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U of A team identifies protein that blocks body's ability to clear bad cholesterol

Researchers are now looking to develop a drug that will boost existing statin drugs to prevent heart disease

U of A team identifies protein that blocks body's ability to clear bad cholesterol
2021-04-01
(Press-News.org) A team of researchers at the University of Alberta has uncovered a long-sought link in the battle to control cholesterol and heart disease.

The protein that interferes with low-density lipoprotein (LDL) receptors that clear "bad" cholesterol from the blood was identified in END

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U of A team identifies protein that blocks body's ability to clear bad cholesterol

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Disrupted biochemical pathway in the brain linked to bipolar disorder

2021-04-01
MADISON - Bipolar disorder affects millions of Americans, causing dramatic swings in mood and, in some people, additional effects such as memory problems. While bipolar disorder is linked to many genes, each one making small contributions to the disease, scientists don't know just how those genes ultimately give rise to the disorder's effects. However, in new research, scientists at the University of Wisconsin-Madison have found for the first time that disruptions to a particular protein called Akt can lead to the brain changes characteristic of bipolar disorder. The results offer a foundation for research into treating the often-overlooked cognitive impairments of bipolar disorder, ...

NASA OSIRIS-REx's final asteroid observation run

NASA OSIRIS-RExs final asteroid observation run
2021-04-01
NASA's OSIRIS-REx mission is on the brink of discovering the extent of the mess it made on asteroid Bennu's surface during last fall's sample collection event. On Apr. 7, the OSIRIS-REx spacecraft will get one last close encounter with Bennu as it performs a final flyover to capture images of the asteroid's surface. While performing the flyover, the spacecraft will observe Bennu from a distance of about 2.3 miles (3.7 km) - the closest it's been since the Touch-and-Go Sample Collection event on Oct. 20, 2020. The OSIRIS-REx team decided to add this last flyover after Bennu's surface was significantly disturbed by the sample collection event. During touchdown, the spacecraft's ...

BrainGate: First human use of high-bandwidth wireless brain-computer interface

BrainGate: First human use of high-bandwidth wireless brain-computer interface
2021-04-01
PROVIDENCE, R.I. [Brown University and Providence Veterans Affairs Medical Center] -- Brain-computer interfaces (BCIs) are an emerging assistive technology, enabling people with paralysis to type on computer screens or manipulate robotic prostheses just by thinking about moving their own bodies. For years, investigational BCIs used in clinical trials have required cables to connect the sensing array in the brain to computers that decode the signals and use them to drive external devices. Now, for the first time, BrainGate clinical trial participants with tetraplegia have demonstrated use of an intracortical wireless BCI with an external wireless transmitter. The system is capable of transmitting brain signals at single-neuron resolution and ...

Titanium dioxide stars in the first IFJ PAN research at the Cracow synchrotron

Titanium dioxide stars in the first IFJ PAN research at the Cracow synchrotron
2021-04-01
Few compounds are as important to industry and medicine today as titanium dioxide. Despite the variety and popularity of its applications, many issues related to the surface structure of materials made of this compound and the processes taking place therein remain unclear. Some of these secrets have just been revealed to scientists from the Institute of Nuclear Physics of the Polish Academy of Sciences. It was the first time they had used the SOLARIS synchrotron in their research. It is found in many chemical reactions as a catalyst, as a pigment in plastics, paints or cosmetics and in medical implants it ...

Spin-to-charge conversion achieves 95% overall qubit readout fidelity

Spin-to-charge conversion achieves 95% overall qubit readout fidelity
2021-04-01
The team led by Professor DU Jiangfeng and Professor WANG Ya from the Chinese Academy of Sciences (CAS) Key Laboratory of Microscale Magnetic Resonance of the University of Science and Technology of China put forward an innovative spin-to-charge conversion method to achieve high-fidelity readout of qubits, stepping closer towards fault-tolerant quantum computing. Quantum supremacy over classical computers has been fully exhibited in some specific problems, yet the next milestone, fault-tolerant quantum computing, still requires the accumulated logic gate error and the spin readout fidelity to exceed the fault-tolerant threshold. DU's team has resolved the first requirement in the nitrogen-vacancy (NV) center system ...

Pollen season in Switzerland earlier and more intense due to climate change

2021-04-01
Pollen from trees, grasses and weeds are causing seasonal allergies for approximately one fifth of the Swiss population every year. A study now found that due to climate change, the pollen season has shifted substantially over the past 30 years in onset, duration and intensity. "For at least four allergenic species, the tree pollen season now starts earlier than 30 years ago - sometimes even before January," said Marloes Eeftens, Principal Investigator and Group Leader at Swiss TPH. "The duration and intensity of the pollen season have also increased for several species, meaning that allergic people not only suffer for a longer period of time but also react stronger to these higher concentrations." The researchers analysed pollen data from 1990 ...

Low risk of researchers passing coronavirus to North American bats

Low risk of researchers passing coronavirus to North American bats
2021-04-01
The risk is low that scientists could pass coronavirus to North American bats during winter research, according to a new study led by the U.S. Geological Survey. Scientists find the overall risk to be 1 in 1,000 if no protective measures are taken, and the risk falls lower, to 1 in 3,333 or less, with proper use of personal protective equipment or if scientists test negative for COVID-19 before beginning research. The research specifically looked at the potential transmission of SARS-CoV-2, which is the type of coronavirus that causes COVID-19, from people to bats. Scientists did not examine potential ...

Search for strange Skyrmion phenomenon fails but finds stranger magnetic beaded necklace

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Evaluating HPV self-sampling

2021-04-01
A study led by Queen Mary University of London researchers has compared the performance and acceptability of a urine test and four different vaginal self-sampling collection devices to detect high risk Human Papilloma Virus (HPV). Corresponding author Professor Jack Cuzick from Queen Mary University of London said: "Uptake of cervical screening has been declining in the UK in recent years, and self-sampling is an attractive alternative to clinician collected samples, initially in non-attenders but potentially for all women as the primary option. "Cost and simplicity of use are important factors, and in low- and middle-income countries self-sampling may prove to be the only practical cost-effective ...

2D materials for conducting hole currents from grain boundaries in perovskite solar cells

2D materials for conducting hole currents from grain boundaries in perovskite solar cells
2021-04-01
Grain boundaries (GBs) in PSCs have been found to be detrimental to the photovoltaic performance of the devices. Numerous papers reported that the defects in perovskite GBs should be passivated by suitable materials, such as quaternary ammonium halide, fullerene derivatives and CH3NH3I, to alleviate carrier recombination and consequently improve the device performance. In a new paper published in Light: Science & Applications, a team of scientists, led by Professor Feng Yan from Department of Applied Physics, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, and co-workers have developed a novel method to overcome the drawback of perovskite GBs without ...

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[Press-News.org] U of A team identifies protein that blocks body's ability to clear bad cholesterol
Researchers are now looking to develop a drug that will boost existing statin drugs to prevent heart disease