Genomics-informed decisions can help save species from extinction
2021-06-04
(Press-News.org) Researchers in Lund, Copenhagen and Norwich have shown that harmful mutations present in the DNA play an important - yet neglected - role in the conservation and translocation programs of threatened species.
"Many species are threatened by extinction, both locally and globally. For example, we have lost about ten vertebrate species in Sweden in the last century. However, all these species occur elsewhere in Europe, which means that they could be reintroduced into Sweden. Our computer simulations show how we could theoretically maximize the success of such reestablishments", says Bengt Hansson, biologist at Lund University.
In a new study published in Science, the researchers investigated which individuals might be most suited for translocation to new populations. To date, conservation geneticists have opted to select the most genetically variable individuals. However, the authors argue that is important to consider what type of genetic variation is being move around. Using computer simulations, they showed that harmful mutations present in the genome of translocated individuals can cause problems in future generations. This so called "mutation load" could jeopardize the viability of the new population in the long run and eventually led to extinction.
According to Hansson and van Oosterhout, geneticist at University of East Anglia, Norwich, who led the study, the best choice is to exclude individuals with many harmful mutations, whilst at the same time, selecting individuals from multiple different source populations.
"Active translocation of animals between localities is sometimes the last option available to conservation biologists. By carefully selecting individuals based on their low mutation load, we can minimize the loss of fitness that is normally associated with inbreeding in small populations", says Bengt Hansson.
Huge advances have been made in DNA sequencing technologies, and the whole genomes of individuals can now be sequenced for relatively little costs. This opens up new possibilities to improve the conservation management of threatened species.
"For many species of mammals and birds, we now know which mutations are harmful. Similar mutations are also found in humans, so we understand what they do, and hence, we know what to look out for when analyzing the sequence data of those species. The advantage of using DNA sequencing is that we can see these mutations in the genome, even if an individual carries just a single copy of the mutant gene. This means we can select against those bad mutations even before they cause a problem. Our computer model shows that at least theoretically, this ensures the best probability for population survival. This could help conservation managers in picking the optimal individuals of a threatened species for translocation into a new habitat", says van Oosterhout.
INFORMATION:
ELSE PRESS RELEASES FROM THIS DATE:
2021-06-04
The COVID-19 pandemic forced instructors to adapt their courses for online learning. Laboratory courses were particularly difficult due to lack of access to specialized equipment for remote learners. To overcome this challenge, researchers from the University of Illinois Urbana-Champaign designed a laboratory exercise to teach students how to use micropipettes, through remote learning, using at-home kits.
Micropipettes are common--and essential--laboratory instruments and are used in several fields including molecular biology, microbiology, and biochemistry. They are used to accurately transfer very small volumes of liquid. To teach students how to use these instruments, the researchers developed kits, costing $135 per student, that were a fraction ...
2021-06-04
COLUMBUS, Ohio - New research suggests that African American families living in public housing are a "hidden population" when it comes to national suicide prevention efforts.
The study showed 11% of Black teens and young adults living in a mid-Atlantic public housing development reported that in the previous 12 months, they had made a plan to die by suicide.
The finding fits with what previous research has shown: that African American youths are the fastest-growing group engaging in suicidal behavior and dying by suicide, and have the highest suicide death rate increase among any other racial or ethnic minority group, ...
2021-06-04
How plants cope with stress factors has already been broadly researched. Yet what happens when a plant is confronted with two stressors simultaneously? A research team working with Simon Haberstroh and Prof. Dr. Christiane Werner of the Chair of Ecosystem Physiology at the Institute of Forest Sciences and Natural Resources (UNR) of the University of Freiburg is investigating this. Together with colleagues from the Forest Research Center of the School of Agriculture of the University of Lisbon in Portugal and the Institute of Meteorology and Climate Research at ...
2021-06-04
Highlights
Among adults with kidney failure undergoing hemodialysis in New York City, Black and Hispanic patients were more likely to develop symptomatic COVID-19 than White patients.
Neighborhood-level social vulnerability factors were associated with COVID-19 incidence among White patients, but these factors did not explain racial/ethnic disparities.
Washington, DC (June 1, 2021) -- In an analysis of patients on hemodialysis in New York City, there were substantial racial/ethnic disparities in COVID-19 rates that were not explained by neighborhood social vulnerability. The findings appear in an upcoming ...
2021-06-04
LOWELL, Mass. - A UMass Lowell geologist is among the researchers who have discovered a new type of manmade quasicrystal created by the first test blast of an atomic bomb.
The formation holds promise as a new material that could one day help repair bone, insulate heat or convert heat to electricity, among other uses, according to UMass Lowell Prof. G. Nelson Eby, a member of the university's Environmental, Earth and Atmospheric Sciences Department.
Eby is a member of the research team that identified the quasicrystal substance inside samples of trinitite they examined that were collected from the debris of the first atomic bomb detonated by the U.S. Army on July 16, 1945 in the New Mexico desert. Also known as atomic rock, trinitite ...
2021-06-04
New York, NY, June 3, 2021 -- A study of over 59,000 Icelandic adolescents by a team of Icelandic and North American behavioral and social scientists found that COVID-19 has had a significant, detrimental impact on adolescent mental health, especially in girls. The study is the first to investigate and document age- and gender-specific changes in adolescent mental health problems and substance use during the COVID-19 pandemic, while accounting for upward trends that were appearing before the pandemic. The findings are published in The Lancet Psychiatry.
The study found that negative mental health outcomes were disproportionately reported by girls and older adolescents (13-18-year-olds), compared to same-age peers prior to the pandemic. At the same ...
2021-06-04
A first encounter with the dengue virus typically causes very mild symptoms; however, a subsequent infection is a different story. For a small proportion of people who are reinfected, the virus can cause severe symptomatic disease, which is often life-threatening.
"The main hypothesis for some time has been that antibodies generated the first time around, instead of providing protection against disease, can actually exacerbate it," says Stylianos Bournazos, research assistant professor at Rockefeller. "But even in secondary infection, we see a wide range of symptoms--so ...
2021-06-04
As India continues to be ravaged by the pandemic, a Swansea University academic is investigating how green tea could give rise to a drug capable of tackling Covid-19.
Dr Suresh Mohankumar carried out the research with colleagues in India during his time at JSS College of Pharmacy, JSS Academy of Higher Education and Research in Ooty prior to taking up his current role at Swansea University Medical School.
He said: "Nature's oldest pharmacy has always been a treasure of potential novel drugs and we questioned if any of these compounds could assist us in battling the Covid-19 pandemic?
"We screened and sorted a library of natural compounds already know to be active against other coronaviruses using an artificial ...
2021-06-04
Hospital price transparency is intended to help inform patients about the cost of services and procedures before they receive them. Since Jan. 1, 2021, hospitals in the U.S. have been required by The Centers for Medicare and Medicaid Services (CMS) to provide pricing information online about items and services. A team of researchers from Brigham and Women's Hospital and Massachusetts Eye and Ear leveraged the newly available data to analyze price transparency and price variation for the treatment of thyroid cancer. The team found that both transparency and price varied widely, with only half of the cancer centers studied reporting disclosure ...
2021-06-04
EAST LANSING, Mich. - New research from MSU shows that an infant's gut microbiome could contain clues to help monitor and support healthy neurological development
Why do some babies react to perceived danger more than others? According to new research from Michigan State University and the University of North Carolina, Chapel Hill, part of the answer may be found in a surprising place: an infant's digestive system.
The human digestive system is home to a vast community of microorganisms known as the gut microbiome. The MSU-UNC research team discovered that the gut microbiome was different in infants with strong fear responses and infants with milder ...
LAST 30 PRESS RELEASES:
[Press-News.org] Genomics-informed decisions can help save species from extinction
