PRESS-NEWS.org - Press Release Distribution
PRESS RELEASES DISTRIBUTION

Impact of Covid-19 pandemic on incidence of long-term conditions in Wales

Population data linkage study using anonymised primary and secondary care health records reveals that in 2020 and 2021 fewer people in Wales were being diagnosed with long-term conditions than expected.

2023-03-13
(Press-News.org) A population data linkage study using anonymised primary and secondary care health records in Swansea University’s SAIL Databank has revealed that in 2020 and 2021, fewer people in Wales were being diagnosed with long-term conditions than expected.

Diagnosis rates increased over the two-year period but for most conditions, they still lagged behind expectations at the end of 2021 implicating a potential backlog of undiagnosed patients who are unlikely to be receiving systematic monitoring and management for their conditions.

The study was led by researchers from Population Data Science at Swansea University Medical School in partnership with the Wales Covid-19 Evidence Centre, Welsh Government, Cardiff University and PRIME Centre Wales.

Among the most affected conditions were chronic obstructive pulmonary disease (COPD) and anxiety disorders corresponding to more than 30 and 80 ‘missing’ diagnoses in a typical general practice of 10,000 patients, respectively.

Such a practice may have more than 400 missing diagnoses across the 17 conditions studied. Researchers did not find any notable differences in socio-demographic characteristics of the patients diagnosed pre- and post- pandemic such as age, sex and ethnicity.

A second phase of research will build on this work to investigate the impact of Covid on patterns of healthcare resource use for patients with long-term conditions.

The study team conducted a population data linkage study using primary and secondary care data within the Secure Anonymised Information Linkage (SAIL) Databank. They identified 2,257,992 individuals living in Wales diagnosed for the first time with any of 17 long-term conditions between Jan 1, 2000, and Dec 31, 2021.

Comparing diagnosis rates of each condition from 2020 to 2021 to forecasted expectations based on rates from 2015 to 2019, the researchers estimated the difference between the total number of expected and recorded diagnoses over the two-year period.

This research uncovers a potential backlog of undiagnosed patients with multiple long-term conditions in Wales requiring resources to tackle anticipated workload as part of Covid-19 recovery, particularly in primary care.

“This study gives us valuable insight into the wider effects the pandemic has had on people, communities and the NHS in Wales,” said Professor Kieran Walshe, Director of Health and Care Research Wales and Professor of Health Policy and Management.

“Research partnerships like this demonstrate not only the huge value of collaboration in research but also the range of benefits offered by making full use of routinely collected data. From April this year, the newly expanded Wales Evidence Centre will deliver on a wider remit, addressing key priority issues in health, public health and social care.”

Co-director of SAIL Databank, Professor Ronan Lyons added: “SAIL Databank has been an integral tool for monitoring transmission and the long-term effects of the pandemic since it first emerged. Over the last 15 years, the teams at SAIL and Population Data Science, together with others across public health bodies in Wales, have worked hard to develop our network and capabilities which has enabled us to respond swiftly and effectively to this health crisis.

“As part of this One Wales collaboration our work is far from over as we continue to monitor and assess Covid-19’s impact across Wales and ensure that we learn from this experience and further enhance our collective resolve and knowledge for future health emergencies.”

Adrian Edwards, Wales Covid-19 Evidence Centre Director, said: "This is a vital area of research in reducing gaps in health inequality in Wales. We are delighted to have been able to fund and support this research alongside our dedicated collaborating partners at the Population Data Science team, Swansea University.”

 

END


ELSE PRESS RELEASES FROM THIS DATE:

Risk of death for people with dementia increases after a hurricane exposure

2023-03-13
Previous studies of hurricanes have shown general increases in mortality but little has been known about how mortality following hurricane exposure may differ among older adults living with dementia.    Their increased risk could be due to disruption of normal routine, such as access to caregiving, changes in living environment, loss in access to medications, and change in daily routines, said study first author Sue Anne Bell, assistant professor at the U-M School of Nursing.   The analysis focused on risk for mortality among people ...

Cherenkov color imaging shows promise in enhancing radiation therapy effectiveness

Cherenkov color imaging shows promise in enhancing radiation therapy effectiveness
2023-03-13
Cherenkov imaging is a valuable cancer treatment tool that can help doctors track and monitor radiation doses received by tissues during cancer therapy in real time. This imaging technique works by detecting Cherenkov radiation, which is emitted by tissues exposed to high-energy radiation, such as X-rays or electron beams from a linear accelerator. As high-energy charged particles from the incident radiation pass through biological tissue, either as primary or secondary radiation, they interact with the electromagnetic fields of the atoms and molecules in the tissue. These soft collision-type interactions ...

Abnormal biomarkers associated with obesity are identified in very young Latino children, study finds

2023-03-13
In the United States, low-income, Latino youth are disproportionately affected by obesity with 25.8% of Latino youth aged 2-19 considered to have obesity, which is approximately two times more likely when compared to their non-Latino white counterparts. A higher level of obesity results in an increased risk of cardiometabolic diseases, which are a group of related diseases caused by an unhealthy lifestyle and/or an increased genetic predisposition. A new study by Allison McKay, RDN, department manager for the Department of Nutrition and Food Studies, identified elevated insulin, hemoglobin A1C, triglycerides, and other cardiometabolic ...

People should have right to shape marine environmental decisions

People should have right to shape marine environmental decisions
2023-03-13
Government and political institutions should do more to make citizens feel empowered within marine environment decisions and give them the right to participate, new research shows. Marine Citizenship is the term used for people who get involved in changing how humans use the ocean. It has been investigated as a potential policy tool to engage the public in marine environmental issues through a new study by the University of Exeter and the University of Bristol Law School. Despite efforts to tackle human causes such as overfishing, marine litter, microplastics, pollution, ocean acidity, global warming and climate change, there ...

New targets for CAR-T cell therapy against acute myeloid leukemia through AI-assisted analysis

2023-03-13
Unlike other forms of blood cancer, acute myeloid leukemia (AML) cannot currently be treated with CAR-T cell immunotherapy. The reason is that specific molecular targets with which certain immune cells could specifically target AML cells are lacking, which would permit the immune system to attack cancer. Two research teams of Professor Dr. Sebastian Kobold with Dr. Adrian Gottschlich from the Division of Clinical Pharmacology at LMU University Hospital Munich and Dr. Carsten Marr with Moritz Thomas from the Institute of AI for Health at Helmholtz Munich have now ...

The fat tax: Long-term, systemic antibiotic use for the treatment of adolescent acne can promote fat accumulation

The fat tax: Long-term, systemic antibiotic use for the treatment of adolescent acne can promote fat accumulation
2023-03-13
A growing body of evidence is showing that the healthy gut microbiome – a community of microorganisms that live together in the gut – influences many aspects of human growth and development, especially during adolescence. While there are many physiologic changes during this time, one of the most outward facing, and sometimes distressing, is the development of acne. Most individuals treat their acne with topical therapies; however, around 25% of adolescents require systemic antibiotics, such as minocycline, to help to alleviate symptoms and clear up the skin. These systemic antibiotic ...

Insilico Medicine brings AI-powered “ChatPandaGPT” to its target discovery platform

Insilico Medicine brings AI-powered “ChatPandaGPT”  to its target discovery platform
2023-03-13
Insilico Medicine, a clinical-stage generative artificial intelligence (AI)-powered drug discovery company, has integrated advanced AI chat functionality based on recent advances in large language models into its PandaOmics platform. The new feature, “ChatPandaGPT,” enables researchers to have natural language conversations with the platform and efficiently navigate and analyze large datasets, facilitating the discovery of potential therapeutic targets and biomarkers in a more efficient manner. Insilico Medicine is the first biotech company to implement chat functionality using large language models into its AI drug ...

Oncotarget | Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells

Oncotarget | Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells
2023-03-13
“Selective protection of normal cells may transform therapy of cancer.”  BUFFALO, NY- March 13, 2023 – A new review paper was published in Oncotarget's Volume 14 on March 11, 2023, entitled, “Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells.” Cancer therapy is limited by toxicity in normal cells and drug-resistance in cancer cells. In his latest review, Mikhail V. Blagosklonny, M.D., Ph.D., from Roswell Park Comprehensive Cancer Center discusses the theory that cancer resistance to certain therapies can be exploited ...

Agriculture needs fresh approach to tackle insect resistance to biopesticides, new analysis finds

Agriculture needs fresh approach to tackle insect resistance to biopesticides, new analysis finds
2023-03-13
Insect pests which attack crops have extraordinary powers to develop resistance to greener pesticides and a new way to manage resistance risks is needed, according to analysis by University of Stirling scientists. For more than 70 years, agriculture’s response to pesticide resistance has been to seek new pesticides in an endless race to keep up with evolving pests. Researchers now propose a new way to step off this treadmill as farmers embrace the ongoing green revolution in pest control by switching to biopesticides derived from natural organisms. The evolution of resistance to biopesticides - a crucial tool in ...

Racial health inequality in prostate cancer associated with facility-level disparities

2023-03-13
Racial minorities in the United States are less likely to receive treatment for prostate cancer and, overall, have worse survival outcomes compared to individuals who are white. Typically, patient-level and physician-level factors have been used to explain the racial and socioeconomic differences in prostate cancer disparities. However, a new study led by investigators from Brigham and Women’s Hospital, a founding member of the Mass General Brigham healthcare system, investigated the role of facilities themselves ...

LAST 30 PRESS RELEASES:

Scientists unlock secrets behind flowering of the king of fruits

Texas A&M researchers illuminate the mysteries of icy ocean worlds

Prosthetic material could help reduce infections from intravenous catheters

Can the heart heal itself? New study says it can

Microscopic discovery in cancer cells could have a big impact

Rice researchers take ‘significant leap forward’ with quantum simulation of molecular electron transfer

Breakthrough new material brings affordable, sustainable future within grasp

How everyday activities inside your home can generate energy

Inequality weakens local governance and public satisfaction, study finds

Uncovering key molecular factors behind malaria’s deadliest strain

UC Davis researchers help decode the cause of aggressive breast cancer in women of color

Researchers discovered replication hubs for human norovirus

SNU researchers develop the world’s most sensitive flexible strain sensor

Tiny, wireless antennas use light to monitor cellular communication

Neutrality has played a pivotal, but under-examined, role in international relations, new research shows

Study reveals right whales live 130 years — or more

Researchers reveal how human eyelashes promote water drainage

Pollinators most vulnerable to rising global temperatures are flies, study shows

DFG to fund eight new research units

Modern AI systems have achieved Turing's vision, but not exactly how he hoped

Quantum walk computing unlocks new potential in quantum science and technology

Construction materials and household items are a part of a long-term carbon sink called the “technosphere”

First demonstration of quantum teleportation over busy Internet cables

Disparities and gaps in breast cancer screening for women ages 40 to 49

US tobacco 21 policies and potential mortality reductions by state

AI-driven approach reveals hidden hazards of chemical mixtures in rivers

Older age linked to increased complications after breast reconstruction

ESA and NASA satellites deliver first joint picture of Greenland Ice Sheet melting

Early detection model for pancreatic necrosis improves patient outcomes

Poor vascular health accelerates brain ageing

[Press-News.org] Impact of Covid-19 pandemic on incidence of long-term conditions in Wales
Population data linkage study using anonymised primary and secondary care health records reveals that in 2020 and 2021 fewer people in Wales were being diagnosed with long-term conditions than expected.