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New study underscores the role of race and poverty in COVID-19

An analysis of both inpatient and outpatient data within an integrated health system demonstrates the role of structural, societal factors in the pandemic's spread

2021-06-09
(Press-News.org) BOSTON - A new analysis by researchers at Massachusetts General Hospital (MGH) offers a novel perspective on the disproportionate impact that COVID-19 has had on people of color, low-income populations, and other structurally disadvantaged groups. Their findings, published in a research letter to the END


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The SARS-CoV-2 papain-like protease (PLpro) plays an essential role in processing viral proteins needed for replication. In addition, the enzyme can cut and inactivate some human proteins important for an immune response. Now, researchers reporting in ACS Infectious Diseases have found other targets of PLpro in the human proteome, including proteins involved in cardiovascular function, blood clotting and inflammation, suggesting a link between the inactivation of these proteins and COVID-19 symptoms. Viruses like SARS-CoV-2 make multiple proteins as one long "polyprotein." Viral enzymes called proteases recognize specific amino acid sequences in this polyprotein and cut them to release individual proteins. ...

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2021-06-09
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CHIME telescope detects more than 500 mysterious fast radio bursts in its first year of operation

2021-06-09
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[Press-News.org] New study underscores the role of race and poverty in COVID-19
An analysis of both inpatient and outpatient data within an integrated health system demonstrates the role of structural, societal factors in the pandemic's spread