Technology that restores the sense of touch in nerves damaged as a result of injury
Cut your finger and lost your sense of touch? There's hope yet
2021-07-12
(Press-News.org) Tel Aviv University's new and groundbreaking technology inspires hope among people who have lost their sense of touch in the nerves of a limb following amputation or injury. The technology involves a tiny sensor that is implanted in the nerve of the injured limb, for example in the finger, and is connected directly to a healthy nerve. Each time the limb touches an object, the sensor is activated and conducts an electric current to the functioning nerve, which recreates the feeling of touch. The researchers emphasize that this is a tested and safe technology that is suited to the human body and could be implanted anywhere inside of it once clinical trials will be done.
The technology was developed under the leadership of a team of experts from Tel Aviv University: Dr. Ben M. Maoz, Iftach Shlomy, Shay Divald, and Dr. Yael Leichtmann-Bardoogo from the Department of Biomedical Engineering, Fleischman Faculty of Engineering, in collaboration with Keshet Tadmor from the Sagol School of Neuroscience and Dr. Amir Arami from the Sackler School of Medicine and the Microsurgery Unit in the Department of Hand Surgery at Sheba Medical Center. The study was published in the prestigious journal ACS Nano.
The researchers say that this unique project began with a meeting between the two Tel Aviv University colleagues - biomedical engineer Dr. Maoz and surgeon Dr. Arami. "We were talking about the challenges we face in our work," says Dr. Maoz, "and Dr. Arami shared with me the difficulty he experiences in treating people who have lost tactile sensation in one organ or another as a result of injury. It should be understood that this loss of sensation can result from a very wide range of injuries, from minor wounds - like someone chopping a salad and accidentally cutting himself with the knife - to very serious injuries. Even if the wound can be healed and the injured nerve can be sutured, in many cases the sense of touch remains damaged. We decided to tackle this challenge together, and find a solution that will restore tactile sensation to those who have lost it."
In recent years, the field of neural prostheses has made promising developments to improve the lives of those who have lost sensation in their limbs by implanting sensors in place of the damaged nerves. But the existing technology has a number of significant drawbacks, such as complex manufacturing and use, as well as the need for an external power source, such as a battery. Now, the researchers at Tel Aviv University have used state-of-the-art technology called a triboelectric nanogenerator (TENG) to engineer and test on animal models a tiny sensor that restores tactile sensation via an electric current that comes directly from a healthy nerve and doesn't require a complex implantation process or charging.
The researchers developed a sensor that can be implanted on a damaged nerve under the tip of the finger; the sensor connects to another nerve that functions properly and restores some of the tactile sensation to the finger. This unique development does not require an external power source such as electricity or batteries. The researchers explain that the sensor actually works on frictional force: whenever the device senses friction, it charges itself.
The device consists of two tiny plates less than half a centimeter by half a centimeter in size. When these plates come into contact with each other, they release an electric charge that is transmitted to the undamaged nerve. When the injured finger touches something, the touch releases tension corresponding to the pressure applied to the device - weak tension for a weak touch and strong tension for a strong touch - just like in a normal sense of touch.
The researchers explain that the device can be implanted anywhere in the body where tactile sensation needs to be restored, and that it actually bypasses the damaged sensory organs. Moreover, the device is made from biocompatible material that is safe for use in the human body, it does not require maintenance, the implantation is simple, and the device itself is not externally visible.
According to Dr. Maoz, after testing the new sensor in the lab (with more than half a million finger taps using the device), the researchers implanted it in the feet of the animal models. The animals walked normally, without having experienced any damage to their motor nerves, and the tests showed that the sensor allowed them to respond to sensory stimuli. "We tested our device on animal models, and the results were very encouraging," concludes Dr. Maoz. "Next, we want to test the implant on larger models, and at a later stage implant our sensors in the fingers of people who have lost the ability to sense touch. Restoring this ability can significantly improve people's functioning and quality of life, and more importantly, protect them from danger. People lacking tactile sensation cannot feel if their finger is being crushed, burned or frozen."
INFORMATION:
Dr. Maoz's laboratory:
https://www.maozlab.com/
Link to the article:
https://pubs.acs.org/doi/full/10.1021/acsnano.0c10141
[Attachments] See images for this press release:
ELSE PRESS RELEASES FROM THIS DATE:
2021-07-12
For quite some time, farmers and researchers have been focusing on how to bind carbon to soil. Doing so makes food crops more nutritious and increases yields.
However, because carbon is converted into CO2 when it enters the atmosphere, there is a significant climate benefit to capturing carbon in soil as well.
Too much carbon finds its way into the atmosphere. Should we fail to reverse this unfortunate trend, we will fail to achieve the Paris Agreement's goal of reducing greenhouse gas emissions by 40 percent by 2030, according to CONCITO, Denmark's Green Think Tank.
As such, it is important to find new ways of sequestering carbon in soil. This ...
2021-07-12
A Moon-scanning method that can automatically classify important lunar features from telescope images could significantly improve the efficiency of selecting sites for exploration.
There is more than meets the eye to picking a landing or exploration site on the Moon. The visible area of the lunar surface is larger than Russia and is pockmarked by thousands of craters and crisscrossed by canyon-like rilles. The choice of future landing and exploration sites may come down to the most promising prospective locations for construction, minerals or potential energy resources. However, scanning by eye across such a large area, looking for features perhaps a few hundred meters across, is laborious and often inaccurate, which makes it difficult ...
2021-07-12
Smoking among young teens has become an increasingly challenging and costly public healthcare issue. Despite legislation to prevent the marketing of tobacco products to children, tobacco companies have shrewdly adapted their advertising tactics to circumvent the ban and maintain their access to this impressionable--and growing--market share.
How they do it is the subject of a recent study led by Dr. Yael Bar-Zeev at Hebrew University of Jerusalem (HU)'s Braun School of Public Health and Community Medicine at HU-Hadassah Medical Center. She also serves as Chair ...
2021-07-12
Forest clearance in Southeast Asia is accelerating, leading to unprecedented increases in carbon emissions, according to new research.
The findings, revealed by a research team including University of Leeds academics, show that forests are being cut down at increasingly higher altitudes and on steeper slopes in order to make way for agricultural intensification.
As a result, more than 400 million metric tons of carbon are released into the atmosphere every year as forests are cleared in the region, with that emissions figure increasing in recent ...
2021-07-12
A Sussex team - including university mathematicians - have created a new modelling toolkit which predicts the impact of COVID-19 at a local level with unprecedented accuracy. The details are published in the International Journal of Epidemiology, and are available for other local authorities to use online, just as the UK looks as though it may head into another wave of infections.
The study used the local Sussex hospital and healthcare daily COVID-19 situation reports, including admissions, discharges, bed occupancy and deaths.
Through the pandemic, the newly-published modelling has been used by local NHS and public ...
2021-07-12
Humans can easily identify sweet-tasting foods - and with pleasure. However, many carnivorous animals lack this ability, and whether birds, descendants of meat-eating dinosaurs, can taste sweet was previously unclear. An international team of researchers led by Max Planck Institute for Ornithology including Dr Simon SIN from Research Division for Ecology and Biodiversity, The University of Hong Kong (HKU), has now shown that songbirds, a group containing over 4,000 species, can sense sweetness regardless of their primary diets. The study highlights a specific event in the songbird ancestors ...
2021-07-12
In the vicinity of black holes, space is so warped that even light rays may curve around them several times. This phenomenon may enable us to see multiple versions of the same thing. While this has been known for decades, only now do we have an exact, mathematical expression, thanks to Albert Sneppen, student at the Niels Bohr Institute. The result, which even is more useful in realistic black holes, has just been published in the journal Scientific Reports.
You have probably heard of black holes -- the marvelous lumps of gravity from which not even light can escape. You may also have heard that space itself and even time behave oddly near black holes; space is warped.
In the vicinity of a black hole, space ...
2021-07-12
The impact of El Nino on East Asian climate under a warmer climate will be dominated by the change in El Nino decaying pace, according to a new paper published by a research team based in the Institute of Atmospheric Physics, Chinese Academy of Sciences, China.
The western North Pacific anomalous anticyclone (WNPAC) is a low-level atmospheric circulation system, linking up El Nino events with East Asian -western Pacific summer climate. The WNPAC can persist from El Nino mature phase in boreal winter to the upcoming summer, bringing abundant moisture to enhance the precipitation over East Asia. How the WNPAC will change in the future concerns millions of ...
2021-07-12
July 12, New Delhi - Women who received free meals in primary school have children with improved linear growth, according to a new study by researchers at the International Food Policy Research Institute (IFPRI).
India is home to the highest number of undernourished children and the largest school feeding program in the world--the Mid-Day Meal (MDM) scheme--yet long-term program benefits on nutrition are unknown. As school feeding programs target children outside the highest-return "first 1000-days" window spanning from conception until a child's second birthday, they have not been a focal point in the global agenda to address stunting. School meals benefit education and nutrition in participants, but ...
2021-07-12
Ecologists from the Conservation Forensics Laboratory of the Research Division for Ecology and Biodiversity at the University of Hong Kong (HKU) have applied stable isotope techniques to determine whether birds in the pet trade are captive or wild-caught, a key piece of evidence required in many cases to determine whether a trade is legal or not. They have applied this technique to the yellow-crested cockatoo (Cacatua sulphurea, YCC), a critically endangered species from Indonesia/Timor-Leste with a global population of fewer than 2,500, according to the International Union for the Conservation of Nature (IUCN). Threatened by overexploitation for the pet trade, Hong Kong has a sizeable ...
LAST 30 PRESS RELEASES:
[Press-News.org] Technology that restores the sense of touch in nerves damaged as a result of injury
Cut your finger and lost your sense of touch? There's hope yet
