Suicidal thoughts, attempts among US adolescents

Diseases that affect tubular structures in the body, such as the gastrointestinal (GI) system, vasculature and airway, present a unique challenge for delivering local treatments. Vertically oriented organs, such as the esophagus, and labyrinthine structures, such as the intestine, are difficult to coat with therapeutics, and in many cases, patients are instead prescribed systemic drugs that can have immunosuppressive effects. To improve drug delivery for diseases that affect tubular organs, like eosinophilic esophagitis and inflammatory bowel disease, ...

CAMBRIDGE, MA -- Inspired by kirigami, the Japanese art of folding and cutting paper to create three-dimensional structures, MIT engineers and their collaborators have designed a new type of stent that could be used to deliver drugs to the gastrointestinal tract, respiratory tract, or other tubular organs in the body. The stents are coated in a smooth layer of plastic etched with small "needles" that pop up when the tube is stretched, allowing the needles to penetrate tissue and deliver a payload of drug-containing microparticles. Those drugs are then released over an extended period of time after the stent is removed. This kind of localized drug delivery could make it easier ...

Like amyloid plaque, the genetic variant APOE4 has long been associated with Alzheimer's disease, but still little is known about the role the gene plays in the disease process. Now, a new study published in END ...

A non-contact laser imaging system could help doctors diagnose and treat eye diseases that cause blindness much earlier than is now possible. The new technology, developed by engineering researchers at the University of Waterloo, is designed to detect telltale signs of major blinding diseases in retinal blood and tissue that typically go unseen until it is too late. With current testing methods, diseases such as age-related macular degeneration, diabetic retinopathy and glaucoma--which have no symptoms in their early stages--are usually diagnosed only after vision is irreversibly affected. "We're optimistic that our technology, by providing functional details of the eye such as oxygen saturation and oxygen metabolism, may be able to play a critical role in early ...

PULLMAN, Wash. - Most consumers care about the technology and the ingredients used to make their microwavable dinners and other shelf ready meals, according to a new study led by Washington State University researchers. The study found that many consumers are willing to pay a premium for ready-to-eat meals with a 'clean label' showing few ingredients. They are also more willing to fork out their hard-earned cash when they know their processed foods are made with a new technology that helps limit the number of additives and preservatives commonly found in most ...

Advancements in wearable technology are reshaping the way we live, work and play, and also how healthcare is delivered and received. Wearables that have weaved their way into everyday life include smart watches and wireless earphones, while in the healthcare setting, common devices include wearable injectors, electrocardiogram (ECG) monitoring patches, listening aids, and more. A major pain point facing the use of these wearables is the issue of keeping these devices properly and conveniently powered. As the number of wearables one uses increases, the need to charge multiple ...

Neurons, nerve cells in the brain, are central players in brain function. However, a key role for glia, long considered support cells, is emerging. A research group at the University of Basel has now discovered two new types of glial cells in the brain, by unleashing adult stem cells from their quiescent state. These new types of glia may play an important role in brain plasticity and repair. The brain is malleable well into adulthood. Brain plasticity is not only due to the formation of new nerve connections. Stem cells present in the adult brain also ...

Moreover, they identified a correlation between the progression of the disease and certain corpuscles in the cell nuclei. They published their report in the journal Acta Neuropathological Communications on 13 April 2021. Aggregates seem to have a function Affecting over 50 million people, Alzheimer's disease is the most common form of dementia and primarily occurs in people over the age of 65. The pathology of the disease in the brain is mainly characterised by two factors: beta-amyloid plaques outside the nerve cells and tau proteins. The tau protein stabilises tube-like structures (microtubules) inside cells, which are relevant ...

With Oskar Aszmann and his team at the Department of Plastic, Reconstructive and Aesthetic Surgery, MedUni Vienna has long been regarded as a world leader in bionic limb reconstruction. It was only last year that the world's first fully integrated bionic arm prosthesis was developed at MedUni Vienna. This is ready-to-use and is described as "Plug and Play". Although all bionic aids have so far been used in humans, the technique known as osseointegration (direct skeletal attachment) has now been used for the very first time in a bearded vulture - the creature was given a new foot. A paper on this ground-breaking procedure has been published today (Friday) in the prestigious Journal Scientific Reports. In large birds such as vultures, the loss of limbs results in the ...

Researchers at Tohoku University have demonstrated the designability of novel magnets with magic mirror-like characteristics in organic-inorganic hybrid perovskite (OIHP)-type compounds. OIHP-type compounds, a type of material used to construct solar cells, possess exceptional optical properties and have recently attracted worldwide interest. Researchers are keen to harness their structural diversity. Although the superior optical properties of OIHPs have been mainly studied for their photoelectric characteristics, several OIHP-type compounds are known to function as magnets that transmit light. Combining the excellent optical ...