Listening to mix of sounds and silence preserves temporal sound processing in mice
Technique holds promise as non-invasive intervention for sensorineural hearing loss
(Press-News.org) Broadband sounds embedded with short pauses can maintain temporal sound processing in a mouse model of hearing loss, according to new research published in eNeuro.
Hearing loss treatments supplement auditory system function but don't repair it. However a new intervention -- playing broadband sounds during the onset of hearing loss -- may be able to prevent the damage from ever occurring. Augmented auditory environments have been able to preserve auditory processing of a wide range of sound frequencies in mice models. In a new study, Dziorny et al. modified the traditional paradigm and preserved the processing of time-related, or temporal, sound features which are vital for understanding speech.
The research team exposed mice with congenital hearing loss to traditional augmented auditory environment, and a new one with almost undetectable gaps of silence. After 12 hours of exposure per day for 20 to 22 days, the team tested the animals' response to sound in their brainstems, cochleas, and midbrains. Both interventions preserved sound processing function in all three areas compared to mice that didn't receive treatment. They also prevented hair cells from dying. But the version with gaps went even further: it maintained the ability to process temporal qualities of sounds. Augmented auditory environments show promise as non-invasive intervention to minimize the effects of congenital hearing loss.
Paper title: Rescuing Auditory Temporal Processing With a Novel Augmented Acoustic Environment in an Animal Model of Congenital Hearing Loss
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eNeuro is an online, open-access journal published by the Society for Neuroscience. Established in 2014, eNeuro publishes a wide variety of content, including research articles, short reports, reviews, commentaries and opinions.
About The Society for Neuroscience
The Society for Neuroscience is the world's largest organization of scientists and physicians devoted to understanding the brain and nervous system. The nonprofit organization, founded in 1969, now has nearly 37,000 members in more than 90 countries and over 130 chapters worldwide.
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[Press-News.org] Listening to mix of sounds and silence preserves temporal sound processing in mice
Technique holds promise as non-invasive intervention for sensorineural hearing loss