(Press-News.org) Annually, more than 350,000 children in the world are affected by pediatric cancer. Radiation has improved outcomes dramatically, but the damage caused to healthy tissue can affect the long-term health of a child. While clinicians and radiation specialists design treatments using the most up-to-date information available, there hasn't been a single guiding source of data to make evidence-based decisions that are specific for children. Now, a volunteer international research collaboration is working toward providing evidence-based guidelines for radiation therapy dosing for children. Results from this effort will help in minimizing side effects while continuing to provide effective radiation therapy.
An introduction to PENTEC--or Pediatric Normal Tissue Effects in the Clinic--was END
PENTEC: World experts team up to improve outcomes for children after radiation therapy
More than 150 specialists worldwide provide evidence-based guidance to reduce long-term effects of radiation therapy in children
2021-05-12
ELSE PRESS RELEASES FROM THIS DATE:
New ebolavirus vaccine design seeks to drive stronger antibody defense
2021-05-12
LA JOLLA, CA--Scientists at Scripps Research have unveiled a new Ebola virus vaccine design, which they say has several advantages over standard vaccine approaches for Ebola and related viruses that continue to threaten global health.
In the new design, described in a paper in Nature Communications, copies of the Ebola virus outer spike protein, known as the glycoprotein, are tethered to the surface of a spherical carrier particle. The resulting structure resembles the spherical appearance of common RNA viruses that infect humans--and is starkly different from the snake-like shape of the Ebola virus.
The scientists say the design is intended to stimulate a better protective immune response than standard vaccine approaches, ...
Symbiotic bacteria in root cells may be key to producing better crops, Rutgers study finds
2021-05-12
New Brunswick, N.J. (May 12, 2021) - A Rutgers study finds that symbiotic bacteria that colonize root cells may be managed to produce hardier crops that need less fertilizer.
The study appears in the journal Microorganisms.
Bacteria stimulate root hair growth in all plants that form root hairs, so the researchers examined the chemical interactions between bacteria inside root cells and the root cell.
They found that bacteria are carried in seeds and absorbed from soils, then taken into root cells where the bacteria produce ethylene, a plant growth hormone that ...
Stimulating environments boost the brain; now scientists have found the genes responsible
2021-05-12
Environmental enrichment -- with infrastructure, unfamiliar odors and tastes, and toys and puzzles -- is often used in zoos, laboratories, and farms to stimulate animals and increase their wellbeing. Stimulating environments are better for mental health and cognition because they boost the growth and function of neurons and their connections, the glia cells that support and feed neurons, and blood vessels within the brain. But what are the deeper molecular mechanisms that first set in motion these large changes in neurophysiology? That's the subject of a recent study in END ...
Autologous adipose injection for shoulder pain in wheelchair users with spinal cord injury
2021-05-12
East Hanover, NJ. May 12, 2021. A team of specialists in regenerative rehabilitation conducted a successful pilot study investigating micro-fragmented adipose tissue (MFAT) injection for rotator cuff disease in wheelchair users with spinal cord injury. They demonstrated that MFAT injection has lasting pain-relief effects. The article, "A pilot study to evaluate micro-fragmented adipose tissue injection under ultrasound guidance for the treatment of refractory rotator cuff disease in wheelchair users with spinal cord injury," (doi: 10.1080/10790268.2021.1903140) was published ahead of print on April 8, 2021, by the Journal ...
The triple threat of coronavirus
2021-05-12
Severe symptoms of COVID-19, leading often to death, are thought to result from the patient's own acute immune response rather than from damage inflicted directly by the virus. Immense research efforts are therefore invested in figuring out how the virus manages to mount an effective invasion while throwing the immune system off course. A new study, published today in Nature, reveals a multipronged strategy that the virus employs to ensure its quick and efficient replication, while avoiding detection by the immune system. The joint labor of the research groups of Dr. Noam Stern-Ginossar at the Weizmann Institute of Science and Dr. Nir Paran and Dr. Tomer ...
Only 17 percent of free-flowing rivers are protected, new research shows
2021-05-12
New science about the fate of freshwater ecosystems released today by the journal Sustainability finds that only 17 percent of rivers globally are both free-flowing and within protected areas, leaving many of these highly-threatened systems¬--and the species that rely on them --at risk.
"Populations of freshwater species have already declined by 84 percent on average since 1970, with degradation of rivers a leading cause of this decline. As a critical food source for hundreds of millions of people, we need to reverse this trend," said Ian Harrison, freshwater specialist at Conservation International, adjunct professor ...
Obese girls face heightened risk of cardiovascular disease in adulthood
2021-05-12
By Karina Ninni | Agência FAPESP – A study of 92 adolescents conducted in Brazil suggests girls are more likely than boys to develop metabolic alterations associated with obesity, such as high blood pressure and excessive blood levels of cholesterol and triglycerides (dyslipidemia).
The study was conducted with FAPESP’s support by scientists affiliated with the University of São Paulo’s Biomedical Sciences Institute (ICB-USP) and the Medical School of Santa Casa de Misericórdia de São Paulo (FCM-SCMSP). The findings are reported in an article in the journal Frontiers in Nutrition.
According to the authors, the obese girls displayed a pattern of lipid profile alterations not seen in girls without obesity and a higher propensity to ...
Asian scientists grapple with belonging
2021-05-12
Asian students and faculty have long been a cornerstone of science in the U.S., drawn by the promise of collaboration and cutting-edge research. However, the Asian community is facing increased racist attacks and scrutiny from the government. A cover story in Chemical & Engineering News, the weekly newsmagazine of the American Chemical Society, explores how Asian scientists are reassessing their futures in the U.S.
In the wake of the COVID-19 pandemic, racist attacks against the Asian community in the U.S. have increased notably, with nearly 4,000 incidents reported between March 2020 and February 2021. Some attribute this to former President Donald Trump's rhetoric about the pandemic originating in China, writes Senior Editor Andrea Widener. ...
Mutation profile of acral nevi differs from acral melanoma, Moffitt researchers say
2021-05-12
TAMPA, Fla. -- Melanocytic nevi, or moles, are nonmalignant growths that arise from pigment producing cells of the skin. They are mostly found in sun-exposed areas; however, they also can be found in sun-protected areas, such as the palms, soles of feet and nail beds, where they are known as acral nevi. While the mutation profile of nevi in sun-exposed areas is well understood, less is known about the genes that are commonly mutated in acral nevi. And while a subset of melanoma of sun-exposed skin arises in nevi, the link between nevi and melanoma in acral skin is poorly understood. In ...
Major differences in COVID patient care caused by insufficient data, misleading advice
2021-05-12
NEW YORK, NY--While there was extensive use of drug repurposing throughout the first 10 months of the COVID-19 pandemic, there was substantial heterogeneity over the types of drugs used for treatment purposes globally. Some drugs, including hydroxychloroquine, saw sharp declines in use, while adjunctive therapies grew into a more relied upon method for patient management.
In a number of cases, scientific discovery overturned misconceptions proclaimed via press conferences and social media.
The OHDSI network study "Use of repurposed and adjuvant drugs in hospital patients with covid-19: multinational network cohort study," published May 11 by The BMJ, provides a global view ...
LAST 30 PRESS RELEASES:
New West Health-Gallup survey finds incoming Trump administration faces high public skepticism over plans to lower healthcare costs
Reading signs: New method improves AI translation of sign language
Over 97 million US residents exposed to unregulated contaminants in their drinking water
New large-scale study suggests no link between common brain malignancy and hormone therapy
AI helps to identify subjective cognitive decline during the menopause transition
Machine learning assisted plasmonic absorbers
Healthy lifestyle changes shown to help low back pain
Waking up is not stressful, study finds
Texas A&M AgriLife Research aims for better control of widespread tomato spotted wilt virus
THE LANCET DIABETES & ENDOCRINOLOGY: Global Commission proposes major overhaul of obesity diagnosis, going beyond BMI to define when obesity is a disease.
Floating solar panels could support US energy goals
Long before the L.A. fires, America’s housing crisis displaced millions
Breaking barriers: Collaborative research studies binge eating disorders in older Hispanic women
UVA receives DURIP grant for cutting-edge ceramic research system
Gene editing extends lifespan in mouse model of prion disease
Putting a lid on excess cholesterol to halt bladder cancer cell growth
Genetic mutation linked to higher SARS-CoV-2 risk
UC Irvine, Columbia University researchers invent soft, bioelectronic sensor implant
Harnessing nature to defend soybean roots
Yes, college students gain holiday weight too—but in the form of muscle not fat
Beach guardians: How hidden microbes protect coastal waters in a changing climate
Rice researchers unlock new insights into tellurene, paving the way for next-gen electronics
New potential treatment for inherited blinding disease retinitis pigmentosa
Following a 2005 policy, episiotomy rates have reduced in France without an overall increase in anal sphincter injuries during labor, with more research needed to confirm the safest rate of episiotomi
Rats anticipate location of food-guarding robots when foraging
The American Association for Anatomy announces their Highest Distinctions of 2025
Diving deep into dopamine
Automatic speech recognition on par with humans in noisy conditions
PolyU researchers develop breakthrough method for self-stimulated ejection of freezing droplets, unlocking cost-effective applications in de-icing
85% of Mexican Americans with dementia unaware of diagnosis, outpacing overall rate
[Press-News.org] PENTEC: World experts team up to improve outcomes for children after radiation therapyMore than 150 specialists worldwide provide evidence-based guidance to reduce long-term effects of radiation therapy in children