the largest Division of IADR with 3,100 members in the United States. To learn more, visit http://www.iadr.org/aadr.
ELSE PRESS RELEASES FROM THIS DATE:
2021-03-29
Laser treatment is now commonplace across various fields of medicine including dermatology, where it is commonly used to remove scars, wrinkles, and freckles. The technology, however, has a major downside: despite continued improvements, medical accidents related to laser treatment has been on the rise, with studies revealing excessively high laser energy as the major cause of such accidents.
Assistant Professor Takahiro Kono from Shibaura Institute of Technology (SIT), Japan, whose research is focused on the mechanism of heat transfer involved in the interaction of laser light with biological tissue explains, "The difficulty lies in adjusting the laser conditions for each patient ...
2021-03-29
A team of researchers led by UCL Great Ormond Street Institute of Child Health (ICH) and Great Ormond Street Hospital (GOSH) has found that metformin - a drug commonly used to treat Type 2 diabetes - can successfully reduce symptoms associated with tuberous sclerosis complex (TSC), including reduction in the frequency of seizures and the size of brain tumours.
The study, which also included teams from Royal United Hospitals Bath NHS Foundation Trust (RUH) and University Hospitals Bristol and Weston NHS Foundation Trust, recruited 51 patients with TSC who were randomly assigned a placebo or metformin for one year on a dose similar to that given for Type 2 diabetes.
TSC is a genetic disorder characterised ...
2021-03-29
In order to develop more effective drugs against a range of cancers, researchers have been investigating the molecular structure of many diseased-linked enzymes in the body. An intriguing case in point is Taspase 1, a type of enzyme known as a protease. The primary duty of proteases is to break down proteins into smaller peptide snippets or single amino acids.
Taspase 1 appears to play a vital role in a range of physiological processes, including cell metabolism, proliferation, migration and termination. The normal functioning of Taspase 1 can go awry however, leading to a range of diseases, including leukemia, colon and breast cancers, as well as glioblastoma, a particularly lethal and incurable malignancy in the brain.
Because Taspase 1 dysregulation is increasingly ...
2021-03-29
Use of vouchers and coupons offered by pharmaceutical companies to defray patients' out-of-pocket drug costs is concentrated among a small number of drugs. While these offsets significantly reduce patient costs, they are not targeted to patients who most need the price reduction, according to a study from researchers at the Johns Hopkins Bloomberg School of Public Health.
The researchers, in what is thought to be the largest study of its kind to date, analyzed tens of millions of pharmacy transactions by more than 600,000 people in the U.S. during 2017-19, in order to get a better sense of how vouchers and other point-of-sale copayment "offsets" are used. These coupons and vouchers come in many forms--some are offered online directly to customers, others by pharmacy ...
2021-03-29
When you bump into someone in the workplace or at your local coffee shop, you might call that an "encounter." That's the scientific term for it, too. As part of urgent efforts to fight COVID-19, a science is rapidly developing for measuring the number of encounters and the different levels of interaction in a group.
At the National Institute of Standards and Technology (NIST), researchers are applying that science to a concept they have created called "encounter metrics." They have developed an encrypted method that can be applied to a device such as your phone to help with the ultimate goal of slowing down or preventing future pandemics. The method is also applicable to the COVID-19 pandemic.
Their research ...
2021-03-29
A drop of food coloring slowly spreading in a glass of water is driven by a process known as diffusion. While the mathematics of diffusion have been known for many years, how this process works in living organisms is not as well understood.
Now, a study published in Nature Communications provides new insights on the process of diffusion in complex systems. The result of a collaboration between physicists at Penn, the University of Chile, and Heinrich Heine University Düsseldorf, this new theoretical framework has broad implications for active surfaces, such as ones found in biofilms, active coatings, and even mechanisms for pathogen clearance.
Diffusion is described ...
2021-03-29
BUFFALO, N.Y. - Bullying at boarding schools has a negative impact on students' emotional health, but for male students, having a school staff member to rely on for support may mute the harmful effects of bullying, according to a new University at Buffalo study. Support networks did not have the same effect for female students, the researchers say.
The study, recently published in School Psychology Review, is one of few to examine the impact of bullying at boarding schools, which provide a unique environment where most students live on school grounds, away from their families. It is also one of the first studies to observe the effects ...
2021-03-29
Climate labels informing us of a meat product's carbon footprint cause many people to opt for climate-friendlier alternatives. This applies to people who are curious about a product's carbon footprint, as well as to those who actively avoid wanting to know more. The finding is published in a new study from, among others, the University of Copenhagen. As such, climate labeling food products can be a good way of reducing our climate footprint. But according to the researcher behind the study, labels must be obligatory for them to be effective.
Certain situations exist where we humans strategically avoid greater knowledge and more information - a phenomenon known as "active information avoidance". ...
2021-03-29
The unicellular green alga Chlamydomonas reinhardtii has already given research a massive boost: One of its light sensors, channelrhodopsin-2, founded the success of optogenetics about 20 years ago.
In this technology, the alga's light sensor is incorporated into cells or small living organisms such as threadworms. Afterwards, certain physiological processes can be triggered or stopped by light. This has already led to several new scientific findings, for example on the function of nerve cells.
Now the green alga Chlamydomonas is once again setting an accent. Once again, it is its light sensors, ...
2021-03-29
High-speed atomic force microscopy (HS-AFM) is an imaging technique that can be used for visualizing biological processes, for example the activity of proteins. Nowadays, typical HS-AFM frame rates are as high as 12 frames per second. In order to improve the capabilities of the method, so that it can be applied to an ever expanding range of biological samples, better video rates are needed, though. Moreover, faster recording times imply less interaction between the sample and the probe -- a tip scanning the sample's surface -- making the imaging ...
LAST 30 PRESS RELEASES:
[Press-News.org] SARS-CoV-2 positivity in asymptomatic-screened dental patients